Clinical trials: Chronic Interstitial Cystitis
Interstitial Cystitis, Painful Bladder Syndrome
Efficacy and Safety Study of Uracyst to Treat Interstitial Cystitis/Painful Bladder Syndrome
A new device for interstitial cystitis is compared to inactive control to determine if it is safe and effective. The study lasts approximately 7 weeks with a 19-week follow-up period.
- Trial name
- NCT00919113
- Testing
- 2% sodium chondroitin sulfate
- Where
- 20 sites in United States
- Volunteers
- 98 people
- Sponsor
- Watson Pharmaceuticals
Bladder Pain Syndrome, Interstitial Cystitis
Low-dose Naltrexone for Bladder Pain Syndrome
Interstitial cystitis/Bladder Pain Syndrome (IC/PBS) is a constellation of symptoms of pelvic discomfort that includes both bladder-related pain as well as urinary frequency, urgency, and nocturia in the absence of an…
- Trial name
- NCT04450316
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Stanford University
Interstitial Cystitis Bladder Pain Syndromes
PTNS Versus Sham Efficacy in Treatment of BPS
This is a prospective, single center, double-blind, randomized, controlled trial comparing the efficacy of percutaneous tibial nerve stimulation to sham in the treatment of Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC)…
- Trial name
- NCT02747420
- Testing
- NURO TM
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Painful Bladder Syndrome, Interstitial Cystitis
Botox as a Treatment for Interstitial Cystitis in Women
Patients with interstitial cystitis have been well documented to have pelvic floor muscle tenderness as well as pain on bladder distension.
- Trial name
- NCT00194610
- Testing
- Botox, normal saline
- Volunteers
- 20 people
- Sponsor
- University of Washington
Interstitial Cystitis
Cyclosporine in Interstitial Cystitis: Efficacy, Safety and Mechanism of Action
This is a study for patients that have a condition called Interstitial Cystitis, also known as Painful Bladder Syndrome. Patients would have tried at least two different therapies, unsuccessfully,(eg.
- Trial name
- CIC (NCT01990898)
- Testing
- Cyclosporine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- The Cleveland Clinic
Cystitis, Interstitial, Ulcer
A Safety and Efficacy Study of LiRIS® in Females With Interstitial Cystitis With Hunner's Lesions
This is a safety and efficacy study of LiRIS® in females with interstitial cystitis with Hunner's lesions.
- Trial name
- NCT02395042
- Testing
- LiRIS®
- Where
- 19 sites in United States, Canada
- Volunteers
- 59 people
- Sponsor
- Allergan
Interstitial Cystitis, Chronic Interstitial Cystitis
PEMF Therapy to Treat Interstitial Cystitis/Bladder Pain Syndrome
The purpose of this study is to gather information from the investigation of a non-pharmacological (non-drug) treatment known as low frequency pulsed electromagnetic field (PEMF).
- Conditions
- Interstitial Cystitis, Chronic Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT04540887
- Testing
- Pulsed Electromagnetic Field (PEMF) Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Interstitial Cystitis/Bladder Pain Syndrome
Study of V117957 in Interstitial Cystitis/Bladder Pain Syndrome
The purpose of this study is to evaluate the safety, tolerability and efficacy of V117957 in subjects with interstitial cystitis/bladder pain syndrome, compared to placebo.
- Trial name
- NCT06285214
- Testing
- V117957
- Where
- 24 sites in United States
- Volunteers
- 47 people
- Sponsor
- Imbrium Therapeutics
Interstitial Cystitis
Usefulness of Dexmedetomidine on Post-operative Pain Management in Patients With Interstitial Cystitis
The purpose of this study is to assess the effects of dexmedetomidine while patients undergo treatment for Interstitial Cystitis (IC).
- Trial name
- NCT01195116
- Testing
- Dexmedetomidine, Normal Saline
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Rochester
Bladder Diseases, Interstitial Cystitis
Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS)
This is a randomized clinical trial study to test the efficacy and safety of amitriptyline in the treatment of patients newly diagnosed with painful bladder syndrome (PBS).
