Clinical trials: Chronic Disease (Physical)
Diabetes Mellitus, Renal Insufficiency, Chronic
Improving Health Literacy on Chronic Kidney Disease Among Diabetics: the Malaysian Nutritional, Emotional and Physical Health Literacy for Optimal Renal Outcome (My-NEPHRO) Trial
The goal of this clinical trial is to learn if a health literacy module via mobile application intervention can improve health outcomes and health literacy in diabetics with chronic kidney disease and could include any of the…
- Conditions
- Diabetes Mellitus, Renal Insufficiency, Chronic, Health Literacy, Quality of Life
- Trial name
- NCT07836556
- Testing
- Mobile application
- Volunteers
- 102 people
- Sponsor
- Universiti Sultan Zainal Abidin
Musculoskeletal Pain, Chronic Shoulder Pain
Digital Versus Conventional Physical Therapy for Chronic Shoulder Tendinopathy
This is a single-center, prospective, randomised, controlled study, with two parallel groups, designed to assess the clinical impact of a digital exercise program against conventional rehabilitation for shoulder tendonitis.
- Conditions
- Musculoskeletal Pain, Chronic Shoulder Pain, Shoulder Tendinopathy
- Trial name
- NCT04636528
- Testing
- Digital rehabilitation, Conventional rehabilitation
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Sword Health, SA
Pain
Fentanyl Transdermal Matrix Patch ZR-02-01 to Treat Chronic, Moderate to Severe Osteoarthritis (OA) Pain
The purpose of this study is to evaluate the effectiveness of the Matrix Fentanyl Patch ZR-02-01 in providing pain relief.
- Trial name
- NCT00108771
- Testing
- ZR-02-01 Fentanyl Transdermal Matrix Patch
- Where
- 13 sites in United States
- Volunteers
- 202 people
- Sponsor
- ZARS Pharma Inc.
Pulmonary Disease, Chronic Obstructive, Pulmonary Disease, Obstructive
Mortality and Symptom Burden Post Hospitalisation With COPD
Chronic Obstructive Pulmonary Disease (COPD) is a common progressive lung disease which causes breathlessness and frequent exacerbations, with patients often requiring hospitalisation.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Pulmonary Disease, Obstructive, Emphysema, Chronic Bronchitis
- Trial name
- MoSHCOPD (NCT03657121)
- Where
- 2 sites in United Kingdom
- Volunteers
- 447 people
- Sponsor
- Northumbria Healthcare NHS Foundation Trust
Chronic Kidney Disease, Hypertension
Effects of Physical Activities on the Expression of Nrf2 and Nf-kb Hemodialysis Patients
Oxidative stress and inflammation are cardiovascular risk factors in patients with chronic kidney disease (CKD) undergoing hemodialysis (HD).
- Conditions
- Chronic Kidney Disease, Hypertension, Diabetes
- Trial name
- Hemodialysis (NCT02718638)
- Testing
- physical exercises
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Phosphorus Metabolism Disorders
Dietary Phosphate and Serum Phosphorus
Overall study design is to review National Health and Nutrition Examination Survey (NHANES) data 1999-2008 for nutrition risk according to kidney function.
- Trial name
- NCT02435017
- Volunteers
- 7,895 people, healthy volunteers welcome
- Sponsor
- Linda W. Moore
Hepatitis C, Chronic
APPROACH Study: Quality of Life and Outcomes Assessment in Participants With Chronic Hepatitis C (CHC) Treated With Pegylated Interferon (PEG-IFN) Alfa-2a and Ribavirin
This multi-center, observational study will examine the clinical use and outcomes of pegylated interferon (PEG-IFN) alfa-2a and ribavirin combination (PEGASYS RBV) in participants with chronic hepatitis C (CHC).
- Trial name
- NCT02850289
- Testing
- Pegylated interferon (PEG-INF) alfa-2a, Ribavirin
- Where
- 46 sites in Canada
- Volunteers
- 385 people
- Sponsor
- Hoffmann-La Roche
Chronic Kidney Disease 5D
Intradialytic Exercise Combined With Creatine Monohydrate in Patients With Chronic Kidney Disease Undergoing Hemodialysis.
This study aims to evaluate the effects of creatine monohydrate supplementation and an intradialytic exercise program on body composition, biochemical parameters, and functional capacity in patients with chronic kidney disease…
- Trial name
- NCT07666815
- Testing
- Group A with creatine monohydrate, Group C Intradialytic Exercise Program, Comparison group D Hemodialysis
- Where
- Mexico
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Pedro Julian Flores Moreno
COPD, Diabetes
Effectiveness of Physical Exercise of Patients With Chronic Non-communicable Disease
According to the Pan American Health Organization (PAHO), chronic, non-communicable diseases (NCDs) are the main cause of death and disability in the world.
- Conditions
- COPD, Diabetes, Physical Inactivity, Frailty
- Trial name
- NCT06476015
- Testing
- Therapeutic exercise
- Where
- Colombia
- Volunteers
- 300 people
- Sponsor
- Fundacion Universitaria Maria Cano
Chronic Lymphocytic Leukemia, Exercise
Effects of a Strength Physical Exercise Program in Chronic Lymphocytic Leukemia Patients
Chronic lymphocytic leukemia (CLL) is a hematological neoplasm that primarily affects older individuals and is the most common type of leukemia in adults in Western countries.
