Clinical trials: Chronic Diseases in Children
Asthma Chronic, Asthma in Children
Efficacy Of Doxophylline As A Sparing Treatment For Inhaled Corticosteroids In Mexican Children With Asthma
This study evaluated the efficacy of doxophylline as a steroid sparing treatment in Mexican children with asthma treated with medium ir high doses of inhaled corticosteroids (ICS).
- Trial name
- NCT03879590
- Testing
- Doxophylline, Budesonide
- Volunteers
- 60 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Cerebral Palsy (CP)
Effect of rESWT Session Frequency on Spasticity and Function Assessed by Sonoelastography in Children With Cerebral Palsy
Spasticity is a major contributor to functional limitations in children with cerebral palsy. Radial extracorporeal shock wave therapy (rESWT) has emerged as a non-invasive method for reducing spasticity; however, the optimal…
- Trial name
- CP-rESWT-FREQ (NCT07476690)
- Testing
- Real radial extracorporeal shock wave therapy (rESWT), Conventional physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Cerebral Palsy (CP)
Promotion of a Physically Active Lifestyle in Cerebral Palsy
There is increasing evidence that physical activity during childhood and adolescence has an important impact on health and behavior outcomes.
- Trial name
- NCT00940706
- Testing
- TreadMill, Physical activity in groups, Monitoring physical activity
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Assaf-Harofeh Medical Center
Cerebral Palsy
Effects of Core Stability Program on Abdominal Endurance in Wheelchair Bound Cerebral Palsy
This study aims to evaluate the effects of a Core Stability Program on abdominal endurance and constipation severity in wheelchair-bound children with cerebral palsy.
- Trial name
- NCT07764952
- Testing
- Core Stability Program, traditional Physiotherapy
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Cerebral Palsy, Dyskinetic
A Study to Test if TEV-50717 is Safe and Effective in Relieving Abnormal Involuntary Movements in Cerebral Palsy
Study TV50717-CNS-30081 is a 55-week study in which participants who have successfully completed the parent study (Study TV50717-CNS-30080) may be eligible to enroll in this study.
- Trial name
- NCT04200352
- Testing
- TEV-50717
- Where
- 30 sites in United States, Denmark and 7 more
- Volunteers
- 44 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Immune Thrombocytopenic Purpura, Helicobacter Pylori Infection
Helicobacter Pylori Treatment in Immune Thrombocytopenic Purpura (ITP) Patients
The purpose of this study is to determine whether eradication of Helicobacter pylori infection is effective in the improvement of platelet counts in children and adolescents with chronic ITP.
- Trial name
- NCT01730352
- Testing
- H. pylori triple therapy
- Where
- 4 sites in Brazil
- Volunteers
- 100 people
- Sponsor
- Federal University of São Paulo
Spastic Cerebral Palsy (sCP)
Cuevas Medek Exercises to Improve Postural Control and Balance in Children With Spastic Cerebral Palsy
This study aims to evaluate the effects of Cuevas Medek Exercises on postural control and balance in children with spastic cerebral palsy.
- Trial name
- NCT07403162
- Testing
- Cuevas medek exercises, Conventional Therapy
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Kidney Disease, Chronic, Pediatric Kidney Disease
Hemostatic Profiles in Pediatric CKD
This cross-sectional pilot study will examine the blood clotting patterns in children with chronic kidney disease stages 3, 4, and 5.
- Conditions
- Kidney Disease, Chronic, Pediatric Kidney Disease, Renal Insufficiency, Chronic, Blood Coagulation Disorders in Children
- Trial name
- NCT05064267
- Testing
- phlebotomy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Children's Healthcare of Atlanta
Pediatric Hypertension With or Without CKD
Efficacy, Safety and Tolerability of Multiple Doses of Valsartan in Children With Hypertension With or Without CKD
To assess efficacy, safety and tolerability of valsartan when comparing two doses of valsartan in reducing and controlling blood pressure in children with hypertension with or without CKD.
