Clinical trials: Chronic Disease (Physical)
Migraine, Musculoskeletal Neck Pain
Effectiveness of Multimodal Physical Therapy in Migraine
INTRODUCTION: It is very common that migraine patients could refer neck pain during or after the pain phase of migraine, suggesting that migraine pathophysiological mechanisms could be effective in activating neck pain pathways…
- Conditions
- Migraine, Musculoskeletal Neck Pain, Musculoskeletal Disorder of the Neck, Chronic Migraine
- Trial name
- MIGPHYSTREAT (NCT05226559)
- Testing
- Multimodal Physical therapy approach plus usual care, Usual care
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Neuromed IRCCS
Persistent Physical Symptoms (PPS)
CBT Plus SMC Compared to SMC for Persistent Physical Symptoms in Secondary Care (PRINCE)
Brief Summary: Persistent Physical Symptoms (PPS), also known as medically unexplained symptoms (MUS) is a term used to describe a range of persistent bodily symptoms for which the exact cause is unclear.
- Trial name
- PRINCE (NCT02426788)
- Testing
- Cognitive behavioural therapy (CBT)
- Where
- 7 sites in United Kingdom
- Volunteers
- 324 people
- Sponsor
- King's College London
Cerebral Palsy, Infant Development
Neuroimaging of Babies During Natural Sleep to Assess Typical Development and Cerebral Palsy
Background: Early diagnosis of cerebral palsy (CP) is crucial, enabling intervention when neuroplasticity is at its highest. Magnetic resonance imaging (MRI) plays a vital role in CP diagnosis.
- Conditions
- Cerebral Palsy, Infant Development, Development, Infant
- Trial name
- NIBS-CP (NCT06396520)
- Testing
- No intervention, observational
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Danish Research Centre for Magnetic Resonance
Fibromyalgia
Effects of Nutritional Strategies or Manual Therapies in Women With Fibromyalgia
The study had two objectives. The first main aim was to analyze the effects of tryptophan and magnesium-enriched Mediterranean diet on psychological variables (trait anxiety, self-image, mood state, eating disorders) and sleep…
- Trial name
- NCT04158388
- Testing
- Mediterranean-diet enriched with a higher dose of tryptophan and magnesium, Isocaloric diet, Manual therapy
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- University of Alicante
Chronic Obstructive Pulmonary Disease, Pulmonary Hypertension
Non-invasive Assessment of Pulmonary Vascular Resistance in Elderly Patients With Chronic Obstructive Pulmonary Disease
Many studies have evaluated the viability of measuring the pulmonary vascular resistance (PVR) by non-invasive methods in patients with pulmonary hypertension, pulmonary thromboembolism, ischemic cardiopathy and valvular disease.
- Conditions
- Chronic Obstructive Pulmonary Disease, Pulmonary Hypertension, Cor Pulmonale
- Trial name
- PVR-COPD (NCT01554774)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Hospital Viamed Valvanera, Spain
Acute Respiratory Distress Syndrome (ARDS)
Pulmonary Overdistension Assessment With Electrical Impedance Tomography in Patients With Acute Respiratory Distress Syndrom in Prone Position.
Mechanical ventilation in COPD requires a good interaction Patient-Ventilator without asynchronies in order to reduce mortality. Dynamic hyperinflation with PEEPi is responsible for major asynchronies in COPD.
- Trial name
- Tomo-BPCO (NCT07090460)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier de la côte Basque
Kidney Disease, Chronic, Endothelial Dysfunction
The Effect of Dietary Nitrates on Physical Performance and Vascular Function in Chronic Kidney Disease
The purpose of this study is to examine the effect of acute ingestion of a concentrated beetroot juice supplement on vascular function and exercise capacity in patients with moderate to severe chronic kidney disease
- Trial name
- NCT04103736
- Testing
- Beet It Sport Shot
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Delaware
Comprehensive Geriatric Assessment, Chronic Disease Management
Comprehensive Geriatric Assessment in Chronic Disease Management for Older Adults in China: A Registry Study （CGACDM - Older Adults in China）
With the continuous development of China's economy and the improvement of medical standards, the life expectancy of the Chinese population has significantly increased.
- Conditions
- Comprehensive Geriatric Assessment, Chronic Disease Management, Older Adults (65 Years and Older)
- Trial name
- CGACDM - Older (NCT07033871)
- Testing
- comprehensive geriatric assessment
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Henan Provincial People's Hospital
Chronic Obstructive Pulmonary Disease (COPD)
Noninvasive Ventilation on Chronic Obstructive Pulmonary Disease (COPD) Patient Functionality
On the following tests, there would be a greater increase in the functionality of COPD patients who underwent combined therapy than in those who only exercised: a set of activities of daily living (ADLs), the six-minute walk test…
- Trial name
- kmarrara (NCT01464736)
- Testing
- physical training
- Where
- Brazil
- Volunteers
- 23 people
- Sponsor
- Universidade Federal de Sao Carlos
Chronic Stable Angina
Multi-slice CT Coronary Angiography in Patients With Stable Angina
early identification of vulnerable plaques by remodeling index prior to rupture and development of acute event is of considerable importance especially by a reliable non-invasive method as CT coronary angiography.
