Clinical trials: Chronic Fatigue Symptoms
Multiple Sclerosis, Fatigue Syndrome, Chronic
Chronic Fatigue in Multiple Sclerosis: MS Copilot Boost Solution Compared to Standard Care
The main objective of the MS Boost study is to demonstrate the superiority of MSCopilot Boost over standard practice in reducing the impact of fatigue on Patients with Multiple Sclerosis (MS).
- Trial name
- MSBoost (NCT06386133)
- Testing
- MS Boost, Standard of care
- Volunteers
- 208 people
- Sponsor
- Ad scientiam
Fibromyalgia Syndrome, Fibromyalgia
Pain & Reward Neuromodulation of CNS Circuits
This pilot feasibility study aims to evaluate transcranial magnetic stimulation (TMS) targeting the prefrontal cortex in patients with fibromyalgia syndrome (FMS).
- Conditions
- Fibromyalgia Syndrome, Fibromyalgia, Chronic Pain and Fatigue
- Trial name
- PRANCIR (NCT07525063)
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Duke University
Fatigue Syndrome, Chronic, Healthy
Study of the Hypothalmic-Pituitary-Adrenal (HPA) Axis and Its Role in Major Depression
Major depression represents a major public health problem worldwide and in the U.S. Fifteen percent of the U.S. population has depression at some point in life (40 million individuals).
- Conditions
- Fatigue Syndrome, Chronic, Healthy, Mood Disorders
- Trial name
- NCT00001479
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Long-COVID, Brain Fog
Effect of Daily Walnut Consumption on Memory in Subjects With Long-COVID
Approximately 30% of patients experience "Long-COVID" syndrome presenting with symptoms such as cognitive difficulties ('brain fog'), fatigue, dyspnea, autonomic dysfunction, depression and anxiety, lasting beyond 12 weeks…
- Conditions
- Long-COVID, Brain Fog, Cognition, Memory
- Trial name
- NCT07429903
- Testing
- whole food - walnuts
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of California, Los Angeles
Chronic Obstructive Pulmonary Disease (COPD)
Neuromuscular Fatigue in Chronic Obstructive Pulonary Disease
Fatigue is a prevalent symptom in Chronic Obstructive Pulmonary Disease (COPD) that limits patients in their daily living activities.
- Trial name
- NEUROTIGUE (NCT04028973)
- Testing
- Single then dual task situation, Dual then single task situation
- Where
- 2 sites in France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Fatigue, End Stage Renal Disease
Fatigue in Chronic Haemodialysis Patients: an Experience Sampling Method Study
To investigate the course and diurnal change of fatigue symptoms and haemodialysis related symptoms in chronic haemodialysis patients, its relation to haemodialysis treatment and the association with other factors by implementing…
- Trial name
- FatHoM (NCT04049773)
- Testing
- haemodialysis
- Where
- 2 sites in Netherlands
- Volunteers
- 42 people
- Sponsor
- Zuyderland Medisch Centrum
Neck Pain, Cervical Pain
The Effect of Smartphone Use Duration in Patients With Chronic Mechanical Neck Pain.
PURPOSE: The purpose of this study is to investigate the effects of smartphone usage duration on neck pain and sense of position as well as Deep Cervical Flexor (DCF) fatigue in young and middle aged patients with chronic…
- Trial name
- NCT03745469
- Testing
- Smartphone
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Aliaa Rehan Youssef
Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), Adolescent
Effect of ACTIVE-Care on Cancer-Related Fatigue, Hope, and Psychological Resilience in Adolescents With Acute Lymphoblastic Leukemia
This study aimed to evaluate the effects of the ACTIVE-Care Integrated Physical Activity-Based Supportive Care Program on cancer-related fatigue, hope, and psychological resilience in adolescents with acute lymphoblastic leukemia…
- Conditions
- Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), Adolescent, Resilience, Psychological, Physical Activities
- Trial name
- NCT07882069
- Testing
- ACTIVE-Care Integrated Physical Activity-Based Supportive Care Program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Selcuk University
Myofascial Pelvic Pain
Transvaginal Electrical Stimulation for Myofascial Pelvic Pain
Myofascial Pelvic Pain (MPP) is a frequently overlooked musculoskeletal cause of chronic pelvic pain affecting 10-20% of all adult women.
