Clinical trials: Chronic Health Condition
Atrial Fibrillation
Optimal Antiplatelet Therapy Following Left Atrial Appendage Closure in Dialyzed Patients
SAFE-LAAC CKD Trial has been designed to gather data on the most optimal strategy of antiplatelet therapy after transcatheter left atrial appendage occlusion with Amplatzer or WATCHMAN device in patients with the end-stage renal…
- Trial name
- SAFE LAAC CKD (NCT05660811)
- Testing
- short postimplantation dual antiplatelet therapy, extended postimplantation dual antiplatelet therapy, long-term treatment with a single antiplatelet agent
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Chronic Medical Condition
Peer Wellness Enhancement For Patients With Serious Mental Illness and High Medical Costs
This research addresses the important public health crisis that people with serious mental illness (SMI) are dying10-20 years younger than the average population, primarily due to chronic, untreated medical conditions.
- Trial name
- NCT03673852
- Testing
- WE Harambee, Behavioral Health Home Enrollment
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University
Treatment Engagement
Feasibility Study of Single-session Solution Focused Consultation to Enhance Treatment Engagement
This research aims to explore whether a single-session solution-focused consultation (SSC) can increase mental health service engagement among patients with comorbid chronic physical diseases and mental health problems (CPDMHP).
- Trial name
- NCT07116655
- Testing
- Single-session solution focused consultation, Single-session supportive intervention
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- Nanyang Technological University
Malaria,Falciparum, Malaria
CHILD (Child Health and Infection With Low Density) Malaria
This trial will assess the long-term health and socioeconomic impact of interventions targeting low-density malaria infection (LMI) among children in Tanzania
- Trial name
- NCT05567016
- Testing
- Active case detection using molecular testing (ACDm), Passive case detection using molecular testing (PCDm), Control (standard of care)
- Where
- Tanzania
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Chronic Obstructive Pulmonary Disease (COPD), Anxiety
Pilot Study on Mindfulness Based Stress Reduction (MBSR) in Patients With Chronic Obstructive Pulmonary Disease (COPD)
This two-phase exploratory pilot study investigates the impact of a Mindfulness-Based Stress Reduction (MBSR) program on patients with chronic obstructive pulmonary disease (COPD) undergoing pulmonary rehabilitation.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Anxiety, Depression Disorders, Stress
- Trial name
- NCT07593521
- Testing
- Mindulness Based Stress Reduction program
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- Université Libre de Bruxelles
COPD, COPD (Chronic Obstructive Pulmonary Disease)
Mobile Health Self-Management Intervention for Patient With Chronic Obstructive Pulmonary Disease
This clinical trial aims to evaluate the effectiveness of a pharmacist-led interactive mobile health intervention (serious game) in adults aged 50 years and older with chronic obstructive pulmonary disease (COPD).
- Trial name
- AERIS (NCT07469904)
- Testing
- Pharmacist-Led mHealth Serious Game, Usual Care
- Where
- Indonesia
- Volunteers
- 126 people
- Sponsor
- Universitas Katolik Widya Mandala Surabaya
Chronic Stress, Stool Frequency
Assessing Diet, Stress Scores, and Other Health Metrics in Healthy Northern California Adults
The purpose of this study is to gather health and nutrition data from the population of Davis, CA and surrounding areas. This data will be used to help us test and improve our study procedures for a larger planned study on peanut…
- Conditions
- Chronic Stress, Stool Frequency, Food Allergies, Diet Surveys
- Trial name
- NCT07265648
- Testing
- Online Survey
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Hypertension, Diabetes
Developing a Learning Health System for Primary Care in Thailand
Research question: Can a Learning Health System (LHS) approach improve delivery of care and reduce inequalities in outcomes for people with hypertension and related non-communicable diseases (NCDs) compared to routine care in…
- Conditions
- Hypertension, Diabetes, Kidney Disease, Primary Care
- Trial name
- NCT06873243
- Testing
- Learning Health System Approach
- Where
- Thailand
- Volunteers
- 419 people
- Sponsor
- Queen Mary University of London
Diabetes Mellitus, Chronic Kidney Diseases
The Multi-Ethnic Lifestyle Study
The study design is cross-sectional using a self-completion questionnaire in an English speaking multi-ethic population within Leicester and Leicestershire.
- Conditions
- Diabetes Mellitus, Chronic Kidney Diseases, Cardiovascular Diseases, Obstructive Sleep Apnea
- Trial name
- MELS (NCT04256720)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 9,500 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Knee Osteoarthritis (Knee OA), Knee Pain Chronic
Advanced Brain Imaging-TKA (fMRI-TKA)
Knee replacement surgery is a common and effective treatment for pain and mobility loss, yet up to 1 in 5 patients remain dissatisfied after surgery due to ongoing pain or difficulty with daily activities.
