Clinical trials: Chronic Kidney Disease Patients
Chronic Kidney Diseases
Kidney AI-enabled Care Transformation
In the Kidney ACTion study, CKD (Chronic Kidney Disease) patients at increased risk of progression to ESRD (End Stage Renal Disease) will be randomly assigned to either standard of care in a specialist nephrology outpatient…
- Trial name
- NCT05056909
- Testing
- Kidney ACTion, Standard of care
- Where
- 2 sites in Italy, United Kingdom
- Sponsor
- Medical University of Graz
Vitamin D Deficiency, End-stage Renal Disease
Impact of Vitamin D Repletion in Hemodialysis Patients
Dialysis patients often suffer from defects in their immune system (that part of the body which fights infection). Evidence suggests that Vitamin D deficiency may have a negative effect on immunity, and many dialysis patients are…
- Trial name
- NCT01175798
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Mehrotra, Anita, M.D.
Chronic Kidney Diseases
Survey on Anemia Therapy in Participants With Chronic Kidney Disease (CKD) Not on Dialysis
This study is a prospective, non-interventional, cross-sectional multicenter survey. The aim is to better understand the current therapy pattern for anemia in CKD treated with erythropoiesis-stimulating agents (ESAs) and not…
- Trial name
- NCT02238067
- Testing
- ESA, Satisfaction Survey Questionnaire
- Where
- 7 sites in Israel
- Volunteers
- 196 people
- Sponsor
- Hoffmann-La Roche
Chronic Renal Failure
Efficacy of an Intradialysis Combined Training Program on Disability Level and Physical Performance.
The patient subjected to hemodialysis has a low physical capacity due to being advanced in years and the complexity of the process, which is encouraged by family members and caregivers who lead them to a total dependence.
- Trial name
- PTH-CKD0113 (NCT02883309)
- Testing
- intradialytic physical training program
- Sponsor
- Universidad Austral de Chile
End Stage Renal Disease, Inflammation
Influence of the Vitamine E Coated Dialyzer on Inflammation and Anemia
Evaluation of the effect of a vitamin E coated high flux polysulfone dialyzer on the inflammatory state of patients' end stage renal disease and its clinical benefits in terms of anemia Objectives : To assess the benefits of a…
- Trial name
- EVIA (NCT03218865)
- Testing
- VIE high flux dialyzer, Leoceed H high flux dialyzer
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Hemotech
Secondary Hyperparathyroidism, End Stage Renal Disease
Efficacy and Safety of High Intensity Focused Ultrasound (HIFU) Device to Treat Secondary Hyperparathyroidism
Secondary hyperparathyroidism (sHPT) is common in patients with chronic kidney disease (CKD), including those who are undergoing long-term haemodialysis treatment.
- Conditions
- Secondary Hyperparathyroidism, End Stage Renal Disease, Parathyroid Hyperplasia
- Trial name
- NCT01421407
- Testing
- Ultrasonic ablation device
- Where
- 3 sites in Italy, Spain
- Sponsor
- Theraclion
Chronic Kidney Disease, Renal Insufficiency
Long-term Study in Chronic Kidney Disease Patients With Hyperphosphatemia Not on Dialysis
This is a multi-center, open-labeled, non-comparative study to examine the safety and efficacy of ASP1585 for long-term dosing in chronic kidney disease patients with hyperphosphatemia not on dialysis.
- Conditions
- Chronic Kidney Disease, Renal Insufficiency, Hyperphosphatemia
- Trial name
- NCT01742611
- Testing
- ASP1585
- Where
- 5 sites in Japan
- Volunteers
- 105 people
- Sponsor
- Astellas Pharma Inc
Chronic Kidney Disease Stage 5, Chronic Kidney Disease Stage 4B
Prognostic Value of a Multidimensional Assessment for Survival in Elderly Patients With CKD 4B/5
The aim of this study is to determine a multidimensional signature (integrating frailty and patient-reported outcomes measures (PROMs) at entry into stage 4B/5 CKD) to improve prediction of renal death (dialysis, transplantation…
- Trial name
- PROFILER (NCT06825234)
- Where
- 2 sites in France
- Volunteers
- 390 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
End-stage Renal Disease, Hemodialysis
Does Moderate Physical Activity in Hemodialysis Patients Reduce Inflammation?
The purpose of this study is to observe a potential benefit of moderate physical activity by using bed mounted cycles during hemodialysis treatment sessions on inflammatory markers in the blood of patients with end-stage renal…
- Trial name
- NCT00893165
- Testing
- moderate physical activity
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Predictive Modeling
Refining Risk Prediction Models for Older Adults Using Electronic Health Records
This study aims to improve how lab results are communicated to older adults by refining a predictive model that uses electronic health record (EHR) data.