- Trial name
- NCT03963609
- Testing
- multisclice CT
- Volunteers
- 150 people
- Sponsor
- Benha University
Depression,, COPD
COPD Assessment Test Can Predict Depression
The frequency of depression in COPD patients are substantial and early detection and prevention of depression is critical. Recently, COPD assessment test (CAT) was developed and validated to assess the impact of COPD on patients'…
- Trial name
- NCT01727219
- Where
- South Korea
- Volunteers
- 600 people
- Sponsor
- Hallym University Medical Center
End Stage Renal Disease, Peritoneal Dialysis Complication
The Effect of Home Based Tele-Exercise on Peritoneal Dialysis Patients
Brief Summary: The objective of the trial is to assess the effect of synchronous home-based tele exercise on daily activity level, functional status and frailty level in Peritoneal Dialysis patients.
- Trial name
- NCT06787599
- Testing
- Home-based Tele Exercise
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Pardis Specialized Wellness Institute
End Stage Renal Disease, Hemodialysis
The Effects of Intradialytic Exercise in Hemodiafiltration Patients
Low physical activity is associated with in hemodialysis and hemodiafiltration (HDF) patients. Previous studies showed the benefits of intradialytic exercise for improvement of physical fitness and hemodialysis adequacy.
- Conditions
- End Stage Renal Disease, Hemodialysis, Sedentary Lifestyle
- Trial name
- NCT03353844
- Testing
- Intradialytic exercise
- Where
- Thailand
- Volunteers
- 12 people
- Sponsor
- Chulalongkorn University
Traumatic Brain Injury, Upper Extremity Dysfunction
TeleRehab to Restore Upper Limb Function in People With Chronic TBI
The study aims to inform the subsequent large-scale clinical trial focused on using telerehabilitation techniques and technologies to improve upper limb function and quality of life.
- Conditions
- Traumatic Brain Injury, Upper Extremity Dysfunction, Disability Physical
- Trial name
- NCT06184932
- Testing
- HAHE, Exergame
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kessler Foundation
Plaque Psoriasis
Plaque Psoriasis Efficacy and Safety With Secukinumab
To demonstrate in the patient pool of PASI 90 responders at Week 24 that secukinumab 300 mg s.c. when administered at a longer dosing interval is non-inferior to secukinumab 300 mg s.c.
- Trial name
- OPTIMISE (NCT02409667)
- Testing
- Secukinumab
- Where
- 200 sites in Austria, Belgium and 22 more
- Volunteers
- 16,487 people
- Sponsor
- Novartis Pharmaceuticals
Hepatitis C
An Observational Study of Maviret (Glecaprevir/Pibrentasvir) for Korean Chronic Hepatitis C Genotypes 1 to 6 Patients According to the Standard for Re-examination of New Drugs
Post-marketing surveillance study to evaluate the real world safety and effectiveness of Maviret (Glecaprevir/Pibrentasvir) administered under a normal, routine treatment practice by Korean patients with Chronic Hepatitis C…
- Trial name
- Maviret PMS (NCT03740230)
- Where
- 61 sites in South Korea
- Volunteers
- 3,134 people
- Sponsor
- AbbVie
Chronic Disease
Identifying the Effect and Working Mechanisms of MyPlan 2.0 in Adults With Type 2 Diabetes
The aim of this study is to investigate whether and how 'MyPlan 2.0' helps adults with type 2 diabetes to be more physically active or less sedentary.
- Trial name
- NCT03291171
- Testing
- MyPlan 2.0
- Where
- Belgium
- Volunteers
- 56 people
- Sponsor
- University Ghent
Chronic Low-back Pain (cLBP)
Pain Assessment Through Integrated Neurophysiology and Multidimensional Profiling
This observational case-control study aims to investigate the central neurophysiological mechanisms underlying non-specific chronic low back pain (CLBP) with neural mechanosensitivity, with wearable Optically Pumped Magnetometers…
- Trial name
- PAIN-MAP (NCT07846163)
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Chronic Obstructive Pulmonary Disease, Manual Soft Tissue Release
Combining Manual Soft Tissue Release and Exercise Training in COPD: the Effect on LF, EC, and CAF
The potential effects of combining manual soft tissue release and physical exercise training on lung function, exercise capacity, and cardiac autonomic function in patients with moderate and severe chronic obstructive pulmonary…
- Conditions
- Chronic Obstructive Pulmonary Disease, Manual Soft Tissue Release, Exercise Training, Lung Function
- Trial name
- NCT06389734
- Testing
- Manual soft tissue release, Myofascial release, Exercise training
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Cheng Kung University
Cardiovascular Diseases, Obesity Prevention
Team-based Learning Intervention to Prevent Risk Factors for Chronic Diseases - a Cluster Randomized Trial
Background: Chronic diseases, such as cardiovascular diseases, diabetes, and cancer, are a major global health issue. Their modifiable risk factors, including poor diet, physical inactivity, irregular sleep, tobacco use, and…
- Conditions
- Cardiovascular Diseases, Obesity Prevention, Sedentary Behaviors, Sleep Perception
- Trial name
- NCT06894134
- Testing
- Team-based learning
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
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