Clinical trials: Chronic Disease Lung
Pulmonary Disease, Chronic Obstructive, Exacerbation Copd
REal-time Data Monitoring for Shared Adaptive, Multi-domain and Personalised Prediction and Decision Making for Long-term Pulmonary Care Ecosystems (RE-SAMPLE)
The main objective of this RE-SAMPLE cohort study is to identify from a real-world data (RWD) set that will be collected, a subset of data that can be potentially used as important predictors and parameters for disease…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Exacerbation Copd, Comorbidities and Coexisting Conditions
- Trial name
- RE-SAMPLE (NCT04955080)
- Where
- Netherlands
- Volunteers
- 216 people
- Sponsor
- Medisch Spectrum Twente
Tuberculosis, Pulmonary
Atorvastatin to Reduce Inflammation After Tuberculosis Treatment Completion
This is a proof-of-concept phase IIB, double-blind, randomized, placebo-controlled trial to evaluate the safety and efficacy of 40 mg atorvastatin to reduce persistent lung inflammation after successful TB treatment completion in…
- Trial name
- StatinTB (NCT04147286)
- Testing
- Atorvastatin 40mg
- Where
- South Africa
- Volunteers
- 220 people
- Sponsor
- University of Cape Town
COVID-19 Associated Cardiac Involvement, Remodeling, Left Ventricle
Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19
Long COVID or Postacute sequelae of COVID-19 infection (PASC) are increasingly recognised complications, defined by lingering symptoms, not present prior to the infection, typically persisting for more than 4 weeks.
- Conditions
- COVID-19 Associated Cardiac Involvement, Remodeling, Left Ventricle, Remodeling, Vascular, Left Ventricular Dysfunction
- Trial name
- MYOFLAME-19 (NCT05619653)
- Testing
- Prednisolone, Losartan
- Where
- 5 sites in Austria, Germany
- Volunteers
- 279 people
- Sponsor
- Valentina Puentmann
Pulmonary Disease, Chronic Obstructive
Cardiovascular Function in COPD Patients
The objectives of the study are to explore the effect of treatment with tiotropium + olodaterol fixed dose combination (FDC) compared to fluticasone propionate + salmeterol FDC on: reversal of left ventricular diastolic…
- Trial name
- NCT03055988
- Testing
- Tiotropium, Olodaterol, Fluticasone propionate
- Where
- 10 sites in Germany
- Volunteers
- 76 people
- Sponsor
- Boehringer Ingelheim
Anemia, Iron-Deficiency, Kidney Failure, Chronic
Effect of Ferrlecit® Versus Oral Iron on Iron Deficient Chronic Kidney Disease (CKD) Patients Receiving Erythropoietic Agents
This study compares the effect of Ferrlecit® (a form of intravenous iron) to ferrous sulfate (a form of oral iron) in treating anemia and iron deficiency in chronic kidney disease patients who are receiving erythropoietic agents…
- Trial name
- NCT00224042
- Testing
- Sodium Ferric Gluconate complex in sucrose, Ferrous sulfate tablets
- Where
- 24 sites in United States, Puerto Rico
- Volunteers
- 52 people
- Sponsor
- Watson Pharmaceuticals
Chronic Obstructive Pulmonary Disease (COPD)
COPD Treatment by Transplantation of Autologous Bronchial Basal Cells
Chronic obstructive pulmonary disease (COPD) is a group of disease characterized by obstructed airflow. Usually, the lung structure is gradually impaired along with the progression of the disease.
- Trial name
- NCT05594303
- Testing
- Autologuos transplantation of bronchial basal cells
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Asthma-COPD Overlap
Efficiency of Budesonide Combined With Formoterol and Tiotropium in the Treatment of Acute Exacerbation of ACO
This study evaluates the efficiency of ICS(budesonide) combined with LABA (formoterol) and LAMA(tiotropium) in the treatment of acute exacerbation of asthma-chronic obstructive pulmonary overlap.
- Trial name
- NCT03504527
- Testing
- triple combinations, double combinations
- Volunteers
- 120 people
- Sponsor
- Huashan Hospital
Tinnitus
The Effect of Gabapentin on the Sensation and Impact of Tinnitus
This study evaluated the effectiveness of gabapentin in treating tinnitus in two populations: Tinnitus with associated acoustic trauma and tinnitus without associated acoustic trauma.
- Trial name
- NCT00257270
- Testing
- gabapentin
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tinnitus Research Consortium
COPD, Insomnia
Colorado Marijuana Users Health Cohort
In Colorado, marijuana is currently used for both recreational and medicinal purposes.To learn more about the positive and negative long term medical effects of marijuana use.
