Clinical trials: Chronic Health Condition
Hepatitis C, Chronic, Genotype 1
Quality of Life During Treatment of Chronic Hepatitis C (P05278/MK-4031-336)
The primary objective of this study is to evaluate the impact of chronic hepatitis C (CHC), and the treatment thereof with peginterferon alpha-2b (PEG) and ribavirin (RBV) according to standard clinical practice, on the…
- Conditions
- Hepatitis C, Chronic, Genotype 1, HCV-1
- Trial name
- VIDA (NCT00863109)
- Testing
- Peginterferon alfa-2b (PEG), Ribavirin (RBV)
- Volunteers
- 133 people
- Sponsor
- Merck Sharp & Dohme LLC
Pulmonary Disease, Chronic Obstructive, Depression
Problem-Solving Therapy for People With Major Depression and Chronic Obstructive Pulmonary Disease
This study will evaluate the effectiveness of problem-solving therapy combined with treatment adherence procedures in treating older people with major depression and chronic obstructive pulmonary disease.
- Trial name
- NCT00601055
- Testing
- Problem Solving-Rx Adherence (PSA), PID-C
- Where
- 2 sites in United States
- Volunteers
- 101 people
- Sponsor
- Weill Medical College of Cornell University
Low Back Pain
Low Back Pain Patient Education Evaluation
Back pain is one of the most common of all symptoms. It is also a great cause of days lost from work and visits to health care providers.
- Trial name
- NCT00000408
- Testing
- Patient education evaluation
- Where
- United States
- Volunteers
- 580 people
- Sponsor
- Stanford University
Chronic Obstructive Pulmonary Disease (COPD), Smoking Cessation
Personalized Smoking Cessation Infographic in COPD
This study assesses the effect of a personalized smoking cessation infographic on physician smoking cessation counseling rates and smoking cessation pharmacotherapy prescription rates.
- Trial name
- NCT04119934
- Testing
- Smoking Cessation Intervention Tool
- Where
- Canada
- Volunteers
- 83 people
- Sponsor
- Unity Health Toronto
Dyspnea, Chronic Obstructive Pulmonary Disease
Menthol for Dyspnea Relief in Health and COPD
Menthol inhalation (MI) is a novel and promising treatment option for acute relief of dyspnea, however, the underlying ventilatory and/or neural related mechanisms for this relief in symptoms remain unknown.
- Trial name
- MENTHODYSC (NCT05785026)
- Testing
- Menthol inhalation, Strawberry scent, Menthol inhalation and facial airflow
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Intellectual Disability, Developmental Disability
Research Engagement With People With Intellectual and Developmental Disabilities
The objectives of this project are to to build sustainable regional communities of Intellectual or Developmental Disabilities (IDD) stakeholders to provide ongoing input to research priorities, methodological processes, and…
- Conditions
- Intellectual Disability, Developmental Disability, Chronic Conditions, Multiple
- Trial name
- PCORI (NCT04182347)
- Testing
- Health Research ToolKit Development
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
COPD, Obesity
Effects of Obesity on COPD
The purpose of this study is to investigate whether obese COPD patients experience more or less discomfort in daily life. Furthermore the investigators will evaluate if body composition or body fat distribution has effects on…
- Conditions
- COPD, Obesity, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT06474858
- Where
- Netherlands
- Volunteers
- 166 people
- Sponsor
- Rijnstate Hospital
Hyperlipidemia, Diabetes
Tele-Pharmacy Intervention to Improve Treatment Adherence
The purpose of this cluster randomized controlled trial is to evaluate whether a novel tele-pharmacist-based intervention for patients with hyperlipidemia, hypertension, and diabetes improves medication adherence, disease…
- Conditions
- Hyperlipidemia, Diabetes, Hypertension
- Trial name
- STIC2IT (NCT02512276)
- Testing
- Telepharmacist intervention
- Where
- United States
- Volunteers
- 4,078 people
- Sponsor
- Brigham and Women's Hospital
Chronic Obstructive Pulmonary Disease
Oxygen Therapy Remote Monitoring in COPD Patients.
Background : Long-term oxygen therapy is prescribed for patients with severe COPD. The aim of oxygen therapy is to administer oxygen at a concentration level higher than that of ambient air, in order to treat or prevent the…
- Trial name
- NCT05473780
- Where
- 36 sites in France
- Volunteers
- 159 people
- Sponsor
- Vivisol
Osteoarthritis
Evolution of the State of Health of Patients Undergoing Surgery for Osteoarticular Surgery
Osteoarticular surgery is frequently associated with the occurrence of moderate to severe postoperative pain. This pain can persist and become chronic post-surgical pain that is often debilitating.
