Clinical trials: Chronic Fatigue Symptoms
Chronic Fatigue
Fatigue Reduction Diet
There are over 2 million breast cancer survivors today. Persistent cancer-related fatigue (PCRF), a state of being tired or weary, is one of the most common and distressing symptoms experienced by breast cancer (BC) survivors.
- Trial name
- FRD (NCT01902745)
- Testing
- Social Cognitive Theory
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
A 3-day Course for CFS/ME
Chronic fatigue syndrome/Myalgic encephalomyelitis (CFS/ME) can be a serious and disabling condition with a heavy symptom burden and low function. Work disability is common, and social life dramatically affected.
- Trial name
- NCT05236465
- Testing
- A 3-day course, Waiting list
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Norwegian University of Science and Technology
Fatigue Syndrome, Chronic, Epstein-Barr Virus Infections
Chronic Fatigue Following Acute Epstein-Barr Virus Infection in Adolescents
Chronic fatigue syndrome (CFS) is characterized by unexplained, disabling and long lasting fatigue, as well as pain, impaired memory, sleep difficulties and other symptoms.
- Trial name
- CEBA (NCT02335437)
- Where
- Norway
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Postacute Sequelae of Sars-CoV-2, Post-Acute COVID-19 Syndrome
Transcutaneous Electrical Nerve Stimulation (TENS) in Patients With Postacute Sequelae of Sars-CoV-2
The purpose of the pilot study is to examine acceptability and proof of concept effectiveness of a wireless TENS technology to address PASC associated FM.
- Conditions
- Postacute Sequelae of Sars-CoV-2, Post-Acute COVID-19 Syndrome, Widespread Chronic Pain, Fatigue Syndrome, Chronic
- Trial name
- NCT05200858
- Testing
- TENS - high-dose, TENS - low-dose
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Baylor College of Medicine
Ehlers-Danlos Syndrome, Hypermobile, Chronic Pain
Photobiomodulation for Chronic Pain and Fatigue in Hypermobile Ehlers-Danlos Syndrome (PBM-SEDh-01)
This study evaluates the effect of photobiomodulation (PBM) therapy using a MLS® class IV laser on chronic pain and fatigue in patients with hypermobile Ehlers-Danlos Syndrome (hEDS).
- Conditions
- Ehlers-Danlos Syndrome, Hypermobile, Chronic Pain, Fatigue Syndrome, Chronic
- Trial name
- PBM-SEDh-01 (NCT07637084)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Centre Medical ISM (Integrative Systemic Medicine)
Rhinosinusitis, Headache
Effect of Low Level Laser Therapy in Patients With Chronic Rhinosinusitis.
This study aimed to evaluate the efficacy of low-level laser therapy (LLLT) for Chronic sinusitis in a randomized, double-blind, placebo-controlled trial.
- Conditions
- Rhinosinusitis, Headache, Fatigue, CT
- Trial name
- Sinusitis (NCT05861817)
- Testing
- Laser theapy
- Where
- 2 sites in Egypt
- Volunteers
- 31 people
- Sponsor
- Cairo University
Fibromyalgia
The Impact of Omega-3 Fatty Acid Supplements on Fibromyalgia Symptoms
The purpose of this study is to find out if omega-3 fatty acid supplements are more effective than an inactive placebo at reducing pain, reducing fatigue and elevating mood in patients with fibromyalgia.
- Trial name
- NCT01352013
- Testing
- Omega-3 (oil)
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- Dr. Yoram Shir
Covid19, Fatigue Syndrome, Chronic
Use of 1-MNA to Improve Exercise Tolerance and Fatigue in Patients After COVID-19
Coronavirus disease 2019 (COVID-19) is a serious respiratory disease that results from infection with a newly discovered coronavirus (SARS-COV-2).
- Trial name
- NCT04961476
- Testing
- 1-MNA
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Michal Chudzik
Fatigue, Nausea and Vomiting
Nurse-Provided Care or Standard Care in Treating Patients With Pancreatic Cancer
RATIONALE: Meeting with a nurse to assess symptoms and quality of life may be more effective than standard care in treating patients with pancreatic cancer.
- Conditions
- Fatigue, Nausea and Vomiting, Pain, Pancreatic Cancer
- Trial name
- NCT00902733
- Testing
- medical chart review, questionnaire administration, fatigue assessment and management
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- City of Hope Medical Center
Fatigue, End Stage Kidney Disease
The Energy Conservation Education Intervention
Fatigue is the most common symptom reported by 70 - 85 % of people with end-stage kidney disease (ESKD) receiving haemodialysis (HD).
