Clinical trials: Chronic Low Back Pain, completed
Chronic Pain, Low Back Pain
High Level Pulsed Heat Versus Low Level Steady Heat in Subjects With Chronic Low Back Pain
This study is a double blinded randomized active placebo controlled trial in subjects with chronic low back pain. The trial compares pain relief by a device that delivered high level pulsed heat (45 °C) to pain relief delivered…
- Conditions
- Chronic Pain, Low Back Pain, Heat, Analgesia
- Trial name
- NCT04109703
- Testing
- High Level Pulsed Heat delivered by Generation 5 devices from Soovu Labs Inc., Low Level (37 degrees C) delivered by the control device Generation 5 devices from Soovu Labs Inc.
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soovu Labs Inc.
Chronic Low-back Pain, Hip Impairments
Manual Therapy and Strengthening for the Hip in Older Adults With Chronic Low Back Pain
Older adults with chronic low back pain (LBP) are at a greater risk for disability, loss of independence, and lower quality of life.
- Conditions
- Chronic Low-back Pain, Hip Impairments, Hip-spine Syndrome, Osteoarthritis
- Trial name
- MASH (NCT04009837)
- Testing
- Hip-focused rehabilitation intervention, Spine-focused rehabilitation intervention
- Where
- 3 sites in United States
- Volunteers
- 184 people
- Sponsor
- University of Delaware
Low Back Pain, Low Back Pain, Recurrent
Structural White and Gray Matter Correlates of Impaired Muscle Control and Deficient Pain Processing
Although the cause of persistent non-specific low back pain (LBP) remains unknown, structural and functional alterations of the brain, alterations in the lumbar muscles and dysfunction of the central nervous system have been…
- Conditions
- Low Back Pain, Low Back Pain, Recurrent, Low Back Pain, Chronic, Healthy Volunteers
- Trial name
- B~Maps (NCT06143319)
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Ghent
Chronic Low Back Pain
Pain Neuroscience Education Delivered During Aerobic Exercise Versus Exercise Alone
Chronic musculoskeletal pain is a common health condition that reduces quality of life and increases disability. Pain neuroscience education (PNE) has shown positive effects on pain perception, beliefs, and function, especially…
- Trial name
- PNE-MOVE (NCT07152171)
- Testing
- Pain Neuroscience Education During Aerobic Exercise, Aerobic Exercise Alone
- Where
- Chile
- Volunteers
- 24 people
- Sponsor
- University of Chile
Low Back Pain
Biomechanical Gait Analysis in Low Back Pain
The goal of this observational case-control study is to learn whether low back pain is associated with changes in gait and related clinical characteristics in adults over 18 years old.
- Trial name
- LBP (NCT07417345)
- Where
- Spain
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Arrate Pinto Carral
Pain, Back Pain
Development of STEPPT
This 6-month pilot study aims to assess the feasibility, acceptability, and estimate effect sizes of the pilot STEPPT intervention for addressing ethnic disparities in physical therapy referrals and adherence between Hispanic and…
- Conditions
- Pain, Back Pain, Low Back Pain, Chronic Pain
- Trial name
- STEPPT PILOT (NCT06835439)
- Testing
- STEPPT Pilot, Standard Care (Control)
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- San Diego State University
Back Pain Lower Back Chronic, Insomnia
Melatonin fOr CHronic bAck Pain (The MOCHA Trial)
According to the World Health Organization (WHO) Global Burden of Disease study, back pain is one of the conditions impacting disability the most worldwide.Pain medication use in patients with chronic back pain is substantial…
- Trial name
- MOCHA (NCT06476392)
- Testing
- Melatonin 10 MG
- Where
- Denmark
- Volunteers
- 220 people
- Sponsor
- Odense University Hospital
Low Back Pain
High Intensity Training With Non-specific Chronic Low Back Pain
Low back pain is a common disorder, occurring worldwide in both males and females in all age groups1. The prevalence is higher in females and the incidence peaks between 30 and 65 years.
- Trial name
- LBP-HIT (NCT02786316)
- Testing
- HIT program, conventional rehabilitation program
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Hasselt University
Chronic Low-back Pain
VANISH for Chronic Low Back Pain
The program, called TMC-CP01, will use a combination of virtual reality, biofeedback, and psychological exercises to manage pain associated with Chronic Low Back Pain.
- Trial name
- VANISH (NCT04236804)
- Testing
- Flowly (TMC-CP01)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ajay Wasan, MD, Msc
Sub-Acute and Chronic Low Back Pain
Individualized Chiropractic and Integrative Care for Low Back Pain
This study proposes to compare two innovative treatment approaches for LBP, both of which focus on delivering individualized care through evidence-based, clinical care pathways.
