Clinical trials: Chronic Kidney Disease 5D, active
Type 2 Diabetes, Chronic Kidney Disease 5D
A Multi-centre Trial to Assess the Efficacy and Safety of the Omnipod 5 System in People With Type 2 Diabetes Undergoing Haemodialysis
Diabetes is the leading cause of kidney failure in the UK. Many people with diabetes and advanced kidney failure inject themselves with insulin and do finger-prick blood glucose tests.
- Trial name
- AID-HD (NCT07422532)
- Testing
- Omnipod 5, Insulin injections
- Where
- 4 sites in United Kingdom
- Volunteers
- 84 people
- Sponsor
- Imperial College London
CKD (Chronic Kidney Disease) Stage 5D
ASPIrin in Reducing Events in Dialysis ( ASPIRED )
People with kidney failure requiring dialysis have a much higher risk of developing cardiovascular (CV) disease compared with the general population.
- Trial name
- NCT04381143
- Testing
- Aspirin 100 mg Oral Tablet
- Where
- 127 sites in China
- Volunteers
- 9,082 people
- Sponsor
- Guangdong Provincial People's Hospital
Anemia, Chronic Kidney Disease
Study of the Efficacy and Safety of BCD-131 and Mircera® in the Treatment of Anemia in Patients With Chronic Kidney Disease on Dialysis
BCD-131 is pegylated darbepoetin beta. This clinical study BCD-131-3 is a randomized, open-label, phase III study of the efficacy and safety of BCD-131 and Mircera used for the treatment of anemia in end-stage chronic kidney…
- Conditions
- Anemia, Chronic Kidney Disease, Chronic Kidney Disease Patients on Hemodialysis, Chronic Kidney Disease 5D
- Trial name
- NCT07119372
- Testing
- BCD-131 (pegdarbepoetin beta), Mircera (methoxypolyethylene glycol-epoetin beta)
- Where
- 14 sites in Russia
- Volunteers
- 228 people
- Sponsor
- Biocad
Chronic Kidney Disease 5D
Intradialytic Exercise Combined With Creatine Monohydrate in Patients With Chronic Kidney Disease Undergoing Hemodialysis.
This study aims to evaluate the effects of creatine monohydrate supplementation and an intradialytic exercise program on body composition, biochemical parameters, and functional capacity in patients with chronic kidney disease…
- Trial name
- NCT07666815
- Testing
- Group A with creatine monohydrate, Group C Intradialytic Exercise Program, Comparison group D Hemodialysis
- Where
- Mexico
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Pedro Julian Flores Moreno
Chronic Kidney Disease 5D, Chronic Kidney Disease Stage 5
Kidney Transplant Improvement Through New Exercise Training to Increase Capacity
The goal of this clinical trial is to learn if a home-based exercise program can be safely and feasibly used to improve physical activity and physical function in adults waiting for a kidney transplant.
- Conditions
- Chronic Kidney Disease 5D, Chronic Kidney Disease Stage 5, Kidney Failure, Kidney Failure,Chronic
- Trial name
- KINETIC (NCT07446296)
- Testing
- Exercise Rehabilitation Program with Physical Activity Tracker, Active control
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pennsylvania
Chronic Kidney Disease 5D, Uremia; Chronic
ICHARUS: Italian Cooperative HemoAdsorption Study for Relief of Uremic Symptoms
Background: Many patients receiving maintenance hemodialysis continue to experience persistent uremic symptoms, such as pruritus, fatigue, sleep disorders, reduced physical performance, and impaired quality of life, despite…
- Trial name
- ICHARUS (NCT07522008)
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliera Brotzu
ESRD, CKD (Chronic Kidney Disease) Stage 5D
Effect of Canagliflozin on Ultrafiltration & Fibrosis in Patients on Peritoneal Dialysis
This is a phase II, proof-of-concept, placebo-controlled, double-blind, cross-over randomized clinical trial, assessing the effect of canagliflozin on peritoneal membrane function in patients on PD.
- Trial name
- CAN-PD (NCT06913647)
- Testing
- Canagliflozin 300 MG
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Chronic Kidney Disease (Stages 4 and 5), Chronic Kidney Disease 5D
The Practicality and Utility of Measured vs Estimated GFR in adCKD
The goal of this observational study is to assess if new ways of measuring kidney function can better predict when individuals will become symptomatic due to kidney failure, and whether residual kidney function can be accurately…
- Trial name
- NCT07450534
- Testing
- Iohexol Inj 300 MG/ML Diagnostic aid/agent used to measure glomerular filtration rate (GFR)
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Manchester University NHS Foundation Trust
Kidney Transplantation, CKD (Chronic Kidney Disease) Stage 5D
Tubeless Spontaneous Ventilation Anesthesia in Kidney Transplantation
The aim of this clinical trial is to compare the intraoperative use of neuromuscular blocking agents and other anesthetic drugs between tubeless spontaneous ventilation anesthesia (TSVA) and conventional endotracheal intubation…
- Trial name
- NCT07377123
- Testing
- Tubeless Spontaneous Ventilation Anesthesia, Endotracheal Tube Anesthesia
- Volunteers
- 60 people
- Sponsor
- Jianxing He
CKD (Chronic Kidney Disease) Stage 5D, Uremia; Chronic
Studies on Adsorption International Learning Initiative Global
Use of sorption technologies in patients undergoing maintenance hemodialysis with inflammatory syndrome and clinical manifestations of uremia
- Conditions
- CKD (Chronic Kidney Disease) Stage 5D, Uremia; Chronic, Uremic; Toxemia, Inflammation Chronic
- Trial name
- SAILING (NCT07123909)
- Testing
- Patients will undergo a combined hemodialysis and hemosorption procedure. The study cartridge for hemosorption by Jafron HA130 contains the original adsorbing material.
