Clinical trials: Chronic Low Back Pain, completed
Chronic Low Back Pain
Study of the Efficacy and Safety of Bupivacaine TTS Patch in Patients With Chronic Low Back Pain
This study will evaluate the efficacy and safety of Bupivacaine TTS (Bupivacaine patch) compared to placebo in patients with chronic low back pain.
- Trial name
- NCT01096966
- Testing
- Bupivacaine TTS (Bupivacaine Patch)
- Where
- 21 sites in United States
- Volunteers
- 263 people
- Sponsor
- Durect
Chronic Pain
Study to Evaluate the Effectiveness of DRG Stimulation for Discogenic Low Back Pain
The purpose of this prospective post market observational pilot study is to evaluate the effect of DRG stimulation in the management of chronic discogenic pain in subjects who are refractory to other available treatments.
- Trial name
- NCT02587637
- Testing
- Dorsal root ganglion (DRG) stimulation
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Abbott Medical Devices
Chronic Low Back Pain
Efficacy of Education on Neurophysiology of Pain Combined to Hypnosis in Patients With Chronic Low Back Pain
Although education on neurophysiology of pain improves disability, there are limited effects in pain intensity. Hypnosis is an approach that has proven useful in pain intensity and psychosocial aspects in some chronic pain…
- Trial name
- NCT02638753
- Testing
- education, education combined with hypnosis
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Universidade Cidade de Sao Paulo
Low Back Pain
Duration of Spinal Manipulation Effects as Influenced by Orthotics
Purpose of study: To assess the effects of wearing custom orthotics as opposed to placebo foot inserts on the duration of chiropractic correction of spinal fixations and muscle imbalances using applied kinesiology techniques.
- Trial name
- NCT01704807
- Testing
- foot orthotics
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Logan College of Chiropractic
Low Back Pain
Surface Electromyography in Stratifying Chronic Low Back Pain.
Surface Electromyography can be utilised to detect normal muscle electrical activity during maximum forward flexion termed Flexion Relaxation Response (FRR)
- Trial name
- NCT04960358
- Testing
- Surface Electromyography
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Chronic Low-back Pain
Persica 002 Phase 1b PP353 vs Placebo in the Treatment of Low Back Pain
A Phase 1b study to investigate the efficacy of PP353 compared to placebo in the treatment of chronic low back pain associated with bone oedema.
- Trial name
- NCT04238676
- Testing
- PP353
- Where
- 10 sites in Denmark, New Zealand and 2 more
- Volunteers
- 43 people
- Sponsor
- Persica Pharmaceuticals Ltd
Low Back Pain
Dose of Spinal Manipulation for Chronic Low Back Pain
This study will determine the number of visits to a chiropractor for spinal manipulation, light massage, and ultrasound necessary for optimal relief of chronic low back pain.
- Trial name
- NCT00376350
- Testing
- Spinal Manipulation, Light Massage, Pulsed Ultrasound
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Western States
Low Back Pain
Efficacy of Acupuncture for Chronic Low Back Pain
This is a trial to clarify the extent to which acupuncture needling can diminish the effect of chronic back pain on patient functioning and symptoms.
- Trial name
- NCT00065585
- Testing
- Accupuncture
- Where
- 2 sites in United States
- Volunteers
- 640 people
- Sponsor
- Kaiser Permanente
Chronic Low Back Pain
Five-Plus Year Follow-Up of SMART Randomized Controlled Trial
The objective of this study is to evaluate long-term ongoing effectiveness of the Intracept Intraosseous Nerve Ablation System for the treatment of chronic low back pain.
- Trial name
- SMART (NCT03997825)
- Testing
- Basivertebral Nerve (BVN) Ablation
- Where
- 13 sites in United States
- Volunteers
- 117 people
- Sponsor
- Relievant Medsystems, Inc.
Low Back Pain, Chronic Pain
Cognitive Muscular Therapy for Low Back Pain
The primary aim of this study is to adapt Cognitive Muscular Therapy so that it can be used to manage chronic low back pain. A secondary aim is to understand the potential therapeutic benefit of this intervention.
- Conditions
- Low Back Pain, Chronic Pain, Muscle Tightness
- Trial name
- CMT-LBP (NCT05611476)
- Testing
- Cognitive Muscular Therapy for low back pain
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Salford
Chronic Low Back Pain
Study to Evaluate the Safety and Efficacy of ABT-712 in Subjects With Moderate to Severe Chronic Low Back Pain (CLBP)
The primary purpose of the study was to test the efficacy of 2 tablets (twice daily) of ABT-712, compared to placebo, administered over a 4-week period in participants with moderate to severe mechanical chronic low back pain…
- Trial name
- NCT00761150
- Testing
- ABT-712
- Where
- 32 sites in United States
- Volunteers
- 308 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Low Back Pain, Chronic Low-back Pain
Effect of Diaphragm Manual Therapy With Conventional Physical Therapy in Chronic Non-Specific Low Back Pain Patients
A randomized single-blind clinical study will be performed. A sample size of 34 patients including only male gender, will be taken from various clinical settings of Faisalabad.
