Clinical trials: Chronic Health Condition
Chronic Chagas
Prospective Evaluation of Rapid Diagnostic Tests for Trypanosoma Cruzi Infection
Chagas disease (CD) is the most significant endemic zoonosis in Argentina. Two-thirds of affected individuals live in urban areas but only 10% globally are aware of their infection.
- Trial name
- NCT07304349
- Where
- 4 sites in Argentina
- Volunteers
- 3,234 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Parasitologia Dr. Mario Fatala Chaben
Chronic Obstructive Pulmonary Disease (COPD)
129-Xe MRI Study of Single Triple Therapy Inhaler Effects in COPD Patients With Moderate-severe Dyspnea and/or Poor Health Status With High or Low Risk of Exacerbation
The goal of this study is to study how 12-weeks daily (and optional 48-weeks) single inhaler triple therapy (fluticasone furoate (FF)-an inhaled corticosteroid; umeclidinium (UMEC)-a long-acting muscarinic antagonist; vilanterol…
- Trial name
- MUST (NCT07192016)
- Testing
- fluticasone furoate(FF)/umeclidinium (UMEC)/vilanterol(VI) (100/62.5/25) mcg
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Western University, Canada
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting
Clinnova-MS: A Prospective Cohort Study of Patients With Multiple Sclerosis (Switzerland)
This prospective cohort study is part of the Clinnova programme and aims to (i) identify clinical imaging and omics characteristics associated with early Multiple Sclerosis (MS) and with transitioning phases to progressive MS, as…
- Conditions
- Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Secondary Progressive
- Trial name
- NCT06526364
- Testing
- All participants will be asked to provide data and samples for collection and analysis.
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Basel, Switzerland
Anxiety Disorders and Symptoms, Fibromyalgia
The Benefits of Natural Medicine, Vitamin IV Therapy and Supplements: Maintaining Good Health Through Nature
Herbal Medicine is known as the medicinal use of herbal substances as a means of treating different conditions in the human body to ensure that the body remains in optimal health and wellness.
- Conditions
- Anxiety Disorders and Symptoms, Fibromyalgia, Arthritis, Chronic Pain
- Trial name
- NCT05067998
- Testing
- IV Vitamin Infused Therapy Treatment, Herbal medicine
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Faith A. Richardson
Trauma, Psychological, Personality Disorders
Strengthening the Healthy Adult Mode: a Case Experimental Study Exploring the Effects of a New Schema Therapy Protocol in an Adult Outpatient Population.
Background: Strengthening the Healthy Adult schema mode is the ultimate goal in Schema Therapy, working as an assumed mechanism of long-term change through improved positive mental health.
- Conditions
- Trauma, Psychological, Personality Disorders, Chronic Psychiatric Disorder
- Trial name
- ST-HA (NCT04466163)
- Testing
- Schema Therapy and the Healthy Adult
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Zuyderland Medisch Centrum
Fibromyalgia, Chronic Fatigue Syndrome
Effectiveness and Health Benefits of a Nutritional, Chronobiological and Physical Exercise Intervention in Fibromyalgia and Chronic Fatigue Syndrome (SYNCHRONIZE +)
Chronic pain, fatigue and insomnia are classical symptoms of Fibromyalgia and Chronic Fatigue Syndrome, affecting seriously life quality. Non-pharmacological multicomponent approach is gaining relevance in Fibromyalgia treatment.
- Trial name
- SYNCHRONIZE + (NCT05719493)
- Testing
- multicomponent treatment
- Where
- Spain
- Volunteers
- 86 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Ventricular Assist Device, Psychosocial Factors
Improved Self-management for Patients on Ventricular Assist Device (VAD) Support - Phase 3
The number of patients suffering from end-stage heart disease challenges healthcare services in the western world, where an estimated 1-2% of the population suffer from this chronic condition.
- Conditions
- Ventricular Assist Device, Psychosocial Factors, Self-management
- Trial name
- SELMA (NCT04526964)
- Testing
- Self-management curriculum
- Where
- 4 sites in Germany
- Volunteers
- 140 people
- Sponsor
- University of Freiburg
COPD, Asthma
Video-based Teach-to-goal Intervention on Inhaler Technique on Jordanian Adults With Asthma and COPD
This study was an interventional educational study that was intended to find out the effect of a video based inhaler technique education on improving inhaler technique mastery, disease control, medication adherence and patient…
- Conditions
- COPD, Asthma, Inhaled Steroid Dependent Asthma
- Trial name
- NCT05664347
- Testing
- Verbal teach to goal education, Video based teach to goal education
- Where
- Jordan
- Volunteers
- 154 people
- Sponsor
- University of Jordan
COVID-19
Impact of Long COVID-19 on the Health and Quality of Life of Military Personnel (Active or Retired) and Their Families
Severe and sometimes irreversible sequelae are observed in people who have developed a severe form of COVID-19 (pulmonary, cardiovascular, renal, neurological sequelae among others).
- Trial name
- IMP@LA (NCT05200832)
- Testing
- Online questionnaire, Semi-structured interview
- Where
- France
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Breast Cancer Female, Survivorship
Changing Health Behaviors to Manage Chronic Conditions in Community-dwelling African American Breast Cancer Survivors
The purpose of this project was to test the efficacy of partnering with a community-led wellness program to reduce disease risk and increase wellness among breast cancer survivors.
