Clinical trials: Chronic Fatigue Symptoms
Stroke, Ischemic Stroke
Detecting and Predicting Post-stroke Cognitive Impairment Using the Oxford Cognitive Screen
Cognitive problems are common after a stroke and must be identified early so that rehabilitation can be initiated to improve outcome.
- Conditions
- Stroke, Ischemic Stroke, Hemorrhagic Stroke, Intracerebral, Cognitive Dysfunction
- Trial name
- OCS-PRECISE (NCT07897916)
- Where
- 2 sites in Denmark
- Volunteers
- 180 people
- Sponsor
- University of Copenhagen
Long COVID
tDCS in the Management of Post-COVID Disorders
Different physical and mental morbidities such as pain, fatigue, depressed mood and cognitive impairment can be triggered by coronavirus infection.
- Trial name
- tDCS (NCT06074848)
- Testing
- Transcranial Direct Current Stimulation (tDCS), Motor Training, Cognitive Training
- Where
- 2 sites in Brazil
- Volunteers
- 48 people
- Sponsor
- Universidade Federal de Pernambuco
Fatigue, Post-Acute COVID-19 Syndrome
Immunoadsorption vs. Sham Treatment in Post COVID-19 Patients With Chronic Fatigue Syndrome
The complex clinical symptoms of post COVID syndrome, especially chronic fatigue, pose a major challenge to patients and to the health care system and are frequently refractory to therapeutic intervention.
- Trial name
- NCT05954325
- Where
- Germany
- Volunteers
- 63 people
- Sponsor
- Hannover Medical School
Long COVID, Fatigue
Long COVID-19 Fatigue and Obstructive Sleep Apnea
Identify the relationship of obstructive sleep apnea (OSA) prevalence with post-COVID-19 fatigue that remains at least six months after acute disease
- Conditions
- Long COVID, Fatigue, Obstructive Sleep Apnea of Adult
- Trial name
- PostCoV2OSA (NCT05290350)
- Testing
- OSA
- Where
- 12 sites in Portugal
- Volunteers
- 300 people
- Sponsor
- Centro Hospitalar Universitario do Algarve
Bodily Distress Syndrome, Functional Somatic Disorder
DISTRESS Trial Functional Disorders - the DISTRESS Trial
A Diagnostic Clinic for Functional Somatic Disorders (FSD) has been set up at the outpatient diagnostic center at Regionshospitalet Silkeborg.
- Trial name
- DISTRESS (NCT06025617)
- Testing
- Diagnostic evaluation at the Diagnostic Clinic for Functional Disorders, Diagnostic as usual
- Where
- Denmark
- Volunteers
- 290 people
- Sponsor
- Regionshospitalet Silkeborg
Post-COVID ME/CFS
Hyperbaric High Pressure Oxygen Therapy in Post-COVID Syndrome and ME/CFS
The objective of this observational study is to document symptom progression in 60 patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) who undergo Hyperbaric Oxygen Therapy (HBOT) following COVID or other…
- Trial name
- NCT06118138
- Testing
- Hyperbaric oxygen therapy (HBOT)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
ME/CFS, Fibromyalgia (FM)
Whole-body Cryotherapy in Those With Chronic Fatigue: A Feasibility Study
Chronic fatiguing illnesses such as Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Fibromyalgia, and Long COVID are becoming a major global health challenge.
- Conditions
- ME/CFS, Fibromyalgia (FM), Long-COVID, Control Group
- Trial name
- NCT07874217
- Testing
- Cryotherapy
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
End-Stage Kidney Disease (ESKD)
Virtual Reality-Guided Imagery in Hemodialysis Patients ( VRGI-HD )
This randomized controlled trial aims to evaluate the effect of virtual reality guided imagery on selected health outcomes among adult patients receiving maintenance hemodialysis.
- Trial name
- NCT07867444
- Testing
- virtual reality-guided imagery (VRGI)
- Volunteers
- 80 people
- Sponsor
- Islamic University of Najaf
Chronic Pain, Fibromyalgia
Developing an Activity Pacing Framework: Feasibility and Acceptability
This study explores whether it is feasible to use a newly developed activity pacing framework to standardise how activity pacing is instructed by healthcare professionals in rehabilitation programmes for patients with chronic…
- Conditions
- Chronic Pain, Fibromyalgia, Chronic Fatigue Syndrome, Chronic Low Back Pain
- Trial name
- NCT03497585
- Testing
- Activity pacing framework
- Where
- United Kingdom
- Volunteers
- 112 people
- Sponsor
- Pennine Acute Hospitals NHS Trust
Chronic Fatigue With OSA, Chronic Fatigue Syndrome With OSA
Nasal Continuous Positive Airway Pressure (CPAP) in Chronic Fatigue and Sleep-disordered Breathing
Chronic fatigue (CF) and chronic fatigue syndrome (CFS) are disabling disorders that may be induced or aggravated by underlying sleep disturbances. The relationship between sleep quality and fatigue is still not fully elucidated.
