Clinical trials: Chronic Health Condition
Chronic Heart Failure (CHF)
Effect of a Structured Nursing Intervention Incorporating Sleep Hygiene and Cognitive-Behavioral Strategies on Sleep Quality Among Patients With Chronic Heart Failure
This study aims to evaluate the effectiveness of a structured nursing intervention incorporating sleep hygiene education and cognitive-behavioral strategies on improving sleep quality among patients with chronic heart failure.
- Trial name
- Heart failure (NCT07747597)
- Testing
- Structured Nursing Intervention Incorporating Sleep Hygiene and Cognitive-Behavioral Strategies
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al-Zaytoonah University of Jordan
Cervical Radiculopathy, Cervical Disc Herniation
Clinical Outcomes of Magnesium Sulfate in Cervical Interlaminar Epidural Steroid Injection
This single-center observational comparative cohort study evaluates clinical outcomes following two cervical interlaminar epidural steroid injection protocols used in routine care for chronic cervical radicular pain due to…
- Trial name
- NCT07788820
- Testing
- Magnesium Sulfate, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Marmara University
Stress
Managing Stress and Social Ties for Health Aging
There has been a dramatic rise from 46% to 59% in the percentage of households with only 1-2 people from 1970 to 2000. A 40% increase in the number of people living alone is projected for 2010.
- Trial name
- NCT01204021
- Testing
- Tai Chi Chih, Stress Education Control
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Chronic Bronchitis
SYMPROVE III: Health Services Research Study for Treatment of the Moderate and Severe Acute Exacerbations of Chronic Bronchitis (AECB)
In this study data of patients with moderate or severe acute exacerbations of chronic bronchitis (AECB) were collected. There were two different cohorts which were compared (Moxifloxacin and other antibiotics) concerning…
- Trial name
- SYMPROVE III (NCT00879008)
- Testing
- Moxifloxacin (Avelox, BAY12-8039)
- Where
- Germany
- Volunteers
- 345 people
- Sponsor
- Bayer
COPD
Impact of Fixed TRIple Therapy With Beclometasone/Formoterol/Glycopyrronium DPI (Trimbow® in NEXThaler Device) in Chronic Obstructive PulmoNary Disease in rEal-world Settings: Health-related Quality of Life Patient' eXpectations and characterisTics: the TriNEXT Study
This is an observational, prospective, multicentric, cohort study conducted in France to evaluate the QoL in COPD patients treated with TRIMBOW NEXThaler 88/5/9 in a routine clinical practice setting.
- Trial name
- TriNEXT (NCT05948891)
- Testing
- Beclometasone/Formoterol/Glycopyrronium 88 µg/5 µg/9 µg DPI (Trimbow® 88 µg/5 µg/9 µg in NEXThaler device)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Chiesi SAS
Chronic Obstructive Pulmonary Disease
Effects of Elastic Tape on Pulmonary Rehabilitation of Patients with Chronic Obstructive Pulmonary Disease
Evaluate the effect of the use of elastic tape in chest wall and abdomen in the physical capacity, psychosocial distress levels, quality of life and anxiety, and depression symptoms of individuals with moderate to very severe…
- Trial name
- ETReaCOPD (NCT05939999)
- Testing
- Experimental: Elastic tape (ET)
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- University of Sao Paulo General Hospital
Frailty, Chronic Pain
Effectiveness of a Physical Activity Intervention for Pre-frail Older Adults With Chronic Pain.
The purpose of this investigation is to evaluate the effectiveness of a multicomponent structured physical exercise program for adults aged 65 years or more, classified as pre-frail and with chronic pain to improve the Perceived…
- Conditions
- Frailty, Chronic Pain, Old Age; Debility
- Trial name
- NCT04045535
- Testing
- Physical Activity Program, Usual care
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Gerencia de Atención Primaria, Madrid
Exercise Therapy, Behavior and Behavior Mechanisms
Health-Enhancing Adapted Physical Activity Program at "Mon Stade"
Introduction: Regular practice of exercise or physical activity (PA) is a recognized intervention as a determinant of good health acquisition, maintenance, or recovery for a large number of chronic pathologies.
- Conditions
- Exercise Therapy, Behavior and Behavior Mechanisms, Adherence, Patient, Lifestyle, Sedentary
- Trial name
- SESAME (NCT04716322)
- Testing
- Adapted Physical Activity
- Where
- France
- Volunteers
- 2,024 people, healthy volunteers welcome
- Sponsor
- Mon Stade Sports Medicine Centre
Cerebral Palsy
HMB Cerebral Palsy Pilot Study
This is a pilot study of β-hydroxy-β-methylbutyrate (HMB) + Vitamin D3 supplementation in adolescents with cerebral palsy. The primary objective is to quantify safety, compliance, and acceptability of daily combined HMB + Vitamin…
- Trial name
- NCT05384951
- Testing
- HMB + Vitamin D3
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Gillette Children's Specialty Healthcare
Chronic Pain
Manage My Pain at Chronic Pain Clinics
The overall objective of this Early Adoption project is to gather evidence for how Managing My Pain Program (MMP), a novel digital pain management application can enable better care at home for chronic pain sufferers in the…
- Trial name
- NCT04762329
- Testing
- Manage My Pain (MMP) digital pain app group
- Where
- Canada
- Volunteers
- 246 people
- Sponsor
- University Health Network, Toronto
Chronic Kidney Diseases
Kidney Coordinated Health Management Partnership
As part of a 42-month pragmatic, cluster randomized trial in 1,650 primary care patients with high-risk Chronic Kidney Disease (CKD), the investigators will test the effectiveness of a multifaceted Electronic Health Record…
- Trial name
- Kidney-CHAMP (NCT03832595)
- Testing
- EHR-based PHM, Usual Care
- Where
- United States
- Volunteers
- 1,596 people
- Sponsor
- University of Pittsburgh
Hypertension, Inflammation
Dietary Nitrate, Vascular Function and Inflammation
The risk for cardiovascular diseases (CVD) increases with advancing age. Developing effective lifestyle-based strategies to promote, preserve or restore cardiovascular health with aging is a high priority.
