Clinical trials: Chronic Hypertension
Hypertension
Oral Cannabidiol Effect on Blood Pressure in Hypertensive Patients
The objective of this randomized, placebo-controlled and crossover study is to extend the findings from the acute studies into more chronic administration of CBD in individuals with mild or moderate hypertension who are either…
- Trial name
- HYPER-H21-4 (NCT05346562)
- Testing
- Cannabidiol
- Where
- Croatia
- Volunteers
- 70 people
- Sponsor
- University of Split, School of Medicine
Obesity, Diabetes
Effectiveness of Patient-centered Community Health Worker Support to Help Patients Control Chronic Disease
The purpose of this proposal is to compare the effectiveness of community health worker (CHW) support vs. usual primary care for helping chronically-ill, low-SES patients to improve control of chronic conditions.
- Conditions
- Obesity, Diabetes, Hypertension, Asthma/COPD With Tobacco Dependence
- Trial name
- NCT01900470
- Testing
- CHW Goal Support
- Where
- United States
- Volunteers
- 302 people
- Sponsor
- University of Pennsylvania
Right Ventricular Failure, Chronic Thromboembolic Pulmonary Hypertension
Right Ventricular Resynchronization Therapy
The purpose of this study is to determine whether cardiac resynchronization therapy with the use of an implanted electronic pacemaker reduces morbidity associated with chronic thromboembolic pulmonary hypertension
- Conditions
- Right Ventricular Failure, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Hypertension
- Trial name
- RVRT (NCT01163422)
- Testing
- Implantation of 3-chamber pacemaker
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pulmonary Hypertension, Pulmonary Arterial Hypertension
Biomarkers in the Evaluation of Chronic Lung Disease
We hypothesize that hypoxia-induced pulmonary vascular remodeling is mediated by macrophage migration inhibitory factor (MIF), that remodeling is in fact the reflection of a chronic inflammatory process, and that MIF may be a…
- Conditions
- Pulmonary Hypertension, Pulmonary Arterial Hypertension, Interstitial Lung Disease
- Trial name
- NCT00926523
- Testing
- Blood Gas, Pulmonary Exercise Test, Spirometry
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Glaucoma, Open-Angle, Glaucoma, Primary Open Angle
Following Patients After Selective and Pascal Laser Trabeculoplasty for Treatment of Chronic Open-Angle Glaucoma
The purpose of this study is to follow and describe the outcomes of patients after selective and pascal laser trabeculoplasty treatment for chronic open-angle glaucoma.
- Conditions
- Glaucoma, Open-Angle, Glaucoma, Primary Open Angle, Exfoliation Glaucoma, Glaucoma, Pigmentary
- Trial name
- FPSPLTTCOAG (NCT02679482)
- Where
- Colombia
- Volunteers
- 36 people
- Sponsor
- Fundación Oftalmológica Nacional
Chronic Kidney Disease, Hypertension
Assessment of Blood Pressure Control and Target Organ Damage in Patients With Chronic Kidney Disease and Hypertension -II
The purpose of this study is to find the change of blood pressure (BP) control pattern (true controlled, white-coat, masked, and sustained uncontrolled/ dipper, non-dipper, reverse-dipper, and extreme-dipper) in patients with…
- Trial name
- NCT02078115
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Seoul National University Hospital
Pulmonary Rehabilitation, Physical Activities
Feasibility of Integrating Street Racket Into Ambulatory Pulmonary Rehabilitation
This study looks at whether Street Racket is a feasable activity that can be added to pulmonary rehabilitation for people with chronic lung disease.
- Conditions
- Pulmonary Rehabilitation, Physical Activities, Exercise Therapy
- Trial name
- APRacket (NCT07430943)
- Testing
- Street Racket
- Where
- 2 sites in Switzerland
- Volunteers
- 12 people
- Sponsor
- Mona Lichtblau
Variceal Bleeding, Ultrasonography
Ultrasound Prediction of Esophageal Variceal Bleeding Risk
This prospective observational study aims to evaluate the accuracy of using routine abdominal ultrasound to predict the risk of esophageal variceal bleeding in adult patients with liver cirrhosis.
- Conditions
- Variceal Bleeding, Ultrasonography, Esophageal Bleeding, Esophageal Varices
- Trial name
- NCT07571876
- Volunteers
- 165 people
- Sponsor
- Assiut University
Atherosclerotic Renal Artery Stenosis, Ischemic Nephropathy
MSC for Occlusive Disease of the Kidney
To determine the safety and toxicity of intra-arterial infused autologous adipose derived mesenchymal stromal (stem) cells in patients with vascular occlusive disease of the kidney.
- Conditions
- Atherosclerotic Renal Artery Stenosis, Ischemic Nephropathy, Renovascular Hypertension
- Trial name
- NCT01840540
- Testing
- Arterial infusion of autologous mesenchymal stem cells
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Hypertension, Depression
Patient-Centred Innovations for Persons With Multimorbidity - Ontario
The aim of Patient-Centred Innovations for Persons With Multimorbidity (PACE in MM) study is to reorient the health care system from a single disease focus to a multimorbidity focus; centre on not only disease but also the…
- Conditions
- Hypertension, Depression, Anxiety, Musculoskeletal Pain
- Trial name
- PACEinMM-ON (NCT02742597)
- Testing
- TIP / IMPACT Plus Care Coordination
- Where
- 9 sites in Canada
- Volunteers
- 175 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Chronic Pulmonary Thromboembolism
Early Detection of CTEPH in Patients After APE
The project is a national, prospective, multicenter, observational pilot project of screening CTEPH in pacients after APE in the Czech Republic.
