Clinical trials: Chronic Graft-versus-host-disease
Spastic Cerebral Palsy
Circuit Training in Children With Cerebral Palsy
The aim of our study is to reveal the results of circuit training to be applied to the children with Cerebral Palsy (CP) for improving their muscular strength and trunk control and also to determine their effects in terms of…
- Trial name
- NCT03529682
- Testing
- exercise, control group
- Where
- Cyprus
- Volunteers
- 62 people
- Sponsor
- Eastern Mediterranean University
Non Specific Low Back Pain
Pulse Ultrasound and Kneading Massage in Non- Specific Chronic Low Back Pain
Back pain is one of humanity most frequent complains. About nine of ten adults experience back pain at some points in their life and five out of ten working adults have back pain every year.
- Trial name
- NSCLBP (NCT03329482)
- Testing
- PULSE ULTRASOUND, KNEADING MASSAGE
- Where
- Nigeria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Obafemi Awolowo University
Chronic Kidney Disease stage3, Chronic Kidney Disease stage4
Feasibility, Safety and Efficacy of a Predominantly Plant-based Diet in an Asian Population With Chronic Kidney Disease
This two-year follow up, single-center, open-label, feasibility study will recruit outpatients from the Renal Medicine Clinic at Changi General Hospital.
- Conditions
- Chronic Kidney Disease stage3, Chronic Kidney Disease stage4, Diet Habit
- Trial name
- NCT07544524
- Testing
- Predominantly Plant-Based CKD Diet, Standard CKD Diet
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Changi General Hospital
Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Philadelphia Chromosome Positive, BCR-ABL1 Positive Chronic Myelogenous Leukemia
Dasatinib in Treating Patients With Early Chronic Phase Chronic Myelogenous Leukemia
The goal of this clinical research study is to learn if BMS-354825 (dasatinib) can help to control CML in chronic phase. The safety of this drug will also be studied.
- Trial name
- NCT00254423
- Testing
- Dasatinib
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- M.D. Anderson Cancer Center
Chronic Obstructive Pulmonary Disease
A COPD Quality Improvement Program（QIP）
QIP(Quality Improvement Programme) is a COPD quality improvement program in China. The initial step of this program is to set up the Quality Standards(QS) of COPD management in clinical practice, then embed Quality Standards into…
- Trial name
- QIP (NCT05638646)
- Testing
- Intervention group, control group
- Where
- China
- Volunteers
- 1,107 people
- Sponsor
- Shenzhen People's Hospital
Chronic Pain, Psychiatric Disorders
Adjunctive Transcranial Direct Current Stimulation
Transcranial direct current stimulation (tDCS) is an investigational device that has not been approved for the treatment of any medical condition by the FDA but is allowed to be used for research purposes.
- Trial name
- tDCS (NCT02665988)
- Testing
- tDCS
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Baylor College of Medicine
Chronic Pain
Hypnosis as a Potentiation Technique for the Interventional Treatment of Chronic Lumbar Pain
This pilot study consists in testing the efficacy of hypnosis as an adjuvant treatment for patients suffering from chronic lumbar pain and for whom a facet block is indicated by a doctor in the Centre d'antalgie of CHUV (Centre…
- Trial name
- NCT02903303
- Testing
- Hypnosis
- Where
- Switzerland
- Volunteers
- 3 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Chronic Illnesses
FAM-SOTC Intervention for Families of Children With Chronic Illnesses
Purpose: A growing number of families with children are dealing with chronic illnesses or health problems that places increased demand on the family. Nurses are in a core position to support and empower these families.
- Trial name
- NCT03901027
- Testing
- Therapeutic Conversation Interventions
- Volunteers
- 31 people
- Sponsor
- University of Iceland
Endometriosis, Chronic Pain
Internet-based ACT for Endometriosis and Chronic Pain
The primary aim of this study is to investigate the effect of Internet-delivered Acceptance and commitment therapy for endometriosis and chronic pain.
- Trial name
- NCT06153303
- Testing
- Acceptance and commitment therapy
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Skane University Hospital
Chronic Kidney Disease
Effect of Growth Hormone on Leptin, Cytokines and Body Composition of Children With Growth Failure Due to Chronic Kidney Disease
Circulating concentrations of cytokines, such as leptin, tumor necrosis factor-alpha and interleukins 1 and 6 are increased in patients with chronic kidney disease (CKD).
