Clinical trials: Chronic Edema
COPD, ILD
Validation and Clinical Utility of the Lung Sliding Index (LSI) for Differentiating Pulmonary Diseases
This upcoming case-control study aims to confirm the Lung Sliding Index (LSI), a new ultrasound score that measures how well the pleura moves, in various lung diseases.
- Conditions
- COPD, ILD, Bronchiectasis, Pneumothorax
- Trial name
- NCT06983366
- Testing
- Lung Ultrasound
- Where
- Egypt
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Assiut University
Thoracentesis, Pleural Effusions, Chronic
GRAvity- Versus Wall Suction-drIven Large Volume Thoracentesis: a RAndomized Controlled Study (GRAWITAS Study)
The primary objective of this study is to compare gravity-driven versus wall suction-driven large volume therapeutic thoracentesis on the development of chest discomfort during the procedure.
- Conditions
- Thoracentesis, Pleural Effusions, Chronic, Pulmonary Edema
- Trial name
- NCT05131945
- Testing
- Standard Suction Thoracentesis, Gravity Thoracentesis
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- M.D. Anderson Cancer Center
Meniere Disease, Ménière
SPI-1005 for the Treatment of Meniere's Disease
The study is a randomized, double-blind, placebo-controlled, multi-center clinical trial (RCT) with open-label extension study (OLE), of SPI-1005 in adult subjects with definite Meniere's disease with active symptoms within three…
- Trial name
- STOPMD-3 (NCT04677972)
- Testing
- Ebselen
- Where
- 12 sites in United States
- Volunteers
- 220 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Venous Insufficiency of Leg, Venous Reflux
Efficacy of Vasculera in Prevention on Post-op Pain and Edema Following Lower Extremity Venous Treatment in the Outpatient Setting
The purpose of this study is to evaluate the effectiveness of Vasculera in reducing post procedural pain, bruising and edema in the post procedure period for patients diagnosed with C2-C5 disease requiring an intervention(s).
- Conditions
- Venous Insufficiency of Leg, Venous Reflux, Varicose Veins, Lower Extremity Edema Chronic
- Trial name
- NCT02936271
- Testing
- Vasculera
- Where
- United States
- Sponsor
- Corewell Health West
Chronic Venous Disease
Compression Aided Management of Edema in Patients With C3 Venous Disease
Objectives: To quantify the clinical improvement and quality of life between patients wearing compression stockings versus anti-embolism stockings in patients with varicose veins and limb edema.
- Trial name
- NCT00766974
- Testing
- Anti-embolism Knee High Stocking, 20-30 Knee High Compression Stocking
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- BSN Medical Inc
Inflammation
Intravitreal Ketorolac for Chronic Uveitis: A Investigational Safety Study
Intraocular delivery of ketorolac will be an effective means to treat inflammation and macular edema and prevent structural complications and vision loss in patients with uveitis who are unable to tolerate corticosteroids due to…
- Trial name
- INCITE (NCT01164085)
- Testing
- Intravitreal Ketorolac
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vanderbilt University
Edema, Hypervolemia
Diuretic Tuner Clinical Decision Support
This purpose of this study is to determine the effectiveness of a mobile phone application in helping to control body swelling in patients with kidney problems.
- Conditions
- Edema, Hypervolemia, Chronic Kidney Diseases, Nephrotic Syndrome
- Trial name
- NCT04759274
- Testing
- Diuretic Tuner
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Texas Southwestern Medical Center
Sinusitis, Chronic, Sinus Infection Chronic
Evaluation of the Efficacy of Azithromycin in Idiopathic Purulent Oedematous Sinusitis in Adults
Purulent Oedematous Sinusitis (POS) is a particular form of chronic rhinosinusitis observed in 2% of the general population. In spite of its heavy impact on the quality of life, There is no established recommendation for the…
- Trial name
- SOPAZITHRO (NCT05157685)
- Testing
- Azithromycin Oral Tablet
- Where
- 13 sites in France
- Volunteers
- 230 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
End Stage Renal Disease
A Simplified Lung Ultrasound Guided Management Protocol Of Pulmonary Congestion in Hemodialysis
Pulmonary congestion secondary to volume overload or interstitial tissue inflammation is common in chronic hemodialysis patients.
- Trial name
- NCT06296160
- Testing
- Intervention Group
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Hamad Medical Corporation
Chronic Kidney Diseases Stage 5
Dietary and Dialysate Sodium Reduction on Body Fluid Volume and Inflammatory State in Hemodialysis Patients
Objective: To evaluate the influence of dietary sodium reduction on body fluid volume and inflammatory state in hemodialysis (HD) patients. Design: Prospective controlled randomized study.