- Trial name
- NCT05299216
- Testing
- Manual Diaphragm Technique, Conventional Physical Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 34 people
- Sponsor
- University of Faisalabad
Low Back Pain, Back Pain
Evaluation of Efficacy and Comfort: A Trial on the Incrediwear Back Brace in Patients With Chronic Lower Back Pain
The investigators hypothesize that the utilization of Incrediwear's Back Brace, compared to a sham brace and a standard-issue brace, will lead to better brace adherence, increased patient satisfaction, reduced pain medication…
- Trial name
- NCT06126887
- Testing
- Incrediwear Daytime Back Brace, Control Daytime Back Brace, Incrediwear 24 Hour Back Brace
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
Low Back Pain
Osteopathic Treatment of Low Back Pain
Eighty percent of Canadians experience low back pain (LBP) at some point in their life (Waddell, 1987), with a point prevalence of up to 30 percent (O'Sullivan, 2005; Waddell, 1987).
- Trial name
- NCT00883987
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mary Lynch
Low Back Pain
Therapeutic Effects of Horticulture on Anterior Cingulate Cortex Activation in People With Chronic Low Back Pain
Chronic low back leads to a significant socio-economic burden. It is associated with physical and psychosocial deconditioning. Even a short "nature experience" has positive effects on the affective and cognitive factors involved…
- Trial name
- HORTICARE (NCT04656158)
- Testing
- Physical activity involving exposure to nature: Therapeutic horticulture
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Non-specific Low-Back Pain, Chronic Non-specific Neck Pain
Diaphragmatic Breathing Training in Chronic Spinal Pain
The goal of this clinical trial is to learn whether adding breathing training to an exercise program can improve pain, mood, and thinking skills in adults with chronic spinal pain.
- Trial name
- NCT07539116
- Testing
- Structured Exercise program, Diaphragmatic Breathing Training
- Where
- 2 sites in Greece
- Volunteers
- 183 people
- Sponsor
- Democritus University of Thrace
Chronic Pain, Fibromyalgia
Developing an Activity Pacing Framework: Feasibility and Acceptability
This study explores whether it is feasible to use a newly developed activity pacing framework to standardise how activity pacing is instructed by healthcare professionals in rehabilitation programmes for patients with chronic…
- Conditions
- Chronic Pain, Fibromyalgia, Chronic Fatigue Syndrome, Chronic Low Back Pain
- Trial name
- NCT03497585
- Testing
- Activity pacing framework
- Where
- United Kingdom
- Volunteers
- 112 people
- Sponsor
- Pennine Acute Hospitals NHS Trust
Back Pain Lower Back Chronic
Yoga Dosing Study for Chronic Low Back Pain
A 12-week randomized controlled trial (RCT) for chronic low back pain in predominantly minority populations comparing yoga classes once/week vs. twice/week.
- Trial name
- YLBP2 (NCT01761617)
- Testing
- Yoga class once per week, Yoga class twice per week
- Where
- 6 sites in United States
- Volunteers
- 96 people
- Sponsor
- Boston Medical Center
Low Back Pain
Myofascial Release Technique vs Posterior-anterior Glide on Non-specific Low Back Pain
The objective of this randomized control trial is to determine the effectiveness of myofascial release in patients with nonspecific low back pain to improve Pain, Disability, and Quality of life This study is being conducted at…
- Trial name
- NCT05167435
- Testing
- Myofascial Release Experimental, Posterior-Anterior Glide
- Where
- 3 sites in Pakistan
- Volunteers
- 80 people
- Sponsor
- Dow University of Health Sciences
Chronic Low Back Pain
A Pilot Study of Motor Control Exercise and Patient Education for the Management of Chronic Low Back Pain in Rural Nigerian Community.
The main purpose of this pilot single-blind randomized clinical trial is to assess the feasibility of implementing motor control exercise and patient education for the management of chronic low back pain (CLBP) in a low resource…
- Trial name
- NCT03398174
- Testing
- Motor Control Exercise, Patient Education
- Where
- Nigeria
- Volunteers
- 30 people
- Sponsor
- Bayero University Kano, Nigeria