- Trial name
- IC01 (NCT00124306)
- Testing
- Amitriptyline
- Where
- 10 sites in United States, Canada
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Interstitial Cystitis
A Safety, Tolerability and Preliminary Efficacy Study of LiRIS® 400 mg in Women With Interstitial Cystitis (IC) and Hunner's Lesions
The purpose of the study is to evaluate if LiRIS 400 mg is safe and tolerable when administered to women with Interstitial Cystitis with Hunner's lesions, and to evaluate any change in the bladder or in IC symptoms, following…
- Trial name
- NCT01879683
- Testing
- LiRIS® 400 mg
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Allergan
Painful Bladder Syndrome, Interstitial Cystitis
Acupuncture for Female IC/PBSyndrome and Its Effect on the Urinary Microbiome: A Randomized Controlled Trial
The investigators central hypothesis is that women with Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS) will benefit from acupuncture compared with sham treatment and acupuncture responders will have a differential…
- Trial name
- NCT02232282
- Testing
- standard acupuncture treatment
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Loyola University
Interstitial Cystitis
Prospective Trial Comparing Response to Hyperbaric Oxygen Treatment in Patients With Interstitial Cystitis
To review the results of Hyperbaric Oxygen therapy (HBOT) on the symptoms of interstitial cystitis (IC). To determine if there is greater symptom improvement in the ulcerative vs the non-ulcerative patients with interstitial…
- Trial name
- NCT01479725
- Testing
- HBOT
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Kenneth Peters, MD
Painful Bladder Syndrome, Interstitial Cystitis
Study of URG101 in Painful Bladder Syndrome and Interstitial Cystitis
A double-blind, placebo-controlled study to evaluate changes in pain, urgency and urinary frequency following administration of URG101 compared to placebo.
- Conditions
- Painful Bladder Syndrome, Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT00517868
- Testing
- URG101
- Where
- 6 sites in United States
- Volunteers
- 28 people
- Sponsor
- Urigen
Cystitis, Interstitial
A Pilot Study of the Effects of Mirabegron on Symptoms in Patients With Interstitial Cystitis
Bladder pain syndrome/interstitial cystitis (BPS/IC) is a difficult disease to both diagnose and treat. It is defined as an unpleasant sensation (pain, pressure, or discomfort) perceived to be related to the urinary bladder and…
- Trial name
- MirabegronIC (NCT02787083)
- Testing
- Mirabegron
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Philadelphia Urosurgical Associates
Interstitial Cystitis and Bladder Pain Syndrome
Real-world Evidence Study on Cystistat
This study will be conducted with the aim of ensuring the continued acceptability of the benefit-risk ratio and confirming the safety and performance of the device throughout its expected lifetime.
- Trial name
- IC/BPS (NCT05544695)
- Testing
- intravesical sodium hyaluronate (Cystistat®)
- Where
- Austria
- Volunteers
- 74 people
- Sponsor
- MEDA Pharma GmbH & Co. KG
Cystitis, Interstitial
Smartphone-based Self-care Education Program for Women With Interstitial Cystitis: Educational Remote IC Aide
To implement and assess clinical efficacy of a text message and multimedia-based program that (i) remotely delivers first- and second-line American Urological Association (AUA) treatments of IC/BPS; (ii) integrates treatment of…
- Trial name
- ERICA (NCT05260112)
- Testing
- ERICA
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Pennsylvania
Interstitial Cystitis, Painful Bladder Syndrome
Pilot Study of Percutaneous Posterior Tibial Nerve Stimulation for the Treatment of IC/PBS
In 2014, the American Urological Association updated it management algorithm for Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS). As the algorithm progresses, interventions become increasingly invasive and morbid.
- Trial name
- NCT02550561
- Testing
- Posterior Tibial Nerve Stimulation
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Cystitis, Interstitial
A Study To Investigate Tanezumab In Patients With Interstitial Cystitis/ Painful Bladder Syndrome
In a previous study in patients with interstitial cystitis/ painful bladder syndrome (IC/PBS), tanezumab has shown to be efficacious in relieving the pain associated with IC/PBS, as well as some effect on reducing urinary…
- Trial name
- NCT00999518
- Testing
- Tanezumab
- Where
- 171 sites in United States, Belgium and 12 more
- Volunteers
- 205 people
- Sponsor
- Pfizer
IC - Interstitial Cystitis
Phenotyping Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) by Intravesical Contrast Enhanced - Magnetic Resonance Imaging (ICE-MRI) Bladder Permeability Assay
Each participant will be asked to participate in this research study which distinguishes different types of Interstitial Cystitis/Bladder Pain Syndrome. Research studies include only people who wish to participate.
- Trial name
- NCT05811377
- Testing
- Ferumoxytol, Gadobutrol
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Christopher J Chermansky, MD