Clinical trials: Chronic Disease (Physical)
Nutrition Disorders, Gastrointestinal Disease
Review of Infant Oral Feeding and Skills
This study evaluates the infant's feeding skill level at discharge from the neonatal intensive care unit. The goal is to determine whether the ability to "full feed by volume" implies "full skill development" for infant oral…
- Conditions
- Nutrition Disorders, Gastrointestinal Disease, Deglutition Disorder, Feeding Difficulties
- Trial name
- RIOS (NCT06736743)
- Testing
- SMART Tool for Feeding Skill Assessment
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Wake Forest University Health Sciences
Chronic Obstructive Pulmonary Disease (COPD)
Home-monitoring and Adherence of Patients With COPD to Long-term Rehabilitation
The aim of this randomized controlled trial is to investigate the effects of adding PA monitoring and regular feedback of a pedometer (step counter) to an outpatient pulmonary rehabilitation (PR) program on daily PA levels and…
- Trial name
- NCT02122614
- Testing
- Pulmonary rehabilitation (PR) plus PA monitoring and feedback from a pedometer, Pulmonary rehabilitation (PR)
- Where
- Portugal
- Volunteers
- 32 people
- Sponsor
- Aveiro University
Lyme Borreliosis, Physical Activity
Effectiveness of an Intervention Combining Adapted Physical Activity and Therapeutic Education in Patients With Chronic Symptoms Attributed to Lyme Borreliosis.
Lyme borreliosis, commonly known as Lyme disease, has been clinically described for more than a century, but has been officially recognized for 40 years, with the detection of the Borrelia bacterium by W.
- Conditions
- Lyme Borreliosis, Physical Activity, Lyme Borreliosis, Nervous System
- Trial name
- LyMouv' (NCT05641116)
- Testing
- physical activity program, Advice and recommendations of physical activity at home
- Where
- 2 sites in France
- Volunteers
- 62 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Spina Bifida, Cerebral Palsy
Children and Teens in Charge of Their Health
This three year study explores the feasibility and acceptability of conducting a full randomized controlled trial (RCT) of a promising coaching intervention for improving and sustaining physical activity (PA) and healthy dietary…
- Conditions
- Spina Bifida, Cerebral Palsy, Health Behavior
- Trial name
- CATCH (NCT03523806)
- Testing
- Solution-Focused Coaching in Pediatric Rehabilitation
- Where
- 2 sites in Canada
- Volunteers
- 16 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Chronic Kidney Disease
Low-protein Formula Supplements in Chronic Kidney Disease
Prospective randomized contorl study.Comparing clinical outcome between chronic kidney disease who were prescribed 6% low-protein nutrition supplement along with dietatian regular nutrition education and those without oral…
- Trial name
- NCT05318014
- Testing
- Intervention group, Regular nutrition education
- Where
- Taiwan
- Volunteers
- 95 people
- Sponsor
- Taichung Veterans General Hospital
Juvenile Idiopathic Arthritis, Diabetes
Health and Exercise Response in Children With Chronic and Auto-immune Pathologies
The aim of the present project is to assess the effects of the chronic diseases and their associated treatments chronic paediatric diseases (CPD), to further understand their impact on physical fitness for public health…
- Conditions
- Juvenile Idiopathic Arthritis, Diabetes, Inflammatory Bowel Disease, Cancer Survivor
- Trial name
- HERCCULE (NCT03913962)
- Testing
- indirect calorimetry
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
End Stage Renal Disease
A Comparison of Physical Activity Levels With and Without Feedback Via Fitbit® Flex™ in Hemodialysis Patients
This is a pilot study intended to gather data in order to inform future studies about the role of feedback as an incentive for increasing levels of physical activity which could improve health in hemodialysis patients.
- Trial name
- IAM (NCT02320513)
- Testing
- Wearing activty monitoring device (Fitbit Flex), Fitbit Flex
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Renal Research Institute
Chronic Obstructive Pulmonary Disease, Endothelial Dysfunction
Micro-doses of Physical Activity for COPD
Chronic obstructive pulmonary disease (COPD) is a disease of the lungs that makes it hard for people to breath. Those with COPD spend considerably more time sitting and lying and less time performing physical activity than…
- Conditions
- Chronic Obstructive Pulmonary Disease, Endothelial Dysfunction, Vascular Stiffness, Hypertension
- Trial name
- COPD (NCT05553223)
- Testing
- Microdoses of activity
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Multiple Sclerosis, Primary Progressive
Cognition Evolution and MRI Markers in PPMS Patients on 2 Years
Cognitive impairment is nowadays more and more recognized as an important feature of the multiple sclerosis (MS) disease. Cognitive disorders frequency in MS is estimated between 40 and 60%.
- Trial name
- PRO-COG (NCT03455582)
- Testing
- Clinical assessment, Ecological evaluation, Neuropsychological evaluation
- Where
- 3 sites in France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
COPD, Inactivity, Physical
Actimetry Protocol in COPD Patients
Recently, the principal investigator published an EI predictive Machine Learning algorithm based solely on clinical data, without any physical activity measures, collected from 1 409 patients.
