Clinical trials: Chronic Fatigue Symptoms
Chronic Nonspecific Low-back Pain
Effect of High-power Laser Acupuncture on Fatigue and Proprioception in Low Back Pain
To investigate the effect of high-intensity laser acupuncture on fatigue, proprioception, back pain and Pain self-efficacy in patients with chronic nonspecific low back pain (CNLBP).
- Trial name
- NCT07196709
- Testing
- high-power laser acupuncture and the exercise program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Control Condition, Pulmonary Disease (COPD), Chronic Obstructive
Acute Muscular and Vascular Responses to a Single Session of Exercise With BFR in COPD
Exercise training is a cornerstone of pulmonary rehabilitation (PR) in patients with chronic obstructive pulmonary disease (COPD). However, some patients derive limited benefits from conventional exercise programs.
- Conditions
- Control Condition, Pulmonary Disease (COPD), Chronic Obstructive, Blood Flow Restriction Training (BFRT)
- Trial name
- 2BFREE_aigu (NCT07668921)
- Testing
- Blood Flow Restriction, Standard exercise session
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble
Long Covid19
Effectiveness of Testofen Compared to Placebo on Long COVID Symptoms
This is a double blind, randomised, placebo-controlled trial to evaluate orally-dosed Testofen (a specialised extract of Trigonella foenum-graecum (Fenugreek) seed) compared to placebo on post COVID-19 symptoms in otherwise…
- Trial name
- NCT05795816
- Testing
- Testofen, Microcrystalline cellulose
- Where
- Australia
- Volunteers
- 150 people
- Sponsor
- RDC Clinical Pty Ltd
Fibromyalgia
Fibromyalgia Treatment Trial With Gabapentin and Osteopathic Manipulative Medicine
This study assesses the benefits of intervention with gabapentin, Osteopathic Manipulative Medicine or both for improvement of the symptoms of Fibromyalgia.
- Trial name
- FTTGO (NCT01107574)
- Testing
- Gabapentin, Osteopathic Manipulative Medicine, Gabapentin and Osteopathic Manipulative Medicine
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Good Samaritan Regional Medical Center, Oregon
Post-COVID-19 Syndrome, Long-COVID-19 Syndrome
Fat Oxidation Capacity in Patients With Post Covid-19 Syndrome
Post-COVID-19 Syndrome (PCS) is characterized by symptoms, including fatigue, reduced physical performance, dyspnea, cognitive impairment, and psychological distress.
- Trial name
- NCT06468722
- Testing
- Exercise-based rehabilitation
- Where
- Germany
- Volunteers
- 187 people
- Sponsor
- University of Witten/Herdecke
Long COVID
Fatigability in Long COVID-19
The overall goal of this project is to advance the understanding of underlying mechanisms impacting performance fatigability and perceived fatigability in Veterans with post-COVID-19 fatigue and explore the safety and feasibility…
- Trial name
- NCT05699538
- Testing
- Minimal-Dose Home-Based Resistance Exercise
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- VA Office of Research and Development
Cardiorespiratory Fitness, Exercise
Tele-Rehabilitative Exercise Training Program in Nurses With Long COVID
Long COVID can cause a decline in cardiorespiratory fitness, resulting in fatigue and negative impacts on individuals' quality of life (QoL), particularly in nurses who play a crucial role in public health.
- Conditions
- Cardiorespiratory Fitness, Exercise, Long COVID, Nurses
- Trial name
- NCT06840873
- Testing
- wearable device, Healthy consulation
- Where
- Taiwan
- Volunteers
- 68 people
- Sponsor
- Shang-Lin Chiang
Fibromyalgia, Chronic Widespread Pain
12-years Follow-up on 166 Female Patients With Fibromyalgia or Chronic Widespread Pain
A 12-year follow-up of 166 women with fibromyalgia (FM) or chronic widespread pain (CWP) in western Sweden. The 166 women participated in a Randomised Controlled Trial called GAU in 2004-2005, aiming to investigate the effect of…
- Trial name
- NCT02872129
- Where
- 3 sites in Sweden
- Volunteers
- 126 people
- Sponsor
- Göteborg University
Chronic Ankle Instability, CAI
Effects of Rigid and Kinesio Taping on Balance and Performance in Chronic Ankle Instability
The goal of this clinical trial is to evaluate the immediate effects of rigid subtalar sling taping, kinesio subtalar sling taping, and sham taping on balance, proprioception, ankle mobility, and functional performance in…
- Trial name
- FAST-CAI (NCT07627165)
- Testing
- Rigid Subtalar Sling Taping, Kinesio Subtalar Sling Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul Nisantasi University
COVID-19, Post-COVID-19 Syndrome
Acupressure and Qigong in Chronic Fatigue Post COVID-19.
