Clinical trials: Chronic Hypertension
Chronic Thromboembolic Pulmonary Hypertension, Chronic Thromboembolic Disease
Chronic Thromboembolic Disease Registry
The goal of this patient registry is to learn about the natural history in patients with chronic thromboembolic disease (CTD) and/or chronic thromboembolic pulmonary hypertension (CTEPH).
- Trial name
- NCT05843500
- Testing
- Survey
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Hypertension, Dyslipidemias
Exploring the Effects of Antihypertensive and Lipid-Lowering Drugs on Inflammatory Cytokine Levels
This study investigates the causal relationships between antihypertensive and lipid-lowering drugs and inflammatory cytokines using a drug-targeted Mendelian randomization approach.
- Conditions
- Hypertension, Dyslipidemias, Inflammatory Response, Chronic Inflammation
- Trial name
- MRDLT (NCT06622304)
- Where
- China
- Volunteers
- 250,736 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Comparative Effectiveness of Telemedicine in Primary Care
Leveraging a natural experiment approach, the investigators will examine rapidly changing telemedicine and in-person models of care during and after the COVID-19 crisis to determine whether certain patients could safely choose to…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease (COPD), Congestive Heart Failure, Diabetes
- Trial name
- NCT04684836
- Testing
- Exposure to telemedicine, after the onset of the pandemic
- Where
- 4 sites in United States
- Volunteers
- 33,100 people
- Sponsor
- Weill Medical College of Cornell University
End Stage Renal Disease, Hypertension, Renal
Efficacy of L-methylfolate and Methylcobalamine in Treating Resistant Hypertension Associated With Elevated Serum Homocysteine in Hemodialysis Patients.
The aim of the study is to evaluate the efficacy of L-methylfolate in combination with methylcobalamine in reducing homocysteine blood levels in hypertensive end-stage renal disease patients on regular hemodialysis and its…
- Trial name
- NCT05807711
- Testing
- L-Methyl Folate and methylcobalamine
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Alexandria University
Chronic Kidney Diseases, Hyperkalemia
Potassium Correction for RAAS Optimization in Chronic Kidney Disease
The goal of this placebo-controlled, double-blinded cross-over trial is to test whether patiromer, compared with placebo, better enables up-titration of RAAS-blocker treatment in patients with chronic kidney disease stage 3b/4.
- Conditions
- Chronic Kidney Diseases, Hyperkalemia, Hypertension
- Trial name
- PROMISE (NCT06256991)
- Testing
- Patiromer 8400 MG [Veltassa]
- Where
- Netherlands
- Volunteers
- 44 people
- Sponsor
- University Medical Center Groningen
Chronic Thromboembolic Pulmonary Hypertension
Balloon Pulmonary Angioplasty vs. Combined Approach With Pulmonary Artery Denervation in CTEPH: Effectiveness Comparison
This clinical trial investigates new treatment approaches for chronic thromboembolic pulmonary hypertension (CTEPH), a condition affecting the lungs' blood vessels.
- Trial name
- BPA-PADN (NCT06209710)
- Testing
- Balloon Pulmonary Angioplasty combined with Pulmonary Artery Denervation
- Where
- Serbia
- Volunteers
- 20 people
- Sponsor
- Boris Dzudovic
Chronic Kidney Diseases, Hypertension
Interactive Computer-adaptive Chronic Kidney Disease Education Program
The goal of this pilot clinical trial is to evaluate a culturally tailored computerized education program in hospitalized African-American patients with advanced chronic kidney disease (CKD).
- Trial name
- ICCKD (NCT06364358)
- Testing
- Computerized CKD Education, Usual Hospital Care
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Chicago
Hypertension, Diabetes
Developing Accessible Telehealth Programs for Diabetes and Hypertension Management in Bolivia
The purpose of the study is to evaluate the feasibility and impact of an automated phone system in monitoring and improving self-care and health outcomes among patients with diabetes and/or hypertension in Bolivia, in addition to…
- Trial name
- NCT02429297
- Testing
- HITCM-only, HITCM+CP
- Where
- Bolivia
- Volunteers
- 110 people
- Sponsor
- University of Michigan
Hypertension
DIALYSATE SODIUM CONCENTRATION AND BLOOD PRESSURE IN CHRONIC HEMODIALYSIS PATIENTS
While hypertension is one of the most common causes of end-stage renal disease, it is also present in the vast majority of hemodialysis patients.
- Trial name
- NCT06547697
- Testing
- Dialysate sodium concentration
- Volunteers
- 45 people
- Sponsor
- University Medical Centre Maribor
Congenital Diaphragmatic Hernia
Preliminary Study of Pediatric Diaphragmatic Elastography
This diaphragmatic elastography study is a preliminary pilot study to have first values of diaphragmatic stiffness in patients with a history of diaphragmatic hernia and to estimate the difference in stiffness compared to a group…
- Trial name
- ECHODIA (NCT06666140)
- Testing
- Ultrasonic elastography
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Strasbourg, France
Depression, Diabetes
Effectiveness of a mHealth Intervention for the Treatment of Depression in People With Diabetes or Hypertension in Peru
Background: Depression is a common comorbidity of physical chronic diseases such as diabetes and/or hypertension and constitutes an important public health problem.