- Conditions
- Knee Osteoarthritis (Knee OA), Knee Pain Chronic, Brain Network Connectivity, Patient Satisfaction
- Trial name
- fMRI-TKA (NCT07464080)
- Testing
- fMRI Brain Scan
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ottawa Hospital Research Institute
Pain Measurement, Pain, Chronic
Qualitative Study for Pain Measurement Using Innovative Health Technology
The present study is a multicenter, explorative, qualitative study. The primary endpoint of this study is to evaluate to which extent the collection of data with regard to pain caused by illness or treatment can be optimized…
- Conditions
- Pain Measurement, Pain, Chronic, Pain, Acute, Pain, Cancer
- Trial name
- QualiPain (NCT03727373)
- Where
- 2 sites in Germany
- Volunteers
- 8 people
- Sponsor
- University Hospital Schleswig-Holstein
Osteoarthritis, Knee
Positive Minds Strong Joints for Knee Osteoarthritis
The aim of this research study is to test the feasibility of a physical and mental health intervention (Positive Minds, Strong Joints or PMSJ) for Black adults with knee osteoarthritis (OA).
- Trial name
- PMSJ (NCT06493903)
- Testing
- Positive Minds, Strong Joints
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Boston University Charles River Campus
Chronic Disease, Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight
Truway Diagnostic Tools in Primary Care
This study evaluates the effectiveness of Truway Health-sourced portable diagnostic devices, including ultrasound and blood glucose monitors, in early detection of chronic conditions in outpatient primary care settings.
- Conditions
- Chronic Disease, Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight, Hypertension, Cardiovascular Disease Acute
- Trial name
- TruDxPC (NCT07209527)
- Testing
- Truway Portable Ultrasound Device, Truway Blood Glucose Monitor, Standard Oral Hypoglycemic Agent
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Truway Health, Inc.
Chronic Disease
Strategies Empowering Activities in Everyday Life: An Internet-based Occupational Therapy Intervention
The purpose of the study is to evaluate the feasibility, potential outcomes and the implementation process of a second updated version of an internet-based intervention in occupational therapy, focusing on self-management in…
- Trial name
- SEE2:0 (NCT06484322)
- Testing
- Strategies Empowering Activities in Everyday life (SEE 2.0)
- Where
- 2 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Luleå Tekniska Universitet
Heart Failure
Improvement of a Digital Health Platform for Remote Monitoring of Patients With Heart Failure
In the present project, we propose to run an observational study in order to create a huge dataset with telemonitoring data from heart failure (HF) patients.
- Trial name
- DHEART (NCT05708846)
- Testing
- Telemonitoring
- Where
- 7 sites in Romania, Spain
- Volunteers
- 154 people
- Sponsor
- humanITcare
Chronic Kidney Disease, Diabetes
CKD Awareness, Referrals, Education, and Support Intervention for Early-Stage CKD
The goal of this pilot clinical trial is to learn if an intervention delivering education, motivational support, and social support can prevent worsening kidney disease in adults with diabetes and early-stage kidney disease.
- Trial name
- CARES (NCT07210710)
- Testing
- CKD Awareness, Referrals, Education, and Support (CARES), Attention control
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Illinois Chicago
Chronic Kidney Diseases
Digital Dyadic Empowerment Program on Lifestyle Modification for Chronic Kidney Disease Management
The goal of this clinical trial is to find out if the Digital Dyadic Empowerment Program (DDEP) can help people with chronic kidney disease (CKD) and their care partners make healthy lifestyle changes.
- Trial name
- DDEP (NCT06756113)
- Testing
- Digital Dyadic Empowerment, Usual Care
- Where
- Taiwan
- Volunteers
- 208 people
- Sponsor
- National Cheng Kung University
Cardiovascular Diseases, Chronic Disease
Improving Therapeutic Adherence in Cardiovascular Secondary Prevention.
The goal of this open label randomized controlled trial is to evaluate the efficacy of an intervention through health education based on the Chronic Care Model's implementation to increase therapeutic adherence in patients with…
- Conditions
- Cardiovascular Diseases, Chronic Disease, Secondary Prevention, Coronary Disease
- Trial name
- AT-PSC (NCT06510946)
- Testing
- (Health education program) To increase therapeutic adherence in patients with secondary prevention for cardiovascular disease
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Opioid-use Disorder, Opioid-related Disorders
An Observational Study of Environmental and SocioEconomic Factors in Opioid Recovery
The RECOVER Study will examine clinical, environmental and socioeconomic factors in recovery from opioid use disorder (OUD) over a 24-month period following exit from a Phase III clinical program for a buprenorphine…
- Trial name
- RECOVER® (NCT03604861)
- Testing
- Not applicable - no defined intervention
- Where
- 35 sites in United States
- Volunteers
- 534 people
- Sponsor
- Indivior Inc.
Low Back Pain
Chronic Low Back Pain and Primary Health Care
Kentucky ranks 2nd in disability among states, with chronic low back pain (CLBP) as a major disability, especially in the investigators rural areas. Kentucky and U.S.
- Trial name
- NCT01147120
- Testing
- Progressive Muscle Relaxation (PMR), Clinical Massage Therapy (CMT)
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- William G Elder JR
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