Clinical trials: Chronic Low Back Pain, completed
Low Back Pain
Pain Neuroscience Education and Gradual Exposure to Exercise in Factory Workers With Chronic Low Back Pain
This study aims to compare the effectiveness of a pain neuroscience education (PNE) based programe and gradual exposure to exercise versus pilates on disability levels associated with chronic low back pain in factory workers.
- Trial name
- NCT04191317
- Testing
- Pain Neuroscience Education and gradual exposure, Pilates and postural education
- Where
- Portugal
- Volunteers
- 37 people
- Sponsor
- Aveiro University
Chronic Low-back Pain
Myofascial Trigger Point Release and Paced Breathing Training for Chronic Low Back Pain
A study to explore whether two different treatment approaches, myofascial trigger point release and core stabilization exercises, both with and without additional paced breathing training, can help patients with chronic low back…
- Trial name
- NCT04107597
- Testing
- Core stabilization exercises, Core stabilization exercises and paced breathing training, Myofascial trigger point release
- Where
- Germany
- Volunteers
- 124 people
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Chronic Low-back Pain, Chronic Pain
HOnest Placebos With Explanations: Evaluating Open-Label Placebos for Chronic Pain
The goal of this clinical trial is to examine the effect of rationale condition when taking open-label placebos on pain by 1) comparing each rationale to the no rationale control condition and the no treatment control condition…
- Trial name
- HOPE (NCT06931158)
- Testing
- Standard Rationale, Mindfulness, Control Rationale
- Where
- United States
- Volunteers
- 327 people
- Sponsor
- Rhode Island Hospital
Chronic Low-back Pain
Effectiveness of Cat-Cow Yoga in Managing Chronic Low Back Pain
A randomized control trial is planned to investigate the effectiveness of Cat-Cow yoga as a treatment for chronic low back pain CLBP.
- Trial name
- NCT04723225
- Testing
- Cat-Cow Yoga
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Karachi
Chronic Low Back Pain
tDCS for Chronic Low Back Pain
The goal of this study is to investigate the role of central neural pathways in mediating chronic pain. The aim of the study is to test the effect of stimulating brain regions that are part of a network underlying central pain…
- Trial name
- NCT02771990
- Testing
- transcranial direct current stimulation
- Volunteers
- 30 people
- Sponsor
- Providence VA Medical Center
Low Back Pain
Efficacy and Safety of Oxycodone/Naloxone Controlled-release Tablets (OXN) Compared to Placebo in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain
The primary objective of this study is to assess the efficacy and safety of OXN compared to placebo in opioid-experienced subjects with moderate to severe pain due to chronic low back pain who require around-the-clock opioid…
- Trial name
- NCT01358526
- Testing
- Oxycodone/Naloxone Controlled-release
- Where
- 151 sites in United States
- Volunteers
- 1,095 people
- Sponsor
- Purdue Pharma LP
Low Back Pain
Comparison of Prolotherapy and Rehabilitation Treatments in Low Back Pain (CPRTLBP)
Chronic low back pain (CLBP) represents one of the leading causes of long-term disability among adults and places a substantial strain on healthcare systems globally.
- Trial name
- CPRTLBP (NCT07399145)
- Testing
- Prolotherapy, Balneotherapy plus Physiotherapy, Physiotherapy
- Where
- Romania
- Volunteers
- 84 people
- Sponsor
- Balnear and Rehabilitation Sanatorium Techirghiol
Recurrent Low Back Pain, Persistent Low Back Pain
Chiropractic Maintenance Care of Persistent or Recurrent Low Back Pain
As low back pain is often a recurrent and sometime persistent problem, research into prevention is important. Chiropractors have traditionally treated patients with maintenance care, which means that patients are seen on a…
- Conditions
- Recurrent Low Back Pain, Persistent Low Back Pain, Chronic Low Back Pain
- Trial name
- NCT01539863
- Testing
- maintenance care, Treatment as needed
- Where
- Sweden
- Volunteers
- 328 people
- Sponsor
- Karolinska Institutet
Low Back Pain
BackToBasic: Infliximab in Chronic Low Back Pain and Modic Changes
Low-Back Pain (LBP) is the leading cause of disability worldwide. Even though LBP relates to different underlying pathologies, there are a substantial number of patients with chronic complaints that have vertebral bone marrow…
- Trial name
- NCT03704363
- Testing
- Biosimilar Infliximab
- Where
- 6 sites in Norway
- Volunteers
- 128 people
- Sponsor
- Oslo University Hospital
Lower Back Pain Chronic, Lumbar Disc Disease
PRP Spinoplasty for Chronic Low Back Pain With Multiple Pathologies: A Quasi-Experimental Study
This study aimed to evaluate the efficacy and safety of a comprehensive, multi-target injection protocol, termed 'PRP Spinoplasty,' for managing chronic LBP stemming from concurrent lumbar disc and facet joint disease with…
- Conditions
- Lower Back Pain Chronic, Lumbar Disc Disease, Facet Joint Arthritis
- Trial name
- NCT07268885
- Testing
- Spinoplasty with Platelet Rich Plasma
- Where
- Palestinian Territories
- Volunteers
- 35 people
- Sponsor
- Allmed Medical Center
Acute Low Back Pain, Chronic Low Back Pain
French Validation Orebro Musculoskeletal Pain Screening Questionnaire (OMPSQ) Questionnaire
Low back pain is a very common disease. Among the persons suffering of acute low back pain, about 10% are at risk of developping chronic pain.
