Clinical trials: Chronic Graft-versus-host-disease
Parathyroid Hormone, Tenofovir Disoproxil Fumarate
The Effects of Vitamin D and Calcium Supplementation to Parathyroid Hormone in CHB Patients Treated With TDF
Nucleot(s)ide is an antiviral drug that can reduce the number of viruses, reduce the risk of HCC, regress hepatic fibrosis and reduce death from Hepatitis B viral infection.
- Conditions
- Parathyroid Hormone, Tenofovir Disoproxil Fumarate, Chronic Hepatitis B Virus, Vitamin D
- Trial name
- TDF (NCT05313477)
- Testing
- Ergocalciferol Capsules, Calcium carbonate
- Where
- Thailand
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Pulmonary Disease, Chronic Obstructive
Acute Effects of a Stretching Program of the Rib Cage Muscles on Patients With COPD During Exercise
Investigate the effects of stretching the muscles of the rib cage in individuals with COPD during exercise.
- Trial name
- NCT02383277
- Testing
- Stretching, Control, Exercise
- Volunteers
- 20 people
- Sponsor
- Universidade Federal de Pernambuco
End-Stage Kidney Disease (ESKD), Non-valvular Atrial Fibrillation (NVAF)
The Safety and Effectiveness of Warfarin Vs Apixaban in Patients With NVAF/ VTE and ESKD on Dialysis
This is a retrospective study of End-Stage Kidney Disease (ESKD) patients on dialysis receiving apixaban or warfarin at Tawam Hospital [a tertiary care hospital in Al Ain, UAE].
- Conditions
- End-Stage Kidney Disease (ESKD), Non-valvular Atrial Fibrillation (NVAF), Venous Thromboembolism (VTE)
- Trial name
- WARD (NCT06606275)
- Testing
- Apixaban, Warfarin
- Where
- United Arab Emirates
- Volunteers
- 67 people
- Sponsor
- Abu Dhabi Health Services Company
Chronic Kidney Disease Requiring Chronic Dialysis
Smart and Fit for Kidney Transplantation
This study is a randomised controlled intervention trial for patients with chronic kidney disease who are on the waiting list for a kidney transplantation (n=200).
- Trial name
- S&F4NTx (NCT06040281)
- Testing
- intensive individual support in nutrition and exercise, Usual Care
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
COVID-19
Mechanisms Underlying Cardiovascular Consequences Associated With COVID-19 and Long COVID
AIM 1. Characterize cardiovascular phenotypes of long COVID by cardiopulmonary, meta-bolic, and cardiac mechanical/physiological responses to exercise and microvascular vasomotor function. AIM 2.
- Trial name
- NCT06427512
- Where
- United States
- Sponsor
- Columbia University
Pressure Ulcer, Foot Ulcer, Diabetic
Use of Santyl Within an Accountable Care Organization
This study is designed to assess the comparative effectiveness of SANTYL® versus standard of care in the treatment of pressure ulcers and diabetic foot ulcers within the continuum of care of an ACO.
- Trial name
- NCT02716519
- Testing
- Santyl, Standard Care
- Where
- United States
- Sponsor
- Smith & Nephew, Inc.
Anemia
FG-4592 for Treatment of Anemia in Subjects With Chronic Kidney Disease Not on Dialysis
This is a randomized, multicenter, double-blind, placebo-controlled study of the treatment of anemia in subjects with CKD not on dialysis, with treatment up to 52 weeks.
- Trial name
- NCT02652819
- Testing
- FG-4592
- Where
- 30 sites in China
- Volunteers
- 154 people
- Sponsor
- Kyntra Bio
Osteoarthritis, Knee Osteoarthritis
Pain Management In Knee Osteoarthritis
In this study, it was aimed to investigate the effect of pain management education in individuals with knee osteoarthritis with chronic pain.
- Conditions
- Osteoarthritis, Knee Osteoarthritis, Pain, Chronic
- Trial name
- NCT05844319
- Testing
- tele-education
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Istanbul University
Hepatitis C, Chronic, Drug Use
Eliminating HCV Infection Among PWUD
Identify 300 PWUD with chronic, viremic HCV infection and engage them in a multidisciplinary, generalizable model of care and initiate HCV treatment
- Trial name
- NCT05474781
- Testing
- Epclusa
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Vancouver Infectious Diseases Centre
Graft-Versus-Host Disease, GVHD
A Study of Photobiomodulation (PBM) Therapy in People With Oral Graft-Versus-Host Disease (GVHD) After Stem Cell Transplant
The purpose of this study is to find out whether photobiomodulation/PBM therapy using the Thor LX2.3 therapy system is a safe and effective treatment for oral Graft-Versus-Host Disease/GVHD.
