Clinical trials: Chronic Kidney Disease 5D
Chronic Kidney Disease 5D
Bio-ADM as a Biomarker of Refilling in Chronic Hemodialysis Patient
Aim of this study is to evaluate in a population of chronic kidney disease patients on dialysis (Stage 5D) the predictive value of bio-adrenomedullin (bio-ADM) level on vascular refilling rate.
- Trial name
- REFILBIOADM (NCT05339009)
- Testing
- BioADM determination in plasma
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Chronic Kidney Diseases
Study Evaluating the Effect of Isonatremic Dialysis Treatment in Chronic Kidney Disease Patients on Dialysis
Aim of this study is to evaluate, in a population of chronic kidney disease patients on dialysis (Stage 5D), the effect of treatment with isonatremic dialysis (vs conventional dialysis), during an observational period of 2 months…
- Trial name
- DISON-IRC (NCT04809493)
- Testing
- Conventional dialysis treatment, Isonatremic dialysis treatment
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Montpellier
Kidney Transplantation, CKD (Chronic Kidney Disease) Stage 5D
Tubeless Spontaneous Ventilation Anesthesia in Kidney Transplantation
The aim of this clinical trial is to compare the intraoperative use of neuromuscular blocking agents and other anesthetic drugs between tubeless spontaneous ventilation anesthesia (TSVA) and conventional endotracheal intubation…
- Trial name
- NCT07377123
- Testing
- Tubeless Spontaneous Ventilation Anesthesia, Endotracheal Tube Anesthesia
- Volunteers
- 60 people
- Sponsor
- Jianxing He
Chronic Kidney Disease 5D, Secondary Hyperparathyroidism
A Observational Study to Evaluate the Efficacy and Safety of Pacitol Inj.
The purpose of this study is to evaluate the efficacy and safety of pacitol Inj.(paricalcitol) for secondary hyperparathyroidism with stage 5D chronic kidney disease (CKD 5D) receiving hemodialysis
- Trial name
- NCT06126016
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Cardiac Surgery Associated - Acute Kidney Injury, CKD (Chronic Kidney Disease) Stage 5D
Incidence and Prognostic of Cardiac Surgery-Associated Acute Kidney Injury: A Spanish Multicenter Study (SCARS-AKI)
To predict the renal damage caused by cardiac surgery in patients to try to mitigate it as soon as possible
- Conditions
- Cardiac Surgery Associated - Acute Kidney Injury, CKD (Chronic Kidney Disease) Stage 5D, Acute Kidney Injury, Acute Kidney Disease
- Trial name
- SCARS-AKI (NCT07370831)
- Testing
- CARDIAC SURGERY
- Where
- Spain
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Universidad de Oviedo
Dialysis; Complications, Chronic Kidney Disease 5D
Pegmolesatide Treatment for Anemia in Patients Undergoing Long-term Dialysis
This study is a prospective, multicenter, parallel-controlled, open-label clinical trial, planned to be conducted across multiple research centers in various provinces and cities in China.
- Conditions
- Dialysis; Complications, Chronic Kidney Disease 5D, Renal Anemia of Chronic Kidney Disease, Renal Anaemia
- Trial name
- PANGU-stepup (NCT07045155)
- Testing
- The rHuEPO Monotherapy Group (Control Group), The Pegmolesatide and Roxadustat Combination Therapy Group (Exploratory Group), The Pegmolesatide Monotherapy Group (Experimental group)
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Chinese PLA General Hospital
Chronic Kidney Disease 5D
Cross-control Study on the Effect of Peritoneal Rest on Peritoneal Transport Function in Peritoneal Dialysis Patients
The investigators will carry out a prospective cross-over, pre-and post-controlled clinical study : 36 patients with continuous ambulatory peritoneal dialysis with high/high average transport will be recruited and treated with…
- Trial name
- CSEPR (NCT05805813)
- Testing
- peritoneal rest
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Peking University People's Hospital
CKD (Chronic Kidney Disease) Stage 5D
NGAL and Hepcidin Levels in Hemodialysis Patients in Assiut University Hospital
To assess the pattern of NGAL and Hepicidin in relation to anemia in End Stage Renal Disease Patients on regular hemodialysis in Assiut University Hospital and study the relation between both NGAL and Hepicidin.
- Trial name
- NCT04083664
- Testing
- NGAL and Hepcidin
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Chronic-kidney Disease Stage 5D on Stable Hemodialysis
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of VS 105
The purpose of the study is to evaluate the safety, tolerability, and PK following single and multiple ascending dose administration of VS-105 in healthy subjects and patients with chronic kidney disease stage 5D (CKD-5D) on…
- Trial name
- NCT03043482
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Vidasym, Inc.
ESRD, CKD (Chronic Kidney Disease) Stage 5D
Effect of Canagliflozin on Ultrafiltration & Fibrosis in Patients on Peritoneal Dialysis
This is a phase II, proof-of-concept, placebo-controlled, double-blind, cross-over randomized clinical trial, assessing the effect of canagliflozin on peritoneal membrane function in patients on PD.
