Clinical trials: Chronic Low Back Pain, completed
Chronic Lower Back Pain
Mind Body Intervention for Chronic Lower Back Pain
This pilot study will evaluate the feasibility of having a non-behavioral health provider deliver a combination of manual therapy (MT) and cognitive behavioral therapy for pain (CBT-p).
- Trial name
- NCT01894282
- Testing
- Manual Therapy, Mind Body Intervention
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Canandaigua VA Medical Center
Low Back Pain
Validity and Predictive Value of Manual Clinical Test to Identify Symptomatic Segments in Lumbar Chronic Patients
This study evaluates the predictor value of manual test in lumbar chronic patients blocks. Bibliography has show limited evidence of clinical predictors in lumbar blocks.
- Trial name
- NCT02777450
- Testing
- lumbar facet block
- Where
- Spain
- Volunteers
- 93 people
- Sponsor
- Universidad de Zaragoza
Genetic Alteration, Low Back Pain
Genetic Alterations From Physical Therapy in Low Back Pain and Disc Degeneration
Background and Scientific Rationale: This prospective randomized controlled trial examines the combined effect of physiotherapy and vitamin D supplementation on pain, disability, interleukin-6 (IL-6) expression, and vitamin D…
- Conditions
- Genetic Alteration, Low Back Pain, Physiotherapy
- Trial name
- Low back pain (NCT07439874)
- Testing
- Interferential therapy
- Where
- Saudi Arabia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Tabuk
Chronic Low Back Pain
Investigation of Immediate, Short and Long Term Effects of Mulligan Mobilization With Movement Techniques in Nonspesific Chronic Low Back Pain
Introduction: Although the effectiveness of many mobilization methods in chronic low back pain (CLBP) was shown, these effects were not monitored in the long term.
- Trial name
- NCT04802850
- Testing
- Mulligan mobilization with movement
- Volunteers
- 36 people
- Sponsor
- Suleyman Demirel University
Low Back Pain, Disability Physical
The Impact Of Fascia Thickness on Chronic Low Back Pain
This study aimed to investigate the impact of lumbar perimuscular and subcutaneous zone thickness on pain, functionality, disability, and depression in individuals with chronic low back pain (CLBP).
- Conditions
- Low Back Pain, Disability Physical, Pain, Chronic
- Trial name
- NCT06572007
- Testing
- Ultrasound
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Okan University
Chronic Low Back Pain
Placebo In Chronic Back Pain (Phase 2)
This study is designed to examine brain properties for placebo response in chronic back pain patients. The investigators have preliminary data indicating that, in blinded clinical trial studies with neutral instructions regarding…
- Trial name
- PICP2 (NCT02986334)
- Testing
- Naproxen, Omeprazole
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Apkar Apkarian
Chronic Low Back Pain (Non-specific, Uncomplicated)
Effect of Massage on Chronic Low Back Pain
This study will evaluate the effectiveness of two types of massage therapy for treating chronic low back pain.
- Trial name
- NCT00371384
- Testing
- massage
- Where
- United States
- Volunteers
- 399 people
- Sponsor
- Kaiser Permanente
Major Depressive Disorder, Back Pain
Duloxetine Treatment of Major Depression and Chronic Low Back Pain For Older Adults
The following primary hypotheses will be tested: 1. During Step 1: Major Depressive Disorder (MDD) or Chronic Low Back Pain (CLBP) in < 40% of the initial 60 subjects treated with duloxetine (DUL) + Clinical Management(CM) during…
- Conditions
- Major Depressive Disorder, Back Pain, Aged
- Trial name
- ACHIEVE2 (NCT00696293)
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Chronic Pain, Low Back Pain
High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System
Study designed to compare the conventional stimulation programming versus the high frequency stimulation programming of the spinal cord stimulator for subjects who already have a spinal cord stimulator.
- Conditions
- Chronic Pain, Low Back Pain, Radiculopathy, Complex Regional Pain Syndrome (CRPS)
- Trial name
- HFSCS (NCT02265848)
- Testing
- High frequency stimulation, Low frequency stimulation
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The Center for Clinical Research, Winston-Salem, NC
Low Back Pain
Effect of Interferential l Therapy on Low Back Pain
Background: Chronic non-specific low back pain is defined as unknown mechanical musculoskeletal pain lasting more than 3 months.
