Clinical trials: Chronic Disease (Physical)
Severe Alcoholic Hepatitis, Chronic Liver Disease and Cirrhosis
Invasive Fungal Infections in Severe Alcohol-associated Hepatitis
Chronic alcohol consumption is associated with intestinal bacterial dysbiosis, yet little is known about the role of intestinal fungi, or mycobiota in liver disease.
- Trial name
- NCT04103840
- Testing
- Testing stool mycobiota
- Where
- India
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Chronic Diseases, Hypertension
Collection of Blood and Urine Specimens From Volunteers Utilizing Health Examination Services
In summary, the researchers want to construct a longitudinal data bank using voluntary health examination participants. Researchers in the National Taiwan University Hospital (NTUH) campus can utilize these data to clarify the…
- Conditions
- Chronic Diseases, Hypertension, Diabetes, Obesity
- Trial name
- NCT00173940
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
Physical Activity, Kidney Diseases
Effects of Exercise and Exercise Counselling in Hemodialysis Patients.
The aim of the study is to determine the effect of functional exercise and training counseling by kinesiotherapist in addition to the basic exercise program of cycling during dialysis on physical performance of dialysis patients.
- Conditions
- Physical Activity, Kidney Diseases, Kidney Failure, Chronic Kidney Diseases
- Trial name
- NCT03334123
- Testing
- Functional training and cycling, Cycling
- Where
- Slovenia
- Volunteers
- 86 people
- Sponsor
- University Medical Centre Ljubljana
Renal Failure, End Stage Renal Disease
Comparison of the Human Acellular Vessel (HAV) With ePTFE Grafts as Conduits for Hemodialysis
The main purpose of this study is to compare the Human Acellular Vessel (HAV) with ePTFE grafts when used for hemodialysis access.
- Conditions
- Renal Failure, End Stage Renal Disease, Hemodialysis, Vascular Access
- Trial name
- NCT02644941
- Testing
- Human Acellular Vessel (HAV), ePTFE graft
- Where
- 38 sites in United States, Germany and 4 more
- Volunteers
- 355 people
- Sponsor
- Humacyte, Inc.
Chronic Pain, Pain
A Study of Cebranopadol for Opioid Withdrawal Symptoms in Adults With Chronic Pain
This Phase 2 study will evaluate whether multiple doses of cebranopadol suppress opioid withdrawal signs and symptoms compared with placebo in adults with chronic pain who are physically dependent on prescribed opioids.
- Conditions
- Chronic Pain, Pain, Opioid Withdrawal (Disorder), Opioid Use Disorder
- Trial name
- NCT07874620
- Testing
- Cebranopadol
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Adneuris Therapeutics, Inc.
Renal Insufficiency, Chronic
Effect of Physical Exercise Performed Through Virtual Reality Games on Chronic Renal Patients During Hemodialysis
Patients with chronic kidney diseases, especially those requiring hemodialysis, are characterized by an increased risk of numerous morbidities.
- Trial name
- NCT06038383
- Testing
- Group A - Intervention with Virtual Reality (VR), Group B - Intervention with Stationary Bike (SB), Group A - Intervention with Stationary Bike (SB) - Crossover
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- University of Sao Paulo
Frailty Syndrome
Physical Performance Assessment in Kidney Transplant Evaluation
This prospective cohort study investigates physical frailty, assessed by the Short Physical Performance Battery (SPPB), in patients evaluated for kidney transplantation.
- Trial name
- FRAIL-KTx (NCT07338929)
- Where
- Slovakia
- Volunteers
- 50 people
- Sponsor
- University Hospital, Martin
Mild Chronic Obstructive Pulmonary Disease, Respiratory Symptoms
GOLD Stage I Chronic Obstructive Pulmonary Disease (COPD)
Recently integrated in clinical practice, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) classification states that a mild (stage I) chronic obstructive pulmonary disease (COPD) is present, in a smoker, when…
- Conditions
- Mild Chronic Obstructive Pulmonary Disease, Respiratory Symptoms, Physical Activity
- Trial name
- GOLD (NCT01360788)
- Where
- Canada
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Laval University
Fibromyalgia (FM), Chronic Pain
The Effect of Physiotherapy Integrated With Yoga and Mindfulness on Individuals With Fibromyalgia
The current study investigates the effect of an integrative physiotherapy and mind-body program called PhYoMind intervention on disability and symptoms in individuals with fibromyalgia (FM).
