Clinical trials: Chronic Interstitial Cystitis
Interstitial Cystitis
Peppermint Oil for the Treatment of Interstitial Cystitis / Bladder Pain Syndrome
The purpose of this study is to assess the use of peppermint oil as a treatment for Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS).
- Trial name
- NCT04845217
- Testing
- Peppermint oil, Coconut Oil
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Interstitial Cystitis Bladder Pain Syndromes
PTNS Versus Sham Efficacy in Treatment of BPS
This is a prospective, single center, double-blind, randomized, controlled trial comparing the efficacy of percutaneous tibial nerve stimulation to sham in the treatment of Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC)…
- Trial name
- NCT02747420
- Testing
- NURO TM
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Painful Bladder Syndrome, Interstitial Cystitis
Botox as a Treatment for Interstitial Cystitis in Women
Patients with interstitial cystitis have been well documented to have pelvic floor muscle tenderness as well as pain on bladder distension.
- Trial name
- NCT00194610
- Testing
- Botox, normal saline
- Volunteers
- 20 people
- Sponsor
- University of Washington
Urinary Tract Infections, Prostatitis
Rapid Molecular Organism Identification and Mixed Flora Antibiotic Resistance Profiling (MixAR) Prospective Study
In this protocol, investigators are examining the ability for a novel multiplex PCR assay with mixed floral antibiotic resistance profiling is safe and increases effective treatment for urinary tract infections in a urology…
- Conditions
- Urinary Tract Infections, Prostatitis, Interstitial Cystitis
- Trial name
- RapIDMixAR (NCT03931538)
- Testing
- Guidance 4.0 PCR test, Urine Culture
- Where
- United States
- Volunteers
- 2,511 people
- Sponsor
- Pathnostics
Interstitial Cystitis, Bladder Pain Syndrome
Assessment of Urinary Polymerase Chain Reaction (PCR) and Next Generation Sequencing (NGS) Technology in the Evaluation and Management of Females With Chronic Bladder Pain and Cystitis-like Symptoms
Real-world clinical practice multicenter study to determine the clinical implications of employing PCR/NGS technology to identify and treat potential urinary pathogens in female participants identified with bladder pain and/or…
- Trial name
- NCT05276466
- Testing
- Polymerase Chain Reaction and Next-Generation DNA Sequencing
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- MicroGenDX
Healthy
Safety and Tolerability Study of the Taris Placebo System
The aim of this protocol is to evaluate the tolerability of the Taris placebo system for the development program and to provide key safety and tolerability data for the Taris platform.
- Trial name
- NCT01051336
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- TARIS Biomedical, Inc.
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Interstitial Cystitis, Bladder Pain Syndrome
Platelet Enriched Plasma for Treatment of Interstitial Cystitis
A prospective randomized trial will be conducted aiming at evaluation the efficacy and safety of platelet enriched plasma for management of bladder pain syndrome .
- Conditions
- Interstitial Cystitis, Bladder Pain Syndrome, Platelet Enriched Plasma
- Trial name
- NCT04118946
- Testing
- platelet enriched plasma
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Mansoura University
Interstitial Cystitis
Autonomic Response During Cystodistension in Patients Suspected of Having Interstitial Cystitis
The aim of this study is to check whether patients with cystoscopic findings supporting the diagnosis of Interstitial Cystitis (IC) have a higher autonomic response (change in blood pressure / pulse)than patients without…
- Trial name
- NCT01301365
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Assaf-Harofeh Medical Center
Interstitial Cystitis, Painful Bladder Syndrome
Physical Therapy in Women With Interstitial Cystitis
There are many different treatments that doctors recommend for patients with IC/PBS. Only a few research studies have been done to evaluate treatments given to patients.
