Clinical trials: Chronic Disease (Physical)
Neuropathic Pain
Can the Perception of a Treatment Influence Pain Processing - an Examination of Psychological and Neurobiological Mechanisms
The study investigates the effect of an open (in full view of the patient) vs hidden treatment (without the patient's knowledge).
- Trial name
- NCT03109860
- Testing
- Open-hidden
- Volunteers
- 19 people
- Sponsor
- University of Aarhus
Respiration, Artificial, Critical Illness
Development of a Rehabilitation Strengthening and Mobility Program for Ventilator Dependent Older Patients
As the general population ages and technology advances, many who suffer from catastrophic critical illness (i.e. septic shock, respiratory failure, Acute Respiratory Disease Syndrome) survive only to find themselves severely…
- Conditions
- Respiration, Artificial, Critical Illness, Chronic Disease, Exercise Therapy
- Trial name
- NCT03195127
- Testing
- multimodal physical therapy
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Maryland, Baltimore
Opioid-use Disorder, Opioid-related Disorders
An Observational Study of Environmental and SocioEconomic Factors in Opioid Recovery
The RECOVER Study will examine clinical, environmental and socioeconomic factors in recovery from opioid use disorder (OUD) over a 24-month period following exit from a Phase III clinical program for a buprenorphine…
- Trial name
- RECOVER® (NCT03604861)
- Testing
- Not applicable - no defined intervention
- Where
- 35 sites in United States
- Volunteers
- 534 people
- Sponsor
- Indivior Inc.
COVID-19, Long Haul
Digital Cognition Study During Long-COVID
The persistence of the COVID-19 disease symptoms, such as extreme fatigue, shortness of breath, cardiovascular complications, depression and anxiety, pain, brain fog, loss of taste/smell, headaches as well as loss of memory has…
- Trial name
- DIGICOG (NCT06391970)
- Testing
- Cognitive screening
- Where
- Luxembourg
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Luxembourg Institute of Health
Stroke, Osteopathic Medicine
Examining Relationships Between Musculoskeletal Function Measurements of Movement Efficiency and Nervous System Function After Chronic Stroke
Stroke remains the leading cause of severe disability, and survivors frequently have incomplete recovery. More than half of older survivors have impaired mobility which contributes to poorer quality-of-life (QoL) and suffering.
- Conditions
- Stroke, Osteopathic Medicine, Physical Examination, Heart Rate Variability (HRV)
- Trial name
- SOMADC-CC (NCT07737873)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Davis
Exercise Therapy, Behavior and Behavior Mechanisms
Health-Enhancing Adapted Physical Activity Program at "Mon Stade"
Introduction: Regular practice of exercise or physical activity (PA) is a recognized intervention as a determinant of good health acquisition, maintenance, or recovery for a large number of chronic pathologies.
- Conditions
- Exercise Therapy, Behavior and Behavior Mechanisms, Adherence, Patient, Lifestyle, Sedentary
- Trial name
- SESAME (NCT04716322)
- Testing
- Adapted Physical Activity
- Where
- France
- Volunteers
- 2,024 people, healthy volunteers welcome
- Sponsor
- Mon Stade Sports Medicine Centre
COPD, Chronic Musculoskeletal Pain
BRAIN, Symptoms, and Physical Activity in COPD
Persons with COPD have both chronic musculoskeletal pain and dyspnea that require accurate diagnosis and treatment, ultimately to optimize functional status.
- Trial name
- BRAIN-SPA (NCT04291131)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- VA Office of Research and Development
Rheumatoid Arthritis (RA, Ankylosing Spondylitis
Skin Autofluorescence Assessment of Advanced Glycation End Products in Rheumatic Diseases
Rheumatic diseases are chronic inflammatory conditions that can lead to long-term tissue damage and increased cardiovascular and metabolic risk.
- Conditions
- Rheumatoid Arthritis (RA, Ankylosing Spondylitis, Psoriatic Arthritis, Reactive Arthritis (ReA)
- Trial name
- NCT07329556
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bursa City Hospital
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting
Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis
The purpose of this research is to support the clinical value of the Cionic Neural Sleeve for individuals diagnosed with multiple sclerosis (MS).
- Conditions
- Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Chronic Progressive
- Trial name
- NCT05964829
- Testing
- Cionic Neural Sleeve NS-100, Walking Program
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Cionic, Inc.
Chronic Pain
Understanding the Determinants of Physical Activity Levels in Persons With Chronic Pain
The proposed research topic will investigate the determinants of physical activity (PA) levels in patients with chronic pain. The aim of the research project is to quantify the self-reported and free-living physical activity…
- Trial name
- NCT04855461
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Glasgow Caledonian University
Chronic Periodontitis, Aggressive Periodontitis
Estimation of Pentrexin-3 Levels in GCF and Saliva of Patients With Periodontal Disease
Subjects were selected from the outpatient clinic, Department of Oral Medicine and Periodontology, Faculty of Oral and Dental Medicine, Cairo University.