- Trial name
- [PTREC] (NCT03961477)
- Testing
- Interferential therapy
- Where
- 2 sites in Egypt
- Volunteers
- 61 people
- Sponsor
- Ahlia University
Chronic Low-back Pain, Lumbal Disc Herniation
The Effect of Mulligan Mobilization Technique on Balance, Pain and Functionality in Patients With Chronic Low Back Pain
This study was aimed to investigate the effectiveness of mulligan mobilization technique on balance, pain and functionality in patients with chronic low back pain and to compare it with exercise.37 patients aged between 18-65 who…
- Conditions
- Chronic Low-back Pain, Lumbal Disc Herniation, Imbalance
- Trial name
- NCT05334394
- Testing
- Mulligan Technique, Exercise Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Medipol University
Chronic Pain, Chronic Lower Back Pain
Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain
Effective control of chronic pain is a top priority in the United States, as approximately 10% of adults have severe chronic pain most of which is chronic lower back pain (CLBP).
- Conditions
- Chronic Pain, Chronic Lower Back Pain, Back Pain, Opioid Use
- Trial name
- NCT04156802
- Testing
- Real TBS to the mPFC, Real TBS to the MC
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Wake Forest University Health Sciences
Chronic Low-back Pain
Reducing Sedentary Time in Chronic Low Back Pain: Sedentary Intervention Using Motivational Interviewing and Technology
This study will test the effects of a sedentary behavior intervention on pain processing, blood bio-markers and pain symptoms in individuals with chronic low back pain.
- Trial name
- SUMIT (NCT04257539)
- Testing
- Intervention to Reduce Sedentary Time
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Low Back Pain
Effects of Functional Inspiratory Muscle Training in Patients With Chronic Non-Specific Low Back Pain
The aim of the study was to investigate the effects of functional respiratory muscle training on diaphragm function, core stabilization, respiratory muscle strength, pain and functional status in patients with chronic…
- Trial name
- NCT06958744
- Testing
- Functional Inspiratory Muscle Training (FIMT) group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Uskudar University
Non Specific Low Back Pain
Efficacy of a Short Multidisciplinary Education and Rehabilitation Program for Patients With Subacute and Chronic Low Back Pain (LBP)
The main purpose of this study is to assess the clinical efficiency of an intervention including a short multidisciplinary program of education and rehabilitation and a personalized follow-up, in patients with subacute and…
- Trial name
- LOMBAFAST (NCT05261828)
- Testing
- Education and rehabilitation associated with personalized follow-up, Reassuring messages and advices
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Back Pain, Low Back Pain
Tapentadol Prolonged Release (PR) Versus Oxycodone/Naloxone Prolonged Release in Severe Chronic Low Back Pain With a Neuropathic Component.
This was a clinical effectiveness trial designed to compare the effectiveness, safety, and tolerability of treatment with tapentadol prolonged release with that of oxycodone/naloxone prolonged release in non-opioid pre-treated…
- Conditions
- Back Pain, Low Back Pain, Neuropathic Pain
- Trial name
- NCT01838616
- Testing
- Tapentadol Prolonged Release, Oxycodone/Naloxone Prolonged Release
- Where
- 50 sites in Austria, Germany and 2 more
- Volunteers
- 367 people
- Sponsor
- Grünenthal GmbH
Low Back Pain, Osteoarthritis
The Influence of Mindfulness Based Intervention on Pain Perception in Chronic Pain Patients
Background: Chronic pain is a common condition in the general population, causing great suffering in both physical and mental aspects.
- Trial name
- NCT01407549
- Testing
- mindfulness group meetings with psychologist
- Where
- Israel
- Volunteers
- 67 people
- Sponsor
- Meir Medical Center
Chronic Low Back Pain
Efficacy of Classification Based 'Cognitive Functional Therapy' in Patients With Non Specific Chronic Low Back Pain
A randomized controlled trial of the efficacy of classification based cognitive functional physiotherapy according to the system proposed by Peter O'Sullivan as compared to manual therapy and exercise in patients with non…
- Trial name
- NCT01129817
- Testing
- Cognitive Functional Therapy, Manual therapy and exercise
- Where
- Norway
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Chronic Nonspecific Low Back Pain
Total Contact Insole for Chronic Nonspecific Low Back Pain (LBP)
Non-specific low back pain is a common condition. Insoles are one of the many treatment form for chronic nonspecific LBP. The investigators hypothesized the contact total insole group will present pain reduction and functional…
- Trial name
- (LBP) (NCT03904940)
- Testing
- Total Contact Insole, Ethyl vinyl acetate flat insole
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Federal University of São Paulo
Low Back Pain
Effect of Milnacipran in Chronic Neuropathic Low Back Pain
Low back pain is a public health problem affecting between 70-85% of adults at some time in their life. This study is being done to study the safety and effectiveness of the drug Milnacipran in treating chronic low back pain.
- Trial name
- NCT01225068
- Testing
- Milnacipran
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwestern University
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