Clinical trials: Chronic Coronary Disease
Chronic Obstructive Pulmonary Disease
The Difference in the Biological Characteristic Characteristics of the Heart and Lung Meridians
The association between viscera and the body surface remains obscure, but a better understanding of it will maximize its diagnostic and therapeutic values in clinical practice.
- Trial name
- NCT05690217
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Sudden Cardiac Death, End Stage Renal Disease
T-Wave Alternans in Dialysis Patients
Sudden cardiac death due to arrhythmia is the leading cause of death in end-stage renal disease (ESRD) patients treated with hemodialysis (HD).
- Trial name
- NCT00621426
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwestern University
Coronary Artery Disease, Chronic Heart Failure
Long-tErm Effects of Enhanced eXternal CountErpuLsation
Enhanced external counterpulsation (EECP) is an effective non-invasive treatment in patients with coronary artery disease (CAD) which complicated by chronic heart failure (CHF).
- Trial name
- EXCEL (NCT05913778)
- Testing
- Enhanced external counterpulsation
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Diabetes, Cholesterol
Interprofessional Pharmacogenomics (IPGx) Registry and Repository
This program collects genetic and health information to help doctors choose the right medications for patients.
- Conditions
- Diabetes, Cholesterol, Cancer, Blood Pressure Disorders
- Trial name
- IPGx Registry (NCT06726590)
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Texas A&M University
Cerebral Palsy
Effect of Posture and Passive Cycling on Cardiac Autonomic Control System in Children With Severe Cerebral Palsy
The investigators will examine the immediate contribution of position and movement on the functioning of the autonomic cardiac control system.
- Trial name
- NCT02599025
- Testing
- Innowalk cycling system, APT cycling system
- Volunteers
- 24 people
- Sponsor
- Ziv Hospital
Premature Baby, Pulmonary Hypertension of Newborn
Measuring Heart Health in Both Term, Preterm and Unwell Newborn Babies With an Advanced Ultrasound Method: Speckle Tracking Echocardiography
This study aims to improve how neonatologists check the heart function of newborn babies, especially those who are sick. While standard heart ultrasound scans are useful, a more advanced and sensitive technique called 2D speckle…
- Conditions
- Premature Baby, Pulmonary Hypertension of Newborn, Hypoxic Ischaemic Encephalopathy (HIE), Congenital Diaphragmatic Hernia
- Trial name
- NCT07364682
- Where
- United Kingdom
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's NHS Foundation Trust
Diabetes Mellitus Type 2, Coronary Artery Diseases
Comparison of Effects of Buffered and Enteric-coated Forms of Aspirin on Platelet Aggregation in Patients With Diabetes Mellitus and Chronic Coronary Syndrome
Patients with diabetes mellitus are characterized by "hyperreactive" platelets and a reduced response to ASA compared to individuals without diabetes.
- Conditions
- Diabetes Mellitus Type 2, Coronary Artery Diseases, Aspirin Resistance
- Trial name
- CASCADE (NCT06716255)
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Nizhpharm
Chagas Disease, Chagas Cardiomyopathy
Physical Exercise Program in Chronic Chagas Heart Disease
The aim of this investigation is to evaluate the impact of exercise in a cardiac rehabilitation program on functional capacity, clinical markers, quality of life and biomarkers in patients with chronic chagasic cardiomyopathy.
- Trial name
- PEACH (NCT02517632)
- Testing
- Exercise, nutritional and pharmaceutical counceling, Nutritional and pharmaceutical counceling
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Evandro Chagas National Institute of Infectious Disease
Chronic Fatigue Syndrome
Clinical Trial to Measure the Maximun HR After ReConnect ® Supplementation vs. Placebo in CFS.
The main objective is evaluate to safety and efficacy of oral Reconnect ® (food supplementation composed by Coenzyme Q10, NADH, phosphoserine y vitamin C) on the maximum HR during an exercise test in CFS
- Trial name
- ReConnect (NCT02063126)
- Testing
- ReConnect (NADH plus CoQ10)
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Heart Failure, Cardiomyopathies
International T1 Multicenter Outcome Study
Mapping of magnetic relaxation within the myocardial tissue using T1 (and T2) mapping using cardiovascular magnetic resonance (CMR) are novel measures of quantifiable (scalable) myocardial tissue characterisation.
- Conditions
- Heart Failure, Cardiomyopathies, Inflammatory Disease, Coronary Artery Disease
- Trial name
- T1Outcome-DE (NCT03749343)
- Where
- 2 sites in Germany
- Volunteers
- 8,000 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Cardiovascular Disease, Coronary Artery Disease
Radial Artery Versus Saphenous Vein Grafts in Coronary Artery Bypass Surgery
VA patients with coronary artery disease and who have agreed to undergo coronary artery bypass graft surgery would be randomized to receive either radial artery or saphenous vein to the study vessel.
