Clinical trials: Chronic Low Back Pain, completed
Low Back Pain
Effects of Self-Stretching Posture and Segmental Stabilization in Patients With Chronic Low Back Pain
Background: Low back pain is a major problem for public health that affects about 60-85% of the population at some point in life. Approximately 10-40% of individuals with low back pain develop the chronic form.
- Trial name
- NCT03128801
- Testing
- Global Stretching Program, Stabilization Exercises
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo
Chronic Low Back Pain, Negative Affectivity
Treating Negative Affect in Low Back Pain Patients
This study will examine how the use of antidepressant, physical therapy, and combination of both affects pain, function, and depression outcomes in chronic low back pain patients.
- Trial name
- TNA-LBP (NCT04747314)
- Testing
- Antidepressant, Enhanced Fear Avoidance Rehabilitation
- Where
- 3 sites in United States
- Volunteers
- 308 people
- Sponsor
- Ajay Wasan, MD, Msc
Chronic Low Back Pain
Interactive Voice Response (IVR)-Based Treatment for Chronic Low Back Pain
The proposed study will test how well an innovative method, interactive voice response (IVR), can be used for delivering an treatment for chronic low back pain.
- Trial name
- NCT01025752
- Testing
- Face to face cognitive behavior therapy, IVR based cognitive behavioral therapy
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- VA Office of Research and Development
Low Back Pain
Treatment of Chronic Low Back and Lower Extremity Pain
1. To demonstrate clinically significant improvements in patients undergoing lumbar interlaminar epidurals. Improvement will be assessed in relation to the clinical outcome measures of pain and function. 2.
- Trial name
- NCT00681447
- Testing
- Lumbar Interlaminar Epidural, Lumbar Interlaminar Epidural injection
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Pain Management Center of Paducah
Chronic Neck Pain, Chronic Low Back Pain
Group Acupuncture Therapy With Modified Yoga
Chronic pain is prevalent in the U.S., with impact on physical and psychological functioning as well as lost work productivity. Minority and lower socioeconomic populations have increased prevalence of chronic pain with less…
- Conditions
- Chronic Neck Pain, Chronic Low Back Pain, Osteoarthritis Pain
- Trial name
- GAPYOGA (NCT04296344)
- Testing
- Acupuncture Therapy Treatments, Yoga Therapy Sessions
- Where
- 3 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pain, Chronic, Neurologic Manifestations
Multimodal Intervention in Patients With Non-specific Chronic Low Back Pain: the HEALTHY BACK Project
Low back pain is one of the most common health problems seen in the primary care. Chronic low back pain is localized between the inferior limit of the ribs and the sacral region, and persist more than 12 weeks.
- Conditions
- Pain, Chronic, Neurologic Manifestations, Back Pain, Low Back Pain
- Trial name
- NCT06114264
- Testing
- Multimodal + Resistance Programs, Control group
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- IBS Granada
Low Back Pain, Low Back Pain, Recurrent
Structural White and Gray Matter Correlates of Impaired Muscle Control and Deficient Pain Processing
Although the cause of persistent non-specific low back pain (LBP) remains unknown, structural and functional alterations of the brain, alterations in the lumbar muscles and dysfunction of the central nervous system have been…
- Conditions
- Low Back Pain, Low Back Pain, Recurrent, Low Back Pain, Chronic, Healthy Volunteers
- Trial name
- B~Maps (NCT06143319)
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Ghent
Cognitive Dysfunction, Low Back Pain
Frequency of Cognitive Dysfunction in Patients With Chronic Low Back Pain
This study evaluates cognitive dysfunction status and related factors in patients with chronic low back pain over the age of 60.
- Trial name
- NCT06278467
- Testing
- visual pain scale (VASpain/fatigue), Beck depression index (BDI),, Pain catastrophizing scale, sleep quality with a single Likert type question in the Pittsburgh questionnaire, Roland Morris Disability Questionnaire, quality of life with Short Form-36 ( SF-36),
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Konya Beyhekim Training and Research Hospital
Chronic Low Back Pain
Patient Engagement Via Crowdsourcing
The study aims to advance pain research by exploring feasibility of crowdsourcing patient pain data via Amazon Mechanical Turk, the largest and most studied crowdsourcing platform in the U.S.
- Trial name
- PECS (NCT03264521)
- Testing
- Surveys
- Where
- United States
- Volunteers
- 8,193 people, healthy volunteers welcome
- Sponsor
- RAND
Chronic Low-back Pain
Brain Effects of Opiate Agonist and Antagonist
This study will look at the short-term effect of morphine on brain response to food.
