Clinical trials: Chronic Low Back Pain, completed
Low Back Pain
Selecting Effective Combinations of Treatment for Low Back Pain
Back pain is the #1 contributor to disability in the United States (US), and second only to hearing problems as a reason for new Veteran disability compensation.
- Trial name
- SELECT LBP (NCT03520387)
- Testing
- Lumbar medial branch nerve radiofrequency ablation (LRFA), Simulated LRFA with targeted steroid injections, AcTIVE-CBT
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- VA Office of Research and Development
Chronic Low-back Pain
The Effects of Different Exercise Approaches in Patients With Chronic Low Back Pain
Identification of the effects of yoga, stabilization exercise and aerobic exercise approaches on physical and cognitive variables in individuals with low back pain.
- Trial name
- NCT04000685
- Testing
- Yoga exercise program, Spinal stabilization exercise program, Aerobic walking program
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Hacettepe University
Chronic Low Back Pain
Efficacy of Education on Neurophysiology of Pain Combined to Hypnosis in Patients With Chronic Low Back Pain
Although education on neurophysiology of pain improves disability, there are limited effects in pain intensity. Hypnosis is an approach that has proven useful in pain intensity and psychosocial aspects in some chronic pain…
- Trial name
- NCT02638753
- Testing
- education, education combined with hypnosis
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Universidade Cidade de Sao Paulo
Central Nervous System Sensitization
Correlation Between Central Sensitization Inventory and Posturographic Data
To investigate the use of balance as a screening tool for Central Sensitization, a condition of the nervous system that is associated with the development and maintenance of chronic pain.
- Trial name
- NCT03058003
- Testing
- Posturography Evaluation, Central Sensitization Inventory
- Where
- 2 sites in United States, Australia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Caps Research Network
Chronic Low Back Pain, Post-traumatic Stress
Effectiveness of Pain Neuroscience Education (PNE) to Veterans With Post-Traumatic Stress and Low Back Pain
This trial compared traditional pain and stress education plus physical therapy to pain neuroscience education plus physical therapy in individuals with post-traumatic stress and chronic low back pain.
- Trial name
- NCT05086159
- Testing
- Pain Neuroscience Education, Exercise, Traditional Education
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Keller Army Community Hospital
Low Back Pain
Modic Changes and Associated Features in Southern European Chronic Low Back Pain Patients
To assess: a) The prevalence of Modic changes and other findings on lumbar magnetic resonance imaging (MRI), among Spanish adult chronic LBP patients, b) Patient characteristics and radiological findings associated with Modic…
- Trial name
- MODIC (NCT00478868)
- Where
- Spain
- Volunteers
- 487 people
- Sponsor
- Kovacs Foundation
Chronic Pain, Low Back Pain
A Prospective, Multi-site, Randomized, Sham-Controlled, Double-Blind Trial With One-Way Crossover Designed to Assess the Effectiveness and Safety of the Gimer NeuroBlock SCS Trialing System for the Treatment of Chronic Back Pain and/or Lower Limb Pain
This study is a prospective, multi-site, randomized, shamcontrolled, double-blind trial with one-way crossover designed to assess the effectiveness and safety of the Gimer NeuroBlock SCS Trialing System for the treatment of…
- Conditions
- Chronic Pain, Low Back Pain, Lower Limb Pain
- Trial name
- NCT04693650
- Testing
- NeuroBlock UHF stimulation
- Where
- 4 sites in Taiwan
- Volunteers
- 22 people
- Sponsor
- GiMer Medical
Musculoskeletal Pain, Low Back Pain
Effect of Strength Training for Chronic Low Back Pain Patients (IRMA20)
Low back pain (LBP) is common in the population and has great socioeconomic consequences for societies across Europe and the United States.
- Trial name
- IRMA20 (NCT03172962)
- Testing
- Strength training, Usual care (control)
- Where
- Spain
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- National Research Centre for the Working Environment, Denmark
Low Back Pain, Chronic Widespread Pain
13-year Follow-up of Women With Chronic Low Back Pain in Primary Care - a Prospective Longitudinal Cohort Study
Background: Low back pain (LBP) is among the main causes of long-term sickness absence and is associated with considerable costs for both the individual and society.
- Conditions
- Low Back Pain, Chronic Widespread Pain, Predictors, Pain
- Trial name
- NCT03974191
- Testing
- Change in function, activity, participation and other health related factors in CLBP and to identify predictors for pain, activity and work ability after 13 years.
- Where
- 3 sites in Sweden
- Volunteers
- 87 people
- Sponsor
- Vastra Gotaland Region
Chronic Low Back Pain
Meditation and Exercise to Treat Chronic Back Pain
This study evaluates the analgesic effect of a combination treatment of exercise and mindfulness based meditation in patients with chronic back pain.
- Trial name
- MedExT (NCT03324659)
- Testing
- Exercise and Meditation, Control
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Duquesne University
Peripheral Neuropathic Pain, Radiculopathy
Burst Spinal Cord Stimulation for Neuropathic Pain.
