Clinical trials: Chronic Fatigue Symptoms
Fibromyalgia, Chronic Fatigue Syndrome
Motor Control in Chronic Fatigue Syndrome and Fibromyalgia
This project is a comprehensive study, with main focus on motor control, comparing patients with chronic fatigue syndrome / myalgic encephalopathy (CFS/ME) and/or fibromyalgia syndrome (FMS).
- Trial name
- NCT01686074
- Where
- Norway
- Volunteers
- 90 people
- Sponsor
- Norwegian University of Science and Technology
Rhinosinusitis, Headache
Effect of Low Level Laser Therapy in Patients With Chronic Rhinosinusitis.
This study aimed to evaluate the efficacy of low-level laser therapy (LLLT) for Chronic sinusitis in a randomized, double-blind, placebo-controlled trial.
- Conditions
- Rhinosinusitis, Headache, Fatigue, CT
- Trial name
- Sinusitis (NCT05861817)
- Testing
- Laser theapy
- Where
- 2 sites in Egypt
- Volunteers
- 31 people
- Sponsor
- Cairo University
Long COVID-19 Syndrome, Chronic Fatigue Syndrome
A Multicenter, Adaptive, Randomized, doublE-blinded, Placebo-controlled Study in Participants With Long COVID-19: The REVIVE Trial
IRB approval date 14-APR-2024 and public at https://plataformabrasil.saude.gov.br/login.jsf since IURB approval Long COVID is a multi-systemic condition comprising often severe and persistent symptoms (longer than 12 weeks) that…
- Trial name
- REVIVE (NCT06128967)
- Testing
- Fluvoxamine Maleate 100 MG, Metformin Extended Release Oral Tablet
- Where
- 6 sites in Brazil
- Volunteers
- 399 people
- Sponsor
- Cardresearch
Chronic Fatigue Syndrome
Patient-Partner Stress Management Effects on Chronic Fatigue Syndrome Symptoms and Neuroimmune Process
The purpose of this study is to test the effects of a videotelephone-delivered patient-partner dual-focused cognitive behavioral stress management intervention on chronic fatigue syndrome (CFS) symptoms and related psychosocial…
- Trial name
- NCT01650636
- Testing
- Patient-Partner Videotelephone-delivered Health Information (PP-T-HI), Patient-Partner Videotelephone-delivered Cognitive Behavioral Stress Management intervention (PP-T-CBSM)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Miami
Chronic Obstructive Pulmonary Disease (COPD)
Investigation of the Effect of Structured Energy Conservation Techniques Training on COPD Patients
Chronic obstructive pulmonary disease (COPD) is a heterogeneous lung disease characterized by chronic respiratory symptoms (dyspnea, cough, sputum production, and/or exacerbations) due to persistent, often progressive airflow…
- Trial name
- NCT07581132
- Testing
- Structured Energy Conservation Techniques Training
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Akdeniz University
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
The Effect of Acupuncture Therapy on Cognitive Function in Post-COVID-19 Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Background of study: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a common sequela after SARS-CoV-2 infection(COVID-19). Cognitive dysfunction is one of the most common debilitating symptoms in ME/CFS.
- Trial name
- NCT07357688
- Testing
- Acupuncture
- Where
- 2 sites in China
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Xi Wu
Depression, Anxiety
Whole Body Hyperthermia Registry Study
This protocol will allow for the implementation of a research registry pertaining to Whole Body Hyperthermia (WBH) use in various subject populations.
- Conditions
- Depression, Anxiety, PTSD, Fibromyalgia
- Trial name
- NCT02174003
- Testing
- High intensity whole-body infrared heating
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Multiple Sclerosis, Relapsing-Remitting, Pain, Chronic
The Effects of Relaxation Techniques on Pain, Fatigue and Kinesiophobia in Multiple Sclerosis Patients: A Three Arms Randomized Trial
Even though, current treatments including IVIG, corticosteroids, biological agents can provide positive effects on MS symptoms, MS cannot be cured completely today.
- Conditions
- Multiple Sclerosis, Relapsing-Remitting, Pain, Chronic, Fatigue Syndrome, Chronic, Kinesiophobia
- Trial name
- NCT04833673
- Testing
- PMR: Progressive Muscle Relaxation, BRT:Benson Relaxation Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hacettepe University
Persian Gulf Syndrome
Treatment Study of Carnosine Versus Placebo in Gulf War Illness (GWI)
The purpose of this study is to perform a randomized double-blind, placebo-controlled, 12 week study of the effects of carnosine on cognitive, psychometric, autonomic, and muscle strength outcomes in 100 GWI subjects.
- Trial name
- NCT00810368
- Testing
- Carnosine
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Georgetown University
Chronic Fatigue Syndrome
Exercise-related Post-exertional Malaise
This pilot study is intended to identify sex differences in myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS) during recovery from brief but high effort exercise tests.