- Trial name
- NCT00706043
- Volunteers
- 100 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Pain, Osteoarthritis
An Open-label Extension Study With Flexible Dosing of Extended-release (ER) Tapentadol (CG5503) to Treat Patients With Moderate to Severe Chronic Pain
The purpose of the study is to assess the long-term safety profile of Tapentadol (CG5503) extended release (ER) at dosages ranging from 100 to 250 mg twice a day in treating patients with moderate to severe chronic pain over a…
- Conditions
- Pain, Osteoarthritis, Low Back Pain
- Trial name
- NCT00487435
- Testing
- Tapentadol (CG5503) Extended Release (ER)
- Where
- 148 sites in United States, Australia and 2 more
- Volunteers
- 1,166 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Chronic Non-specific Low Back Pain
Effect of Yoga Vs. Stretching on Chronic Back Pain
This study will compare the effectiveness of yoga classes, exercise classes, and a self-care book in the management of pain and function for people with low back pain.It will also for physical, psychological and physiological…
- Trial name
- YES (NCT00447668)
- Testing
- Yoga, Exercise, Self-care book recommendations
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Kaiser Permanente
Chronic Low-back Pain, Low Back Pain
Virtual Reality-based Induction to Improve Positive Body Image in Low Back Pain Patients.
The aim of this study is to examine the effects of a Virtual Reality-based induction to modify positive body image in individuals with low back pain.
- Trial name
- NCT06054074
- Testing
- Positive Appreciation of Body Functionality Induction, Negative Appreciation of Body Functionality Induction
- Where
- Spain
- Volunteers
- 53 people
- Sponsor
- University of Valencia
Quality of Sleep, Subacute or Chronic Low Back Pain
Association Between Low Back Pain and Quality of Sleep
A prospective study to assess the association between the change in quality of sleep and the change in intensity of pain in Spanish patients seen for subacute or chronic low back pain.
- Conditions
- Quality of Sleep, Subacute or Chronic Low Back Pain, Disability, Catastrophizing
- Trial name
- NCT00906152
- Where
- 2 sites in Spain
- Volunteers
- 437 people
- Sponsor
- Kovacs Foundation
Low Back Pain, Hamstring Pulled
Immediate Effect of Mulligan Two Leg Rotation and Bent Leg Raise Techniques on Hamstring Tightness
The aim of this study is to compare the immediate effect of mulligan's two leg rotation and bent leg raise for hamstring tightness, core muscle weakness in chronic low back pain, lumbar Range of motion.
- Trial name
- NCT04747925
- Testing
- Mulligan two leg rotation core muscle strengthning exercises, mulligan bent leg raise technique, core muscle strengthning exercises
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Riphah International University
Chronic Low Back Pain
EFFects of EXPosure and Cognitive-behavioural Therapy for Chronic BACK Pain
The overall aim of the present study is to compare two different psychological methods, Cognitive Behavioural Therapy (CBT) and Graduated Exposure in vivo (EXP) in the treatment of chronic back pain with regard to effectiveness…
- Trial name
- EFFECT-BACK (NCT05294081)
- Testing
- Exposure therapy, Cognitive behavioral therapy
- Where
- 5 sites in Germany
- Volunteers
- 392 people
- Sponsor
- University of Kaiserslautern-Landau
Neck Pain, Low Back Pain
PNE Effectiveness Cluster Trial
This is a cluster randomized trial that involves training regions of physical therapy clinics to use pain neuroscience education or continue with usual care.
- Conditions
- Neck Pain, Low Back Pain, Chronic Pain
- Trial name
- PNE (NCT03168165)
- Testing
- Pain neuroscience education training
- Where
- 41 sites in United States
- Volunteers
- 316 people
- Sponsor
- University of Utah
Chronic Nonspecific Low-back Pain
Effect of High-power Laser Acupuncture on Fatigue and Proprioception in Low Back Pain
To investigate the effect of high-intensity laser acupuncture on fatigue, proprioception, back pain and Pain self-efficacy in patients with chronic nonspecific low back pain (CNLBP).
- Trial name
- NCT07196709
- Testing
- high-power laser acupuncture and the exercise program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Chronic Low-back Pain (cLBP)
Biopsychosocial Model-based Care Versus Routine Physical Therapy in Chronic Back Pain
Chronic low back pain (CLBP) is a multifactorial condition influenced by physical, psychological, and social factors. Conventional physical therapy primarily targets biomechanical impairments, often neglecting psychosocial…
- Trial name
- NCT07280806
- Testing
- Biopsychosocial model based care, Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Lahore University of Biological and Applied Sciences
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