Clinical trials: Chronic Coronary Disease
Chronic Obstructive Pulmonary Disease Moderate, Chronic Obstructive Pulmonary Disease Severe
Respiratory and Cardiovascular Alterations in Patients With Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a lung condition characterized by chronic respiratory symptoms (dyspnoea, cough, sputum production and/or exacerbations) due to abnormalities of the airways (e.g.
- Conditions
- Chronic Obstructive Pulmonary Disease Moderate, Chronic Obstructive Pulmonary Disease Severe, Cardiovascular Diseases, Quality of Life
- Trial name
- NCT06072690
- Where
- Lithuania
- Volunteers
- 80 people
- Sponsor
- Lithuanian University of Health Sciences
Chronic Kidney Disease
Usefulness of Neutrophil Gelatinase-associated Lipocalin(NGAL) to Confirm Acute Kidney Function Decrease of the Patients Who Had Non-cardiac Surgery
Although post-op renal function decrease is determined by serum creatinine, serum creatinine has disadvantages that it increases a long time after renal function decrease and it has various increasing time based on the level of…
- Trial name
- NCT02233010
- Testing
- The level of NGAL after pre op,post op 4hr, post op 12hr
- Volunteers
- 43 people
- Sponsor
- Inje University
Cardiovascular Diseases, Kidney Transplant; Complications
Cardiovascular Risk Assessment For Kidney Transplantation - Utility of Computed Tomography Coronary Angiography in the Assessment of Patients Awaiting Kidney Transplantation
Cardiovascular disease (for example, heart attack, stroke, heart failure) is the commonest complication of kidney failure. Kidney transplantation reduces cardiovascular risk but cardiovascular disease remains the commonest cause…
- Trial name
- CRAFT-CTCA (NCT06234410)
- Testing
- Computed tomography coronary angiography (CTCA)
- Where
- 5 sites in United Kingdom
- Volunteers
- 332 people
- Sponsor
- University of Edinburgh
Chronic Heart Failure
Effect of an Eccentric Exercise Program on Quality of Life and Function in People With Chronic Heart Failure.
Many studies have shown that exercise training is beneficial for patients with chronic heart failure (CHF). Heart Foundation guidelines strongly recommend regular physical activity and referral to a specifically designed…
- Trial name
- NCT02223624
- Testing
- walking and light weights, eccentric aerobic exercise, concentric aerobic exercise
- Where
- Australia
- Volunteers
- 47 people
- Sponsor
- La Trobe University
Decompensated Chronic Heart Failure
Observational Study Designed to Detect Decompensation of Congestive Heart Failure (dCHF) Using a Non-Invasive Wearable Device
This is a prospective, observational pilot study designed to develop a mathematical algorithm capable of predicting decompensation of congestive heart failure (dCHF) using physiologic data collected from a non-invasive wearable…
- Trial name
- NCT07350759
- Testing
- wearable ring device with multiple embedded sensors to detect heart rate, SVO2, respiratory rate, heart rate variability and a number of other related physiologic parameters
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- CHFDX,Inc.
Chronic Kidney Diseases, Renal Failure
IntraRenal HEmoDynamics to IntegraTE CA-AKI Risk and Monitor NephroprotectiIoN by ImpElla Support.
the hypothesis is that elevation of the intrarenal resistive index (RI) characterizes patients at elevated risk for subsequent CA-AKI and integrates items of the Mehran AKI risk score into a single, readily obtainable parameter.
- Conditions
- Chronic Kidney Diseases, Renal Failure, Coronary Artery Disease
- Trial name
- NCT06599424
- Testing
- Observational
- Where
- 2 sites in Germany
- Volunteers
- 550 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Ischemic Heart Disease, Dyslipidemias
Study of Lipid Profile of Patients With Chronic Coronary Syndromes at Sohag University Hospital
Chronic coronary syndrome (CCS) is a newly described classification devised by the European Society of Cardiology (ESC) 2019 to replace the term "Stable Coronary Artery Disease (CAD).
- Trial name
- NCT04977089
- Testing
- lipid profile test .
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Coronary Artery Disease, Diabetes Mellitus
Study Design of 'Influence of Sarpogrelate in Patients With Renal Impairment or Diabetes Mellitus' Study
The purpose of the SERENADE trial is to evaluate the safety and efficacy of sarpogrelate in patients with CKD or DM after DES implantation.
- Conditions
- Coronary Artery Disease, Diabetes Mellitus, Renal Insufficiency, Chronic
- Trial name
- SERENADE (NCT02294643)
- Testing
- Sarpogrelate, Aspirin, Clopidogrel
- Where
- South Korea
- Volunteers
- 220 people
- Sponsor
- Seoul National University Bundang Hospital
Diabetes, Chronic Kidney Diseases
Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY)
This research programme seeks to combine the resources of NHS primary care, with the leading spectroscopic work in low-magnetic fields of the Wilson Group (Nottingham Trent University) to demonstrate the potential for benchtop…
- Conditions
- Diabetes, Chronic Kidney Diseases, Cancer, Bowel Disease
- Trial name
- BRANCH-P (NCT05473325)
- Where
- United Kingdom
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Willows Health
Chronic Obstructive Pulmonary Disease
The Microcirculatory Characteristics of the Heart and Lung Meridians: A Study of COPD Patients and Healthy Adults
Although some important progresses were made in the field of the meridian research, no breakthroughs have been achieved. Besides,there are some problems in meridian researches.