- Trial name
- NCT06654206
- Testing
- Exercise, Home exercise
- Volunteers
- 40 people
- Sponsor
- University of Salamanca
Multiple Sclerosis, Chronic Progressive
Evidence Based Patient Information and Smartphone Accelerometry to Enhance Physical Activity in MS
Due to their ubiquitary distribution, smartphones might serve as an easy way/ possibility to use feedback mechanism in an app-based intervention program to increase physical activity in Multiple Sclerosis (MS) patients.
- Trial name
- PIA (NCT03114293)
- Testing
- Smartphone App
- Volunteers
- 40 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Chronic Obstructive Pulmonary Disease, COPD
Activity Monitor Use in COPD Patients Undergoing Rehabilitation
In patients with Chronic Obstructive Pulmonary Disease (COPD) lifestyles with lower physical activity levels have been shown to increase the risk of hospital admissions and shorten survival rates.
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD, Emphysema, Chronic Bronchitis
- Trial name
- NCT02895152
- Testing
- Feedback
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Northern Care Alliance NHS Foundation Trust
Osteoarthritis, Knee, Pain
Tapentadol (CG5503)
The purpose of this trial is to evaluate the effectiveness (level of pain control) and safety of orally administered tapentadol (CG5503) Extended Release (ER) (base) at doses of 100-250 mg twice daily in patients with moderate to…
- Trial name
- NCT00421928
- Testing
- oxycodone, tapentadol (CG5503)
- Volunteers
- 1,030 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Renal Insufficiency,Chronic, Dietary Intake Patterns
Strategies for Proactive Health in People With Kidney Function Decline
This prospective cohort study aims to investigate how kidney function decline affects multiple body systems and how personalized nutrition can help maintain health and slow disease progression.
- Conditions
- Renal Insufficiency,Chronic, Dietary Intake Patterns, Malnutrition, Frailty
- Trial name
- NCT07245186
- Where
- China
- Volunteers
- 1,800 people
- Sponsor
- Huashan Hospital
Myelodysplastic Syndrome, Myeloproliferative Neoplasms
Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders
This study will evaluate whether a geriatric assessment can lead to better treatment outcomes in older patients (age 60+) with a myeloid malignancy including acute myeloid leukemia, ,myelodysplastic syndromes, myeloproliferative…
- Conditions
- Myelodysplastic Syndrome, Myeloproliferative Neoplasms, Chronic Myelomonocytic Leukemia, Atypical Chronic Myeloid Leukemia
- Trial name
- NCT04761770
- Testing
- Geriatric assessment (GA) pre-transplant, conditioning regimen, Allogeneic CD34+ selected stem cells
- Where
- 7 sites in United States
- Volunteers
- 33 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pancreas Neoplasm, Pancreatitis
EUS Shear Wave for Solid Pancreatic Lesions.
The diagnosis of pancreas diseases is based on a combination of clinical signs, symptoms, and laboratory tests, but mainly on imaging techniques such as computed tomography (CT) and magnetic resonance (MR).
- Conditions
- Pancreas Neoplasm, Pancreatitis, Pancreatitis, Acute, Pancreatitis, Chronic
- Trial name
- NCT05095831
- Testing
- Pancreas EUS shear wave, Pancreas EUS-elastography and EUS-guided biopsy
- Where
- Ecuador
- Volunteers
- 25 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Venous Insufficiency
Physical Conditioning in Management of Chronic Venous Insufficiency
The purpose of this research is to evaluate the efficacy of a structured program of physical therapy in ameliorating the adverse consequences of Chronic Venous Insufficiency (CVI).
- Trial name
- NCT00013273
- Testing
- Physical Conditioning
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- US Department of Veterans Affairs
Chronic Pain, Schizophrenia
Assessment and Treatment for Chronic Pain in Veterans With Serious Mental Illness
Chronic pain has a highly negative impact on Veterans, especially those with serious mental illness (SMI). Chronic pain leads to poorer mental health and physical functioning, and represents a critical obstacle to rehabilitation…
- Conditions
- Chronic Pain, Schizophrenia, Psychotic Disorders, Bipolar Disorder
- Trial name
- CPSMI (NCT04118283)
- Testing
- Cognitive Behavioral Therapy for Chronic Pain, Health and Wellness
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- VA Office of Research and Development
Cerebral Palsy, Cerebral Palsy, Spastic
Photo Biostimulation and Spasticity in Cerebral Palsy
the current study will address the spasticity in calf muscle secondary to cerebral palsy in children. As the spasticity can inversely affect muscle contraction, joint function, and consequently the function and quality of life…
- Trial name
- NCT05912959
- Testing
- photo biostimulation
- Where
- Saudi Arabia
- Volunteers
- 54 people
- Sponsor
- University of Hail
Endometriosis, Chronic Pelvic Pain Syndrome
Multimodal Physiotherapy Based on Tele-rehabilitation in Chronic Pelvic Pain Associated With Endometriosis
Objective: To determine if the tele-rehabilitation program for chronic pelvic pain associated with endometriosis composed of pain education, therapeutic exercise and respiratory control decreases pain according to the Visual…
- Trial name
- NCT06209346
- Testing
- TeleRehab Group, Advices Group
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- University of Alcala
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