- Trial name
- NCT01458808
- Testing
- Dietary sodium restriction, Dialysate sodium concentration reduction
- Volunteers
- 59 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Decompensated Chronic Heart Failure, Heart Failure NYHA Class III
Epidemiology and Prognostic of the Acute Heart Failure
EPICAL 2 (Epidemiology and prognostic of the Acute Heart Failure) is an epidemiological, observational, prospective and multicenter study.
- Conditions
- Decompensated Chronic Heart Failure, Heart Failure NYHA Class III, Acute Pulmonary Edema, Cardiogenic Shock
- Trial name
- EPICAL2 (NCT02880358)
- Where
- France
- Volunteers
- 2,500 people
- Sponsor
- Central Hospital, Nancy, France
Diabetic Macular Edema
A Pilot Study on the Effect and Safety of Iluvien® in Chronic Diabetic Macular Edema Patients
To provide treating physicians with experience with ILUVIEN as well as monitoring its safety (and effectiveness) in a real-life chronic diabetic macular edema (DME) patients judged insufficiently responsive to available therapies.
- Trial name
- RESPOND (NCT02359526)
- Testing
- IlUVIEN
- Where
- 4 sites in Portugal
- Volunteers
- 12 people
- Sponsor
- Association for Innovation and Biomedical Research on Light and Image
Corneal Edema
EndoArt® Implantation in Subjects With Chronic Corneal Edema
The EndoArt® is intended to be used as an endothelial prosthesis in patients with chronic corneal edema.The EndoArt® (Artificial Endothelial layer) is a permanent implant, constructed of a clear, transparent, foldable…
- Trial name
- NCT05139771
- Testing
- THE ENDOART® IMPLANTATION (Artificial Endothelial layer)
- Where
- 12 sites in France, Georgia and 4 more
- Volunteers
- 52 people
- Sponsor
- Eye-yon Medical
Lower Limb Chronic Oedema
Oedema Study : Chroedem
The chroedem study is aiming to assess tissue and biomolecular components of chronic lower limb oedema (CO). The investigators working hypothesis is that according to the aetiology of CO, the proportion of oedema \& composition…
- Trial name
- CHROEDEM (NCT02914808)
- Testing
- Patients will undergo a lower limb MRI and blood tests
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Chronic Venous Insufficiency
Inspiratory Muscle Training in Chronic Venous Diseases
There is insufficient evidence of inspiratory muscle training on venous function, clinical severity, symptoms and functional capacity and quality of life in CVI patients.
- Trial name
- NCT05993650
- Testing
- Inspiratuar Muscle Training Group, Thoracic Expansion Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Izmir Democracy University
Chronic Oedema, Obesity
Prevalence of Chronic Oedema in Obese Patients
Persistent swelling (chronic oedema), e.g. of the legs, is quite a common condition, which can cause a number of problems, including infections (cellulitis) in the swollen area and ulceration.
- Trial name
- NCT03154593
- Testing
- Stage 2 - Bariatric Surgery
- Where
- United Kingdom
- Volunteers
- 78 people
- Sponsor
- University of Nottingham
Chronic Diabetic Macular Oedema Considered Insufficiently Responsive to Available Therapies
Iluvien Registry Safety Study
The study will include any patient treated with Iluvien at designated sites in European countries where marketing authorization has been granted in order to obtain broader safety and usage information.
- Trial name
- IRISS (NCT01998412)
- Where
- United States
- Volunteers
- 559 people
- Sponsor
- Alimera Sciences
Low Back Pain
The Effect of High Intensity Laser on Muscle Quality and Pain in Those With Low Back Pain
The purpose of this study is to evaluate the effects of CureWave laser on paraspinal muscle oxygenation, pressure pain thresholds, muscle edema, and quality, and perceived outcomes in patients with chronic low back pain.
- Trial name
- NCT04808492
- Testing
- CureWave High Intensity Laser
- Sponsor
- University of Central Florida
Brain Edema, Brain Tumor
XERECEPT® (hCRF) for Patients Requiring Dexamethasone to Treat Edema Associated With Brain Tumors
The purpose of this study is to compare the safety and efficacy of XERECEPT® to dexamethasone (Decadron) a common treatment for symptoms of brain swelling (edema).
- Trial name
- NCT00088166
- Testing
- hCRF
- Where
- 34 sites in United States, Canada
- Volunteers
- 200 people
- Sponsor
- Celtic Pharma Development Services
Renal Failure Chronic Requiring Hemodialysis
Effects of Intensified Sodium Management in Hemodialysis Patients
The primary aim of this study is to investigate whether intensive sodium management by dietary sodium restriction and by preventing positive sodium balance during dialysis can be successfully applied in chronic hemodialysis…
- Trial name
- NCT01015313
- Testing
- intensive sodium management
- Where
- 3 sites in United States
- Sponsor
- Renal Research Institute