- Trial name
- NCT03575624
- Testing
- Nutritional and goal-setting education, yoga
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Mount Mary University
Chronic Disease
Improving Advance Care Planning by Preparing Diverse Seniors for Decision Making
The objective of this proposal is to test whether a multi-media website (www.prepareforyourcare.org) that is focused on preparing older adults for communication and medical decision making can help people engage in advance care…
- Trial name
- PREPARE (NCT01990235)
- Testing
- PREPARE Intervention
- Where
- United States
- Volunteers
- 541 people
- Sponsor
- University of California, San Francisco
Disability or Chronic Disease Leading to Disablement
The Impact of Outdoor Sports Practice on the Well-Being of Disabled People
Survey of the members of the French Handisports Federation (FFH) practicing outdoor sports.
- Trial name
- NCT06040450
- Testing
- Questionnaire survey
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Institut de Sante Parasport Connecte Synergies
Cancer Survivors
Comparing Multicomponent and Aerobic Training: Impact on Fitness, Psychological and Quality of Life Parameters in Cancer Survivors Patients
The goal of this clinical trial is to evaluate if a multicomponent training program (MCT), including aerobic and resistance exercises, or an aerobic training program (AT) can improve physiological, physical fitness, mental…
- Trial name
- NCT06853613
- Testing
- Multicomponent Training Protocol, Aerobic Training Protocol
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Bari Aldo Moro
Chronic Heart Failure, Cardiovascular Diseases
AI-Based Monitoring System for Chronic Heart Failure With Advanced Wearable and Mini-Invasive Devices
The goal of this observational, multicenter study is to evaluate whether AI-driven remote monitoring using a mini-invasive wearable device can improve clinical outcomes in adult patients (≥18 years) with chronic heart failure…
- Conditions
- Chronic Heart Failure, Cardiovascular Diseases, Heart Failure With Reduced Ejection Fraction (HFrEF), Heart Failure With Preserved Ejection Fraction (HFPEF)
- Trial name
- SMART-CARE (NCT06909682)
- Testing
- Intervention Group (Device Group - AI-Based Remote Monitoring), Standard Clinical Follow-Up
- Where
- Italy
- Volunteers
- 205 people
- Sponsor
- University of Salerno
Type 2 Diabetes, Diabetes Mellitus, Type 2
The Effectiveness of Using a Mobile Application for Type 2 Diabetes Self-care
The purpose of the research is to evaluate and test the usefulness of the mobile application forDiabetes to improve the self-care of individuals with diabetes type 1.
- Conditions
- Type 2 Diabetes, Diabetes Mellitus, Type 2, Disease, Chronic, Self-Care
- Trial name
- NCT04999189
- Testing
- Mobile app forDiabetes (Tessera Multimedia, 2020)
- Volunteers
- 380 people
- Sponsor
- University Maribor
Chronic Obstructive Pulmonary Disease, Balance
Investigation of Impairments in Body Functions and Structures, Activities and Participation Restrictions in COPD
This cross-sectional study aims to investigate to the impairments in body functions and structures, activities and participation restrictions according to the International Classification of Functioning, Disability and Health…
- Conditions
- Chronic Obstructive Pulmonary Disease, Balance, Activity, Motor, Participation, Patient
- Trial name
- NCT05632120
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Smoking Cessation, COPD
Effectiveness of Spirometry as a Motivational Tool to Quit Smoking
The aim of the study is to asses the efficacy of the spirometry and a minimal smoking cessation counselling intervention to quit smoking after a year in patients older than 40 years, smokers of more than 10 packs-year and without…
- Trial name
- ESPIMOAT (NCT01821885)
- Testing
- Spirometry and a brief advice to quit smoking, Brief advice to quit smoking
- Where
- Spain
- Volunteers
- 335 people
- Sponsor
- Basque Health Service
Insomnia Chronic, Insomnia Due to Medical Condition
Sleep Well Despite Persistent Pain Symptoms
Background: The prevalence of comorbid insomnia is 8-10 times higher in patients with chronic pain than in the general population.
- Conditions
- Insomnia Chronic, Insomnia Due to Medical Condition, Pain, Chronic
- Trial name
- Sleep-Well (NCT06351839)
- Testing
- Sleep-Well despite persistent pain, TAU (treatment-as-usual)
- Where
- Norway
- Volunteers
- 106 people
- Sponsor
- University of Tromso
Psychological Adaptation, Cognitive Change
Health Psychological Group Rehabilitation for Patients With Chronic Fatigue Syndrome (ME/CFS)
Chronic fatigue syndrome (ME/CFS) is a severe medical condition. It is characterized by long term fatique and other persisted symptoms, such as a cognitive disabilities and orthostatic intolerance.
- Conditions
- Psychological Adaptation, Cognitive Change, Adaptive Behavior, Functioning
- Trial name
- NCT04151693
- Testing
- Health Psychological Group Rehabilitation for Patients With Chronic Fatigue Syndrome (ME/CFS)
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Health Behavior, Chronic Disease
Marketing Workplace Chronic Disease Prevention
The objective of the project is to understand how best to help mid-size employers adopt evidence-based chronic disease prevention practices that improve employee health behaviors.
- Trial name
- NCT00452816
- Testing
- Workplace Solutions Consulting approach, Delayed intervention
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Washington
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