- Trial name
- NCT00567333
- Testing
- Chiropractic care, Multidisciplinary, integrative care
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Northwestern Health Sciences University
Low Back Pain, Connective Tissue Defect (Diagnosis)
Effect of Treatment on Connective Tissue in Low Back Pain
The purpose of the study is to investigate the effects of instrument assisted soft tissue mobilization (IASTM) and kinesiology taping (KT) that are additional treatment to the conservative treatment for the lumbar region and…
- Trial name
- NCT04762563
- Testing
- IASTM application, Kinesio Tape® Tex Gold)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Okan University
Pain
Chronic Low Back Pain and Meditation
The purpose of this research study is to see if and how mindfulness meditation affects pain. Specifically, we are interested in assessing if mindfulness is associated with the release of naturally occurring opiates in the body…
- Trial name
- NCT04034004
- Testing
- Mindfulness, Naloxone, Saline
- Where
- 2 sites in United States
- Volunteers
- 88 people
- Sponsor
- University of California, San Diego
Low Back Pain
Sensory Effects of Oral Opioid Treatment in Patients With Chronic Low Back Pain
Chronic low back pain (CLBP) afflicts up to 50 million U.S. adults and is a primary cause of disability and reduced quality of life.
- Trial name
- NCT02824276
- Testing
- Oxycodone or morphine sulfate immediate release (MSIR)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Brigham and Women's Hospital
Chronic Low-back Pain
Exercise, PNE and Cognitive Training in Individuals With Chronic Low Back Pain
This study aims of to investigate whether combining cognitive training to exercise and Pain Neuroscience Education will contribute to reduction of pain and associated symptoms (i.e., catastrophizing, fear of movement, disability)…
- Trial name
- NCT05777343
- Testing
- Experimental, Exercise and PNE, Cognitive training
- Where
- Portugal
- Volunteers
- 99 people
- Sponsor
- Aveiro University
Osteoarthritis, Hip, Osteoarthritis, Knee
A Study to Evaluate Long-Term Safety of Multiple Doses of Tapentadol (CG5503) Prolonged-Release (PR) and Oxycodone Controlled-Release (CR) in Patients With Chronic Pain
The purpose of this study is to evaluate the safety profile of tapentadol (CG5503) PR at doses of 100 mg - 250 mg administered twice daily over a maximum one year period to patients with at least a 3-month history of low back…
- Conditions
- Osteoarthritis, Hip, Osteoarthritis, Knee, Lower Back Pain, Pain
- Trial name
- NCT00361504
- Testing
- Oxycodone CR, Tapentadol (CG5503) ER
- Where
- 52 sites in United States, Canada
- Volunteers
- 1,123 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Pain, Chronic Pain
Effect of Pulse Width With Spinal Cord Stimulation
The primary objective of this study is to assess the effects of varying pulse width in suprathreshold dorsal column stimulation in patients with low back pain.
- Conditions
- Pain, Chronic Pain, Back Pain
- Trial name
- NCT00399516
- Testing
- Precision
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Boston Scientific Corporation
Chronic Low-back Pain, Myofascial Pain
Ultrasound Imaging for Myofascial Pain
The goal of this observational study is to develop and validate a biomarker for lumbar myofascial pain (MP) based on ultrasound obtained measurements of the lumbar muscles and fascia.
- Trial name
- NCT05928884
- Testing
- There is no intervention. It is a phenotyping study only
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Osteoporosis, Low Back Pain
Comparison of a Weight Bearing and a Non-weight Bearing Protocol on Osteoporotic Women With Chronic Low Back Pain
The effect of exercising in different body positions on bone growth in osteoporotic women is known, but its effect on their function, low back pain, lumbar range of motion and quality of life remains unknown.
- Trial name
- NCT03747289
- Testing
- performing exercises in a weight bearing posture, performing exercises in a non weight bearing posture
- Where
- Israel
- Volunteers
- 53 people
- Sponsor
- Bait Balev Hospital
Chronic Low-back Pain
The Effect of an Acute Bout of Exercise on Pain Sensitivity and Clinical Pain in Adults With Chronic Low Back Pain
The goal of this interventional study is to investigate the efficacy of an acute bout of exercises on pain sensitivity (primary aim) and clinical pain intensity (secondary aim) among adults with Chronic Low Back Pain.
- Trial name
- NCT05779748
- Testing
- Single bout of exercise
- Where
- Saudi Arabia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Taif University
Chronic Low-back Pain
Comparative Effects of Mulligan Straight Leg Raise Technique Versus Slump Stretching on Pain, Disability and Hip Range of Motion in Patients With Chronic Low Back Pain.
The goal of this clinical trial is to examine the effect of mulligan straight leg raise versus slump stretching on pain, disability and hip range of motion in patient with low back pain. .
- Trial name
- NCT05779891
- Testing
- Mulligan Traction Straight Leg Raise Technique, Slump Stretching
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
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