Clinical trials: Chronic Hypertension
Chronic Kidney Disease, Hypertension
Group-based Chronic Kidney Disease Care
A two-group randomized clinical trial testing whether group-based care is feasible and will help improve blood pressure control in adult and adolescent patients with chronic kidney disease and hypertension.
- Trial name
- NCT02467894
- Testing
- Group-based Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Albert Einstein College of Medicine
Overweight, Obesity
Individual Factors Related to Chronic Low-grade Inflammation and Cardiometabolic Disease Risk
The goal of this observational study is to learn about low-grade inflammation in healthy individuals and individuals with overweight or obesity.
- Conditions
- Overweight, Obesity, Metabolic Syndrome, Healthy
- Trial name
- PINEAPPL (NCT06355544)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Integrative Phenomics
COVID-19, Chronic Liver Failure
Evaluation of Long Haul COVID-19 and Vaccine Immunogenicity in Patients With Liver Disease
The project is essential to understand the impact of the COVID-19 pandemic in patients with Chronic Liver Disease (CLD). The impact has been felt due to direct risk of COVID infection in self, or in caregivers, lack of access to…
- Conditions
- COVID-19, Chronic Liver Failure, Cirrhosis, Liver, Portal Hypertension
- Trial name
- EvaLongCovid (NCT05107271)
- Testing
- COVID-19 serosurvey
- Where
- India
- Volunteers
- 252 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pulmonary Hypertension
Acute Effects of rhBNP in Patients With PH Associated With Acute Exacerbation of Chronic Pulmonary Disease
To evaluate the acute effect of recombinant human brain natriuretic peptide(rhBNP) on pulmonary hypertension of acute exacerbations of chronic pulmonary disease.
- Trial name
- NCT02742909
- Testing
- rhBNP
- Where
- China
- Volunteers
- 9 people
- Sponsor
- LI ZHAO
Chronic Venous Hypertension Due to Deep Vein Thrombosis, Venous Reflux
The ATLANTIS Trial
The purpose of this study is to test whether addition of aquatic exercise to conventional treatment helps reduce the adverse outcomes of chronic venous insufficiency including CVI resulting from venous thrombosis.
- Trial name
- ATLANTIS (NCT02553720)
- Testing
- exercise in water, aquatic activity plus conventional management
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- Arizona Cardiovascular Consultants
Pre-Eclampsia, Gestational Hypertension
The Effect of Foot Massage on Blood Pressure and Anxiety Levels in Pregnants With Hypertension
This research was conducted as a prospective, experimental and randomised controlled research to determine the effect of foot massage applied to pregnant women with hypertension on blood pressure and anxiety levels.
- Conditions
- Pre-Eclampsia, Gestational Hypertension, Chronic Hypertension With Pre-Eclampsia, Superimposed Pre-Eclampsia
- Trial name
- NCT05542654
- Testing
- Foot Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bandırma Onyedi Eylül University
Chronic Kidney Diseases
Effects of a Whole-food, Plant-based Nutrition Program on BP and Potassium in Subjects With CKD
The purpose of this study is to determine if an educational program emphasizing a whole food plant based diet favorably impacts blood pressure while not significantly increasing blood potassium levels, by comparing a group of…
- Trial name
- NCT06343129
- Testing
- Dietary education program
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- University of Rochester
Chronic Obstructive Pulmonary Disease, Pulmonary Hypertension
Sildenafil Effects on Pulmonary Haemodynamics and Gas Exchange in Chronic Obstructive Pulmonary Disease (COPD)
Sildenafil is a phosphodiesterase-5 inhibitor that has been approved for the treatment of pulmonary arterial hypertension with orphan drug designation. Sildenafil modulates the nitric oxide (NO) pathway in the vessel wall.
- Trial name
- SIL-COPD-01 (NCT00491803)
- Testing
- Sildenafil
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Hospital Clinic of Barcelona
COPD, Pulmonary Emphysema
ELVR in PH Patients With Severe Emphysema
The purpose of this study is to investigate the effect of endoscopic valve implantation in patients with COPD and PH on hemodynamics, symptoms, exercise tolerance and quality of life in 10 patients in a prospective study.
- Trial name
- NCT01393379
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Heidelberg University
Pulmonary Disease, Chronic Obstructive, Hypertension, Pulmonary
Aerobic Interval Training in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Hypoxemia
Patients with severe Chronic Obstructive Pulmonary Disease (COPD) and low oxygen levels in the blood are at risk of developing pulmonary hypertension and strain on the right side of the heart, both of which are known to increase…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Hypertension, Pulmonary, Hypoxia
- Trial name
- NCT03092622
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 16 people
- Sponsor
- Norwegian University of Science and Technology
Chronic Thromboembolic Pulmonary Hypertension, Residual Pulmonary Hypertension
Continuous Remote Haemodynamic Monitoring With CardioMEMS™ Following Pulmonary Endarterectomy in Chronic Thromboembolic Pulmonary Hypertension:
Chronic thromboembolic pulmonary hypertension (CTEPH) is potentially curable by pulmonary endarterectomy (PEA), although a substantial proportion of patients develop residual pulmonary hypertension despite successful surgery.
