Clinical trials: Chronic Kidney Disease, Stage 4
CKD Stage 3, CKD Stage 4
The Iron and Muscle Study
This is a multi-center randomized controlled trial that will examine the efficacy of IV iron supplementation when compared to placebo, with and without exercise training, on changes in patient exercise capacity.
- Conditions
- CKD Stage 3, CKD Stage 4, Iron-deficiency
- Trial name
- NCT04862715
- Testing
- Ferinject
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Secondary Hyperparathyroidism Due to Renal Causes, Vitamin D Insufficiency
Repeated-dose Safety, Efficacy, Pharmacokinetic and Pharmacodynamic of CTAP101, Immediate-release Calcifediol, High-dose Cholecalciferol, and Paricalcitol Plus Low-dose Cholecalciferol in Patients With Secondary Hyperparathyroidism, Chronic Kidney Disease 3-4 and Vitamin D Insufficiency
An Open-Label, Repeated-Dose Safety, Efficacy, Pharmacokinetic and Pharmacodynamic Study of Oral CTAP101 Capsules, Immediate- Release (IR) Calcifediol, High-Dose Cholecalciferol, and Paricalcitol Plus Low-Dose Cholecalciferol in…
- Conditions
- Secondary Hyperparathyroidism Due to Renal Causes, Vitamin D Insufficiency, CKD Stage 3, CKD Stage 4
- Trial name
- NCT03588884
- Testing
- Calcifediol Oral Capsule, Calcifediol Oral Product, Cholecalciferol
- Where
- 3 sites in United States
- Volunteers
- 69 people
- Sponsor
- OPKO Health, Inc.
Chronic Kidney Disease, Insulin Resistance
Study of Vitamin D3 Supplementation in Patients With Chronic Kidney Disease
The purpose of this study is to evaluate the impact of vitamin D3 supplementation on the insulin resistance in non-diabetic patients with chronic kidney disease (CKD) stages 3-4, vitamin D deficiency/insufficiency and elevated…
- Conditions
- Chronic Kidney Disease, Insulin Resistance, Vitamin D Deficiency
- Trial name
- VitaD-CKD1 (NCT00893451)
- Testing
- cholecalciferol (TillVal-D)
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Sahlgrenska University Hospital
Kidney Diseases
Efficacy and Safety of Lanthanum Carbonate in Reducing Serum Phosphorus Levels in Subjects With Stage 3 and 4 Chronic Kidney Disease
Chronic kidney disease (CKD) can result in a loss of ability to filter and excrete phosphate. The body's attempt to adjust to an increased level of phosphate in the blood can result in elevated levels of hormones and minerals…
- Trial name
- NCT00234702
- Testing
- Lanthanum carbonate
- Where
- 10 sites in United States
- Volunteers
- 84 people
- Sponsor
- Shire
Chronic Kidney Disease Stage 3, Chronic Kidney Disease
Clinical Effectiveness of MyNutriKidney®
This study is a 6-month, pragmatic, multi-center, sequentially recruited, stratified, open-label randomized controlled trial (RCT) conducted in Malaysia.
- Conditions
- Chronic Kidney Disease Stage 3, Chronic Kidney Disease, Chronic Kidney Disease Stage 5, Chronic Kidney Disease Stage 4
- Trial name
- NCT06956872
- Testing
- Counseling, Renal Diet App, Printed Nutrition Pamphlet
- Where
- Malaysia
- Volunteers
- 200 people
- Sponsor
- Universiti Putra Malaysia
Chronic Kidney Disease (stages 4 and 5)
Assessment of Protein Intake Using 2 Types of Nutritional Collection in Chronic Kidney Disease.
In France, 10% of the population suffers from chronic kidney disease (CKD). CKD is classified into five stages, described from the least severe (stage 1) to the most severe (stage 5).
- Trial name
- APRONUT_MRC (NCT06224153)
- Testing
- 3-day dietary record, Food Frequency Questionnaire (FFQ)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Chronic Kidney Disease, Stage 5, Chronic Kidney Disease, Stage 4
A Cohort Study on the Integrated Management of Chronic Kidney Disease
The study will leverage the established multi-stage cohort resources at Huashan Hospital, covering the entire spectrum from early-stage CKD to dialysis, including a comorbidity real-world database, a prospective CKD patient…
- Conditions
- Chronic Kidney Disease, Stage 5, Chronic Kidney Disease, Stage 4, Chronic Kidney Disease, Stage 3
- Trial name
- NCT07712341
- Testing
- Retrospective data collection, Prospective data collection, External validation
- Where
- China
- Volunteers
- 4,029 people
- Sponsor
- Huashan Hospital
Osteopenia, Bone Metabolism Disorders
Effects of Aerobic Versus Resistance Training on Bone Metabolism in Stage 3-4 Chronic Kidney Disease
This randomized controlled trial investigates the comparative effects of aerobic versus resistance training on bone mineral density (BMD) and bone metabolism markers in patients with stage 3 or 4 chronic kidney disease (CKD).