- Trial name
- CFS/ME (NCT03331419)
- Testing
- Exercise test
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stony Brook University
Cancer-related Fatigue, Breast Cancer
Guaraná Supplementation for Cancer-Related Fatigue
Cancer-related fatigue is one of the most common and distressing symptoms experienced by patients during and after cancer treatment, and current options to manage it are limited.
- Conditions
- Cancer-related Fatigue, Breast Cancer, Lung Cancer, Colorectal Cancer
- Trial name
- GUARANA-CRF (NCT07816263)
- Testing
- Guaraná (Paullinia cupana)
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo
Chronic Pain, Central Sensitisation
Childhood Adversity, Inflammatory Reactivity and Persistent Pain
The goal of this observational study is to investigate how adverse experiences during childhood are linked to people experiencing persistent pain and fatigue in adulthood. The questions the investigators aim to answer are: 1.
- Conditions
- Chronic Pain, Central Sensitisation, Immune Response, Adverse Childhood Experiences
- Trial name
- CAIR (NCT06127693)
- Testing
- Tetravalent Influenza Vaccine, High-frequency electrical stimulation
- Where
- South Africa
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Chronic Myeloproliferative Disorders, Fatigue
American Ginseng in Treating Patients With Fatigue Caused by Cancer
RATIONALE: American ginseng may reduce fatigue in patients with cancer. It is not yet known whether American ginseng is more effective than a placebo in treating cancer-related fatigue.
- Conditions
- Chronic Myeloproliferative Disorders, Fatigue, Leukemia, Lymphoma
- Trial name
- NCT00719563
- Testing
- American ginseng
- Where
- 326 sites in United States
- Volunteers
- 364 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Chronic Obstructive Pulmonary Disease
Symptom Clusters and Immune Markers in Patients With Chronic Obstructive Pulmonary Disease (COPD) - a Longitudinal Study
COPD patients often have a wide range of physical (e.g., dyspnea, fatigue, pain) and psychological (e.g., depression, anxiety) symptoms and various other debilitating conditions that cause considerable suffering for the…
- Trial name
- SGIS (NCT01016587)
- Where
- Norway
- Volunteers
- 275 people
- Sponsor
- Oslo University Hospital
Ultramarathon Runner
Problems Associated With Ultramarathon
Acute physiological consequences of ultramarathon running are still unknown, particularly in women. Results from the investigators first studies conducted in 2009 have shown that a large part of fatigue induced by a mountain…
- Trial name
- CHAMONIX2 (NCT01602146)
- Testing
- ultramarathon running
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Long COVID, Chronic Fatigue Syndrome
Telerehabilitation for Post COVID-19 Condition
Telerehabilitation is a great alternative to offering care during a global pandemic. 85% of patients with COVID-19 report persistent symptoms up to 8 months after the infection.
- Trial name
- Telecovie (NCT05973136)
- Testing
- Telerehabilitation program based on cardiorespiratory principles
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- Université de Sherbrooke
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Bright Light Therapy in ME/CFS Patients
In this study patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) will receive bright light therapy through portable lamps for 2 weeks.
- Trial name
- BLTME (NCT06635928)
- Testing
- Bright light therapy
- Where
- Austria
- Volunteers
- 36 people
- Sponsor
- Medical University of Vienna
Myalgic Encephalomyelitis, Chronic Fatigue Syndrome
Analysis of Post-exertional Malaise Using a Two-day CPET in People With ME/CFS
This study aims to collect and identify key outcome measures or disease parameters in ME/CFS that are altered during elevated symptoms relative to baseline by gathering information before and after symptom provocation using a…
- Trial name
- NCT04026425
- Testing
- Two-day cardiopulmonary exercise test
- Where
- 3 sites in United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Ithaca College
Inflammatory Bowel Diseases, Fatigue
The Effect of a Multimodal Lifestyle Intervention on Chronic Fatigue in Patients With Inflammatory Bowel Disease
Chronic fatigue is highly prevalent in patients with conditions characterized by chronic inflammation of the gastrointestinal tract, also known as Inflammatory Bowel Disease (IBD).
- Trial name
- Multi-IBD (NCT05374967)
- Testing
- Lifestyle intervention: Live with IBD, Control group
- Where
- Netherlands
- Volunteers
- 72 people
- Sponsor
- Leiden University Medical Center
Chronic Fatigue Syndrome/ Myalgic Encephalitis (CFS/ME)
B-lymphocyte Depletion Using Rituximab in Chronic Fatigue Syndrome/ Myalgic Encephalopathy (CFS/ME). A Randomized Phase-III Study.
The hypothesis is that a subgroup of patients with Chronic Fatigue Syndrome/ Myalgic Encephalopathy (CFS/ME) have a chronically activated immune system and may benefit from B-lymphocyte treatment using the monoclonal anti-CD20…
- Trial name
- RituxME (NCT02229942)
- Testing
- Rituximab
- Where
- 5 sites in Norway
- Volunteers
- 151 people
- Sponsor
- Haukeland University Hospital