Clinical trials: Chronic Health Condition
Cognition, Affect (Mental Function)
PRECOG Pilot Project
This pilot study aims to investigate the chronic effects of a prebiotic blend on cognitive, affective and gut microbiome outcomes in healthy adults aged 60-75 years.
- Conditions
- Cognition, Affect (Mental Function), Gut Microbiome
- Trial name
- NCT06911957
- Testing
- Prebiotic blend
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Reading
Kidney Diseases, Chronic Kidney Diseases
NAVIGATE Kidney: A Multi-level Intervention to Reduce Kidney Health Disparities
The overarching goal of this project is to refine and adapt previous work on the NAVIGATE-Kidney project for individuals with CKD.
- Trial name
- NAV-Kidney (NCT06810622)
- Testing
- Community health worker intervention, Standard Care (in control arm)
- Where
- 2 sites in United States
- Volunteers
- 448 people
- Sponsor
- University of Colorado, Denver
Chronic Disease, Frailty
Association of Centre of Excellence Self-Administered Questionnaire (CESAM) Score and Frailty Levels
This study evaluates the association of the Self-Administered questionnaire (CESAM) score and its stratification of frailty in four levels with incident adverse health events in older community dwellers and to compare this…
- Conditions
- Chronic Disease, Frailty, Disability Physical
- Trial name
- NCT03962972
- Testing
- Frailty evaluation
- Where
- Canada
- Volunteers
- 1,741 people
- Sponsor
- Jewish General Hospital
Coronary Artery Disease
Outcomes, Patient Health Status, and Efficiency in Chronic Total Occlusion
This is an observational registry, sponsored by Saint Luke's Hospital. This study is to be conducted according to DHHS Guidelines, applicable state regulations, and local IRB policies and procedures.
- Trial name
- OPEN-CTO (NCT02026466)
- Where
- 11 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Saint Luke's Health System
Hearing Loss, Conductive, Hearing Loss, Mixed
Pilot Study to Evaluate the Long-term Chronic Care of Patients Who Could or do Utilize an Osseointegrated Device (OID)
The primary objective of the study is to evaluate OID hearing intervention on cognition among patients who could vs. do utilize an OID.
- Conditions
- Hearing Loss, Conductive, Hearing Loss, Mixed, Deafness, Unilateral
- Trial name
- NCT04899037
- Testing
- No intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of South Florida
Non-communicable Diseases (NCDs)
Community-Based Chronic Disease Care in Rural Lesotho
This ComBaCaL cohort study is to assess the impact of community-based, lay-led chronic disease screening and care interventions in rural Lesotho.
- Trial name
- ComBaCaL (NCT05596773)
- Where
- 2 sites in Lesotho, Switzerland
- Volunteers
- 17,500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Kidney Failure, Chronic
Spending and Outcomes for Complex Medicare Advantage Patients
This project will use data from a large network-model health maintenance organization that operates Medicare Advantage (MA) plans (CareMore) and fee-for-service Medicare data to (1) better understand the characteristics of…
- Trial name
- NCT02922361
- Volunteers
- 61,546 people
- Sponsor
- University of Pennsylvania
Cancer, Chronic Pain Due to Malignancy (Finding)
Safety and Efficacy of Smoked Cannabis for Improving Quality of Life in Advanced Cancer Patients
Cancer causes pain in many of the patients that it affects. Physicians specialized in palliative care help advanced cancer patients to maintain as good pain control as possible through the use of medications such as opioids.
- Trial name
- NCT03339622
- Testing
- PPP001
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Tetra Bio-Pharma
Chronic Spontaneous Urticaria
Improving Health and Wellbeing for People Diagnosed With Chronic Spontaneous Urticaria (CSU)
This study aims to investigate the influence of psychosocial factors on Chronic Spontaneous Urticaria (CSU). Preliminary research suggests a potential link between stress and the experience of CSU symptoms.