- Trial name
- NCT04242030
- Testing
- Moxibustion, Laser doppler flowmetry
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Zhejiang Chinese Medical University
Ventricular Assist Device, Self-management
Improved Self-management for Patients on Ventricular Assist Device (VAD)
The number of patients with end-stage heart disease requiring the implantation of ventricular assist devices (VAD) is steadily increasing.
- Conditions
- Ventricular Assist Device, Self-management, Psychological Factors
- Trial name
- SELMA (NCT04234230)
- Testing
- Prevalence Survey
- Where
- 4 sites in Germany
- Volunteers
- 393 people
- Sponsor
- University of Freiburg
Cardiogenic Shock, Renal Replacement Therapy
REnal reCOVery After ECMO for Cardiogenic Shock (RECOVECMO)
This retrospective study assesses long term renal outcome in patients having suffered medical or post cardiotomy refractory cardiogenic shock requiring renal replacement therapy (RRT) concomitant with veno-arterial extracorporeal…
- Conditions
- Cardiogenic Shock, Renal Replacement Therapy, Venoarterial Extracorporeal Membrane Oxygenation
- Trial name
- RECOVECMO (NCT05788211)
- Testing
- standard of care
- Where
- France
- Volunteers
- 93 people
- Sponsor
- University Hospital, Bordeaux
Cardiovascular Diseases, End Stage Renal Disease
Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates
The Canadian Australasian Randomized Trial of Screening Kidney Transplant Candidates for Coronary Artery Disease (CARSK) will test the hypothesis that eliminating the regular use of non-invasive screening tests for CAD AFTER…
- Conditions
- Cardiovascular Diseases, End Stage Renal Disease, Kidney Transplantation, Dialysis Related Complication
- Trial name
- CARSK (NCT03674307)
- Testing
- No screening, Regular Screening
- Where
- 22 sites in United States, Canada and 2 more
- Volunteers
- 3,306 people
- Sponsor
- University of British Columbia
Heart Failure
Genetic and Immunity in Heart Failure
Heart failure is a major health problem with serious consequences on mortality and morbidity worldwide. In chronic heart failure an alteration of the inflammatory state occur.
- Trial name
- GISCO (NCT06758128)
- Testing
- Evaluation of HS1,2 polymorphisms
- Where
- 2 sites in Italy
- Volunteers
- 215 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Congestive Heart Failure, Anemia
Impact of Darbepoetin Alfa on Exercise Tolerance and Left Ventricular Structure in Subjects With Symptomatic Congestive Heart Failure (CHF) and Anemia
The purpose of this study was to evaluate the effect of treatment with darbepoetin alfa on peak oxygen consumption (peak VO2) in subjects with symptomatic CHF and anemia.
- Trial name
- NCT00117234
- Testing
- darbepoetin alfa
- Sponsor
- Amgen
Stroke, Cardiovascular
Cardiovascular Effects of Acute Exercise Post-Stroke
There is an urgent need to reduce the impact of stroke by promoting optimal rehabilitation strategies that decrease the risk of stroke.
- Trial name
- ACES (NCT03570216)
- Testing
- Cardiopulmonary exercise test, Moderate-intensity continuous exercise, High-intensity interval exercise
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- McMaster University
Heart Failure
Water Immersion in Chronic Stable Heart Failure
This study aims to investigate the effects of water immersion and exercise on heart function and blood flow in patients with chronic stable heart failure.
- Trial name
- IMMERSE-HF (NCT02949544)
- Testing
- water immersion
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Chronic Kidney Diseases, Heart Failure With Preserved Ejection Fraction
Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease
The goal of this study is to better understand the effects of a sodium-glucose transport protein 2 inhibitor, dapagliflozin, added on to standard of care on heart and lung function and circulating metabolites (substances created…
- Conditions
- Chronic Kidney Diseases, Heart Failure With Preserved Ejection Fraction, Kidney Diseases, Heart Failure
- Trial name
- NCT05719714
- Testing
- Dapagliflozin 10 MG [Farxiga]
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Northwestern University
Ischemic Heart Disease, Acute Coronary Syndrome
Continuity of Care Between Primary Care Cardiology and Specialty Services for Patients With Chronic Ischemic Heart Disease
1.1. Background Cardiovascular disease (CVD) remains the leading cause of death in our country for over four decades. The pathophysiology of CVD begins with various cardiovascular risk factors (CRFs) and their poor management…
- Trial name
- CAPRICI (NCT06421363)
- Testing
- Inclisiran
- Where
- 6 sites in Spain
- Volunteers
- 50 people
- Sponsor
- Jose Seijas Amigo
Acute Myocardial Infarction, Diabetes Mellitus
Association of Long-term Conditions With Survival Following Heart Attack in England and Wales
This study aims to determine the extent to which pre-existing long-term conditions are associated with survival following a heart attack (acute myocardial infarction) using observational data from the UK's national heart attack…
- Conditions
- Acute Myocardial Infarction, Diabetes Mellitus, Peripheral Vascular Disease, Chronic Heart Failure
- Trial name
- NCT03037255
- Testing
- long term conditions
- Volunteers
- 693,633 people
- Sponsor
- Marlous Hall
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