- Trial name
- NCT06995365
- Testing
- Risk Prediction Model
- Where
- United States
- Volunteers
- 18,000 people
- Sponsor
- University of California, Los Angeles
Hyperphosphatemia
A Phase 2 Study to Evaluate the Safety and Efficacy of VS-505(AP301) to Treat Hyperphosphatemia in Hemodialysis Patients
A multi-center, open-label, parallel-design, active-controlled phase 2 study to evaluate the tolerability, safety and efficacy of various dosages of VS-505 compared with Sevelamer Carbonate when given orally with meal for 6 weeks…
- Trial name
- NCT04551300
- Testing
- VS-505, Sevelamer Carbonate
- Where
- 23 sites in China
- Volunteers
- 158 people
- Sponsor
- Shanghai Alebund Pharmaceuticals Limited
Peritonitis
Effect of Icodextrin on the Treatment Outcome of Peritoneal Dialysis Patients During Acute Peritonitis
The objective of the present study is to evaluate the a prior hypothesis that treatment with icodextrin during acute peritonitis would improve the treatment outcomes of peritonitis complicating peritoneal dialysis.
- Trial name
- NCT01044446
- Testing
- Icodextrin, glucose-based peritoneal dialysate
- Where
- Hong Kong
- Volunteers
- 56 people
- Sponsor
- Chinese University of Hong Kong
Acute Kidney Injury
Improving Patient Assessment After Acute Kidney Injury (AKI)
The goal of this clinical trial is to improve patient care after acute kidney injury (AKI). It has three related parts. The main questions it aims to answer are: 1.
- Trial name
- IMPACT-AKI (NCT07569588)
- Testing
- Iohexol renal clearance measurement, Cystatin C, Creatinine
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Nottingham
Hyperphosphataemia, Phosphorus
Phosphate Diet Strategies to Lower Blood Phosphate in Dialysis Patients
Raised phosphate levels in the blood (hyperphosphatemia) are frequently observed in hemodialysis patients with chronic kidney failure.
- Conditions
- Hyperphosphataemia, Phosphorus, Diet Therapy, Chronic Kidney Disease 5D
- Trial name
- NCT07180069
- Testing
- diet education
- Where
- Iraq
- Volunteers
- 200 people
- Sponsor
- Kufa University
Hemodialysis, End Stage Chronic Renal Failure
Mindfulness for Saudi Hemodialysis Patients
This study aims to evaluate whether an MBI improves sleep quality, emotional symptoms (depression, anxiety, stress), emotion regulation, and trait mindfulness among adults with ESRD on HD.
- Trial name
- MSHP (NCT07816354)
- Testing
- Mindfulness-Based Intervention
- Where
- Saudi Arabia
- Volunteers
- 38 people
- Sponsor
- Jordan University of Science and Technology
End Stage Renal Disease
Inflammation, Proteolysis and IL-1 Beta Receptor Inhibition in Chronic Hemodialysis Patients
Chronic hemodialysis (CHD) patients display multiple metabolic abnormalities related to advanced uremia. Despite vigorous attempts to prevent these abnormalities and their consequences, most CHD patients suffer from a unique form…
- Trial name
- NCT00420290
- Testing
- kineret
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Vanderbilt University
Kidney Transplant Rejection, End Stage Renal Disease
Long-Term Follow-Up of TX200-TR101 (STEADFAST Long Term)
This long-term follow-up study is being conducted to collect long-term (up to 15 years post-infusion) safety and tolerability data from subjects enrolled in studies evaluating TX200-TR101.
- Trial name
- NCT05987527
- Testing
- Blood sample
- Where
- 5 sites in Belgium, Netherlands and 1 more
- Volunteers
- 11 people
- Sponsor
- Sangamo Therapeutics
ESRD
Examination of Potassium Levels in Saliva in ESRD Patients
Dialysis patients typically undergo 3 treatments a week every other day with an almost 3 day gap during the weekend. After this gap and before the first dialysis of the week the serum Potassium level is expected to be maximal.
- Trial name
- NCT02596386
- Testing
- sialometry, blood test
- Volunteers
- 50 people
- Sponsor
- Hadassah Medical Organization
Chronic Kidney Disease, Albuminuria
Sodium Lowering and Urinary Protein Reduction Trial
The proposed randomized controlled trial will test the effect of dietary sodium reduction on albuminuria in patients with proteinuric chronic kidney disease.
- Trial name
- SUPER (NCT02945969)
- Testing
- Low Sodium Diet
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- Tulane University School of Public Health and Tropical Medicine
Anemia of Chronic Kidney Disease, CKD
Real-World Study of Enarodustat for Anemia in Non-Dialysis CKD Patients
This is a single-center, prospective real-world observational study aiming to evaluate the efficacy and safety of oral enarodustat in adult non-dialysis chronic kidney disease (ND-CKD) patients with renal anemia.
- Conditions
- Anemia of Chronic Kidney Disease, CKD, Non-dialysis Chronic Kidney Disease
- Trial name
- NCT07741279
- Testing
- Enarodustat
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Huashan Hospital
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