This study will evaluate the effect of Burst spinal cord stimulation (SCS) in the treatment of painful radiculopathy in lower extremity(ies) with or without lower back pain.
- Conditions
- Peripheral Neuropathic Pain, Radiculopathy, Lower Back Pain
- Trial name
- NCT03733886
- Testing
- Burst SCS (Abbott Proclaim IPG and single lead Abbott Octrode at level Th9/10)
- Where
- 2 sites in Norway, Sweden
- Volunteers
- 10 people
- Sponsor
- Oslo University Hospital
Low Back Pain
Corticospinal and Motor Behavior Responses After Physical Therapy Intervention in Patients With Chronic Low Back Pain.
This study aims to 1) determine the immediate effects of transcranial direct current stimulation (tDCS) on corticospinal excitability, lumbar multifidus muscle (LM) activation, as well as lumbar stability in patients with chronic…
- Trial name
- NCT05156242
- Testing
- Active-tDCS priming MCE, NMES priming MCE, Conventional physical therapy
- Where
- Thailand
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Chronic Low Back Pain, Chronic Leg Pain
Comparison of the Effects of Two Spinal Cord Stimulation (SCS) Therapies on Subject Reported Pain (BENEFIT-02)
A BIOTRONIK wearable stimulator will be utilized in order to investigate the effects of two study spinal cord stimulation (SCS) therapies on subject reported pain and paresthesia perception observed over 12 days of study…
- Trial name
- NCT03594266
- Testing
- Therapy A spinal cord stimulation parameter set using BIO-RNA system and associated components, Therapy B spinal cord stimulation parameter set using BIO-RNA system and associated components
- Where
- 18 sites in United States
- Volunteers
- 136 people
- Sponsor
- Biotronik, Inc.
Chronic Low Back Pain
Effects of a Myofascial Technique on Biomechanical Properties of the Lumbar Myofascia of Chronic Low Back Pain Adults
Non-specific low back pain is a worldwide health issue that remains poorly understood. Some authors have shown that the thoracolumbar fascia of low back pain adults presents changes in biomechanical properties.
- Trial name
- NCT04830566
- Testing
- Myofascial release technique, Simulated Myofascial Release technique
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- Université de Sherbrooke
Low Back Pain
Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain
The primary objective is to assess the efficacy of oxycodone/naloxone (OXN) for the management of opioid-induced constipation (OIC) compared to oxycodone controlled-release tablets (OXY) in subjects with moderate to severe low…
- Trial name
- NCT01427270
- Testing
- Oxycodone/Naloxone controlled-release, Oxycodone HCl controlled-release
- Where
- 194 sites in United States, Czechia and 2 more
- Volunteers
- 455 people
- Sponsor
- Purdue Pharma LP
Chronic Low Back Pain
Transcutaneous Electrical Nerve Stimulation and Interferential Currents in Chronic Low Back Pain
The purpose of this study was to compare the effects of the TENS and IFC in patients with non specific chronic low back pain.
- Trial name
- NCT01017913
- Testing
- TENS, Interferential currents
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- Federal University of São Paulo
Low Back Pain
Myofascial Release Technique vs Posterior-anterior Glide on Non-specific Low Back Pain
The objective of this randomized control trial is to determine the effectiveness of myofascial release in patients with nonspecific low back pain to improve Pain, Disability, and Quality of life This study is being conducted at…
- Trial name
- NCT05167435
- Testing
- Myofascial Release Experimental, Posterior-Anterior Glide
- Where
- 3 sites in Pakistan
- Volunteers
- 80 people
- Sponsor
- Dow University of Health Sciences
Back Pain, Lower Extremity Pain
The Feasibility of Using Neuroscience Education in Adults Over 65 Years Old With Chronic Low Back and/or Lower Extremity Pain
This is a pilot study to determine if neuroscience education is acceptable to adults over 65 and if it can have an impact on pain, pain beliefs and gait speed
- Trial name
- NCT02449876
- Testing
- Neuroscience Education
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- State University of New York - Upstate Medical University
Low Back Pain
Effectiveness of a Home Rehabilitation Program vs an e-Health Program in Patients With Chronic Low Back Pain
The main objetive of this study is to analyze the effectiveness of a home rehabilitaton program vs a e-Health program. Therapeutic approach will be by electroanalgesia and exercise of patients with chronic low back pain.
- Trial name
- NCT03469024
- Testing
- Home Rehabilitation Program, e-Health program
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Universidad de Almeria
Chronic Low-back Pain
A Study Protocol Comparing a Home Rehabilitation Program Versus e-Health Program in Low Back Pain
The aim of this randomized controlled trial is to evaluate the feasibility and effectiveness of providing an e-Health rehabilitation program through a web platform performing electroanalgesia and an exercise program following the…
- Trial name
- NCT04283370
- Testing
- Home Rehabilitation Program, e-Health program
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Universidad de Almeria
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