- Trial name
- NCT04342130
- Testing
- Morphine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Chronic Low Back Pain
A Pilot Trial of IV Pamidronate for Low Back Pain
INTRODUCTION Pamidronate and other bisphosphonates (bisph) have an anti-nociceptive effect in animals. In humans, IV pamidronate is analgesic in patients affected by numerous painful conditions, including cancer bone pain…
- Trial name
- NCT01210599
- Testing
- Pamidronate
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pappagallo, Marco, M.D.
Low Back Pain
Bowen's Technique and Muscle Energy Technique on Hamstrings Tightness
The aim of this research is to find and compare the effect of Bowen's technique and Muscle energy technique on intensity of pain, active knee extension, limited forward bending and active straight leg raise on hamstrings…
- Trial name
- NCT04745858
- Testing
- Bowen's Technique, Muscle Energy Technique
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Chronic Low Back Pain
Tolerability, Safety and Pharmacokinetics of a Topical AB001 Patch in Healthy Subjects
The study evaluates the safety, tolerability and pharmacokinetics of single and repeated doses of topical AB001 patch and the bioavailability relative to the oral capsule and topical positive comparative patch.
- Trial name
- NCT03997734
- Testing
- AB001, oral capsule, positive comparative patch
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Frontier Biotechnologies Inc.
End Stage Renal Disease (ESRD), Peritoneal Dialysis Complication
The Effect of Exercise on Low Back Pain in Peritoneal Dialysis Patients
The goal of this randomized controlled trial is to find out if exercise can help reduce low back pain and improve quality of life in people receiving peritoneal dialysis (PD).
- Trial name
- NCT07000006
- Testing
- Home-based Core Stability Exercise
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Pardis Specialized Wellness Institute
Chronic Low Back Pain
Single Session Pain Psychology Treatment: Comparative Efficacy & Mechanisms
This study aims to compare the efficacy of a single session psychological treatment, "Empowered Relief" (ER), with the current standard of care, group Cognitive Behavioral Therapy (CBT) specifically on individuals with chronic…
- Trial name
- NCT03167086
- Testing
- "Empowered Relief" (ER), Cognitive Behavioral Therapy (CBT), Health Education (HE)
- Where
- United States
- Volunteers
- 263 people
- Sponsor
- Stanford University
Low Back Pain
True Functional Restoration and Analgesia in Non-Radicular Low Back Pain
You are asked to take part in this study because you have chronic, non-radicular low back pain. This study is done to investigate the pain relieving effects of the study drug Exalgo (Hydromorphone ER) for people who experience…
- Trial name
- Covidien (NCT01455519)
- Testing
- Hydromorphone ER, Sugar pill
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Shirley Ryan AbilityLab
Low Back Pain, Low Back Sprain
Usability of a Multimodal External Neuromodulatory Device to Relieve Acute Low Back Pain
Ten patients with acute or chronic low back pain will be invited to try a multimodal device for 20 minutes. Pain will be recorded prior to and after use, and feedback on the device will be elicited.
- Conditions
- Low Back Pain, Low Back Sprain, Low Back Pain, Recurrent
- Trial name
- NCT04494841
- Testing
- Duotherm VibraCool Back Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- MMJ Labs LLC
Low Back Pain
Photobiomodulation Therapy on Inflammatory Mediators on Low Back Pain
Low back pain (LBP) is ranked as one of the most prevalent health conditions. It is likely that some inflammatory mediators could be associated with pain and disability in these patients.
- Trial name
- NCT03859505
- Testing
- Active PBMT
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- Universidade Cidade de Sao Paulo
Low Back Pain
A Phase 3 Study of Tanezumab for Chronic Low Back Pain
This study will investigate the efficacy and safety of tanezumab 5 mg and 10 mg administered by subcutaneous injection seven times at 8 week intervals (56 weeks).
- Trial name
- TANGO (NCT02528253)
- Testing
- Tanezumab 5 mg SC, Tanezumab 10 mg SC, Tramadol PR oral
- Where
- 262 sites in United States, Canada and 7 more
- Volunteers
- 1,832 people
- Sponsor
- Pfizer
Chronic Low Back Pain, Chronic Low Back Pain (CLBP)
Bowen Therapy and McGill Stabilization Exercises in Chronic Low Back Pain
This randomized controlled trial aims to compare the effectiveness of Bowen Therapy combined with McGill stabilization exercises versus Bowen Therapy alone in individuals with chronic nonspecific low back pain.
- Trial name
- NCT07694219
- Testing
- Bowen Therapy + McGill Stabilization Exercise, Bowen Therapy
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Sehat Medical Complex
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