Clinical trials: Chronic Disease (Physical)
Disease, Chronic
Heart Transplant Patients, Health Status and Physical Activity
The aim of this cross-sectional observational study is (1) to assess the health status of a group of heart transplant patients and their level of physical activity, (2) and to compare the health status of a group of heart…
- Trial name
- NCT05282342
- Testing
- Diagnostic tests
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Luis Santos
Polypharmacy Patients
Assessment of a Novel Algorithm System for Polypharmacy Patient Medication Safety and Consultation
The aim of this study is to determine if insights based on the analysis of historical data of multidrug patients' electronic health records, by a novel system and algorithm, is noninferior to a clinical pharmacist analysis and…
- Trial name
- NCT05589870
- Testing
- Multi-drug analysis of polypharmacy treatment
- Where
- Israel
- Volunteers
- 91 people
- Sponsor
- MDI Health
Chronic Interstitial Cystitis, Bladder Pain Syndrome
Pain Type and Interstitial Cystitis/Bladder Pain Syndrome Treatment
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a severe pain condition affecting 3-8 million people in the United States lacking treatments that work.
- Conditions
- Chronic Interstitial Cystitis, Bladder Pain Syndrome, Painful Bladder Syndrome, Cystitis, Interstitial
- Trial name
- NCT06299683
- Testing
- Psychosocial Treatment, Pelvic Floor Physical Therapy
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Vanderbilt University Medical Center
Post-viral Anosmia, Post-traumatic Anosmia
Self-assessment of Olfactory Disorders for French Speaking Patients
Sense of smell disorders are common and are said to affect up to 20% of the general population. They are often disabling and have a real impact on the quality of life.
- Conditions
- Post-viral Anosmia, Post-traumatic Anosmia, Chronic Rhinosinusitis, Idiopathic Anosmia
- Trial name
- VIF-DOR (NCT04705805)
- Testing
- Self-assessment of olfactory disorders through two questionnaires.
- Where
- France
- Volunteers
- 135 people
- Sponsor
- University Hospital, Strasbourg, France
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Acalabrutinib in Patients With Relapsed/Refractory and Treatment naïve Deletion 17p CLL/SLL
This study is to determine the response to acalabrutinib in patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).
- Trial name
- NCT02337829
- Testing
- Acalabrutinib (Arm A), Acalabrutinib (Arm B)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Acerta Pharma BV
Chronic Pain, Osteoarthritis
Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Pain Due to Osteoarthritis Taking WHO Step III Analgesics But Showing a Lack of Tolerability.
The main objective of the study is to evaluate the effectiveness, tolerability, and safety of tapentadol hydrochloride prolonged release (PR) in participants suffering from severe chronic pain due to osteoarthritis of the knee…
- Trial name
- NCT00982280
- Testing
- Tapentadol PR
- Where
- 24 sites in Australia, Denmark and 4 more
- Volunteers
- 82 people
- Sponsor
- Grünenthal GmbH
Healthy Volunteers
Assessment of Exercise Capacity in Virtual Reality
The 20th century brought a dynamic development of new technologies, including virtual reality (VR). VR is an artificial image generated by IT technologies.
- Trial name
- NCT04197024
- Testing
- Exercise capacity test, Exercise capacity test in virtual reality
- Where
- Poland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology
Pulmonary Disease, Chronic Obstructive
Assessment of Treatment With PulseHaler on Patients With Chronic Obstructive Pulmonary Disease (COPD)
The purpose of the study is to assess the safety and the effect of treatment by PulseHaler™ on patients with COPD, as measured by the change from baseline in full pulmonary functions, oxygen saturation, exercise tolerance and…
- Trial name
- NCT00821418
- Testing
- PulseHaler treatment, CPAP treatment (through a deactivated version of PulsHaler)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Respinova LTD
Obesity, Obesity, Abdominal
Impact of the Use of FeelWell™ Compression Garment on Individuals With a BMI ≥35
To assess the effect of wearing a custom-fitted, FDA-registered, Class I device, compression garment (Obesinov, S.A.R.L.) by an individual with a BMI ≥ 35 on his/her day-to-day quality of life over a period of one year.
- Conditions
- Obesity, Obesity, Abdominal, Mobility Limitation, Quality of Life
- Trial name
- NCT03798873
- Testing
- FeelWell™ Compression garment, Increase Mobility
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Feelwell Compression
Cerebral Palsy, Children
Physical, Functional and Neural Effects of Two Lower Extremity Exercise Protocols in Children With Cerebral Palsy
Background: Many people who have cerebral palsy (CP) have spastic diplegia, which affects the legs and causes difficulty with leg movement and walking.
