Clinical trials: Chronic Hemodialysis
End-Stage Renal Disease
High Flux Hemodialysis Thrice Versus Once
To investigate the influence of different dialysis frequencies on the outcome of end-stage renal disease patients undergoing chronic hemodialysis therapy.
- Trial name
- NCT00714662
- Testing
- high flux hemodialyzer (FX-60, FX-80 or FX-100)
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
Renal Failure Chronic, Hepatitis C
Direct-acting Antiviral Therapy to Prevent HCV Infection for HCV Positive Donor to HCV Negative Recipient Kidney Transplant
Open label single center study for the donation of HCV positive kidneys to HCV negative recipients with interventional treatment to prevent HCV transmission upon transplantation.
- Trial name
- NCT03093740
- Testing
- Zepatier, Zepatier plus Sofosbuvir
- Where
- United States
- Sponsor
- Massachusetts General Hospital
End-Stage Renal Disease (ESRD)
Intracellular Phosphate Concentration Evolution During Hemodialysis by MR Spectroscopy
End-stage renal disease is associated with hyperphosphatemia due to a decrease of renal phosphate excretion. This hyperphosphatemia is associated with an increase of cardiovascular risk and mortality.
- Trial name
- CIPHEMO (NCT03119818)
- Testing
- Phosphorus (31P) magnetic resonance spectroscopy, Hemodialysis
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Hospices Civils de Lyon
End Stage Renal Failure
Effect of Reducing Phosphorus Absorption on Cardiac Biomarkers in Hemodialysis Patients
Hyperphosphatemia and elevated cardiac biomarkers are two key characteristics of patients in end stage renal diseases(ESRD),however the majority of whom are in the absence of acute coronary syndrome(ACS).
- Trial name
- NCT01781156
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai 10th People's Hospital
Cardiovascular Disease, Chronic Kidney Disease Patients
A Study Using L5 as a Risk Factor of Cardiovascular (CV) Disease in Chronic Renal and Dialytic Patients
The purpose of this study is to determine whether L5, one of the Low Density Lipoproteins, is an effective predicting factor for cardiovascular disease in chronic renal and hemodialytic patients.
- Conditions
- Cardiovascular Disease, Chronic Kidney Disease Patients, Hemodialytic Patients, High LDL Level
- Trial name
- L5 (NCT01236820)
- Where
- Taiwan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Renal Failure, Chronic, End-Stage Renal Disease
PK of Serelaxin in Severe Renal Impairment and ESRD
The study is designed to evaluate the pharmacokinetics, safety and tolerability, immunogenicity and pharmacogenetics of a single dose of serelaxin/RLX030 in patients with severe renal impairment and end-stage-renal-disease (ESRD)…
- Trial name
- CRLX030A2102 (NCT01875523)
- Testing
- Serelaxin
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
End Stage Renal Disease
Comparison of the Clinical Performance of 3 THERANOVA 400 Dialyzer Prototypes With a High-Flux Dialyzer in Hemodialysis Mode
The study investigates the performance of a new dialyzer (Theranova 400) containing a membrane with increased pore sizes. The performance will be determined by the removal of middle molecules (with different molecular size) from…
- Trial name
- NCT02377570
- Testing
- THERANOVA 400 dialyzer prototype AA, THERANOVA 400 dialyzer prototype BB, THERNOVA 400 dialyzer prototype CC
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Vantive Health LLC
Hyperparathyroidism; Secondary, Renal
Efficacy and Safety of Cinacalcet in Ca, P and iPTH Levels in Patients With Mild, Moderate and Severe SHPT
1. To evaluate achievement ratio of iPTH,Calcium and phosphorus after taking Cinacalcet HCL in hemodialysis subjects with mild, moderate and severe SHPT; 2.
- Trial name
- ACTIVE (NCT03123406)
- Testing
- Cinacalcet HCl
- Where
- China
- Volunteers
- 750 people
- Sponsor
- Kyowa Kirin China Pharmaceutical Co., Ltd.
Chronic Kidney Diseases
Efficacy of Combined Low- and High- Frequency Stimulation in Peripheral Muscle Function During Hemodialysis
Chronic kidney disease is a systemic disease that affects not only renal function, but also, several organs, bringing social, psychological and physical impact to the patients under this condition.