- Trial name
- NCT06108869
- Testing
- ABT Online Programme, Delayed Control group
- Where
- Ireland
- Volunteers
- 100 people
- Sponsor
- Royal College of Surgeons, Ireland
Chronic Low-back Pain, Chronic Pain
Digital Clinical Hypnosis for Chronic Pain Management
This ClinicalTrials.gov posting contains two randomized controlled trials. The study procedures were identical, except Study 1 was funded by NIH and enrolled adults with chronic low back pain, whereas Study 2 was funded by the UW…
- Trial name
- NCT06050083
- Testing
- Hypnosis audio recordings
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Pulmonary Disease, Chronic Obstructive
Sensor and Electronic Health Records (EHR) Integration Pilot Study
This is a pilot study that will evaluate the feasibility of collecting increasing amounts of clinical study data from subjects through sensor and web/app based methods and integrating it with data from their EHR to facilitate…
- Trial name
- NCT03357341
- Testing
- Mobile spirometer, Device sensor, Salbutamol
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease, Muscle Weakness
Cholecalciferol Supplementation in Strengthening Inspiratory Muscles in Cholecalciferol-Deficient Patients With Chronic Obstructive Pulmonary Disease
This phase IIb randomized trial studies how well cholecalciferol (vitamin D3) supplementation works in strengthening inspiratory muscles in cholecalciferol-deficient patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT02877641
- Testing
- Cholecalciferol, Laboratory Biomarker Analysis, Multivitamin
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Roswell Park Cancer Institute
Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease and Health Coaching
The aim of this study is to determine the effect of the health coaching approach applied to patients with Chronic Obstructive Pulmonary Disease on the perceived social support of the patients.
- Trial name
- NCT05711654
- Testing
- Health coaching
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Harran University
Chronic Disease
Association Analysis for Chronic Diseases Based on Resident Health Records by Using Big Data Methods
This is an observational study to analysis the association factors for common diseases, including chronic obstructive pulmonary disease, coronary artery disease, hypertension, diabetes etc, based on resident healthcare records.
- Trial name
- NCT03279822
- Testing
- not any intervention
- Where
- China
- Volunteers
- 10,000,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
End Stage Renal Disease, Depression
Cognitive Behavioral Treatment of Depression in ESRD Patients on Dialysis
Depression is second in frequency only to hypertension as a comorbid condition for End Stage Renal Disease (ESRD) patients. The presence of depression has been linked to lower quality of life, more medical comorbidities and…
- Trial name
- NCT00618475
- Testing
- Cognitive behavioral therapy
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Stroke
Home-Based Automated Therapy of Arm Function After Stroke Via Tele-Rehabilitation
Constraint-Induced Movement therapy, also known as CI therapy, is an approach to physical rehabilitation derived from basic behavioral and neuroscience research.
- Trial name
- NCT01157195
- Testing
- Tele-AutoCITE, CI therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Alabama at Birmingham
Traumatic Brain Injury, Brain Injuries, Traumatic
Scale-Up Evaluation Trial of the Diabetes Prevention Program to Improve Obesity and Cardiometabolic Health After Traumatic Brain Injury
The Investigators have proposed targeted efforts to address the feasibility, effectiveness, fidelity, and evaluation of the GLB-TBI Evidence Based Intervention (EBI) in a real world setting at a CDC-recognized site
- Conditions
- Traumatic Brain Injury, Brain Injuries, Traumatic, Brain Injury, Chronic
- Trial name
- GLB Scale-Up (NCT07648901)
- Testing
- Group Lifestyle Balance for People with TBI (GLB-TBI)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Baylor Research Institute
Chronic Kidney Disease Stage 4, Chronic Kidney Disease Stage 5
The Agenda-Setting for Kidney Disease Trial
The goal of this clinical trial is to learn if a tool with a list of discussion topics, called a structured clinical visit agenda-setting intervention (SAS), works for people with advanced chronic kidney disease (CKD) who receive…
- Trial name
- ASK (NCT07024953)
- Testing
- Chronic Kidney Disease Structured Agenda-Setting Tool
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Cerebral Palsy
Oral Health Status in a Group of Egyptian Children With Cerebral Palsy: A Cross-sectional Study
The aim of the study is to assess the oral health status in a group of Egyptian children with cerebral palsy.
- Trial name
- NCT05650593
- Where
- Egypt
- Volunteers
- 500 people
- Sponsor
- Cairo University
Depressive Disorders, End-stage Chronic Kidney Disease Treated With Hemodialysis
Evaluation of Depression Screening Methods Administered by Registered Nurses in Chronic Hemodialysis Patients
Hemodialysis is a vital replacement therapy for patients with end-stage chronic kidney disease, but it imposes a heavy, demanding, and prolonged management, associated with a significant deterioration in quality of life.
- Trial name
- IDE-3D (NCT07651436)
- Testing
- evaluate the psychometric performance of different modalities of hetero-assessment of depressive symptoms by nurses
- Where
- 2 sites in France
- Volunteers
- 450 people
- Sponsor
- Centre Hospitalier Annecy Genevois
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