- Trial name
- NCT05918003
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Association pour la Complementarite des Connaissances et des Pratiques de la Pneumologie
Diabetic Nephropathies, Type 1 Diabetes Mellitus
Assessment of the Accuracy of Continuous Glucose Sensors in People With Diabetes Undergoing Haemodialysis
The purpose of the study is to assess the accuracy of the Dexcom G6 CGM system and the Abbott FreeStyle Libre flash system compared to the reference standard YSI (Yellow Spring Instruments) glucose in people with diabetes…
- Conditions
- Diabetic Nephropathies, Type 1 Diabetes Mellitus, Chronic Kidney Diseases
- Trial name
- ALPHA (NCT03885362)
- Testing
- Dexcom G6 and Abbott Freestyle Libre
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Imperial College London
Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia
Spectroscopic Assessment of Tissue Oxygenation Changes During Vascular Surgery
This study is a single-center, observational study designed to collect tissue spectrometric data related to tissue oxygenation.
- Conditions
- Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia, Ischemia Vascular, Tissue Ischemia
- Trial name
- NCT07786623
- Volunteers
- 30 people
- Sponsor
- Spectrocor
Chronic Pain, Osteoarthritis
A Mobile Intervention to Reduce Pain and Improve Health-III
The experience of chronic pain powerfully and negatively affects quality of life and functional independence in aging. Unfortunately, while as many as three in four older adults experience chronic pain, few have access to…
- Conditions
- Chronic Pain, Osteoarthritis, Obesity and Overweight, Inactivity
- Trial name
- MORPH-III (NCT06623669)
- Testing
- MORPH, Measurement Only
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Wake Forest University
Tennis Elbow, Physical Therapy Modalities
Effectiveness of Radial Nerve Mobilization for Chronic Epicondylalgia
Effectiveness of radial nerve mobilization techniques and their interfaces for treating chronic epicondylalgia Intervention: This is a randomized controlled clinical trial that will evaluate the effectiveness of adding radial…
- Trial name
- NCT07146620
- Testing
- Forearm massage, Pressure release for forearm trigger points, Mulligan mobilization with movement technique
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- Universitat Internacional de Catalunya
Chronic Venous Insufficiency, CVI, Chronic Venous Insufficiency C2 or Higher
Reducing Skin Tone Inequities in Chronic Venous Insufficiency
The aim of this project is to define assessment criteria for chronic venous insufficiency (CVI) in people with dark skin tones. It will inform future interventions and modifications to practice for the assessment of CVI in people…
- Conditions
- Chronic Venous Insufficiency, CVI, Chronic Venous Insufficiency C2 or Higher, Chronic Venous Disease of Lower Limbs, Venous Leg Ulcer (VLU)
- Trial name
- NCT06798766
- Where
- 2 sites in United Kingdom
- Volunteers
- 51 people
- Sponsor
- King's College London
Ferric Compounds, Magnetic Resonance Angiography
Ferumoxytol Enhanced Magnetic Resonance Angiography in Chronic Kidney Disease
Conventional vascular imaging techniques are often either contra-indicated in chronic kidney disease (CKD) patients due to their relative invasiveness, risks and cost.
- Conditions
- Ferric Compounds, Magnetic Resonance Angiography, Vascular Grafting, Arteriovenous Fistula
- Trial name
- FeMRA in CKD (NCT02997046)
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Sokratis Stoumpos
Cerebral Palsy (CP)
Go For It: to Improve Levels of Daily Physical Activity and to Reduce the Sedentary Life Style of Adolescents With CP
Long hours of daily sitting and lack of Physical Activity (PA) are risk factors for morbidity and mortality. People with movement disabilities, including adolescents with Cerebral Palsy (CP) tend to lead a sedentary life styl and…
- Trial name
- NCT02978469
- Testing
- Life style changing: reducing sedentary behavior
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Acute Pancreatitis
Assessment of the Different Etiological and Susceptibility Markers in Patients With Pancreatitis: Investigating IG4, Cytomegalovirus, Coxsackie- Virus, Genetic Polymorphism of Vitamin D Receptor Gene
Acute pancreatitis (AP) is a multifactorial disease. AP represents a significant number of hospital admissions. Most of the patients are admitted in an acute setting.
- Trial name
- NCT03830073
- Testing
- Measurement of VDR genetic polymorphism
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
COVID-19, Long COVID
Using Data From a Multisensor Rapid Health Assessment Device to Predict Decompensation in Long COVID (AIDI)
We are conducting a research study at the VA hospital in Bedford, MA to learn more about how a multisensor rapid health assessment device, MouthLab, can help predict or anticipate future health complications in patients with…
- Trial name
- AIDI (NCT05713266)
- Testing
- MouthLabTM
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Edith Nourse Rogers Memorial Veterans Hospital
Pulmonary Disease, Chronic Obstructive
Spiriva (Tiotropium Bromide) Assessment of FEV1 - (SAFE-Portugal).
Evaluate whether the effect of inhaled tiotropium bromide on the change in trough forced expiratory volume (FEV1), compared to placebo in patients with chronic obstructive pulmonary disease (COPD), is affected by smoking status.
- Trial name
- NCT00239408
- Testing
- Pulmonary function Testing, tiotropium bromide
- Where
- 33 sites in Portugal
- Volunteers
- 311 people
- Sponsor
- Boehringer Ingelheim
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