- Conditions
- Cerebral Palsy, Children, Adolescents
- Trial name
- NCT01086670
- Testing
- Physical Exercise
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Chronic Obstructive Pulmonary Disease
SCOPE-Study: Salzburg Chronic Obstructive Pulmonary Disease- Exercise and Oxygen Study
Chronic obstructive pulmonary disease (COPD) is number four of the leading causes of death in the USA and Europe. Moreover, among the top five causes of death, this disease is the only one with increasing mortality rates.
- Trial name
- SCOPE (NCT01150383)
- Testing
- Physical exercise training with supplemental oxygen, Physical exercise training with "room air supplementation"
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Paracelsus Medical University
Copd, Asthma
Strados System at Center of Excellence
Listening to breath sounds with the stethoscope/auscultation is used by pulmonary physicians in conjunction with pulmonary function, signs and symptoms, oxygen saturation and diagnostic testing to admit, follow and discharge…
- Conditions
- Copd, Asthma, Covid19
- Trial name
- NCT04485741
- Testing
- RESP
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Strados Labs, Inc.
Chronic Obstructive Pulmonary Disease, Endothelial Dysfunction
Micro-doses of Physical Activity for COPD
Chronic obstructive pulmonary disease (COPD) is a disease of the lungs that makes it hard for people to breath. Those with COPD spend considerably more time sitting and lying and less time performing physical activity than…
- Conditions
- Chronic Obstructive Pulmonary Disease, Endothelial Dysfunction, Vascular Stiffness, Hypertension
- Trial name
- COPD (NCT05553223)
- Testing
- Microdoses of activity
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Coronary Artery Disease
Relationship Between Initial Plaque Characteristics and Stent Surface Coverage Patterns
Vulnerable plaque characterized by thin fibrous cap and large lipid core is an independent risk factor for most of acute cardiac event.
- Trial name
- NCT01024179
- Testing
- Polymer-based sirolimus-eluting stent (Partner stent )
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Harbin Medical University
Quadriplegic Cerebral Palsy, Cerebral Palsy (CP)
Intensive Bimanual Therapy Versus Conventional Physical Therapy in Quadriplegic Cerebral Palsy
Quadriplegic cerebral palsy (CP) is a severe neurological condition affecting motor control in all four limbs, often resulting in profound functional limitations in daily activities.
- Trial name
- NCT07134894
- Testing
- Intensive Bimanual Therapy plus Conventional Physical Therapy, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Lahore
COPD, Kinesiophobia Due to Dyspnea
Clinical Variables and Dyspnea and Fear of Movement in Chronic Obstructive Pulmonary Patients
Patients diagnosed with COPD who applied to the Pulmonary Diseases Department of Kırıkkale Yüksek İhtisas Hospital will be included in the study.
- Trial name
- NCT06442059
- Testing
- Kinesiophobia Level Due to Dyspnea
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Kırıkkale University
Chronic Pelvic Pain, Myofascial Trigger Point Pain
Effects of Myofascial Release and Electrical Stimulation in Chronic Pelvic Pain
Myofascial pelvic pain (MFPP) caused by myofascial trigger points (MTrPs) is a major contributor to chronic pelvic pain in women.In females,pelvic pain is the single most common indication for referral to women's health…
- Trial name
- NCT05851742
- Testing
- TENS, Myofascial trigger point release
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Chronic Inflammatory Bowel Disease
Impact of a Structured Therapeutic Education Session on the Practice of Adapted Physical Activity in Chronic Inflammatory Bowel Diseases
Chronic inflammatory bowel diseases (IBD; including Crohn's disease and ulcerative colitis) significantly impact patients' quality of life.
- Trial name
- ETAP-MICI (NCT07305454)
- Testing
- Inflammatory Bowek Disk Questionnaires, Short-International Physical Activity Questionnaries
- Where
- France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Toulouse
Chronic Disease, Fall Patients
Nature-based Therapy Program for Parkinson's Disease (PARC)
The goal of this clinical trial is to learn if a nature-based program has positive effects on the physical and psychosocial health in a group of participants with Parkinson's disease.
- Conditions
- Chronic Disease, Fall Patients, Aging Problems, Parkinson Disease
- Trial name
- PARC (NCT06452043)
- Testing
- PARC program
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- Université du Québec à Chicoutimi
Chronic Kidney Disease (CKD), CKD Stage 1-3
Multimedia Health Education on Physical Fitness and Physical Activity for Patients With Chronic Kidney Disease
This clinical trial aims to determine whether a multimedia educational intervention can effectively improve physical fitness and physical activity levels in patients with chronic kidney disease (CKD), while also evaluating its…
- Trial name
- NCT07493642
- Testing
- Multimedia Health Education, Standard Education Group
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Fu Jen Catholic University Hospital