- Trial name
- EPOPEE (NCT05527860)
- Where
- France
- Volunteers
- 4,000 people
- Sponsor
- University Hospital, Strasbourg, France
Chronic Pain
Reaching Rural Veterans: Applying Mind-Body Skills for Pain Using a Whole Health Telehealth Intervention - UG3 Pilot Study
This project addresses the significant challenge of providing evidence-based non-pharmacologic pain management to rural-dwelling Veterans in the VA healthcare system who have chronic pain.
- Trial name
- RAMP-Pilot (NCT06568250)
- Testing
- RAMP program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Pancreatic Cancer, Diabetes
Artificial Intelligence-based Early Screening of Pancreatic Cancer and High Risk Tracing (ESPRIT-AI)
Pancreatic cancer is one of the most fatal malignancies with a 5-year survival rate of only ~6%[1]. The reasons for this high mortality rate can be attributed to several factors, of which perhaps the most important is delayed…
- Conditions
- Pancreatic Cancer, Diabetes, Familial Pancreatic Cancer, Pancreatic Cystic Neoplasm
- Trial name
- ESPRIT-AI (NCT04743479)
- Testing
- high-resolution MRI/CT examinations
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Changhai Hospital
Caregiver Burden, Health Literacy
Burden of Care and Health Literacy of Caregivers in the Emergency Department
This study aims to investigate the relationship between caregiver burden and health literacy among primary caregivers of patients with chronic diseases presenting to the emergency department.
- Conditions
- Caregiver Burden, Health Literacy, Chronic Disease, Emergency Service Utilization
- Trial name
- NCT07666373
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Smoking Cessation, Chronic Obstructive Pulmonary Disease (COPD)
SAW Lung Microbiome Study in Smokers and Never-smokers
The trial aims to analyse changes in the microbiome of the lower airways after smoking cessation. Microbiome analyses (upper airway swabs, bronchoalveolar lavage, transbronchial brushing) are conducted in smokers before and 6…
- Conditions
- Smoking Cessation, Chronic Obstructive Pulmonary Disease (COPD), Healthy, Microbial Colonization
- Trial name
- NCT03562442
- Testing
- Smoking cessation
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Research Center Borstel
Lung Diseases
Short Active Lives Survey in Chronic Lung Conditions
Short Actives Lives Survey is a common tool used to measure physical activity in the UK population. Self-reported measures such as the Short Active Lives Survey can be prone to bias.
- Trial name
- NCT04080583
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Lincoln
Hepatitis C
Ribavirin Pre-treatment Followed by Combined Standard Therapy in Hepatitis C Virus (HCV) Recipients
The results of antiviral therapy in patients with recurrent hepatitis C after liver transplantation are lower than standard. Ribavirin has immune-modulating effects and seems to be crucial to optimize viral treatment.
- Trial name
- RBV (NCT00993122)
- Testing
- ribavirin pre-treatment
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Roma La Sapienza
Constipation
An Observational Study to Evaluate the Quality of Life in Korean Female Participants With Chronic Constipation
The purpose of this observational study is to investigate health related quality of life (QoL) in Korean female participants with chronic constipation (long term decreased number of or difficulty making bowel movements) having…
- Trial name
- NCT01902537
- Testing
- Prucalopride; observational study
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Janssen Korea, Ltd., Korea
Knee Osteoarthritis, Knee Arthritis
ROMTECH PortableConnect Rehabilitation Device Usage Post Unilateral Total Knee Arthroplasty (TKA)
ROMTech is focused on transforming the healthcare market by delivering lower extremity rehabilitation systems that are effective, efficient for patient use, cost-effective, and provide better patient outcomes while simultaneously…
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Disease
- Trial name
- NCT04497129
- Testing
- ROMTech PortableConnect, Traditional Rehabilitation and CPM Device
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- ROM Technologies, INC
Pain Predominant Chronic Multisymptom Illness
Health Coaching for Chronic Multisymptom Illness
The National Academy of Medicine (NAM) labels chronic pain as one of the most extensive health care issues facing our society with "severe impacts on all aspects of the lives of its sufferers."1 Pain predominant chronic…
- Trial name
- NCT04157101
- Testing
- Health Coaching, Supportive Psychotherapy
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- VA Office of Research and Development
Chronic Pain, Musculoskeletal Pain
National Survey of Chronic Occupational Pain in Thai Anesthesia Providers
The purpose of this nationwide cross-sectional survey is to determine the prevalence, multidimensional impacts, and associated factors of chronic occupational pain among anesthesiologists and nurse anesthetists in Thailand.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Occupational Pain, Occupational Diseases
- Trial name
- NCT07778381
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Mahidol University
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