- Trial name
- NCT01617681
- Testing
- VAL489
- Where
- 27 sites in Belgium, Brazil and 7 more
- Volunteers
- 127 people
- Sponsor
- Novartis Pharmaceuticals
Cerebral Palsy, Spastic
Effects of Botulinum Toxin Injection Combined with RESWT in Lower Extremity Spasticity in Children with Cerebral Palsy
This study aimed to check and compare the effects of botulinum toxin injection combined with shock wave therapy versus botulinum toxin injection only for lower extremity spasticity in children with cerebral palsy
- Trial name
- NCT06494618
- Testing
- Radial Extracorporeal Shockwave Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Istanbul Medeniyet University
Hurler Syndrome, Fanconi Anemia
Bone Marrow Transplant With Abatacept for Non-Malignant Diseases
This is a single arm, phase I study to assess the tolerability of abatacept when combined with cyclosporine and mycophenolate mofetil as graft versus host disease prophylaxis in children undergoing unrelated hematopoietic stem…
- Conditions
- Hurler Syndrome, Fanconi Anemia, Glanzmann Thrombasthenia, Wiskott-Aldrich Syndrome
- Trial name
- NCT01917708
- Testing
- Abatacept
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Cerebral Palsy, Spastic Diplegia Cerebral Palsy
The Effect of Action Observation Therapy on Spasticity, Motor Function, and Balance in Children With Cerebral Palsy
In our randomized controlled study, which aims to investigate the contribution of Action Observation Therapy to rehabilitation by examining the effect of Action Observation Therapy on spasticity, gross motor function, balance and…
- Conditions
- Cerebral Palsy, Spastic Diplegia Cerebral Palsy, Hemiplegic Cerebral Palsy
- Trial name
- AOT-CP (NCT07247331)
- Testing
- action observation therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Suleyman Demirel University
Chronic Kidney Diseases
Effect of Strength and Conditioning Training on Functional Performance in Children With Chronic Kidney Disease
Despite the benefits of physical rehabilitation among adults and children with chronic illness, they avoid to engage in different physical activities especially pediatric population.
- Trial name
- NCT05657236
- Testing
- medical treatment, plyometric exercise
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Cerebral Palsy
Study in Children Who Have Switched to Isosource Junior Mix Formula
A Retrospective study In Children who have switched to Isosource Junior Mix formula (RICIMIX study) will review paediatric children > 12 months of age who require Isosource Junior Mix as an enteral tube feeding formula and have…
- Trial name
- NCT05020756
- Testing
- Isosource Junior Mix
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- Société des Produits Nestlé (SPN)
Child Development, Upper Motor Neurone Lesion
Validity and Reliability of the PROprioception Measurement Tool (PROMT)
This project assesses the feasibility, reliability, and validity of the PROMT in children with a UMN lesion. The study questions are: is the newly developed PROMT a feasible, reliable, and valid tool to assess lower limb…
- Conditions
- Child Development, Upper Motor Neurone Lesion, Cerebral Palsy, Proprioceptive Disorders
- Trial name
- PROMT (NCT05405881)
- Testing
- Proprioception measurement tool
- Where
- Switzerland
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Pediatric Obesity, Mental Health Wellness 1
The Family Stress Study - Chronic Stress and Child Adiposity: Testing a Bio-behavioural Model
The Family Stress Study is following families with young children in Guelph, Hamilton and surrounding areas over 3 years to understand how chronic stress impacts children's weight gain over time and how this association is…
- Trial name
- NCT05534711
- Where
- 2 sites in Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Cerebral Palsy
Telehealth-Supervised Resistance Training for Children With Cerebral Palsy
The goal of this clinical trial is to evaluate the feasibility and potential benefits of telehealth-supervised resistance training in ambulatory children aged 6 to 15 years with cerebral palsy (CP) classified as Gross Motor…
- Trial name
- NCT07061275
- Testing
- Telehealth-Supervised Resistance Training
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Hunan Normal University
Spastic Cerebral Palsy
Knee Joint Angle Affect Muscle Architecture in Children With Cerebral Palsy
To determine if there is an effect of knee joint angle on muscle architecture in children with spastic cerebral palsy
- Trial name
- NCT06481722
- Testing
- cerebral palsy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Secondary Hyperparathyroidism
A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving Hemodialysis
Assess the efficacy, safety, pharmacokinetics (PK) and pharmacodynamics (PD) of etelcalcetide in the treatment of secondary hyperparathyroidism (SHPT) in pediatric participants between ≥ 2 to < 18 years of age, with chronic…
- Trial name
- NCT03969329
- Testing
- Etelcalcetide
- Where
- 23 sites in Belgium, Czechia and 10 more
- Volunteers
- 24 people
- Sponsor
- Amgen
Suit Therapy, Dual Task Exercises
Effectiveness of Suit Therapy With Dual Task Exercises on Gross Motor Functions and Walking in Children With Diplegic Cerebral Palsy
This study aims to investigate the effect of suit therapy combined with dual-task training on gross motor performance and walking abilities in children with diplegic cerebral palsy.
- Conditions
- Suit Therapy, Dual Task Exercises, Gross Motor Functions, Walking
- Trial name
- NCT07096531
- Testing
- Suit therapy, Suit therapy + Dual-task exercises
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kafrelsheikh University
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