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Botkin Hospital
End Stage Renal Disease (ESRD), Arteriovenous Fistula Patency
Anesthetic Effect of Ropivacaine on Local Infiltration Anesthesia in Arteriovenous Fistula Surgery
This study compares two local anesthetics, ropivacaine and lidocaine, for patients undergoing arteriovenous fistula surgery. Arteriovenous fistula is the preferred vascular access for end-stage kidney disease patients needing…
- Conditions
- End Stage Renal Disease (ESRD), Arteriovenous Fistula Patency, Chronic Kidney Disease 5D
- Trial name
- NCT07259772
- Testing
- Ropivacaine, Lidocaine
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First People's Hospital of Lianyungang
Dialysis; Complications, Chronic Kidney Disease 5D
Pegmolesatide Treatment for Anemia in Patients Undergoing Long-term Dialysis
This study is a prospective, multicenter, parallel-controlled, open-label clinical trial, planned to be conducted across multiple research centers in various provinces and cities in China.
- Conditions
- Dialysis; Complications, Chronic Kidney Disease 5D, Renal Anemia of Chronic Kidney Disease, Renal Anaemia
- Trial name
- PANGU-stepup (NCT07045155)
- Testing
- The rHuEPO Monotherapy Group (Control Group), The Pegmolesatide and Roxadustat Combination Therapy Group (Exploratory Group), The Pegmolesatide Monotherapy Group (Experimental group)
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Chinese PLA General Hospital
End Stage Renal Disease (ESRD), CKD 5D, Hemodialysis
Activated Charcoal Use in Chronic Kidney Disease Patients
Hyperphosphatemia management is initially based on restricting dietary phosphorus intake. Hyperphosphatemia is almost always seen in patients on dialysis and may contribute to progressive vascular calcification.
- Conditions
- End Stage Renal Disease (ESRD), CKD 5D, Hemodialysis, CKD-MBD - Chronic Kidney Disease Mineral and Bone Disorder
- Trial name
- NCT06906874
- Testing
- Activated Charcoal, Phosphate Binders
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
CKD (Chronic Kidney Disease) Stage 5D, Hemodialysis
Effect of Kidney Replacement Therapy with Polymethylmethacrylate Membranes on Pruritus-related Quality of Life in Patients Receiving Maintenance Haemodialysis
This randomized controlled trial aims to evaluate the effect of polymethylmethacrylate dialysis membranes use on the intensity of pruritus in patients with CKD stage 5D receiving maintenance hemodialysis.
- Conditions
- CKD (Chronic Kidney Disease) Stage 5D, Hemodialysis, Pruritis
- Trial name
- NCT06671535
- Testing
- Polymethylmethacrylate membrane, polysulfone membranes
- Where
- Russia
- Volunteers
- 62 people
- Sponsor
- Saint Petersburg State University, Russia
CKD (Chronic Kidney Disease) Stage 5D
Impact of Propionic Acid on Regulatory T Cell Function in Children With CKD
Pro-Kids is a multi-center, double-blind, randomized and placebo-controlled intervention study in children with chronic kidney disease.
- Trial name
- Pro-Kids (NCT05858437)
- Testing
- Sodium propionate
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Charite University, Berlin, Germany
Chronic Kidney Disease 5D, Secondary Hyperparathyroidism
A Observational Study to Evaluate the Efficacy and Safety of Pacitol Inj.
The purpose of this study is to evaluate the efficacy and safety of pacitol Inj.(paricalcitol) for secondary hyperparathyroidism with stage 5D chronic kidney disease (CKD 5D) receiving hemodialysis
- Trial name
- NCT06126016
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Chronic Kidney Disease 5D
Feasibility of a Randomized Cluster Trial for Blood Pressure Targets in In-centre Hemodialysis Units
High blood pressure in people receiving hemodialysis is known to contribute to heart disease and heart-related death from strokes, heart failure, left ventricular hypertrophy (which is a thickening of the heart wall that makes it…
- Trial name
- NCT06695611
- Testing
- Increase systolic blood pressure, Decrease systolic blood pressure
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Manitoba
Chronic Kidney Disease 5D
Effect of Inulin on Gut Microbiota and Gut Barrier in Chronic Kidney Disease
An adequate fiber intake is crucial for a well-balanced diet and reduces the risk of chronic diseases. However, nutritional recommendations for chronic kidney disease patients lead to an insufficient fiber intake with possible…
- Trial name
- RESTORE (NCT05071131)
- Testing
- Inulin
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Charite University, Berlin, Germany
AKI, CKD
Genetics in the Progression of Nephropathies
This study evaluates the role of genetic in the development and progression of different nephropaties with particular attention to: AKI CKD Hypertension ADPKD CKD-MBD Patients with decompensated heart failure undergoing either…
- Conditions
- AKI, CKD, Ckd-Mbd, CKD (Chronic Kidney Disease) Stage 5D
- Trial name
- NCT06416761
- Testing
- genetic polymorphisms
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- Ospedale San Raffaele