- Conditions
- Depression, Diabetes, Hypertension
- Trial name
- LATIN-MHPeru (NCT03026426)
- Testing
- CONEMO
- Where
- 8 sites in Peru
- Volunteers
- 432 people
- Sponsor
- Universidad Peruana Cayetano Heredia
Uncontrolled Hypertension
Effect of the MobiusHD® in Renal Hemodialysis Subjects With Uncontrolled Hypertension
This is a prospective, multi-center, open-label clinical trial intended to evaluate the safety and benefit of the MobiusHD® system in renal hemodialysis subjects with uncontrolled hypertension.
- Trial name
- HD (NCT05352425)
- Testing
- MobiusHD
- Sponsor
- Vascular Dynamics, Inc.
Kidney Transplant, Familial Hypercholesterolaemia
Cardiovascular Risk in Children With Chronic Conditions Study
Children living with chronic health conditions face a higher risk of developing cardiovascular diseases than their peers, largely due to the accelerated aging of the heart and blood vessels.
- Conditions
- Kidney Transplant, Familial Hypercholesterolaemia, Type 1 Diabetes Mellitus (T1DM), Type 2 Diabetes Mellitus (T2DM)
- Trial name
- CR3C (NCT07086989)
- Where
- 3 sites in Hungary
- Volunteers
- 300 people
- Sponsor
- Semmelweis University
Chronic Conditions, Multiple
Implications of Stress Management Program
Previous studies indicated that patients with diabetes mellitus and hypertension had higher level of perceived stress, used maladaptive coping strategies and poor health-related quality of life.
- Trial name
- NCT04978974
- Testing
- Stress Management Program
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- University of Gujrat
Chronic Kidney Diseases
miRNA in Chronic Kidney Diseases
Oxidative stress and endoplasmic reticulum (ER) stress play a key role in tubular damage in both acute kidney injury and chronic kidney disease (CKD).
- Trial name
- NCT06316284
- Where
- Croatia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Hypertension
The Effect of the Patient Activation Measure on Chronic Care
We will test - in a chronically ill managed long term care population - the effectiveness of an intervention that provides nurse Care Managers with an inventory of evidence-based practices tailored to patients with different…
- Trial name
- NCT00299468
- Testing
- Patient Activation Measure Intervention Package
- Where
- United States
- Volunteers
- 283 people
- Sponsor
- Weill Medical College of Cornell University
Chronic Thromboembolic Pulmonary Hypertension
Hemodynamic Effects of BPA at Rest and During Exercise in CTEPH
Chronic thromboembolic pulmonary hypertension (CTEPH) is characterized by obstruction of the pulmonary vasculature by residual organized thrombi, leading to increased pulmonary vascular resistance (PVR), progressive pulmonary…
- Trial name
- EXPERT-BPA (NCT04052243)
- Testing
- Invasive exercise testing
- Where
- 3 sites in Denmark, Japan and 1 more
- Volunteers
- 80 people
- Sponsor
- Aarhus University Hospital
Hypertension, Chronic Kidney Disease
Renal Sympathetic Denervation in Moderate to Severe Chronic Kidney Disease
A pilot, single-center, prospective, interventional study. The objective is to demonstrate that catheter-based renal denervation using carbon dioxide renal angiography in patients with moderate to severe chronic kidney disease…
- Trial name
- NCT02863510
- Testing
- Renal Sympathetic Denervation
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Heart of England NHS Trust
Renal Insufficiency, Chronic, Glaucoma
Intraocular Pressure and Hemodialysis Midwestern Brazil
Objective: To evaluate the variation in intraocular pressure in patients with chronic kidney disease, according to the time interval between hemodialysis sessions and to the influence of weight and blood pressure on intraocular…
- Trial name
- EHPIOBRAZIL (NCT02405884)
- Testing
- Kowa HA-2 Perkins applanation tonometer.
- Volunteers
- 39 people
- Sponsor
- VER Excelência em Oftalmologia
Chronic Obstructive Pulmonary Disease, Pulmonary Hypertension
Effects of Ventavis in Patients With Pulmonary Hypertension (PH) Secondary to Chronic Obstructive Pulmonary Disease (COPD)
This is a phase 2, Multi-center, double-blind, randomized, placebo-controlled study to evaluate the effects of inhaled Iloprost in patients with pulmonary hypertension secondary to COPD.
- Trial name
- NCT01437878
- Testing
- Iloprost
- Where
- 11 sites in United States, France and 1 more
- Volunteers
- 2 people
- Sponsor
- Actelion
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