- Trial name
- NCT00194961
- Testing
- Recombinant Human Growth Hormone
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Weill Medical College of Cornell University
Osteopenia, Spinal Muscular Atrophy
Effects of Standing on Non-Ambulatory Children With Neuromuscular Conditions
Children with neuromuscular disabilities and limited ambulation are at significant risk for decreased bone mineral density (BMD) and increased incidence of fracture.
- Conditions
- Osteopenia, Spinal Muscular Atrophy, Cerebral Palsy, Muscular Dystrophy
- Trial name
- NCT02428673
- Testing
- Assisted Standing Treatment Program
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Gillette Children's Specialty Healthcare
Chronic Spontaneous Urticaria
Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects With Chronic Spontaneous Urticaria
Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects with Chronic Spontaneous Urticaria
- Trial name
- CALM-CSU (NCT06077773)
- Testing
- Oral EP262
- Where
- 48 sites in United States, Canada and 4 more
- Volunteers
- 113 people
- Sponsor
- Escient Pharmaceuticals, Inc
Chronic Kidney Disease
What Are the Determinations of Adult Progressive CKD? The Renal Impairment In Secondary Care (RIISC) Study
Chronic kidney disease (CKD) affects up to 16% of the adult population and is associated with significant morbidity and mortality.
- Trial name
- RIISC (NCT01722383)
- Where
- United Kingdom
- Volunteers
- 932 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
COPD
Inflammation in COPD and the Effect of Nicotinamide Riboside
The aim of this study is to investigate if nicotinamide riboside can reduce the airways inflammation associated with chronic obstructive pulmonary disease (COPD) in patients aged 60 or older.
- Trial name
- ICON (NCT04990869)
- Testing
- Nicotinamide Riboside
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
COPD
Determination of Factors Related With Daily Living Activities in Severe COPD
The main purpose of chronic obstructive pulmonary disease (COPD) rehabilitation applications is to increase the functional capacity of the patients and improve the quality of life in daily living activities (ADL).
- Trial name
- NCT04765969
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Halic University
End Stage Renal Disease
Renal Allograft Tolerance Through Mixed Chimerism
This study will examine the safety and effectiveness of a combination kidney and bone marrow transplant from a haplo-identical related donor.
- Trial name
- NCT01780454
- Testing
- MEDI-507, Rituximab, Total Body Irradiation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Massachusetts General Hospital
Mechanical Neck Pain
Deep Cervical Flexor and Sensorimotor Training for Chronic Neck Pain
This randomized controlled trial aims to investigate the effectiveness of deep cervical flexor muscle training combined with sensorimotor (proprioception) training in patients with chronic mechanical neck pain.
- Trial name
- NCT07040605
- Testing
- Deep cervical flexors muscle training and sensorimotor training, conventional physical therapy exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Neelain University
Chronic Rhinosinusitis With Nasal Polyps, Asthma; Eosinophilic
A Real-world, Head-to-head Comparison of Dupilumab Versus Mepolizumab in Danish Patients With Chronic Rhinosinusitis With Nasal Polyps
The goal of this randomized clinical trial is to compare the effects of two newly available biological drugs for the treatment of severe chronic rhinosinusitis with nasal polyps in Danish patients.
- Conditions
- Chronic Rhinosinusitis With Nasal Polyps, Asthma; Eosinophilic, Eosinophilia
- Trial name
- TORNADO (NCT05942222)
- Testing
- dupilumab, mepolizumab
- Where
- 9 sites in Denmark
- Volunteers
- 220 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Postural Tachycardia Syndrome, Chronic Orthostatic Intolerance
Objective Sleep Disturbances in Orthostatic Intolerance
We wish to study sleep architecture in patients with chronic orthostatic intolerance. We will test the null hypothesis that there is no difference in time during the various phases of sleep between patients and healthy control…
- Trial name
- NCT00581022
- Testing
- Polysomnography
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Satish R. Raj
Chronic Low Back Pain
Efficacy and Safety of Hydrocodone Bitartrate (HYD) in Subjects With Moderate to Severe Chronic Low Back Pain
The primary objective of this study is to evaluate the analgesic efficacy and safety of HYD tablets 20 to 120 mg once-daily dose compared to placebo in subjects with moderate to severe chronic low back pain uncontrolled by their…
- Trial name
- NCT01452529
- Testing
- Hydrocodone bitartrate q24h film-coated tablets
- Where
- 102 sites in United States
- Volunteers
- 905 people
- Sponsor
- Purdue Pharma LP
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