International observational studies confirm the high incidence of post-infectious residual syndrome after infection with severe acute respiratory syndrome corona virus 2 (SARS-COV2), which can occur in 10-15% of all infected…
- Trial name
- ACUQiG (NCT05289154)
- Testing
- self- applied acupressure plus Qigong course plus advice literature, advice literature with naturopathy
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Charite University, Berlin, Germany
Chronic Obstructive Pulmonary Disease (COPD)
Progressive Muscle Relaxation and Deep Breathing Exercises in Patients With COPD
This randomized controlled trial evaluated the effects of progressive muscle relaxation and deep breathing exercises on fatigue and sleep quality in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT07773194
- Testing
- Progressive Muscle Relaxation, Deep Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Firat University
MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)
A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)
This is a parallel arm non-randomized dose-escalation, open-label basket exploratory phase 1 clinical trial where Mitochondrial encephalopathy, lactic acidosis, stroke-like episodes (MELAS) and Leber's hereditary optic…
- Trial name
- NCT06792500
- Testing
- Glycerol Tributyrate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- George Washington University
Chronic Fatigue Syndrome
The Feasibility, Acceptability and Clinical Utility of a New Remote-mobile Technology Intervention (ASARM) for CFS/ME in a Paediatric Population
This study aims to improve on the delivery of treatment for people with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME). People with CFS/ME have low energy.
- Trial name
- ASARM (NCT02082730)
- Testing
- ASARM
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Chronic Inflammation, Chronic Pain
Gulf War Illness Inflammation Reduction Trial
The primary objective of this clinical trial is to determine if treatment with an anti-inflammatory drug (delayed-release prednisone) improves the health-related quality of life (HRQOL) of veterans with Gulf War Illness (GWI).
- Conditions
- Chronic Inflammation, Chronic Pain, Fatigue, Cognitive Impairment
- Trial name
- GWIIRT (NCT02506192)
- Testing
- Modified-Release Prednisone
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Q Fever, Fatigue Syndrome, Chronic
The Qure Study: Q-fever Fatigue Syndrome - Response to Treatment
The objective of this study is to assess the efficacy of two treatment strategies for fatigue and disabilities in QFS: long term treatment with doxycycline or cognitive behavioral therapy (CBT).
- Conditions
- Q Fever, Fatigue Syndrome, Chronic, Coxiella Infection
- Trial name
- Qure (NCT01318356)
- Testing
- Cognitive behavioral therapy, Doxycycline
- Where
- Netherlands
- Volunteers
- 156 people
- Sponsor
- Radboud University Medical Center
Heart Arrest, Cardiac Arrest
An Intervention for Cardiac Arrest Survivors With Chronic Fatigue
The primary aim was to examine the feasibility of an Energy Conservation + Problem Solving Therapy (EC+PST) intervention delivered over the telephone and to evaluate the preliminary intervention effect on fatigue impact in daily…
- Conditions
- Heart Arrest, Cardiac Arrest, Fatigue
- Trial name
- CAF (NCT02864719)
- Testing
- Energy Conservation+Problem Solving Therapy
- Volunteers
- 18 people
- Sponsor
- University of Pittsburgh
Chronic Pain
Development of a Computerized Adaptive Test (CAT) for Evaluation of Sleep, Fatigue and Quality of Life in Patients With Chronic Pain
The purpose of this study is to evaluate quality of life, sleep and fadigue in patients with chronic pain using an Item-Response Theory methodology and also generating a Computer Adaptive Testing System
- Trial name
- CAT (NCT03410589)
- Testing
- Sinlge arm
- Where
- Brazil
- Volunteers
- 308 people
- Sponsor
- University of Sao Paulo
Post-COVID-19 Syndrome, Fatigue Syndrome, Chronic
REGAIN: RCT of Oxaloacetate for Fatigue in Long COVID
Following acute COVID-19, some patients develop a group of debilitating symptoms that include fatigue, orthostatic intolerance, difficulty with attention and concentration (often called "brain fog"), myalgias and disrupted sleep.
- Trial name
- NCT05840237
- Testing
- Anhydrous Enol-Oxaloacetate, a "Medical Food", White Rice Flour
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Terra Biological LLC
COVID-19
Transcranial Direct Stimulation for Persistent Fatigue Treatment Post-COVID-19
Fatigue is common and disabling in patients with post-COVID syndrome. There is no treatment available at this moment, and fatigue has important consequences.
- Trial name
- STIMULATECOVID (NCT05252481)
- Testing
- Active tDCS
- Where
- Spain
- Volunteers
- 47 people
- Sponsor
- Hospital San Carlos, Madrid
End-Stage Renal Disease Requiring Haemodialysis, Mobile Application
Evaluation of the Effectiveness of a Mobile Application Developed for Hemodialysis Patients.
This study aims to evaluate the effectiveness of a mobile health application developed for adult patients undergoing hemodialysis treatment.
- Trial name
- NCT07211100
- Testing
- Mobile Health Application
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Saglik Bilimleri Universitesi