Clinical trials: Chronic Diseases in Children
Force Measurement, Electromyography
Knee Neuromuscular Assessment in Children With Cerebral Palsy
The purpose of this study is to evaluate the reliability (intra-rater and inter-rater) of the K-Pull dynamometer and the K-Myo non-invasive electromyography sensor (assessing neuromuscular activity) in the evaluation of the lower…
- Conditions
- Force Measurement, Electromyography, Children, Cerebral Palsy
- Trial name
- NCT06667518
- Testing
- Neuromuscular Activity Assessment
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- University of Thessaly
Pain Management, Autism Spectrum Disorder (ASD)
Prospective Study to Determine the Prevalence of Signs of Central Sensitization in Adults With ASD Without Intellectual Developmental Disorders
Autism is a neurodevelopmental disorder (NDD) characterized by two key features: persistent deficits in communication and social interaction, and restricted, repetitive patterns of behavior, interests, and activities.
- Trial name
- Presca (NCT07495761)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Groupe Hospitalier Mutualiste de Grenoble
Cerebral Palsy
the Use of Smart Mobile Application in Mothers With Cerebral Palsy Children
There are studies in the literature aimed at supporting parents who care for children who have Cerebral Palsy. Among these, the study conducted on the use of mobile applications in supporting parents has attracted attention in…
- Trial name
- NCT06102317
- Testing
- nursing consultancy with smartphone support
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dr. Behcet Uz Children's Hospital
Cerebral Palsy
Training With Virtual Reality in Upper Arm Reaching of Children With Cerebral Palsy
The objective of this study was to evaluate the effects of training with Virtual Reality in the movement range of children with Cerebral Palsy spastic hemiparetic.The study protocol consisted of two days of training and 1…
- Trial name
- NCT04483388
- Testing
- Training with Virtual Reality, Conventional Training
- Volunteers
- 12 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Cerebral Palsy, Spastic
Effect of Pully System on Hemiplegic Children
Introduction Cerebral palsy (CP) is a group of sensory, motor, and postural disorders caused by non-progressive brain injury in early development.
- Trial name
- NCT06434246
- Testing
- pulley system exercise regimen, physical therapy program for CP
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Kafrelsheikh University
Cerebral Palsy (CP), Hemiplegia and Hemiparesis
Aquatic Based Exercises Versus Mirror Therapy on Hand Dexterity and Strength in Hemiplegic Child
Cerebral palsy (CP) is a neurologic disorder that affects motor function, balance, and posture, and spastic hemiplegia is found in about one-third of persons with CP and often leads to devastating upper limb disability.
- Trial name
- NCT07072416
- Testing
- Aquatic Exercise, Mirror Therapy, Designed physical therapy program.
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Alaa Noureldeen Kora
Cerebral Palsy, Muscle
How Are the Muscles Affected in Cerebral Palsy? A Study of Muscle Biopsies Taken During Orthopaedic Surgery.
Cerebral palsy (CP) is a motor disorder caused by an injury to the immature brain. Even though the brain damage does not change, children with CP will have progressively weaker, shorter and stiffer muscles that will lead to…
- Conditions
- Cerebral Palsy, Muscle, Muscle Contracture, Muscle Spasticity
- Trial name
- CPTDBiopsy (NCT05506228)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eva Ponten
Diplegic Spastic Cerebral Palsy
Comparing the Instrument-Assisted Soft Tissue Mobilization and Neurodevelopmental Therapy for Gross Motor Functions, Muscle Tone and Spasticity in Children with Spastic Diplegic Cerebral Palsy (GMFCS Levels I and II)
Cerebral palsy is a neurological condition that affects individuals worldwide, with a global burden of 0.9%. However, prevalence rates show regional variation, with high-income countries reporting rates of 0.2% and low-income…
- Trial name
- IASTM;NDT;CP (NCT06702709)
- Testing
- Instrument Assisted Soft Tissue Mobilization, Neurodevelopmental Therapy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Ziauddin University
Cerebral Palsy (CP)
Effect of a Humanoid Robot With Virtual Reality Games to Train Arm Function in Children With Cerebral Palsy - THRIVE Trial
About 60% of children with cerebral palsy (CP) have impaired arm function. Improving arm function requires hundreds of repetitions per day, which is impossible in a single clinical visit.
- Trial name
- THRIVE (NCT06881407)
- Testing
- Robot, Virtual Reality
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Georgia State University
Cerebral Palsy
Safety and Performance of Agilik in CP
The purpose of this post market study is to demonstrate the safety and performance of a powered extension assist (EA) knee ankle foot orthosis (KAFO), or EA-KAFO, in individuals with knee extension deficiency due to cerebral…
- Trial name
- Agilik (NCT05746871)
- Testing
- Agilik, standard care
- Where
- Italy
- Volunteers
- 9 people
- Sponsor
- IRCCS Eugenio Medea
Acquired Brain Injury, Cerebral Palsy
Movement Improvement After Paediatric Armeo®Spring Rehabilitation
Children with acquired and congenital brain lesions (namely, cerebral palsy, CP, and acquired brain injury, ABI) may exhibit upper limb impairment, with consequent limitations in their daily living activities.
