Clinical trials: Chronic End Stage Renal Failure
Chronic Renal Disease
Effects of Low Protein Formula on Renal Function, Oxidative Stress and Antioxidant Capacities in CKD Patients
Chronic renal disease is now the tenth leading cause of mortality Taiwan. It is worth to study the effect of low protein formula on the retardation of failing renal function, decrease plasma homocysteine and oxidative stress and…
- Trial name
- NCT01999023
- Testing
- Low protein formula group
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taichung Veterans General Hospital
END STAGE RENAL DISEASE
ESTEROID WITHDRAWAL STUDY, SAFETY AND EFFICACY IN RENAL TRANPLANTATION
BACKGROUND: Non-steroid maintenance immunosuppression after transplantation can improve long-term lipid and hemodynamic profiles without severe acute rejection (AR) events that alter graft function or survival.
- Trial name
- ESWMEX001 (NCT02328222)
- Testing
- ESW group
- Where
- Mexico
- Volunteers
- 71 people
- Sponsor
- Unidad de Investigacion Medica en Enfermedades Renales
Renal Dialysis, Health Literacy Level
Impact of Hospital Pharmacist Intervention on Medication Management in Dialysis Patients
The goal of this clinical trial is to learn if an intervention of a hospital pharmacist could help, dialysis patients managed his treatment. In a first time, the health literacy level will be assed.
- Conditions
- Renal Dialysis, Health Literacy Level, Kidney Disease, Chronic
- Trial name
- IPhaDia (NCT06692231)
- Testing
- Pharmacist intervention
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier de Vichy
Uremic Pruritus
Using of Extra Virgin Olive Oil in Hemodialysis Patients to Improve Pruritus and Sleep Disorders
Background and Purpose: Itching is a common complication of hemodialysis patients, which can cause skin damage and affect the patient's comfort.
- Trial name
- NCT05466045
- Testing
- Olive oil application in hemodialysis patients with pruritus, Normal saline application in hemodialysis patients with pruritus
- Volunteers
- 86 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Kidney Diseases, End-Stage Kidney Disease
Major Outcomes With Personalized Dialysate TEMPerature
People with failed kidneys need an artificial kidney machine (called dialysis) to remove toxins and extra fluid from the body. Most patients receive dialysis treatments at a hospital three times a week.
- Conditions
- Kidney Diseases, End-Stage Kidney Disease, Hemodialysis
- Trial name
- MyTEMP (NCT02628366)
- Testing
- Personalized Dialysate Temperature
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
End-stage Chronic Kidney Failure
Potential Biomarkers of the Severity of Endothelial Damage in End-stage Chronic Kidney Failure
The principal objective of this study is to qualify markers of oxidative stress in inflammatory cells (monocytes) in patients with stage 3 kidney failure (diabetic or not), and patients with end-stage kidney failure (diabetic or…
- Trial name
- DIALYSOX (NCT02857556)
- Testing
- Blood sample, Retinal photography:, dialyse
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
End Stage Renal Disease, Decision Aid
A Guide to Conservative Care
This is a randomized pilot study to test the feasibility and acceptability of a patient decision aid on conservative care among older patients with advanced CKD and their close persons.
- Conditions
- End Stage Renal Disease, Decision Aid, Patient Engagement, Dialysis
- Trial name
- NCT04919941
- Testing
- A Guide to Conservative Care
- Where
- 2 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Washington
Hemodialysis, Probiotics
Effect of Probiotic and Synbiotic Administration on Nutritional Status in Hemodialysis Patients
This study aims to investigate the impact of probiotics and synbiotics on the nutritional status of patients with end-stage kidney disease (ESRD) who are undergoing hemodialysis.
- Conditions
- Hemodialysis, Probiotics, Synbiotics, Nutritional Status
- Trial name
- ProSyn-HD (NCT06891105)
- Testing
- Lactogemikan (Probiotic Supplement), Lactogemikan + Prebiotic Fiber (Synbiotic Supplement)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Renal Insufficiency, Chronic
TRK-100STP PhaseII Clinical Study -Chronic Renal Failure (Primary Glomerular Disease/Nephrosclerosis)
The purpose of this study is to determine the recommended dose of the sustained-release form of BPS (TRK-100STP low dose or high dose) in Japanese patients with CRF (Primary glomerular disease/nephrosclerosis).
- Trial name
- NCT02480751
- Testing
- Beraprost
- Volunteers
- 113 people
- Sponsor
- Toray Industries, Inc
End Stage Renal Disease, AV Fistula
Percutaneous Less Invasive AV Fistula for Vascular Access in ESRD
A prospective single-arm well-controlled study to evaluate the safety and effectiveness of a less invasive means of establishing vascular access to facilitate dialysis in patients with end stage renal disease.
