Clinical trials: Chronic Hypertension
Chronic Disease, Obesity
Active and Healthy Brotherhood: A Program for Chronic Disease Self-Management for Black Men
This study will test ways to improve health behaviors using an intervention that has been specially designed for African-American men.
- Conditions
- Chronic Disease, Obesity, Hypertension, Diabetes
- Trial name
- NCT02362737
- Testing
- Active and Healthy Brotherhood (AHB)
- Where
- United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- Gramercy Research Group
Venous Hypertension Ulcers, Venous Stasis Ulcer
Cooling Leg and Foot Ulcer Skin Post Healing to Prevent Ulcer Recurrence
The goal of this study is to test MUSTCOOL, a home-based self-monitoring and self-management ulcer prevention intervention for patients with newly healed chronic venous leg and diabetic foot ulcers.
- Conditions
- Venous Hypertension Ulcers, Venous Stasis Ulcer, Venous Ulcer, Venous Insufficiency
- Trial name
- MUSTCOOL (NCT02626156)
- Testing
- Cooling gel pack, Cooling cotton pack
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- Medical University of South Carolina
Chronic Thromboembolic Pulmonary Hypertension
Identification of Criteria of the Success of the Endarterectomy in Chronic Pulmonary Post Embolic Hypertension
In order to improve effectiveness of the surgical operation thanks to a reduction in the rate of failure, this study will allow us to identify predictive angiographic and CT finding of surgical failure, starting from standardized…
- Trial name
- ETHAPE (NCT00657722)
- Testing
- Angiography and Computed Tomography
- Where
- 2 sites in France
- Volunteers
- 249 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Kidney Disease, Hypertension
Urinary Uromodulin, Dietary Sodium Intake and Ambulatory Blood Pressure in Patients With Chronic Kidney Disease
In chronic kidney disease (CKD), hypertension is characterized by the phenomenon of sodium-sensitivity, i.e., the disproportionate increase in blood pressure (BP) due to an increase in dietary sodium consumption to maintain…
- Trial name
- NCT06363097
- Where
- Greece
- Volunteers
- 130 people
- Sponsor
- Aristotle University Of Thessaloniki
Hypertension, Peritoneal Dialysis
Blood Pressure Control With Thiazide Diuretics in Peritoneal Dialysis Patients
To evaluate the blood pressure lowering effects of thiazide diuretics in patients on peritoneal dialysis
- Conditions
- Hypertension, Peritoneal Dialysis, End Stage Kidney Disease (ESRD)
- Trial name
- NCT07271420
- Testing
- Hydrochlorothiazide 25mg once per day
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
Chronic Kidney Diseases, Cardiovascular Diseases
Dietary Acid Reduction and Progression of Chronic Kidney Disease
Upon completion, this project will determine if dietary acid reduction done with either fruits and vegetables (F+V) or the medication sodium bicarbonate (NaHCO3) in study participants with high blood pressure (hypertension) and…
- Conditions
- Chronic Kidney Diseases, Cardiovascular Diseases, Hypertension
- Trial name
- NCT06046924
- Testing
- Fruits and vegetables (F+V), NaHCO3 Tablets, Usual Care
- Volunteers
- 153 people
- Sponsor
- Donald Wesson
Chronic Obstructive Pulmonary Disease, Endothelial Dysfunction
Micro-doses of Physical Activity for COPD
Chronic obstructive pulmonary disease (COPD) is a disease of the lungs that makes it hard for people to breath. Those with COPD spend considerably more time sitting and lying and less time performing physical activity than…
- Conditions
- Chronic Obstructive Pulmonary Disease, Endothelial Dysfunction, Vascular Stiffness, Hypertension
- Trial name
- COPD (NCT05553223)
- Testing
- Microdoses of activity
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Uncontrolled Hypertension, Renal Denervation
Renal Denervation in Chronic Kidney Disease - RDN-CKD Study
RDN-CKD Study is a prospective, randomized (1:1, central randomization), double-blind (unblinded interventionalist and blinded study team at each center), sham controlled, multicenter feasibility study.
- Conditions
- Uncontrolled Hypertension, Renal Denervation, Chronic Kidney Disease stage3
- Trial name
- RDN-CKD (NCT04264403)
- Testing
- Renal denervation
- Where
- 4 sites in Germany
- Volunteers
- 44 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Hypertension, Chronic Kidney Disease
Impact of Sympathetic Renal Denervation- a Study in Patients After Renal Transplantation
The study is aiming to document the safety and effectiveness of renal denervation in patients after renal transplantation with hypertension.