- Trial name
- NCT03779126
- Testing
- Electrical stimulation
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- Hospital Sirio-Libanes
Chronic Kidney Disease, Metabolic Acidosis
Comparison of Standard Versus Low Bicarbonate Hemodialysis
This study will compare acid-base changes during hemodialysis treatments with a standard dialysis bath versus a lower bicarbonate dialysis bath, and aims to define the factors that limit equilibration of the bicarbonate…
- Trial name
- NCT01777178
- Testing
- Low bicarbonate dialysis
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Albert Einstein College of Medicine
Chronic Kidney Disease
Effect of Statins on IgG, IgA and IgM Level in Chronic Hemodialysis Patients
This is double blind randomized controlled trial on the statins effects on serum IgG, IgA and IgM level in chronic hemodialysis patients in Bandarabbas
- Trial name
- NCT01305317
- Testing
- Lipitor
- Where
- Iran
- Volunteers
- 74 people
- Sponsor
- Hormozgan University of Medical Sciences
End-stage Renal Disease
Study of High Sensitive Troponin-I Level in End-stage Renal Disease Patients Receiving Hemodialysis
This study objective is to compare the high sensitive troponin-I level in end-stage renal disease patients received hemodialysis without acute cardiovascular event with healthy population.
- Trial name
- NCT02572466
- Testing
- Hemodialysis
- Where
- Thailand
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Hemodialysis, Kidney Disease, Chronic
Intradialysis Exercise Functional Capacity, Body Composition and Survival in Hemodialysis Patients
Chronic kidney disease and renal replacement treatments (hemodialysis, peritoneal dialysis, kidney transplant) produce various alterations at the level of muscle, bones, fat content and the heart; can alter physical capabilities…
- Conditions
- Hemodialysis, Kidney Disease, Chronic, Physical Activity, Physical Deconditioning
- Trial name
- NCT06788054
- Testing
- intradialysis exercise
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Universidad de Guanajuato
End-stage Renal Disease, HCV Coinfection
Ombitasvir/ Paritaprevir / Ritonavir Plus Ribavirin in Management HCV and End-stage Kidney Disease
Management of patients with hepatitis C virus (HCV) related liver disease with concomitant co-morbidity was challenging, especially in the period before the era of new direct-acting antiviral (DAA) agents.
- Trial name
- NCT03499639
- Testing
- Ombitasvir / Paritaprevir / Ritonavir /Ribavirin Oral Tablet
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Assiut University
Chronic Hemodialysis Patients
Chronic Anticoagulation With a Reduced Dose Regimen of Rivaroxaban in End-stage Renal Disease Patients
Atrial fibrillation is the most frequent cardiac rhythm disorder and its prognosis is essentially marked by the risk of embolic events.
- Trial name
- CARD-AXA (NCT05410275)
- Testing
- Rivaroxaban
- Where
- 2 sites in France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Tours
Chronic Kidney Disease - Stage V, Chronic Kidney Disease on Hemodialysis
Outcomes of Renal Replacement in Mexico
A descriptive, observational, prospective, multicenter study aimed at describing the main clinical outcomes of patients with chronic kidney disease receiving any form of renal replacement therapy in Mexico.
- Trial name
- ORReMex (NCT07474805)
- Volunteers
- 290 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Hemodialysis, End Stage Chronic Renal Failure
Mindfulness for Saudi Hemodialysis Patients
This study aims to evaluate whether an MBI improves sleep quality, emotional symptoms (depression, anxiety, stress), emotion regulation, and trait mindfulness among adults with ESRD on HD.
- Trial name
- MSHP (NCT07816354)
- Testing
- Mindfulness-Based Intervention
- Where
- Saudi Arabia
- Volunteers
- 38 people
- Sponsor
- Jordan University of Science and Technology
End Stage Renal Disease, Hemodialysis Patients
Association Between Dose Dialysis by Kt and Mortality
The aim of this study is to assess whether patients receiving current recommendations of an adequate dialysis dose by Kt adjusted for body surface area improved survival at 24 months compared to those who do not get it, as well…
- Trial name
- NCT01932853
- Where
- Spain
- Volunteers
- 6,129 people
- Sponsor
- NephroCare Spain
End-Stage Renal Disease
Study of Home-Embedded Palliative Care for Hemodialysis- (and Peritoneal-) Dependent End-Stage Renal Disease
Home palliative care needs are often under-recognized in patients with End-Stage Renal Disease (ESRD). This pilot study is designed to evaluate the effectiveness of referrals to home palliative care services in improving patient…
- Trial name
- SHEPHERD 2 (NCT06144281)
- Testing
- Nudge for PHPC NP Referral
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- University of Pennsylvania
End-Stage Renal Disease
Pharmacokinetics Study of Donepezil HCl in Subjects Receiving Haemodialysis.
The purpose of this study is to investigate the pharmacokinetics of donepezil HCl 3 mg in subjects with end-state renal disease who were receiving haemodialysis.
- Trial name
- NCT01063556
- Testing
- donepezil HCl
- Where
- Japan
- Volunteers
- 6 people
- Sponsor
- Eisai Co., Ltd.