- Conditions
- Fatigue, End Stage Kidney Disease, Quality of Life
- Trial name
- NCT04360408
- Testing
- Energy conservation education intervention for people with end-stage kidney disease receiving hemodialysis
- Volunteers
- 126 people
- Sponsor
- Queensland University of Technology
Malignant Solid Neoplasm, Chronic Lymphocytic Leukemia
Wisconsin Ginseng for Decreasing Cancer Related Fatigue
This phase III trial compares the effect of Wisconsin ginseng (panax quinquefolius) to placebo in patients with cancer that suffer from significant fatigue.
- Conditions
- Malignant Solid Neoplasm, Chronic Lymphocytic Leukemia, Hematopoietic and Lymphatic System Neoplasm, Hodgkin Lymphoma
- Trial name
- NCT06395441
- Testing
- American Ginseng, Questionnaire Administration
- Where
- 15 sites in United States
- Volunteers
- 222 people
- Sponsor
- Mayo Clinic
Chronic Pain, Insomnia
Insomnia and Sleep Disturbances in Chronic Pain Patients - Relation to Physical Activity Level and Opioid Use
Pain is one of the most common causes of healthcare contact and long-term sick leave, with negative consequences on physical and mental health. Poor sleep is common in chronic pain patients.
- Conditions
- Chronic Pain, Insomnia, Exercise, Sleep
- Trial name
- NCT04649281
- Testing
- Accelerometry
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Bright Light Therapy in ME/CFS Patients
In this study patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) will receive bright light therapy through portable lamps for 2 weeks.
- Trial name
- BLTME (NCT06635928)
- Testing
- Bright light therapy
- Where
- Austria
- Volunteers
- 36 people
- Sponsor
- Medical University of Vienna
Fibromyalgia Syndrome, Fibromyalgia
Pain & Reward Neuromodulation of CNS Circuits
This pilot feasibility study aims to evaluate transcranial magnetic stimulation (TMS) targeting the prefrontal cortex in patients with fibromyalgia syndrome (FMS).
- Conditions
- Fibromyalgia Syndrome, Fibromyalgia, Chronic Pain and Fatigue
- Trial name
- PRANCIR (NCT07525063)
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Duke University
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (ICD-10 G93.3)
Investigating the Effects of Intermittent Hypoxia-Hyperoxia Treatment (IHHT) in People With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) to Improve Fatigue, Pain, and Quality of Life by Targeting Mitochondrial Dysfunction and Autonomic Nervous System Impairment
This study is testing a new treatment for people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and long-term symptoms after COVID-19.
- Trial name
- REenergizeME (NCT07317401)
- Testing
- Intermittent hypoxia-hyperoxia treatment (IHHT)
- Where
- Denmark
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Leukemia, CLL
A Pilot Study to Investigate the Effect of Cytotoxic Therapy and/or Radiotherapy on Cancer Related Sleep Disturbances in CLL and Breast Cancer Patients Experiencing Fatigue
The goal of this clinical research study is to learn if treatments to kill cancer cells including lenalidomide and/or radiation therapy can help to control symptoms such as sleep problems and fatigue in patients with chronic…
- Trial name
- NCT00792077
- Testing
- Lenalidomide
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- M.D. Anderson Cancer Center
Chronic Ankle Instability, CAI
Effects of Ankle Evertor Fatigue on Force Sense and Neuromuscular Activation in Subjects With Chronic Ankle Instability
The goal of this observational study is to investigate whether ankle evertor muscle fatigue impairs force perception and alters neuromuscular activation patterns during submaximal isometric contractions, and whether these effects…
- Trial name
- NCT07252219
- Where
- Slovenia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Prostate Cancer
Multimodal Therapy for the Treatment of Fatigue in Patients With Prostate Cancer Receiving Radiotherapy With Androgen Deprivation Therapy
The goal of this clinical research study is to learn about the effect of different combinations of exercise, supportive counseling, and methylphenidate/placebo for the treatment of fatigue in patients with prostate cancer.
- Trial name
- NCT01410942
- Testing
- Methylphenidate, Counseling Sessions, Standardized Exercise Intervention Program
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- M.D. Anderson Cancer Center
Primary Mitochondrial Disease
Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease
The primary objective of the FALCON study is to evaluate the efficacy of KL1333 on selected disease manifestations of primary mitochondrial disease (PMD) following 48 weeks of treatment.
- Trial name
- FALCON (NCT05650229)
- Testing
- KL1333
- Where
- 55 sites in United States, Australia and 9 more
- Volunteers
- 180 people
- Sponsor
- Pharming Technologies B.V.
Sleep Apnea, Obstructive, Hypertension
Epidemiology and Intervention of Obstructive Sleep Apnea Based on Community
This observational study in a real-world community was designed to perform epidemiological investigation and assess effect of CPAP intervention of obstructive sleep apnea.
- Conditions
- Sleep Apnea, Obstructive, Hypertension, Obesity, Diabetes
- Trial name
- NCT03280914
- Testing
- Auto-CPAP
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Guangdong Provincial People's Hospital