- Conditions
- Graft-Versus-Host Disease, GVHD, Undefined
- Trial name
- NCT05675930
- Testing
- Photobiomodulation Therapy
- Where
- 9 sites in United States
- Volunteers
- 44 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Bipolar Disorder, Mood Disorders
Delivering Telemetry-Triggered Educational Content Using MyChart in Mood Disorders
Mood disorders - principally major depressive disorder and bipolar disorder - are a significant public health issue affecting one in four people during their lives in total, over 8 million Canadians are affected by mood…
- Trial name
- NCT03575728
- Testing
- MyChart-MHT
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Sunnybrook Health Sciences Centre
Cough, Bronchial Hyperreactivity
The Effect of Montelukast in Patients With Chronic Cough and Bronchial Hyperreactivity
The purpose is to determine whether montelukast during 6 weeks has superior antitussive effects (measured with the LCQ) compared with placebo in patients with cough lasting > 8 weeks and enhanced bronchial hyperreactivity.
- Trial name
- montelukast (NCT00453765)
- Testing
- montelukast
- Where
- Netherlands
- Volunteers
- 89 people
- Sponsor
- Isala
Osteoporosis, Osteoarthritis
The Effect of Exercise Training in the Community-dwelling Adults With Chronic Disorders
Previous studies have demonstrated that resistance training (RT) is beneficial to increase muscle strength, improve functional ability and the ability to rapidly produce force, known as the contractile rate of force development…
- Trial name
- NCT02017067
- Testing
- hydraulic resistance circuit training
- Where
- Taiwan
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Stroke, Acute Stroke
The Effects of Gait Rehabilitation After Stroke by Treadmill-based Robotics Versus Traditional Gait Training
This multicenter non-randomized controlled trial aims to investigate the effectiveness (an increase of the walking speed in the 10 Meter Walk Test - 10MWT) of the robotic treatment with exoskeleton or end-effector system compared…
- Conditions
- Stroke, Acute Stroke, Chronic Stroke
- Trial name
- TREAD_STROKE (NCT03688165)
- Testing
- Treadmill-based Robotic Gait Training, Traditional Over-ground Gait Training
- Where
- 4 sites in Italy
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Acute Exacerbation Chronic Obstructive Pulmonary Disease
Is it Necessary to Set External PEEP in AECOPD Patients
Acute exacerbation of chronic obstructive pulmonary disease patients with intrinsic positive end-expiratory pressure (PEEPi), Neurally adjusted ventilatory assist (NAVA) reduce work of breathing and trigger delay at any external…
- Trial name
- NCT02114567
- Testing
- PEEP titration
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Southeast University, China
Chronic Otitis Infections in pédiatric Patients
Efficacy of KNT® (KINETUBE) in Recurrent Chronic Otitis Media in Children
Otitis media are the consequence of bacterial infection. They are characterized by middle ear inflammations with a collection of fluid behind the eardrum.
- Trial name
- KINETUBE (NCT02038400)
- Testing
- KINETUBE medical Device, insertion of tympanic ventilation tubes (tympanostomy)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Non-hodgkin's Lymphoma, Follicular Lymphoma
Phase I Dose Escalation Study of IMMU-114 in Relapsed or Refractory NHL and CLL
IMMU-114 will be studied at different dose schedules and dose levels in order to assess the highest dose safely tolerated. IMMU-114 will be administered subcutaneously (under the skin).
- Conditions
- Non-hodgkin's Lymphoma, Follicular Lymphoma, Mantle Cell Lymphoma, Marginal Zone Lymphoma
- Trial name
- NCT01728207
- Testing
- IMMU-114
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Gilead Sciences
Wounds
The Use of CureXcellTM in a Community Setting for the Treatment of Hard to Heal Wounds
The primary objective of the study is to define procedures for the use of CureXcellTM in the community through Clalit Health Services.
- Trial name
- NCT01113307
- Testing
- Activated allogeneic white blood cells
- Where
- 7 sites in Israel
- Volunteers
- 131 people
- Sponsor
- Macrocure Ltd.
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
A Pilot Study on Intermittent Ibrutinib in Patients With Advanced-phase Chronic Lymphocytic Leukemia (CLL)
Ibrutinib, an inhibitor of Bruton´s tyrosine kinase (BTK) is approved in CLL as continuous, daily administration of 420 mg orally until progression.
- Trial name
- IbruOnOff (NCT04771507)
- Testing
- Ibrutinib
- Where
- 9 sites in Norway, Sweden
- Volunteers
- 50 people
- Sponsor
- Jeanette Lundin
Mastectomy, Pain, Acute
Stellate Ganglion Block for Prevention of Post Mastectomy Depression
Complications after mastectomy include chronic pain and depression.
- Conditions
- Mastectomy, Pain, Acute, Pain, Chronic
- Trial name
- SGB (NCT06263907)
- Testing
- Stellate gangalion block
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Mansoura University
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