- Trial name
- NCT03128502
- Volunteers
- 40 people
- Sponsor
- Cairo University
Chronic Obstructive Pulmonary Disease
Impact of a Hospital Physical Therapy Program on Chronic Obstructive Pulmonary Disease (COPD) Patients
The Chronic Obstructive Pulmonary Disease is a leading global cause of morbidity and mortality, so it's important to find actions that could improve quality of life and decrease the mortality.
- Trial name
- NCT01295359
- Testing
- Ground Walking Program
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Federal de Sao Carlos
Chronic Obstructive Pulmonary Disease, Asthma
Video vs. TTG Respiratory Inhaler Technique Assessment and InstructioN (V-TRaIN)
The purpose of this study is to evaluate the effectiveness of two different ways to teach subjects while hospitalized how to use respiratory inhalers and to follow-up after discharge home from the hospital to determine durability…
- Trial name
- NCT02611531
- Testing
- Video Module Education (VME), Teach-To-Goal (TTG)
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- University of Chicago
Chronic Myeloid Leukemia (CML)
Metabolic Outcomes in Patients Receiving Tyrosine Kinase Inhibitor (TKI) Therapy With Dasatinib or Nilotinib
The purpose of this study was to determine how often and how likely patients are to develop Type 2 Diabetes or high cholesterol/lipids when receiving dasatinib or nilotinib as therapy for Chronic Myelogenous Leukemia (CML).
- Trial name
- NCT02733445
- Testing
- dasatinib, nilotinib
- Volunteers
- 2,650 people
- Sponsor
- Bristol-Myers Squibb
Chronic Kidney Disease, Cardiovascular Diseases
SEDentary Lifestyle, Mortality and Major Adverse Clinical Outcomes in Chronic KIDney Disease
The goal of this study is to learn if a simple home exercise program can benefit patients with advanced chronic kidney disease. There is also an observational part of the study without an exercise program.
- Conditions
- Chronic Kidney Disease, Cardiovascular Diseases, Frailty
- Trial name
- SEDKID (NCT06935786)
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION
- Where
- 3 sites in Finland
- Volunteers
- 400 people
- Sponsor
- Turku University Hospital
Assessment, Self, Cerebral Palsy
Assessment by Surface Electromyography in Cerebral Palsy Footballers
Adapted sport is constantly evolving thanks to the technological and scientific advances in the field of sports that are being developed in our era.
- Conditions
- Assessment, Self, Cerebral Palsy, Technology Addiction
- Trial name
- NCT06151873
- Testing
- Adapted sport
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension
Prognostic Value of Estimated Plasma Volume in Pulmonary Hypertension
Assessment of the prognostic value of the estimation of plasma volume or its variation in patients with pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH) after acute right heart…
- Conditions
- Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Acute Right Heart Failure
- Trial name
- NCT05861479
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
Cerebral Palsy, Quality of Life
Health Related Lifestyle and Quality of Life in Children With Cerebral Palsy
The primary aim of this study is assessing physical activity, the quality of sleep and health related quality of life in children with cerebral palsy, and parenting stress of caregivers of the children with cerebral palsy in…
- Conditions
- Cerebral Palsy, Quality of Life, Physical Activity, Physical Disability
- Trial name
- NCT03277027
- Testing
- interventional study
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- The Catholic University of Korea
Chronic Obstructive Pulmonary Disease
Long-term Effect of an Health Education Program on Daily Physical Activity in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Main objective: To compare the level of physical activity (PAL) at 12 months in patients with moderate to very severe chronic obstructive pulmonary disease (COPD) between those who completed a health education program and those…
- Trial name
- EA-EPOC (NCT02924870)
- Testing
- Health education program, Conventional management
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- Hospital Universitario La Paz
Venous Disease Classification (CEAP): C2 or C3
EXPLORATORY ASSESSMENT OF THE EFFECTS OF CYCLO 3 ® FORT (Ruscus Extract, Hesperidin Methyl Chalcone, Ascorbic Acid) OR MICRONISED PURIFIED FLAVONOID FRACTION ON VASCULAR PARAMETERS AND BIOMARKERS IN WOMEN SUFFERING FROM CHRONIC VENOUS DISEASE (CEAP C2 OR C3), OVER 8 WEEKS
Chronic Venous Disorder is the most prevalent vascular disease. It is multifactorial pathology that has an important impact on quality of life and represents a significant public health concern, due to its very high frequency in…
- Trial name
- NCT02907320
- Testing
- CYCLO 3 ® FORT, MPFF
- Sponsor
- Pierre Fabre Medicament