- Trial name
- CTEPH (NCT06865326)
- Testing
- Standardized CTEPH Screening Protocol
- Where
- 10 sites in Czechia
- Volunteers
- 500 people
- Sponsor
- Institute of Health Information and Statistics of the Czech Republic
Coronary Disease, Stroke
Assessing Outcomes of Enhanced Chronic Disease Care Through Patient Education and a Value-based Formulary Study
The purpose of this study is to determine the effect of two novel interventions; (1) a value-based formulary which eliminates copayment for selected high-value medications (proven to prevent heart attacks, stroke, and…
- Conditions
- Coronary Disease, Stroke, Chronic Kidney Disease, Heart Failure
- Trial name
- ACCESS (NCT02579655)
- Testing
- Copayment Elimination, Personalized Education
- Where
- Canada
- Volunteers
- 4,764 people
- Sponsor
- University of Calgary
Advanced Chronic Liver Disease, Surgery--Complications
Non-invasive Methods and Surgical Risk Stratification in Cirrhotics Undergoing Elective Extrahepatic Surgery
The ELASTO-SURGERY study aims to evaluate the prognostic role of portal hypertension evaluated by non-invasive methods in predicting post-operative morbidity (at 90 days) and mortality (at 365 days) in patients with advanced…
- Trial name
- NCT04615091
- Where
- 37 sites in United States, Austria and 10 more
- Volunteers
- 250 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Chronic Kidney Disease
Veteran Centered Meal Intervention in Chronic Kidney Disease
This study will study if medically tailored meals can improve health and well-being among Veterans with kidney disease. Participants will be randomly assigned to receive either medically tailored meals or usual care (wait-list…
- Trial name
- VETCKD (NCT07793591)
- Testing
- Medically tailored meals (MTMs)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- VA Office of Research and Development
Portal Hypertension, Chronic Liver Disease
EUS vs TJ for Liver Biopsy and Portal Pressure Gradient Measurement
This study will directly compare the endoscopic ultrasound guided approach to obtain adequate liver biopsies and portal pressure gradient measurements to the current standard of care which uses the transjugular approach.
- Conditions
- Portal Hypertension, Chronic Liver Disease, Cirrhosis
- Trial name
- NCT05118308
- Testing
- Transjugular hepatic venous pressure gradient measurement with liver biopsy, Endoscopic ultrasound portal pressure gradient measurement with liver biopsy
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Obesity, Hyperlipidemias
Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients
Developed nations worldwide are currently enduring a health crisis, as chronic diseases continue to decrease quality of life and promote additional disease states or even death for much of the population.
- Conditions
- Obesity, Hyperlipidemias, Polycystic Ovary Syndrome, Hypertension
- Trial name
- NCT06049420
- Testing
- Lifestyle counseling and coaching
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- West Virginia School of Osteopathic Medicine
Portal Hypertension
Non-Invasive Portal and Hepatic Vein Pressure Estimation
Background Portal hypertension (PH) is a spectrum of complications of end-stage liver disease (ESLD) and cirrhosis, with severe manifestations including ascites and gastroesophageal varices.
- Trial name
- NONEEDLES (NCT06210178)
- Testing
- Magnetic Resonance Imaging
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Leiden University Medical Center
Patient Readmission, Pulmonary Disease, Chronic Obstructive
UM CRMC RecuR Score Pilot
This study will look to implement a plan for enhanced transitional care for patients at high risk of unplanned hospital readmission in hopes of reducing their risk for readmission in the first 30 days post discharge from an…
- Conditions
- Patient Readmission, Pulmonary Disease, Chronic Obstructive, Heart Failure, Diabetes Mellitus Poor Control
- Trial name
- NCT05765903
- Testing
- Standard of Care, Enhanced Care
- Where
- United States
- Sponsor
- University of Maryland, Baltimore
Chronic Hypertension
To Determine Blood Pressure Interaction Between TC-5214 and Anti-Hypertensive Medications (Calcium Channel Blockers, Beta Blockers, and ACE Inhibitors) in Patients With Chronic Hypertension
This is a two part study. Part 1 will determine determine if administration of TC-5214 has an effect on sitting blood pressure in patients with chronic hypertension.
- Trial name
- NCT01403922
- Testing
- TC-5214
- Where
- 4 sites in United States, Germany and 1 more
- Volunteers
- 80 people
- Sponsor
- AstraZeneca
COPD, Hypertension
Sleepiz One+ Versus Capnography and Electrocardiography
EtCO2, or exhaled carbon dioxide, is a non-invasive and commonly used measure for respiratory rate and function. It can be easily monitored using a device called a capnograph, which consists of a sensor that is placed near the…
- Conditions
- COPD, Hypertension, Sleep Apnea, Asthma
- Trial name
- SPZCAP (NCT05712226)
- Testing
- Sleepiz One+
- Where
- Switzerland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sleepiz AG
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