- Trial name
- NCT04584372
- Testing
- High-nitrate intervention, Low-nitrate intervention
- Where
- 2 sites in Austria
- Volunteers
- 20 people
- Sponsor
- University of Vienna
Post-Acute Sequelae of SARS-CoV-2 Infection, Long COVID
Observational Study of Intranasal IVIG in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Patients Undergoing Medical Tourism
This observational study is being conducted by Healing Hope International to collect real-world data on an emerging treatment approach for Long COVID in patients with immunodeficiency.
- Conditions
- Post-Acute Sequelae of SARS-CoV-2 Infection, Long COVID, Long COVID Fatigue, Long COVID Syndrome
- Trial name
- IVIG-LC (NCT06992401)
- Volunteers
- 50 people
- Sponsor
- Tamara C Tamas
Diabetes Type 2, Renal Failure
A Study of the Usefulness & Usability of a Healthcare IT System for Managing Multi-morbidity and Poly-pharmacy
To assess the acceptability of a personalised ICT tool that facilitates coordinated care planning, treatment optimisation and patient self-management for patients with multiple long term conditions and their team of health…
- Conditions
- Diabetes Type 2, Renal Failure, Heart Failure, Depression
- Trial name
- C3-Cloud (NCT03834207)
- Testing
- Use of the C3-Cloud IT system
- Where
- 3 sites in Spain, Sweden and 1 more
- Volunteers
- 672 people
- Sponsor
- Dr Christopher Marguerie
CKD Stage 4, CKD Stage 5
Frailty, Cognitive Function and Health-related Quality of Life in Older Adults With Advanced Chronic Kidney Disease.
This observational study explores the impact of cognitive impairment and frailty in older adults with advanced chronic kidney disease ].
- Conditions
- CKD Stage 4, CKD Stage 5, Frailty, Cognitive Impairment
- Trial name
- NCT05705011
- Where
- Romania
- Volunteers
- 240 people
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Low Back Pain, Chronic Pain
Nonpharmacologic Pain Management in FQHC Primary Care Clinics
The goal of this study is to improve pain management and reduce opioid reliance for patients with chronic back pain in Utah Federally-Qualified Health Centers (FQHCs).
- Trial name
- BeatPain Utah (NCT04923334)
- Testing
- Brief Pain Teleconsult, Telehealth Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of Utah
Kidney Diseases, Cardiometabolic Risk Factors
Feasibility Trial of a Stakeholder-enhanced Lay-navigator-delivered Intervention (ImPart-Multi)
The purpose is to explore the feasibility and acceptability of participation in a decision-support training program led by lay navigators.
- Trial name
- ImPart-Multi (NCT06067009)
- Testing
- ImPart-Multi - IMproving the decisional PARTnership of Chronic Kidney Disease Dyads with concurrent metabolic disease
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Alabama at Birmingham
Chronic Inflammation, Chronic Pain
Gulf War Illness Inflammation Reduction Trial
The primary objective of this clinical trial is to determine if treatment with an anti-inflammatory drug (delayed-release prednisone) improves the health-related quality of life (HRQOL) of veterans with Gulf War Illness (GWI).
- Conditions
- Chronic Inflammation, Chronic Pain, Fatigue, Cognitive Impairment
- Trial name
- GWIIRT (NCT02506192)
- Testing
- Modified-Release Prednisone
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Chronic Pancreatitis
Effect of Acetyl-L-carnitine on Chronic Pancreatitis
An open label pilot study will determine the effect of the amino acid nutritional supplement acetyl-L-carnitine (ALC) on pain, quality of life, well-being, and serum pro-inflammatory mediator and oxidative stress levels in…
- Trial name
- NCT02538146
- Testing
- acetyl-L-carnitine 1000mg 2X per day for 3 months
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Karin High
Age:18-70 Years, Acute Severe Disease
Metabolomics Dynamics Study for Severe Patient
Acute severe disease is a major public health challenge that often affects young adults.In past decade, there are lot of new techniques have been developed that aim to improve the outcome of acute severe disease, But few of these…
- Conditions
- Age:18-70 Years, Acute Severe Disease, Acute Physiology And Chronic Health Evaluation(APACHE)II>10
- Trial name
- NCT02164786
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sichuan Academy of Medical Sciences
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