Clinical trials: Chronic Depression
Musculoskeletal Diseases, Chronic Pain
Wellness Through Mobile Health
This pilot project will evaluate the potential of an affordable smartphone app to improve users' mental well-being.
- Conditions
- Musculoskeletal Diseases, Chronic Pain, Anxiety Disorders, Depression
- Trial name
- NCT04640090
- Testing
- Smartphone app (Wysa)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Washington University School of Medicine
Depression
Psycho-behavioral Intervention for Depression in Chronic Heart Failure
The study aims to explore the effectiveness of psycho-behavioral intervention on depressive symptoms among older adults with chronic heart failure.
- Trial name
- NCT03233451
- Testing
- Psycho-behavioral intervention
- Where
- 6 sites in China
- Volunteers
- 236 people
- Sponsor
- Peking University
Chronic Depression
Getting Biased Treatment Study: How Psychotherapy and Antidepressants Change Brain Activity in Chronic Depression
The purpose of this study is to determine how psychotherapy and pharmacotherapy respectively change brain activity in patients suffering from chronic depression.
- Trial name
- GETTY (NCT00596986)
- Testing
- Duloxetine, Cognitive Behavioural Analysis System of Psychotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Charite University, Berlin, Germany
Chronic Pain, Depression
Mindfulness-based Cognitive Therapy vs the Health Enhancement Program for Chronic Pain and Depression; The Quiet Focus Study
The goal of this clinical trial is to pilot a randomized controlled trial comparing an adaptation of mindfulness-based cognitive therapy to the health enhancement program for chronic pain and depression.
- Trial name
- NCT07118722
- Testing
- Quiet Focus, Health Enhancement Program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Coccyx Injuries, Pain, Chronic
The Relationship of Disability With Depression, Anxiety and Sleep Quality in Patients With Coccygodynia
Pain of the sacrococcygeal region is called coccygodynia This painful clinical picture, which causes a decrease in the quality of life, also causes disability.
- Conditions
- Coccyx Injuries, Pain, Chronic, Anxiety, Depression
- Trial name
- NCT05047380
- Testing
- Owstery Disability Scale for disability Beck Depression Scale, Beck Anxiety Scale for psychological evaluation, VAS for pain, Pittsburgh Sleep Quality Scale for sleep quality
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Cumhuriyet University
Cirrhosis
Remote Electrical Stimulation for Pain and Depression Treatment in Cirrhosis
This study is being done to better understand how the study team can treat pain for people with cirrhosis and depression. Enrolled participants on this feasibility study will be randomized to Transcutaneous Electrical…
- Trial name
- RESTORE (NCT06932783)
- Testing
- Transcutaneous Electrical Acustimulation (TEA)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Michigan
Depression, Family Dynamics
The Mental Health Effects of a Mindfulness App in Parents of a Child With Medical Complexity
The number of children with special health care needs (CSHCN) in the US is nearly 20% of children representing approximately 14.6 million children nationally.
- Conditions
- Depression, Family Dynamics, Stress, Psychological, Chronic Illness
- Trial name
- NCT05925868
- Testing
- mindfulness app
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Boise State University
Depression Symptoms, Chronic Pain
Effect of Auricular Press Needle on Improvement of Patient Health Questionnaire-9 (PHQ-9) and Heart Rate Variability (HRV) Patient With Depression Symptoms in Chronic Pain
Depression is characterized by behavioral, cognitive and emotional changes. Depression can have a negative impact on decreasing quality of life because in many cases it occurs long-term.
- Trial name
- NCT06401070
- Testing
- Plesterin, Press needle acupuncture
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
Chronic Pain
A Depression and Opioid Pragmatic Trial in Pharmacogenetics (Chronic Pain Trial)
This study is comprised of three separate pharmacogenetic trials grouped into a single protocol due to similarities in the intervention, the hypotheses, and the trial design.
- Trial name
- ADOPT PGx (NCT05966142)
- Testing
- Pharmacogenetic testing, Clinical decisions support
- Where
- 10 sites in United States
- Volunteers
- 1,048 people
- Sponsor
- Duke University
Chronic Disease, Risk Reduction
Nature and Health: How Does Lifestyle and Environment Affect Health and Wellness
The purpose of this study is to examine if and how implementing nature prescriptions can increase time in nature and improve health to yield an actionable understanding of the nature-health connection.
- Conditions
- Chronic Disease, Risk Reduction, Mental Health Wellness 1, Physical Inactivity
- Trial name
- NCT06001697
- Testing
- Park prescription, Regular health advice
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Stanford University