- Trial name
- NCT01368718
- Where
- Belgium
- Volunteers
- 5 people
- Sponsor
- University Hospital, Ghent
Vestibulodynia, Temporomandibular Disorder
Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments
Vestibulodynia (VBD) is a complex chronic vulvar pain condition that impairs the psychological, physical, and sexual health of 1 in 6 reproductive aged women in the United States.
- Conditions
- Vestibulodynia, Temporomandibular Disorder, Fibromyalgia Syndrome, Irritable Bowel Syndrome
- Trial name
- NCT03844412
- Testing
- 5% lidocaine/5 mg/ml 0.02% estradiol compound cream, Nortriptyline
- Where
- 2 sites in United States
- Volunteers
- 209 people
- Sponsor
- Duke University
Copd, Fatigue
The Effect of Education and Reminder Messages on the Fatigue Level of Individuals With COPD
COPD is an important respiratory system disease that progresses with damage to the airways.Increased mucus secretion and thickening in the airways causes obstruction.This obstruction causes symptoms such as shortness of breath…
- Trial name
- NCT06286072
- Testing
- Education and message
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Sclerosis, Multiple
Can Fatigability Neuromuscular Explain Chronic Fatigue in People With Multiple Sclerosis?
Chronic fatigue is the most common and debilitating symptom in multiple sclerosis patients. This chronic fatigue affects their quality of life by decreasing their capacity to perform simple tasks of daily life.
- Trial name
- FatSEP (NCT03983720)
- Testing
- Evaluation of degree chronic fatigue., Questionnaires, Blood sample
- Where
- France
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Somatoform Disorders, Fibromyalgia
Immune Patterns in Pain Patients DSM-IV
The purpose of this study is to define subgroups of patients with somatoform disorders due to DSM-IV by immunological, psychological and genetic characterization.
- Conditions
- Somatoform Disorders, Fibromyalgia, Myofascial Pain Syndrome, Diffuse, Depression
- Trial name
- IPPPDIV (NCT01106339)
- Where
- Germany
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Long COVID, Brain Fog
Effect of Probiotic Strain Lactobacillus Paracasei PS23 on Brain Fog in People With Long COVID
The goal of this clinical trial is to test whether the intervention of probiotics supplement can improve symptoms of long covid syndrome. Participants will be given probiotics or placebo capsules for two month.
- Conditions
- Long COVID, Brain Fog, Cognitive Change
- Trial name
- COVID-19 (NCT06348212)
- Testing
- Lactobacillus paracasei PS23, microcrystalline cellulose
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Long COVID, Chronic Fatigue Syndrome
tVNS in Long COVID-19
A prior open label study has shown that transcutaneous vagus nerve stimulation [tVNS] can improve the health of some patients with postacute sequelae of SARS-CoV-2 infection (PASC), severely affected enough to also fulfill…
- Trial name
- NCT06585254
- Testing
- Transcutaneous vagus nerve stimulator
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cancer
Acupuncture for the Treatment of Chronic Post-Chemotherapy Fatigue: A Randomized, Phase III Trial
In a previous study, we found that acupuncture may decrease fatigue. The aim of this study is to determine whether acupuncture is helpful in reducing fatigue in cancer patients treated with chemotherapy.
- Trial name
- NCT00200096
- Testing
- Acupuncture and questionnaires
- Where
- 2 sites in United States
- Volunteers
- 101 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Post-COVID-19 Syndrome
Rehabilitation of Fatigue in Patients With Post-COVID-19 Syndrome
More than half of patients with post-COVID-19 syndrome experience fatigue. Rehabilitation is needed to treat this persistent symptom.
- Trial name
- COVIDATE-02 (NCT06814379)
- Testing
- Rehabilitation, Virtual reality based rehabilitation
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Universidad de Granada
Sleep Disturbance, Fatigue
Treating Disrupted Sleep in Individuals With Inflammatory Bowel Disease
The purpose of this study is to determine if either a targeted type of talk therapy (Phase I) or medication, Wellbutrin, (Phase II) improve sleep disturbance and/or fatigue in individuals with Inflammatory Bowel Disease (IBD).
- Conditions
- Sleep Disturbance, Fatigue, Inflammatory Bowel Disease
- Trial name
- NCT02162862
- Testing
- Behavioral Counseling, bupropion-SR
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Eva Szigethy