- Trial name
- CARDIOMEMSCTPH (NCT07758179)
- Testing
- CardioMEMS
- Volunteers
- 30 people
- Sponsor
- Hospital Universitario 12 de Octubre
Chronic Kidney Disease
Managing Chronic Kidney Disease in Eastern North Carolina
The purpose of this program is to educate primary care physicians in four underserved clinics in eastern North Carolina about chronic kidney disease.
- Trial name
- NCT01054066
- Testing
- Chronic Kidney Disease Education
- Where
- United States
- Volunteers
- 1,257 people
- Sponsor
- East Carolina University
Chronic Thromboembolic Pulmonary Hypertension
Optimized Management After Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Hypertension
Balloon pulmonary angioplasty (BPA) is a new method of treatment for inoperable chronic thromboembolic pulmonary hypertension (CTEPH) or persistent CTEPH after surgery.
- Trial name
- POpPART (NCT04777448)
- Testing
- telerehabilitation
- Volunteers
- 54 people
- Sponsor
- University Hospital, Grenoble
Arterial Hypertension, Chronic Heart Failure
Investigator Initiated Randomized Open-label Comparative Study of Britomar (Prolonged Release Torasemide) and Diuver (Torasemide) to Assess Effects on Natriuresis and Central Hemodynamics.
Study hypothesis is that the time from randomization to the increase of natriuresis (%), time to standardization of natriuresis daily profile, blood pressure profile and the percentage reduction of central hemodynamic parameters…
- Trial name
- NCT02087332
- Testing
- Prolonged release Torasemide (Britomar), Torasemide (Diuver)
- Volunteers
- 78 people
- Sponsor
- Society of Specialists in Heart Failure
Uncontrolled Hypertension, Chronic Kidney Diseases
A Study to Evaluate CIN-107 for the Treatment of Patients With Uncontrolled Hypertension and Chronic Kidney Disease
This study will evaluate the efficacy and safety of CIN-107 for the treatment of hypertension in patients with uncontrolled hypertension (uHTN) and Chronic Kidney Disease (CKD).
- Trial name
- NCT05432167
- Testing
- CIN-107
- Where
- 71 sites in United States
- Volunteers
- 195 people
- Sponsor
- AstraZeneca
Hypertension in Pregnancy
Chronic Hypertension and Pregnancy 2 (CHAP2) Pilot Project
The CHAP2 study is designed to provide preliminary data for a larger multicenter study to assess whether treatment of stage 1 hypertension (HTN) in pregnancy improves maternal and or neonatal outcomes.
- Trial name
- CHAP2 (NCT05989581)
- Testing
- Labetalol or Nifedipine
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Hypertension, Mediterranean Diet
Mediterranean Diet And Blood Pressure In Hypertension
An experimental randomized controlled trial was conducted to evaluate the effects of Mediterranean diet education on blood pressure levels and quality of life in hypertensive patients.
- Conditions
- Hypertension, Mediterranean Diet, Quality of Life
- Trial name
- NCT07106567
- Testing
- Mediterranean diet education, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Uludag University
Non-operable Chronic Thromboembolic Pulmonary Hypertension
Efficacy and Tolerability of Subcutaneously Administered Treprostinil Sodium in Patients With Severe (Non-operable) Chronic Thromboembolic Pulmonary Hypertension (CTREPH)
The primary purpose of this study is to determine the effect on six-minute walking test (6MWT) distance after 24 weeks treatment with subcutaneous (SC) Treprostinil Sodium in patients with Severe (inoperable) Chronic…
- Trial name
- CTREPH (NCT01416636)
- Testing
- Treprostinil sodium
- Where
- 6 sites in Austria, Czechia and 2 more
- Volunteers
- 105 people
- Sponsor
- SciPharm SàRL
Hypertension in Dialysis Patients
Sodium Bicarbonate in Intra-dialytic Hypertension in Chronic Hemodialysis Patients
The study is designed to diminish intra-dialytic hypertension in chrnic hemodialysis patients suffering from metabolic acidosis (low bicarbonate levels).
- Trial name
- NCT07231900
- Testing
- Sodium Bicarbonate (NaHCO3)
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Assaf-Harofeh Medical Center
Depressive Episode, Chronic Ischaemic Heart Disease
Increasing the Efficiency of Depression-screening Using Patient-targeted Feedback
Out-patients with coronary heart disease or hypertension will fill out a depression screening questionnaire while waiting in a cardiac clinic.
- Conditions
- Depressive Episode, Chronic Ischaemic Heart Disease, Hypertension
- Trial name
- DEPSCREEN-INFO (NCT01879111)
- Testing
- patient-targeted feedback
- Where
- 2 sites in Germany
- Volunteers
- 4,151 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
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