- Trial name
- CAN-PD (NCT06913647)
- Testing
- Canagliflozin 300 MG
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
End Stage Renal Disease (ESRD), Arteriovenous Fistula Patency
Anesthetic Effect of Ropivacaine on Local Infiltration Anesthesia in Arteriovenous Fistula Surgery
This study compares two local anesthetics, ropivacaine and lidocaine, for patients undergoing arteriovenous fistula surgery. Arteriovenous fistula is the preferred vascular access for end-stage kidney disease patients needing…
- Conditions
- End Stage Renal Disease (ESRD), Arteriovenous Fistula Patency, Chronic Kidney Disease 5D
- Trial name
- NCT07259772
- Testing
- Ropivacaine, Lidocaine
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First People's Hospital of Lianyungang
Covid19, Chronic Kidney Disease 5D
Immune Response in Dialysis Patients Vaccinated Against COVID-19
This is a prospective cohort study aimed to evaluate short- and mid-term immune response after SARS-CoV-2 vaccination using Gam-COVID-Vac (Sputnik V) vaccine in dialysis patients compared to the control group (medical staff).
- Trial name
- Sputnik-HD (NCT04805632)
- Where
- Russia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Saint Petersburg State University, Russia
CKD (Chronic Kidney Disease) Stage 5D, Pneumonia
Duration of Protection From Pneumonia After Pneumococcal Vaccination in Hemodialysis Patients
The investigators compare two strata of vaccinated patients: those recently vaccinated and those vaccinated more than two years ago. The primary objective is to compare pneumonia rates between the groups.
- Trial name
- DOPPIO (NCT03350425)
- Where
- 12 sites in Germany
- Volunteers
- 792 people
- Sponsor
- University of Cologne
Chronic Kidney Disease 5D, Secondary Hyperparathyroidism Due to Renal Causes
A Study on Prevention Strategies for CKD-SHPT and Related Complications Based on General Vitamin D Supplementation
1. Study content: This is a multicentre, double-blind, randomised controlled study to determine the optimal dose and duration of treatment for the correction of vitamin D insufficiency or deficiency in patients with CKD5d; to…
- Conditions
- Chronic Kidney Disease 5D, Secondary Hyperparathyroidism Due to Renal Causes, Vitamin D Deficiency
- Trial name
- NCT05549154
- Testing
- High-dose vitamin D2 softgels, low-dose vitamin D2 softgels
- Where
- China
- Volunteers
- 372 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Chronic Kidney Diseases
Ionized Magnesium Balance During Hemodialysis Session
Aim of this study is to evaluate in a population of chronic kidney disease patients on dialysis (Stage 5D) the balance of total and ionized magnesium according to different types of dialysate used in clinical practice (acetate +…
- Trial name
- MAGNESIR (NCT05337436)
- Testing
- Lymphatic drainage, Total and ionized magnesium, Total and ionized calcium
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Chronic-kidney Disease Stage 5D on Stable Hemodialysis
Study of Safety and Tolerability of BPS804 in Patients With Late-stage Chronic Kidney Disease
The purpose of the study is to evaluate the safety, tolerability, and PK following a single administration of BPS804 in patients with chronic kidney disease stage 5D (CKD-5D) on hemodialysis.
- Trial name
- NCT01806610
- Testing
- BPS804
- Sponsor
- Ultragenyx Pharmaceutical Inc
CKD (Chronic Kidney Disease) Stage 5D, Peritoneal Dialysis (PD)
The Effect of Exercise on Blood Pressure Variability on Peritoneal Dialysis Patients
In China, the chronic kidney disease (CKD) incidence rate is as high as 10.8%. Renal replacement therapy plays an critical role in the later stage of CKD and becomes mandatory, as end-stage renal disease (ESRD) is unavoidable in…
- Trial name
- NCT07098923
- Testing
- combination of aerobic and resistance exercise
- Where
- China
- Volunteers
- 55 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Osteoporosis, Chronic Kidney Disease 5D
Study Evaluating Denosumab on Vascular and Bone Metabolism in Osteoporotic Chronic Kidney Disease (HDENOBS)
Aim of this study is to evaluate in a population of osteoporotic chronic kidney disease patients the effect of denosumab: on coronary artery calcification scores evolution after 24 months of followup on abdominal aorta…
- Trial name
- HDENOBS (NCT05234047)
- Testing
- MDCT (multidetector computed tomography), Dual-energy X-ray absorptiometry
- Volunteers
- 21 people
- Sponsor
- University Hospital, Montpellier
CKD (Chronic Kidney Disease) Stage 5D
Impact of CKD on Children and Their Families
Based on the available literatures, previous studies have investigated the impact of CKD and dialysis on patient's health among adult and elderly population.
- Trial name
- NCT04538443
- Testing
- functional capacity, muscle strength, Quality of life of children
- Volunteers
- 100 people
- Sponsor
- Cairo University
Chronic Kidney Disease 5D, Heart Failure
Cardio-fistular Recirculation in Patients With Chronic Heart Failure and Preserved Left Ventricle Ejection Fraction
This is a single-arm cohort study aimed to evaluate change of arteriovenous fistula volume blood flow / cardiac output ratio in patients with chronic heart failure (NYHA I-II classes) and with preserved ejection fraction as a…
- Conditions
- Chronic Kidney Disease 5D, Heart Failure, Heart Failure NYHA Class I, Heart Failure NYHA Class II
- Trial name
- NCT06394986
- Testing
- Hemodialysis session
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- Moscow Regional Research and Clinical Institute (MONIKI)