Clinical trials: Chronic Kidney Disease Requiring Hemodialysis
Hemodialysis, Coronary Arterial Disease (CAD)
Predictive Tools for the Presence of Significant Coronary Artery Disease Requiring Intervention in Chronic Hemodialysis Patients
Medical record data of all HD patients undergoing coronary angiography (CAG) at King Chulalongkorn Memorial Hospital between January 2017 and March 2021 were retrospectively reviewed as a discovery cohort to identify factors…
- Conditions
- Hemodialysis, Coronary Arterial Disease (CAD), ESRD (End Stage Renal Disease)
- Trial name
- CAD in HD (NCT06661941)
- Where
- Thailand
- Volunteers
- 149 people
- Sponsor
- Chulalongkorn University
Chronic Kidney Disease Requiring Chronic Dialysis
Reduction of Oxalate and Inflammation by Hemodiafiltration vs. Hemodialysis
The health care burden of CKD is substantial and growing with 10-15% of the population affected in both developed and developing countries.
- Trial name
- NCT02684656
- Testing
- Hemodialysis, Hemodiafiltration
- Where
- Germany
- Volunteers
- 14 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Chronic Kidney Disease (CKD) Stage 5, Kidney Dysfunction Requiring Dialysis (KDRD)
Incremental Hemodialysis for Veterans in the First Year of Dialysis (IncHVets)
In this pragmatic clinical trial, which will dovetail with Veterans' routine outpatient dialysis clinic visits in six VA medical centers, the investigators will study 252 Veterans with kidney disease who need to start dialysis…
- Conditions
- Chronic Kidney Disease (CKD) Stage 5, Kidney Dysfunction Requiring Dialysis (KDRD), Dialysis Dependency
- Trial name
- INCHVETS (NCT05465044)
- Testing
- Twice-weekly hemodialysis with incremental crossover to thrice-weekly schedule, Thrice-Weekly Hemodialysis
- Where
- 8 sites in United States
- Volunteers
- 252 people
- Sponsor
- VA Office of Research and Development
Chronic Kidney Disease Requiring Chronic Dialysis, Chronic Kidney Diseases
Cardiopulmonary Exercise Testing Parameters' Variability in Hemodialysis Patients.
Chronic kidney disease (CKD), especially end-stage kidney disease (ESKD), is associated with increased risk for cardiovascular events and all-cause mortality.
- Trial name
- NCT05557929
- Where
- Greece
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Chronic Kidney Disease Requiring Chronic Dialysis
Effects of Green Propolis Extract (EPP-AF) on Inflammation in Hemodialysis Patients.
End-stage chronic kidney disease is associated with the condition of chronic inflammation. Patients on hemodialysis are known to be predisposed to several factors that predispose to inflammation: dialysis membranes, central…
- Trial name
- NCT04072341
- Testing
- Propolis Period (Green Propolis 250mg/day), Control Period
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Intradialytic Hypotension, End-Stage Renal Disease Requiring Haemodialysis
Predictive Value of Carotid Ultrasonography for Intradialytic Hypotension
This multicenter, prospective observational study aims to evaluate the predictive value of carotid corrected flow time (FTc) and peak flow velocity variability (PFVV) for hypotension during maintenance hemodialysis.
- Conditions
- Intradialytic Hypotension, End-Stage Renal Disease Requiring Haemodialysis, Uremia; Chronic, Hemodialysis
- Trial name
- CUPID (NCT07033260)
- Testing
- Non-invasive Monitoring
- Where
- China
- Volunteers
- 183 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Secondary Hyperparathyroidism Due to Renal Causes, Chronic Kidney Diseases
Safety, Efficacy, PK and PD of CTAP101 (Calcifediol) ER Capsules for SHPT in HD Patients VDI
Safety, Efficacy, PK and PD of CTAP101 (calcifediol) ER Capsules for SHPT in HD Patients VDI
- Conditions
- Secondary Hyperparathyroidism Due to Renal Causes, Chronic Kidney Diseases, Vitamin D Deficiency, Stage 5 Chronic Kidney Disease
- Trial name
- NCT03602261
- Testing
- Calcifediol Oral Capsule
- Where
- 18 sites in United States
- Volunteers
- 44 people
- Sponsor
- OPKO Health, Inc.
Renal Failure Chronic Requiring Dialysis, Obstructive Sleep Apnea
Effects of Compression Stockings on Obstructive Sleep Apnea in Patients Under Hemodialysis
To study the effects of compression stockings on sleep apnea in hemodialysis patients with diagnosed obstructive sleep apnea. The rationale of this study consists in the fluid shift theory, which consists in the nocturnal rostral…
- Trial name
- EComStockOSA (NCT02503215)
- Testing
- Compression Stockings
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- University of Sao Paulo
Chronic Kidney Disease, Renal Failure Chronic Requiring Hemodialysis
Specific Enteral Nutrition in Malnourished, Dialysis Patients With Chronic Kidney Disease. Efficacy, Safety, Quality of Life
The objective of this unblinded study is to assess the nutritional effects of a 12 weeks administration of the specific enteral nutrition (SEN) RealDiet®Renal pockets, as well as the impact on the patients' quality of life.