- Trial name
- NCT05354869
- Testing
- Urostym, Standard care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Los Angeles
Fatigue Syndrome, Chronic, Microbial Colonization
Intestinal Microbiota and Chronic Fatigue Syndrome
Gut microbiota of 1) patients with chronic fatigue syndrome and 2) their healthy family members are analyzed. Up to 40 patients with chronic fatigue syndrome are randomized to receive either 1) a faecal transplant from a healthty…
- Trial name
- NCT04158427
- Testing
- Faecal transplantation
- Where
- Finland
- Volunteers
- 13 people
- Sponsor
- Tampere University Hospital
Bodily Distress Disorder Moderate, Bodily Distress Disorder Severe
Internet-based Treatment for Patients Suffering From Severe Functional Somatic Disorders
The aim of this multi-center, two-armed, randomized controlled trial is to assess the effect of a novel internet-based therapist-assisted treatment program "One step at a time" designed for the treatment of patients with moderate…
- Conditions
- Bodily Distress Disorder Moderate, Bodily Distress Disorder Severe, Fibromyalgia, Chronic Fatigue Syndrome
- Trial name
- OneSTEP (NCT05525598)
- Testing
- "One step at a time", "Get started"
- Where
- Denmark
- Volunteers
- 166 people
- Sponsor
- University of Aarhus
Chronic Fatigue Syndrome, Cognitive Impairments
Efficacy and Safety of Lisdexamfetamine Dimesylate in Adults With Chronic Fatigue Syndrome
Over the past decade, the Rochester Center for Behavioral Medicine (RCBM) has evaluated many patients with attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT01071044
- Testing
- Lisdexamfetamine Dimesylate
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Rochester Center for Behavioral Medicine
Multiple Sclerosis
Supported Treadmill Training for Progressive Multiple Sclerosis
This study is a pilot trial to evaluate the effects of supported treadmill walking in patients with primary progressive multiple sclerosis (MS) on functional and psychosocial outcomes.
- Trial name
- NCT01339234
- Testing
- Body-weight supported treadmill training
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Hicks, Audrey, Ph.D.
ME/CFS, CFS/ME
Multi-Center Registry for ME/CFS
The ME/CFS study (MECFS-R) aims to create a large-scale registry that provides data on epidemiology, phenotypes, and disease trajectories of and health care for ME/CFS at any age in Germany, which can be used for future clinical…
- Conditions
- ME/CFS, CFS/ME, ME/CFS Following EBV-associated Infectious Mononucleosis, ME/CFS Following COVID-19
- Trial name
- MECFS-R (NCT05778006)
- Where
- Germany
- Volunteers
- 650 people
- Sponsor
- Technical University of Munich
Long COVID, PASC Post Acute Sequelae of COVID 19
Brain Stimulation in Long COVID
Cognitive problems and severe fatigue are two frequently occurring symptoms in long COVID, also known as Post-Covid Condition or Post-Acute Sequelae of COVID-19 (PASC), and their causes are currently unknown.
- Conditions
- Long COVID, PASC Post Acute Sequelae of COVID 19, Post COVID-19 Condition (PCC)
- Trial name
- MALIBU (NCT07278206)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- Amsterdam UMC, location VUmc
Myalgic Encephalomyelitis
Effect of CoQ10 Plus Selenium Supplementation on Clinical Outcomes and Biochemical Markers in ME/CFS (CoSeME Study)
In recent years, it has been suggested that nutritional deficiencies may be of causal relevance in individuals with ME/CFS. These include deficiencies of vitamins and trace elements.
- Trial name
- CoSeME (NCT05128292)
- Testing
- CoQ10 plus Selenium
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Fatigue Symptom, Fatigue Intensity
Monitoring Fatigue In Daily Life In Adults With Cerebral Palsy or Acquired Brain Injury
The goal of this observational study is to learn about levels and patterns of fatigue in adults with cerebral palsy (CP) and acquired brain injury (ABI) in daily life.
- Conditions
- Fatigue Symptom, Fatigue Intensity, Cerebral Palsy (CP), Acquired Brain Injury Including Stroke
- Trial name
- NCT07135791
- Testing
- Real-time monitoring
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Irritable Bowel Syndrome, Fibromyalgia
Psychological Risk Factors for Functional Somatic Disorders
The objective of this study is to explore the role of neuroticism, perceived stress, and adverse life events, respectively, in the development and perpetuation of functional somatic disorders.
- Conditions
- Irritable Bowel Syndrome, Fibromyalgia, Chronic Fatigue Syndrome, Somatoform Disorders
- Trial name
- NCT05631860
- Volunteers
- 7,493 people
- Sponsor
- University of Aarhus
Fatigue, End Stage Renal Disease (ESRD)
Lipid Infusion in Dialysis Patients With Endotoxemia
The purpose of this study is to determine whether a phospholipid emulsion is effective in the treatment of chronic endotoxemia in hemodialysis patients.
- Trial name
- LIPIDOSE (NCT00506454)
- Testing
- Lipidose
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Sepsicure
Myasthenia Gravis
Integrating Art Therapy and Adapted Physical Activity: Toward Improved Quality of Life in Patients With Myasthenia Gravis
Myasthenia Gravis (MG) is a rare neuromuscular disease characterized by fluctuating muscle weakness and excessive fatigability. Although medical treatments have improved, MG continues to significantly impact patients' physical…
- Trial name
- APART-MG (NCT07125105)
- Testing
- Adapted Physical Activity Only, Adapted Physical Activity + Art Therapy
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Universite du Littoral Cote d'Opale