- Conditions
- End Stage Renal Disease, AV Fistula, Fistula, End Stage Kidney Disease
- Trial name
- NCT02363972
- Testing
- Ellipsys Vascular Access Catheter
- Where
- 5 sites in United States
- Volunteers
- 103 people
- Sponsor
- Medtronic Endovascular
Chronic Renal Failure, Kidney Transplantation
Fluid Intake in Kidney Failure
Patients with renal impairment are usually advised to increase their fluid intake. There is currently, however, no evidence supporting this recommendation.
- Trial name
- NCT00842322
- Testing
- high fluid intake, normal fluid intake
- Where
- Austria
- Volunteers
- 76 people
- Sponsor
- Medical University of Vienna
ESRD, T-Cell Dysfunction
T Cell Dysfunction in ESRD
Patients with end-stage renal disease (ESRD) suffer from high morbidity and mortality of cardiovascular and infectious disease and increased risk of all-cause mortality which is mainly attributed to the disturbed immune response.
- Trial name
- NCT04658069
- Testing
- no specific interventions
- Volunteers
- 400 people
- Sponsor
- Shanghai Zhongshan Hospital
Chronic Renal Disease, Diabetic Foot
Relationship Between Chronic Renal Disease and Risk Stratification for Chronic Ulcer on the on the Diabetic Foot
Context and hypothesis: The prevalence of diabetes mellitus keeps going to increase, due to the ageing of the population and the high prevalence of overweight and obesity.
- Trial name
- NEPHROPOD (NCT04100551)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Montpellier
Chronic Renal Failure
Evaluation of Endothelial Dysfunction Using the "Flow Mediated Dilation" Test in a Population of Chronic Renal Failure Patients at Different Stages, and Evaluation of the Role of Antiphospholipid Antibodies
The vascular endothelium is an organ in its own right, playing, among other things, a primordial role in the control of vascular tone.
- Trial name
- NCT06347029
- Testing
- Urine sampling, Blood sampling, Flow mediated dilatation test
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Brugmann University Hospital
Hemodialysis, End Stage Kidney Disease (ESKD)
Dialysis Less Frequently in the Elderly
Many people who have kidney failure require hemodialysis treatments to stay alive. Hemodialysis is a procedure that cleans the blood of the toxins and fluids that build up when kidneys don't work.
- Trial name
- DLITE (NCT07738731)
- Testing
- Twice weekly hemodialysis, Thrice weekly hemodialysis treatment
- Where
- 11 sites in Canada
- Volunteers
- 210 people
- Sponsor
- Queen's University
Restless Legs Syndrome, End Stage Renal Disease
Effectiveness of Ropinirole and Gabapentin for the Treatment of RLS in Patients on Maintenance HD
Restless legs syndrome (RLS) is a neurologic disorder characterized by 1) an urge to move the legs, 2) uncomfortable sensations in the legs, 3) symptoms that are often worse the evening or when at rest , and 4) may be temporarily…
- Trial name
- NCT03708237
- Testing
- Ropinirole, Gabapentin
- Where
- 4 sites in Canada
- Volunteers
- 3 people
- Sponsor
- University of Alberta
End-Stage Renal Disease
Pediatric Kidney Transplant Without Calcineurin Inhibitors
The purpose of this study is to see the effect of using drugs other than calcineurin inhibitors to improve the rate of kidney transplant failure. Kidney transplantation can help children with end-stage kidney disease.
- Trial name
- NCT00023231
- Testing
- Daclizumab, Methylprednisolone/prednisone, Mycophenolate mofetil
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
End Stage Renal Disease
Post Market Study for VasQ, an External Support Implant for Arteriovenous Fistula
VasQ is an external support implant for arteriovenous fistulas created for dialysis access. This is a postmarket surveillance, prospective, multi-center, randomized, controlled, open label trial enrolling 300 patients randomized…
- Trial name
- NCT06516653
- Testing
- VasQ, Arteriovenous fistula creation for dialysis vascular access
- Where
- 13 sites in United States
- Volunteers
- 300 people
- Sponsor
- Laminate Medical Technologies
End-Stage Renal Disease; Hemodialysis
Nurse-Led Nutrition and Exercise Program for Hemodialysis Patients
This randomized controlled trial aims to evaluate the effectiveness of a nurse-led integrated nutrition and exercise intervention on improving health-related quality of life among hemodialysis patients.
- Trial name
- HD-NEX (NCT07535957)
- Testing
- Nurse-Led Integrated Nutrition and Exercise Program, Usual Hemodialysis Care
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- University of Misan
Kidney Failure, Chronic
Short Term Effects of FX Dialysers on QOL and Inflammation
Background: The new hollow fibre FX-class of dialysers (Fresenius Medical Care, Bad Homburg, Germany) features a number of technological improvements that may benefit the patient.
- Trial name
- NCT00291603
- Testing
- FX-class of dialyser
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- Sir Charles Gairdner Hospital
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