- Conditions
- Hypertension, Chronic Kidney Disease, Renal Transplantation, Sympathetic Activity
- Trial name
- ISAR-denerve (NCT01899456)
- Testing
- Catheter-based renal denervation
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- Technical University of Munich
Advanced Chronic Liver Disease, Portal Hypertension Related to Cirrhosis
Program to Avoid NSAIDs in Patients With Advanced Chronic Liver Disease
This study aims to implement measures to avoid the use of NSAIDs or metamizole in patients with advanced chronic liver disease (ACLD) scheduled for major surgery, which are contraindicated due to increased risk of renal…
- Trial name
- NCT07249294
- Testing
- Multidisciplinary support program
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Parc de Salut Mar
Hypertension
Open-label Follow-up Trial of Fixed Dose Combination of Telmisartan + Hydrochlorothiazide in Hypertensive Patients
The primary objective is to assess the efficacy and safety of the fixed dose combination of telmisartan 80 mg + hydrochlorothiazide 25 mg (T80/H25) alone or in addition to other antihypertensive therapies during open-label…
- Trial name
- NCT00267943
- Testing
- telmisartan 80 mg + hydrochlorothiazide 25 mg
- Where
- 78 sites in Denmark, Finland and 14 more
- Volunteers
- 639 people
- Sponsor
- Boehringer Ingelheim
Venous Leg Ulcer (VLU), Venous Hypertension Ulcers
Effect of Photobiomodulation on Healing of Venous Leg Ulcers
Venous leg ulcers are a significant public health problem because of their prolonged duration, high recurrence rates, and economic, social, and quality-of-life effects.
- Conditions
- Venous Leg Ulcer (VLU), Venous Hypertension Ulcers, Chronic Venous Insufficiency, Chronic Venous Disease
- Trial name
- NCT07123285
- Testing
- Photobiomodulation Therapy, Compression Therapy
- Where
- Brazil
- Volunteers
- 102 people
- Sponsor
- University of Nove de Julho
Hypertension
Post-marketing Surveillance for Hypertensive Patients With Diabetes and/or Chronic Kidney Disease
This study is a post-marketing surveillance in Japan, and it is a local prospective, company sponsored and observational study of patient who have been treated by Adalat CR for hypertension with diabetes and/or chronic kidney…
- Trial name
- NCT01363336
- Testing
- Nifedipine (Adalat CR, BAYA1040)
- Where
- Japan
- Volunteers
- 1,882 people
- Sponsor
- Bayer
Hypertension, Pulmonary, Pulmonary Disease, Chronic Obstructive
Chronic Obstructive Pulmonary Disease and Pulmonary Hypertension: Prevalence and Quality of Life
The purpose of this study is to determine the prevalence of pulmonary hypertension (PH) among patients suffering from Chronic Obstructive Pulmonary Disease (COPD) and to assess the quality of life in those patients with…
- Trial name
- NCT01423071
- Where
- Germany
- Volunteers
- 220 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Diabetic Retinopathy, Macular Degeneration
Advancing Understanding of Transportation Options
This Stage II randomized, controlled, longitudinal trial seeks to assess the acceptability, feasibility, and effects of a driving decision aid use among geriatric patients and providers.
- Conditions
- Diabetic Retinopathy, Macular Degeneration, Glaucoma, Retinitis Pigmentosa
- Trial name
- AUTO (NCT04141891)
- Testing
- Driving Decision Aid, Older Drivers Website
- Where
- 3 sites in United States
- Volunteers
- 529 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cardiovascular Diseases, Hypertension
Secondhand Tobacco Smoke and Cardiovascular Disease
This is a double-blind randomized placebo-controlled crossover clinical trial of efficacy and safety of an FDA-approved angiotensin receptor blocker (losartan) to improve cardiopulmonary outcomes in individuals with pre-Chronic…
- Trial name
- NCT04715568
- Testing
- Losartan
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Chronic Thromboembolic Pulmonary Hypertension
Clinical Study to Assess the Safety, Tolerability and Efficacy of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension
Long-term study to evaluate if macitentan is safe, tolerable and efficient enough to be used for treatment of inoperable chronic thromboembolic pulmonary hypertension (CTEPH)
- Trial name
- MERIT-2 (NCT02060721)
- Testing
- Macitentan
- Where
- 33 sites in Belgium, China and 13 more
- Volunteers
- 76 people
- Sponsor
- Actelion
The Geodemographics of CTEPH in Taiwan
Taiwan Cohort - Chronic ThromboEmbolic Pulmonary Hypertension Registry
The diagnosis of chronic thromboembolic pulmonary hypertension (CTEPH) is difficult for numerous reasons and is related with a poor prognosis. In Taiwan, the incidence of CTEPH and its clinical features are unknown.
- Trial name
- NCT03667391
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Renal Insufficiency, Chronic Hypertension
Spironolactone in CKD Enabled by Chlorthalidone: PILOT
Highly prevalent among patients with chronic kidney disease (CKD) and poorly controlled blood pressure (BP), is a modifiable risk factor to abrogate both kidney failure progression and cardiovascular (CV) disease.
- Trial name
- SPICE PILOT (NCT05222191)
- Testing
- Spironolactone, Chlorthalidone
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Indiana Institute for Medical Research
Cardiovascular Kidney Metabolic Syndrome
Cardiovascular-Kidney-Metabolic Syndrome Registry
The goal of this observational registry study is to learn about cardiovascular-kidney-metabolic syndrome, also called CKMS, among adults receiving care at tertiary care hospitals in India.
- Trial name
- CKMS Registry (NCT07718789)
- Volunteers
- 2,250 people
- Sponsor
- Centre for Chronic Disease Control, India
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