- Trial name
- NCT03552614
- Testing
- Upper limb robot-assisted rehabilitation, physiotherapy
- Where
- Italy
- Volunteers
- 43 people
- Sponsor
- IRCCS Eugenio Medea
Pregnancy Related, Immune-mediated Diseases
Impact of In Utero Exposure to Immunomodulatory Drugs on Neonatal Immune System Development
What is this project about? This project aims to better understand how the immune system develops in babies whose mothers received immunomodulatory treatments during pregnancy.
- Trial name
- NEWbornIMMPACT (NCT07033663)
- Testing
- Monoclonal antibody
- Where
- 3 sites in Spain
- Volunteers
- 90 people
- Sponsor
- Fundació Sant Joan de Déu
Cerebral Palsy, Rehabilitation
The Effect of Tactile Deficit on Motor Function in Unilateral Cerebral Palsy
Cerebral palsy(CP) is the most common cause of disability in childhood. The motor spectrum of disorders is characterized by abnormal muscle tone, posture, and movement.
- Conditions
- Cerebral Palsy, Rehabilitation, Tactile Perception
- Trial name
- NCT05013814
- Testing
- Semmes-Weinstein monofilament test, Box and Block Test, 9-Hole Peg Test
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Marmara University
Cerebral Palsy, Neurologic Disorder
Whole-Body Vibration Therapy in the Gait of Children With Cerebral Palsy
Observation of the effect of vibration therapy on the gait of children with cerebral palsy and the analysis of their functional evolution
- Conditions
- Cerebral Palsy, Neurologic Disorder, Gait Disorders in Children, Hemiplegia
- Trial name
- NCT06314776
- Testing
- Usual physiotherapy without Whole-Body Vibration, Pre-Usual physiotherapy, Post-Usual physiotherapy
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
Pediatric Feeding Disorder, Chronic, Avoidant Restrictive Food Intake Disorder
The Use of Cyproheptadine in Pediatric Feeding Disorders
The goal of this clinical trial is to learn if Cyproheptadine, an appetite stimulant, can improve eating habits in children with Pediatric Feeding Disorders.
- Trial name
- NCT06751290
- Testing
- Cyproheptadine, Nutritional Counseling, Behavioral Counseling
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Cerebral Palsy Spastic Diplegia
Effect of Electrical Stimulation With Functional Task Training on Balance and Motor Abilities in Children With Diplegia
The aims of the study are to: 1. Investigate the combined effect of functional task training with electrical stimulation of bilateral hip abductor muscles on balance in children with diplegia. 2.
- Trial name
- NCT06234215
- Testing
- functional electrical stimulation, functional task training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Child, Only
Effects of Dynamic Surface Exercise Training in Children With Diplegic Cerebral Palsy
Data will be collected after the approval of synopsis a total of 14 children with diplegic cerebral palsy of age between 6 and 8 years of both genders with Gross Motor Function Classification System of level III and IV will be…
- Trial name
- NCT07244159
- Testing
- Dynamic surface exercise training, Standard physiotherapy Training
- Where
- Pakistan
- Volunteers
- 14 people
- Sponsor
- Riphah International University
Cerebral Palsy Spastic Diplegia
Effects of Dynamic Surface Exercise Training on Trunk Control and Gross Motor Functions in Children With Diplegic Cerebral Palsy
The purpose of this study was to determine the effect of dynamic surface exercise treatment on trunk control and gross motor abilities in children with spastic diplegic cerebral palsy.
- Trial name
- NCT05946096
- Testing
- Dynamic surface exercise training, conventional physical therapy
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Ayesha Hameed
Asthma
Extended Safety Study of Montelukast in Infants and Young Children With Chronic Asthma (0476-232)
Patients were treated with either montelukast 4 mg oral granules or usual care. Patients who completed Protocol MK0476-176-01 (NCT00943683) had the option to enroll in this study.
- Trial name
- NCT00943397
- Testing
- montelukast sodium, Comparator: Usual Care
- Volunteers
- 190 people
- Sponsor
- Organon and Co
Cerebral Palsy
Distal Rectus Femoris Transfer as a Part of Multilevel Surgery in Children With Spastic Diplegia
The purpose of this study is to evaluate the effects of an additional distal rectus femoris transfer carried out as a part of single-event multilevel surgery in children with spastic diplegic cerebral palsy.
- Trial name
- RectusTrans (NCT01381198)
- Testing
- Distal rectus femoris transfer
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Heidelberg University
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