- Trial name
- NCT00054847
- Testing
- saphenous vein graft, radial artery graft
- Where
- 11 sites in United States
- Volunteers
- 733 people
- Sponsor
- US Department of Veterans Affairs
Chronic Disease, Kidney Diseases
A Study to Evaluate Whether Correction of Anemia Using Recombinant Human Erythropoietin Reduces the Progression of Atherosclerosis and Cardiac Hypertrophy in Pre-dialysis Chronic Kidney Disease Patients
The primary aim of the study is to evaluate the effects of correction of anemia using erythropoietin on the progression of atherosclerosis and cardiac muscle thickening in patients with chronic kidney disease
- Conditions
- Chronic Disease, Kidney Diseases, Cardiovascular Diseases
- Trial name
- NCT00563355
- Testing
- erythropoietin
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Hospital Authority, Hong Kong
Chronic Lung Disease, Chronic Heart Disease
Integral Clinical Plan Shared With or Without Telemonitoring of Constants in Patient With Chronic Diseases
Information and communications technologies (ICT) currently constitute a key element in the innovation and improvement of providing health-care to frail populations with advanced chronic diseases, but it´s efficacy, safety and…
- Trial name
- ATLAN_TIC01 (NCT03018717)
- Testing
- Telemonitoring Constant, Standard clinical care
- Where
- 5 sites in Spain
- Volunteers
- 510 people
- Sponsor
- Fundación Pública Andaluza Progreso y Salud
Cardiovascular Diseases, Acute Coronary Syndrome
The IndONEsia ICCU Registry: a Multicenter Cohort of Intensive Cardiovascular Care Units Patients in Indonesia
Patients in the Intensive Cardiovascular Care Unit (ICCU) often present with cardiovascular disease (CVD) issues accompanied by various non-cardiovascular conditions.
- Conditions
- Cardiovascular Diseases, Acute Coronary Syndrome, Heart Failure, Heart Disease, Coronary
- Trial name
- NCT06265714
- Where
- 9 sites in Indonesia
- Volunteers
- 12,950 people
- Sponsor
- Universitas Indonesia
Coronary Heart Disease (CHD)
Single vs. Dual Antiplatelet Therapy in Patients Undergoing Percutaneous Intervention With DCB-only Strategy (KONG-FREEDOM-I)
This investigator-initiated, multicenter, open-label, randomized clinical trial evaluates the safety and efficacy of single antiplatelet therapy (SAPT) utilizing a P2Y12 inhibitor compared to dual antiplatelet therapy (DAPT) in…
- Trial name
- KONG-FREEDOM-I (NCT07587099)
- Testing
- Drug-coated balloon, Single antiplatelet therapy (SAPT), Dual antiplatelet therapy (DAPT)
- Where
- 14 sites in China
- Volunteers
- 2,170 people
- Sponsor
- Gan Lijun
Covid19, SARS-CoV-2 Infection
Analysis of Chronic Non-infectious Diseases Dynamics After COVID-19 Infection in Adult Patients
Non-commercial depersonalized multi-centered registry study on analysis of chronic non-infectious diseases dynamics after SARS-CoV-2 infection in adults.
- Conditions
- Covid19, SARS-CoV-2 Infection, Pneumonia, Copd
- Trial name
- ACTIV (NCT04492384)
- Testing
- non-interventional
- Where
- Russia
- Volunteers
- 6,396 people
- Sponsor
- Eurasian Association of Therapists
Congenital Complete Atrioventricular Heart Block, High Grade Atrioventricular Block
Effects of Chronic Right Ventricular Pacing in Children With Advanced Atrioventricular Block
Recent studies have shown that chronic stimulation of the right ventricle can cause deleterious effects to cardiac function and synchronicity.
- Conditions
- Congenital Complete Atrioventricular Heart Block, High Grade Atrioventricular Block, Postoperative Complete Heart Block
- Trial name
- NCT01477658
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- University of Sao Paulo
Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck, Melanoma Neoplasms
Evaluation of Skin Tests in Biotherapy Allergies
Biotherapies are biological (extracted from an organism or living tissue) or biotechnological drugs used in the treatment of multiple conditions, such as autoimmune inflammatory diseases, cancers, and hematologic diseases.
- Conditions
- Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck, Melanoma Neoplasms, Small Cell Bronchial Carcinomas, Bronchial Carcinoma
- Trial name
- ETCABIO (NCT06971848)
- Testing
- Drug skin tests (investigating hypersensitivity to a biotherapy)
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Chagas Cardiomyopathy
Effects of Omega-3 Supplementation on the Cytokine and Lipid Profiles in Patients With Chronic Chagas Cardiomyopathy
The objective of this trial is to study the effects of omega-3 PUFA supplementation on the inflammatory response and lipid profile in patients with chronic Chagas cardiomyopathy.
- Trial name
- NCT01863576
- Testing
- Omega-3
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Evandro Chagas Institute of Clinical Research
Cardiorenal Syndrome (CRS)
Screening of Predictive Biomarkers for Cardiorenal Syndrome
This study aims to explore the predictive value of specific biomarkers for cardiorenal syndrome (CRS) in patients with chronic heart failure (CHF).
- Trial name
- NCT07139626
- Testing
- This is an observational Study.
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Haiyan Pan
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