- Trial name
- PhYoMind (NCT07145788)
- Testing
- PhYoMind, Exercise
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Hospital Tuebingen
Hemiplegia, Cerebral Palsy
Bimanual Training in Children With Hemiplegia
A randomized control trial of bimanual training in children with hemiplegia. The protocols have been developed at Columbia University to be child friendly and draws upon our experience since 1997 with constraint-induced movement…
- Conditions
- Hemiplegia, Cerebral Palsy, Children
- Trial name
- HABIT (NCT01413594)
- Testing
- HABIT
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Teachers College, Columbia University
Interstitial Cystitis, Bladder Pain Syndrome
Assessment of Urinary Polymerase Chain Reaction (PCR) and Next Generation Sequencing (NGS) Technology in the Evaluation and Management of Females With Chronic Bladder Pain and Cystitis-like Symptoms
Real-world clinical practice multicenter study to determine the clinical implications of employing PCR/NGS technology to identify and treat potential urinary pathogens in female participants identified with bladder pain and/or…
- Trial name
- NCT05276466
- Testing
- Polymerase Chain Reaction and Next-Generation DNA Sequencing
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- MicroGenDX
Chronic Obstructive Pulmonary Disease
A Study Of ¹²⁹XE MRI To Assess Disease Progression In Patients With COPD Treated With Or Without Azithromycin And Standard-of-Care Medications
This study will test whether daily use of azithromycin will reduce the rate of exacerbations and improve lung ventilation and perfusion assessed by XE-MRI.
- Trial name
- NCT04353661
- Testing
- Azithromycin, HP xenon (¹²⁹XE)
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Genentech, Inc.
Chronic Kidney Diseases
Enhancing Physical Function in Older Adults With Chronic Kidney Disease
The goal of this pilot randomized controlled trial is to examine the feasibility and safety of a 12-week high-velocity resistance training (HVRT) intervention in older adults with chronic kidney disease (CKD) stages 4-5 and to…
- Trial name
- EPIC (NCT06738394)
- Testing
- High-Velocity Resistance Training, Attention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Wake Forest University Health Sciences
Pelvic Pain, Abdominal Pain
Female Chronic Pelvic Pain
The purpose of this study is to investigate the frequency and severity of chronic pelvic pain (CPP) in adult women living in Copenhagen Country and Zealand Country (total population 2,4 million), Denmark, in relation to selected…
- Conditions
- Pelvic Pain, Abdominal Pain, Painful Bladder Syndrome, Interstitial Cystitis
- Trial name
- Female CPP (NCT01255345)
- Testing
- Chronic pelvic pain
- Where
- Denmark
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital at Herlev
COPD, Pulmonary Disease, Chronic Obstructive
The Trajectory of Physical Activity Following Pulmonary Rehabilitation
Pulmonary rehabilitation clearly increases exercise capacity, but its effect on physical activity in the home and community settings is less clear. It may take a longer time for this increase in physical activity to occur.
- Trial name
- NCT02399254
- Where
- 4 sites in United States
- Volunteers
- 21 people
- Sponsor
- Trinity Health Of New England
Neuropathic Pain
Prediction of Inter-individual Differences in the Response to Morphine Versus Milnacipran in Patients With Sciatica
Clinical, psychophysical, behavioral or genetic factor will predict the response to opioid treatment in patients with chronic neuropathic pain.
- Trial name
- NCT01914042
- Testing
- Morphine, Milnacipran
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Rambam Health Care Campus
Genetic Alteration, Low Back Pain
Genetic Alterations From Physical Therapy in Low Back Pain and Disc Degeneration
Background and Scientific Rationale: This prospective randomized controlled trial examines the combined effect of physiotherapy and vitamin D supplementation on pain, disability, interleukin-6 (IL-6) expression, and vitamin D…
- Conditions
- Genetic Alteration, Low Back Pain, Physiotherapy
- Trial name
- Low back pain (NCT07439874)
- Testing
- Interferential therapy
- Where
- Saudi Arabia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Tabuk
Heart Failure, COPD
CREATION Health Readmission Risk Assessment Tool
This study occurs in two phases. Phase 1 involves initial item development and measurement validation of a new tool for identifying hospitalized patients at high risk for preventable readmission.
- Conditions
- Heart Failure, COPD, Myocardial Infarction, Coronary Artery Bypass Graft
- Trial name
- NCT03424382
- Where
- United States
- Volunteers
- 1,218 people
- Sponsor
- AdventHealth
Chronic Low Back Pain (CLBP)
Art Therapy for Adults With Chronic Low Back Pain
This project aims to assess the feasibility and preliminary efficacy of a supervised group-based art intervention for adults with chronic low back pain (CLBP).
- Trial name
- NCT07141069
- Testing
- Art therapy combined with Exercise, Exercise
- Where
- 2 sites in Hong Kong
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Chronic Obstructive Pulmonary Disease
Examination of Acute Effects of Different Intensity Respiratory Muscle Training on Respiratory Muscle Activations
It has been observed in the literature that respiratory muscle electromyography activations at certain threshold loads have been examined in individuals with chronic obstructive pulmonary disease.
- Trial name
- NCT04974788
- Testing
- Low Intensity Respiratory Muscle Training, Medium Intensity Respiratory Muscle Training, High Intensity Respiratory Muscle Training
- Volunteers
- 20 people
- Sponsor
- Abant Izzet Baysal University
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