- Conditions
- Osteopenia, Bone Metabolism Disorders, Chronic Kidney Disease (Stage 3-4), Mineral and Bone Disorder (CKD-MBD)
- Trial name
- CKD-BONE-EX (NCT07133256)
- Testing
- Resistance Exercise, Aerobic Training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sinai University
Percutaneous Nephrolithotomy
Percutaneous Nephrolithotomy in Patients With Stage 2-4 Chronic Kidney Disease
The study aims to evaluate the effect of percutaneous nephrolithotomy (PCNL) on estimated glomerular filtration rate (eGFR) in patients with stage 2-4 chronic kidney disease
- Trial name
- NCT04943081
- Testing
- Percutaneous nephrolithotomy
- Volunteers
- 50 people
- Sponsor
- Assiut University
CKD Stage 4, CKD Stage 5
The Effects of Application Intervention on the Physiological Indicators and Low Protein Diet Cognition Among the Patients With Chronic Kidney Disease
The effects of Application intervention on the physiological indicators and low protein diet cognition among the patients with chronic kidney disease
- Trial name
- NCT06083545
- Testing
- App
- Where
- Taiwan
- Volunteers
- 184 people
- Sponsor
- yi ting Hsu
Chronic Kidney Disease (Stage 3-4), Chronic Kidney Disease Mineral and Bone Disorder
Phosphate Assessment in Chronic Kidney Disease Patients Study
The proposed pilot feeding study aims to explore novel pathways in phosphate metabolism and identify new biomarkers, as well as to develop a compound index for assessing phosphate overload with high validity and reliability.
- Trial name
- PACK (NCT07368946)
- Testing
- Dietary Phosphorus Intake
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Chronic Kidney Diseases
A Study to Explore the Renal Safety of Visipaque Injection 320 mgI/mL in Patients With Chronic Kidney Disease
This parallel-group, randomized, placebo-controlled study will examine the incidence and severity of acute kidney injury (AKI) in patients with chronic kidney disease (CKD) stage III/IV following an i.v.
- Trial name
- NCT03119662
- Testing
- Visipaque
- Where
- 29 sites in United States, Belgium and 4 more
- Volunteers
- 4 people
- Sponsor
- GE Healthcare
Chronic Kidney Disease Stage 4, Chronic Kidney Disease Stage 3
Primary Cardiovascular Risk Prevention With Aspirin in Chronic Kidney Disease Patients
The objective of the study is to examine whether the use of low-dose aspirin (75-100 mg / day) reduces the risk of cardiovascular disease in patients with chronic kidney disease (stage 3 or 4).
- Trial name
- NCT01709994
- Testing
- Aspirin
- Where
- Spain
- Volunteers
- 97 people
- Sponsor
- Fundación de Ayuda a la Investigación sobre la Hipertensión, Riesgo Cardiovascular y Enfermedades Renales
Hyperkalemia, Chronic Kidney Disease (Stages 4 and 5)
Safety of a Healthy Plant-based Diet With Higher Potassium Content, Compared to a Healthy Plant-based Diet With Limited Potassium Content in Patients With Chronic Kidney Disease: A Pilot Study
For many years, people with moderate to advanced chronic kidney disease (CKD) have been advised to limit their intake of potassium, a mineral found in many foods such as fruit, vegetables, legumes, whole grains, and nuts.
- Trial name
- SAFE-K (NCT07494266)
- Testing
- Healthy plant-based diet (healthy-PBD), Potassium-restricted plant-based diet
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Chronic Kidney Disease
Efficacy of Pentoxifylline on Chronic Kidney Disease
To study whether pentoxifylline has additive renoprotective effect in patients taking ARB
- Trial name
- NCT00155246
- Testing
- pentoxifylline (drug)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Chronic Kidney Disease (Stage 3-4)
Effects of Maqui Supplementation on Gut Microbiota, Inflammation, and Oxidative Stress in Patients With Chronic Kidney Disease
Chronic kidney disease (CKD) is a highly prevalent condition in Chile and worldwide and is associated with a substantial burden of morbidity, particularly cardiovascular morbidity.
- Trial name
- maquibiota (NCT07776925)
- Testing
- maqui supplementation, PLA
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Universidad Mayor
Breast Cancer, Chronic Myeloproliferative Disorders
Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer
RATIONALE: Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. Combining chemotherapy and peripheral stem cell transplantation with biological therapy may kill more cancer…
- Conditions
- Breast Cancer, Chronic Myeloproliferative Disorders, Gestational Trophoblastic Tumor, Kidney Cancer
- Trial name
- NCT00003408
- Testing
- aldesleukin, recombinant interferon alfa, sargramostim
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Cancer Treatment Centers of America
Chronic Kidney Disease (Stage 3-4), Chronic Kidney Disease (Stages 4 and 5)
Prospective Analysis of Self Medication With Phytotherapy in Nephropatic Patients.
We propose the following hypotheses: The use of herbal medicine is common among patients with chronic kidney disease in Réunion island. This use could influence the progression of kidney disease in these patients.
- Trial name
- PASSION (NCT07444515)
- Testing
- series of questions which can change patient care
- Where
- 4 sites in France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Chronic Kidney Disease Stage 4
The Agenda-Setting for Kidney Disease Open Pilot Trial
The goal of this open pilot is to practice using an intervention and surveys before a larger pilot stepped wedge clinical trial.
- Trial name
- ASK (NCT07221604)
- Testing
- Chronic Kidney Disease Structured Agenda-Setting Tool
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Dartmouth-Hitchcock Medical Center