- Conditions
- Chronic Kidney Disease, Renal Failure Chronic Requiring Hemodialysis, Severe Malnutrition, Tolerance
- Trial name
- AL-EN-PHED (NCT01946841)
- Testing
- RealDiet®Renal
- Where
- France
- Sponsor
- Lactalis
End-stage Renal Disease, Prevention of Thromboembolic Events
Study to Investigate the Safety of a Drug Called Osocimab at Low and High Doses in Adult Patients With Kidney Failure Requiring Regular Hemodialysis
In this study researchers want to learn about the safety of drug Osocimab at lower-dose and higher-doses in adult participants with kidney disease undergoing regular dialysis (a procedure that uses a machine to get rid of toxins…
- Conditions
- End-stage Renal Disease, Prevention of Thromboembolic Events, Hemodialysis, Hemodiafiltration
- Trial name
- CONVERT (NCT04523220)
- Testing
- BAY1213790 (Osocimab)
- Where
- 151 sites in United States, Australia and 17 more
- Volunteers
- 704 people
- Sponsor
- Bayer
Anemia, End Stage Renal Disease
16-Week Repeat Oral Dose Study of AKB-6548 for Anemia in Participants With End Stage Renal Disease (ESRD) Requiring Chronic Hemodialysis
The purpose of this study is to evaluate the hemoglobin response (efficacy), safety, and tolerability of orally administered AKB-6548 in participants with end stage renal disease undergoing chronic hemodialysis.
- Trial name
- NCT02260193
- Testing
- AKB-6548
- Where
- 16 sites in United States
- Volunteers
- 94 people
- Sponsor
- Akebia Therapeutics
Hyperkalemia, Chronic Kidney Disease Requiring Chronic Dialysis
Effect of Viscous Fiber on Postprandial Kalemic Response in Hemodialysis Patients
High blood potassium levels (hyperkalemia) is a major problem for people with kidney failure undergoing hemodialysis treatment. In order to reduce the risk of hyperkalemia, people with kidney failure are advised to limit or avoid…
- Trial name
- NCT05086185
- Testing
- Kalemic Response to Orange Juice, Kalemic Response to Orange Juice with Fiber
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Nevada, Reno
Chronic Kidney Disease Requiring Chronic Dialysis
Therapeutic Effects of Press Needle on 5-D Pruritus Scale in Hemodialysis Patients With Chronic Kidney Disease-Associated Pruritus
The goal of this clinical trial is to assess whether press needle acupuncture (PN) is more effective than sham press needle (sham PN) in reducing pruritus in patients with chronic kidney disease-associated pruritus (CKDaP)…
- Trial name
- NCT07030465
- Testing
- The press needle, antihistamine, and moisturizer therapy
- Where
- Indonesia
- Volunteers
- 38 people
- Sponsor
- Universitas Indonesia
Kidney Failure, Chronic, End Stage Renal Disease, Requiring Dialysis
FREEDOM: Following Rehabilitation, Economics and Everyday-Dialysis Outcome Measurements Study
Purpose The purpose of this study is to compare the economical impact and clinical parameters of short daily hemodialysis using the NxStage® System One hemodialysis device with thrice-weekly conventional in-center dialysis using…
- Trial name
- NCT00288613
- Where
- 41 sites in United States
- Volunteers
- 501 people
- Sponsor
- NxStage Medical
Vitamin D Deficiency, Renal Failure Chronic Requiring Hemodialysis
Sustainability of Vitamin D Levels After Repletion With Ergocalciferol In Chronic Kidney Disease Stage 5D
The prevalence of vitamin D deficiency increases as kidney function declines. As a result, many hemodialysis patients often have low levels of vitamin D.
- Trial name
- NCT01312441
- Testing
- Ergocalciferol
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- Albany College of Pharmacy and Health Sciences
End Stage Renal Disease, Chronic Kidney Disease Requiring Chronic Dialysis
Pumpkin Seed Oil as a Nutraceutical for Hemodialysis Patients
Patients with end-stage renal disease (ESRD) on maintenance hemodialysis experience chronic systemic inflammation, oxidative stress, and dyslipidemia, which together drive much of the excess cardiovascular morbidity and mortality…
- Conditions
- End Stage Renal Disease, Chronic Kidney Disease Requiring Chronic Dialysis, Inflammation, Oxidative Stress
- Trial name
- NCT07710183
- Testing
- Pumpkin Seed Oil 1000 mg, Standard hemodialysis care
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- Al-Mustansiriyah University
Chronic Kidney Disease Requiring Chronic Dialysis
Integrating BIA and eGFR for Nutritional Status in Hemodialysis Patients
This study looks at how measurements of body composition from Bioelectrical Impedance Analysis (BIA) and estimates of kidney function (eGFR) can be applied together to better assess the health of people on hemodialysis.
- Trial name
- NCT06873880
- Where
- Estonia
- Volunteers
- 30 people
- Sponsor
- University of Tartu
Chronic Kidney Disease Requiring Chronic Dialysis
FGF-23 and PTH in Hemodialysis Patients
In this pilot study the investigator will examine the levels of fibroblast growth factor (FGF-23) and parathyroid hormone (PTH) levels during hemodialysis therapy in 30 patients and assess the correlation between these parameters…
- Trial name
- NCT04350944
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Chronic Kidney Disease Requiring Chronic Dialysis
Activation of the Contact System and the Immune System in Patients With Chronic Kidney Disease.
Patients with end-stage renal disease undergoing hemodialysis (HD) are burdened with extremely high mortality rates (15% per year) and during the early stage (≤120days) the mortality rate is even higher (27% per year).
- Trial name
- AKIM-CKD (NCT05266092)
- Testing
- Observational study
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Chronic Kidney Disease Requiring Chronic Dialysis, Hemodialysis, Home
Body Composition Monitor Among Daily Home Dialysis With Low Flow Dialysate
The fluid overload measured by the Body Composition Monitor (BCM Fresenius Medical Care) is a new independent risk factor of mortality.
- Conditions
- Chronic Kidney Disease Requiring Chronic Dialysis, Hemodialysis, Home, Electric Impedance
- Trial name
- VOLODIA (NCT03994133)
- Testing
- Measurement of the hydration state by bio-impedance spectroscopy
- Where
- France
- Volunteers
- 85 people
- Sponsor
- University Hospital, Caen