- Conditions
- COPD, Insomnia, Cannabis
- Trial name
- NCT02735954
- Testing
- Marijuana
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Jewish Health
Chronic Obstructive Lung Disease
The Pulmonary Protection Trial
The purpose of this study is to investigate whether patients with a preoperative reduced pulmonary function have a better preserved oxygenation capacity after open heart surgery, using either pulmonary perfusion or pulmoplegia…
- Trial name
- NCT01614951
- Testing
- Perfusion of the lungs, HTK Custodiol, Standard ECC
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Copd, COPD Exacerbation
Change in Breathing Pattern on Non-invasive Ventilation of COPD Patients Under Home Mechanical Ventilation
Acute exacerbation of COPD (AECOPD) worsen prognosis and quality of life of COPD patients. Telemonitoring could be a useful tool for early identification of AECOPD. Parameters that have to be monitored are not well defined.
- Trial name
- NCT03018470
- Testing
- Analysis of data from NIV built-in software
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Rouen
Chronic Obstructive Pulmonary Disease
Intra- and Inter-evaluator Reproducibility of Upper Limb Strength Measures in Patients With COPD
According to the recommendations of French and international learned societies, respiratory rehabilitation is part of the care of patients with Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- FORMES (NCT04341753)
- Testing
- pulmonary rehabilitation
- Where
- France
- Volunteers
- 57 people
- Sponsor
- University Hospital, Brest
Chronic Obstructive Pulmonary Disease (COPD)
Respiratory Rehabilitation Exercises in Older Adults With Acute Exacerbations of Chronic Obstructive Pulmonary Disease
The purpose of this randomized controlled trial was to evaluate the effects of a respiratory rehabilitation exercise training package on dyspnea, cough, exercise tolerance, and sputum expectoration of hospitalized elderly…
- Trial name
- NCT02329873
- Testing
- Respiratory rehabilitation exercise training
- Where
- Taiwan
- Volunteers
- 61 people
- Sponsor
- Chest Hospital, Ministry of Health and Welfare, Taiwan
Nutritional Support, Aerobic Exercise
Study on Pulmonary Rehabilitation for Stable Chronic Obstructive Pulmonary Disease(COPD) Patients
To compare the difference of effectiveness for stable COPD patients with poor nutritional status among three groups named health education, upper and lower limb exercises, and oral nutritional supplements.
- Conditions
- Nutritional Support, Aerobic Exercise, Respiratory Function Tests, Body Composition
- Trial name
- NCT04741373
- Testing
- oral nutritional supplements, rehabilitation exercise, health education
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Fudan University
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
International Severe CRSwNP Registry 2024-2028
The objective of the study is to collect real-life data worldwide, which already have been collected in national databases, to merge the data and the knowledge with the focus of better care for the individual patients, more…
- Trial name
- INVENT (NCT06617754)
- Testing
- Biologic drugs
- Where
- Denmark
- Volunteers
- 3,000 people
- Sponsor
- Vibeke Backer
COPD - Chronic Obstructive Pulmonary Disease, Forward Head Posture
Combined Posture Correction and Resistive Respiratory Muscles Training in COPD With FHP
Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms and airflow limitation, often exacerbated by postural abnormalities such as forward head posture (FHP).
- Trial name
- NCT07293429
- Testing
- Resistive inspiratory muscles training, Resistive expiratory muscles training:, Combined resistive inspiratory and expiratory muscles training
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Chronic Obstructive Pulmonary Disease
Six Minute Walking Test and Breath-holding
To compare the relationship between breath-hold time and the distance in a Six Minute Walking Test in chronic obstructive pulmonary disease population.
- Trial name
- NCT02235129
- Testing
- breath-holding
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Lung Diseases, Obstructive
Costs and Effects of Three Modes for Disease Management of Chronic Obstructive Pulmonary Disease in General Practice
In this randomized controlled trial, three contemporary modes for chronic obstructive pulmonary disease (COPD) management in Dutch general practices are compared for costs and effects: usual general practitioner (GP) care (at…
- Trial name
- NCT00128765
- Testing
- an integrated self-management education program, regular practice nurse review (monitoring controls), care at initiative of the patient (usual GP care)
- Where
- Netherlands
- Volunteers
- 165 people
- Sponsor
- Radboud University Medical Center
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
A Thorough QT (TQT) Study of CHF5993 pMDI in Healthy Volunteers (HV)
The purpose of this study is to evaluate the potential for cardiac repolarization, according to electrocardiographic monitoring (including QT and QTc intervals), of two dose levels of CHF5993 pMDI (beclomethasone…
- Trial name
- NCT05830071
- Testing
- CHF5993, CHF5259, Moxifloxacin 400mg
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
Chronic Liver Disease
To Study the Clinical Course and Outcomes of Non-electively Hospitalised Patients of Chronic Liver Disease (CLD) With Hepatic or Extra-hepatic Predominant Organ Failure(s) at 6 Months.
Title - To study the clinical course and outcomes of non-electively hospitalised patients of chronic liver disease (CLD) with Hepatic or Extra-hepatic predominant organ failure(s) at 6 months.
- Trial name
- NCT07270809
- Testing
- No Intervention
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.