- Trial name
- IC03 (NCT00733603)
- Testing
- Global Therapeutic Massages (GTM), Myofascial Tissue Manipulation (MTM)
- Where
- 11 sites in United States, Canada
- Volunteers
- 81 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Interstitial Cystitis, Bladder Pain Syndrome
The Female Microbiome in Patients Undergoing Bladder Instillation Therapy
The underlying pathophysiology for BPS/IC is currently an active area of research. There is speculation that there may be alteration in the bladder and vaginal microbiome that contributes to the symptomatology of BPS/IC, however…
- Conditions
- Interstitial Cystitis, Bladder Pain Syndrome, Microbial Colonization
- Trial name
- NCT05414305
- Testing
- Heparin & Alkalinized Lidocaine Bladder Instillation
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Walter Reed National Military Medical Center
Interstitial Cystitis
Observational Study of Hunner's Ulcer in Patient With Interstitial Cystitis/Bladder Pain Syndrome
The purpose of this study is to observe change of distribution pattern of Hunner's ulcer in patient with interstitial cystitis/bladder pain syndrome
- Trial name
- NCT02150811
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Asan Medical Center
Interstitial Cystitis, Bladder Pain Syndrome
Safety, Efficacy, and Frequency of Administration of VNX001 in the Treatment of Interstitial Cystitis / Bladder Pain Syndrome (IC/BPS)
This is an open-label study that will enroll participants with Interstitial Cystitis / Bladder Pain Syndrome (IC/BPS). The study will assess PRN (as needed) dosing of up to 6 intravesical (via catheter) doses of VNX001 (study…
- Trial name
- NCT06394830
- Testing
- VNX001
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- Vaneltix Pharma, Inc.
Prostatitis, Chronic Prostatitis
Microbiome of Urologic Chronic Pelvic Pain Syndrome
This research is being done to learn more about the bacteria that live in the genito-urinary tract in subjects with urologic chronic pelvic pain syndrome (UCPPS).
- Conditions
- Prostatitis, Chronic Prostatitis, Interstitial Cystitis, Painful Bladder Syndrome
- Trial name
- NCT03027076
- Testing
- Genitourinary Specimen Collection, Collect midstream urine samples
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Painful Bladder Syndrome (PBS), Interstitial Cystitis
Submucosal Intravesical Injection of Platelet-rich Plasma in the Treatment of Painful Bladder Syndrome
Interstitial cystitis/painful bladder syndrome (IC/PBS) is characterized by a constellation of bladder symptoms, including urinary frequency, urgency, nocturia, and pelvic pain.
- Trial name
- PRP (NCT06209008)
- Testing
- Intravesical injection of Platlet Rich Plasma (PRP)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Fibromyalgia, Irritable Bowel Syndrome
Observational Study of Control Participants for the MAPP Research Network
The Control Study for the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network has been established to focus on a broader approach to the study of Interstitial Cystitis (IC)/Painful Bladder…
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Fatigue Syndrome, Chronic
- Trial name
- MAPP-Control (NCT01098292)
- Where
- 8 sites in United States
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Interstitial Cystitis
Interstitial Cystitis and Urinary pH
This is a pilot study to assess the correlation between urinary pH and Interstitial Cystitis (IC) pain, with emphasis placed on exploring the type and severity of pain.
- Trial name
- NCT03024619
- Testing
- Pain and Urinary pH
- Volunteers
- 20 people
- Sponsor
- St. Louis University
Interstitial Cystitis
Acupuncture for the Treatment of Interstitial Cystitis (IC) Symptoms
Acupuncture is a form of Chinese medicine that has been in existence for more than a thousand years. This clinical trial performs two types of acupuncture on traditional 'bladder' points to determine if one type demonstrates…
- Trial name
- NCT00094874
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Mary Elizabeth Groff Surgical Medical Research and Education Charitable Trust
Interstitial Cystitis
Cyclosporine in Interstitial Cystitis: Efficacy, Safety and Mechanism of Action
This is a study for patients that have a condition called Interstitial Cystitis, also known as Painful Bladder Syndrome. Patients would have tried at least two different therapies, unsuccessfully,(eg.
- Trial name
- CIC (NCT01990898)
- Testing
- Cyclosporine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- The Cleveland Clinic
Interstitial Cystitis, Recurrent Cystitis
Evaluating the Efficacy and Patient Experience of Catheter-Free Intravesical Instillation
This study aims to evaluate a catheter-free method for delivering medications directly into the bladder, known as intravesical instillation, which is commonly used to treat conditions such as interstitial cystitis/bladder pain…
- Conditions
- Interstitial Cystitis, Recurrent Cystitis, Haemorrhagic Cystitis, Bladder Cancer
- Trial name
- NOCATIN (NCT06719232)
- Testing
- Catheter-Free Intravesical Instillation with a special syringe adapter
- Where
- 2 sites in Hungary
- Volunteers
- 300 people
- Sponsor
- Jahn Ferenc South Pest Teaching Hospital