Clinical trials: Chronic Low Back Pain, completed
Back Pain Lower Back Chronic
Caudal Epidural Injection of Dextrose For Low Back Pain
Objective: The purposes of the study are to 1. Explore the immediate and short term (to 48 hour) analgesic potential of epidural D5W in comparison to normal saline. 2.
- Trial name
- NCT01547364
- Testing
- Saline, Dextrose
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Smigel, Liza, M.D.
Low Back Pain
Specific or Non-Specific Manipulation for Patients With Back Pain
We aim to evaluate the long-term effects of 10 sessions of spinal manipulative therapy applied in a vertebral region-specific or region nonspecific level immediately after treatment and 3 and 6 months after randomization.
- Trial name
- NCT02883634
- Testing
- Specific manipulation, Non-specific manipulation
- Where
- Brazil
- Volunteers
- 148 people
- Sponsor
- Universidade Cidade de Sao Paulo
Chronic Low Back Pain
Digital Therapeutics (DTx) for Pain: Pilot Study of a Virtual Reality Software for Chronic Pain
Prospective, randomised, double-blind, 3-arm parallel group comparison of 2 different virtual reality softwares and standard care.
- Trial name
- VIRPI (NCT04225884)
- Testing
- DTx for pain software, Control software, Standard care
- Where
- Finland
- Volunteers
- 34 people
- Sponsor
- Orion Corporation, Orion Pharma
Nonspecific Chronic Low Back Pain
Body and the Brain: Cortical Reactivity and Cognitive-Affective Regulation to Experimental Pain.
The purpose of this cross-sectional study is to compare cortical reactivity and cognitive-affective regulation in response to experimental pain between healthy controls and individuals with non-specific chronic low back pain.
- Trial name
- NCT07896785
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Chronic Low Back Pain, Chronic Sciatica
A Zhineng Qigong Intervention for Patients With Chronic Low Back Pain and/or Leg Pain
The purpose of this study is to evaluate a Zhineng Qigong intervention for patients with chronic low back pain and/or leg pain, and to test feasibility aspects.
- Conditions
- Chronic Low Back Pain, Chronic Sciatica, Lumbar Spinal Stenosis, Lumbar Disc Herniation
- Trial name
- NCT04520334
- Testing
- Zhineng Qigong intervention
- Where
- 9 sites in Sweden
- Volunteers
- 55 people
- Sponsor
- Lund University
Chronic Low Back Pain
ReActiv8 Post Market Surveillance Registry
To gather data on the long-term safety of ReActiv8 and identify any residual risks by reporting all Serious Adverse Device Effects as well as performance and health care utilization through two years post-implant.
- Trial name
- ReActiv8-C (NCT03255200)
- Testing
- ReActiv8 Implantable Stimulation System
- Where
- 5 sites in Germany
- Volunteers
- 87 people
- Sponsor
- Mainstay Medical
Osteoarthritis, Rheumatoid Arthritis
Evaluation Of Efficacy And Safety Of Norspan In Moderate To Severe Pain Due To Osteoarthritis, Rheumatoid Arthritis, Joint/Muscle Pain
The purpose of this study is to assess the efficacy of the buprenorphine transdermal patch (Norspan® or Sovenor® transdermal patch) in patients with chronic non-malignant pain of moderate to severe intensity due to…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Lower Back Pain, Joint Pain
- Trial name
- NCT01961271
- Testing
- Buprenorphine transdermal patch
- Where
- 16 sites in Hong Kong, Philippines and 1 more
- Volunteers
- 114 people
- Sponsor
- Mundipharma Pte Ltd.
Low Back Pain, Chronic Pain
Effect of Music and Other Audio Recordings for Chronic Pain in Aging Adults
The long-range goal is to reduce suffering and establish alternative options for older adults experiencing pain. This is a randomized controlled study examining the effect of music on pain management in older adults.
- Conditions
- Low Back Pain, Chronic Pain, Sleep, Aging
- Trial name
- NCT04785963
- Testing
- Music with Suggestion, Pain Information, Music
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Baylor University
Chronic Low Back Pain
Chronic Pain Attitudes Medical and Physiotherapy Students
This is an analysis of data collected from 2009-2014 from medical students at GCU and physiotherapy students at UoG measuring attitudes towards patients with chronic low back pain and their functionality.
- Trial name
- NCT03902626
- Testing
- Physiotherapy students, Medical students
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Teesside University
Low Back Pain
Effectiveness of Therapeutic Alliance and Minimal Intervention for Chronic Low Back Pain
This study aims to evaluate the effectiveness of minimal intervention and therapeutic alliance in pain, specific and general disability, global perceived effect, empathy, credibility and expectation of improvement in patients…
- Trial name
- TalkBack (NCT02497625)
- Testing
- Positive Therapeutic Alliance, Usual care, Control group
- Where
- Brazil
- Volunteers
- 222 people
- Sponsor
- Universidade Cidade de Sao Paulo
Chronic Non-specific Low Back Pain
Efficacy and Safety of VER-01 in the Treatment of Patients With Chronic Non-specific Low Back Pain
Analysis of the efficacy, maintenance of efficacy, long-term safety, and investigation of the potential for dependence and abuse and the effect of abrupt drug withdrawal of VER-01 in the treatment of patients with chronic…
- Trial name
- NCT04940741
- Testing
- VER-01
- Where
- Germany
- Volunteers
- 820 people
- Sponsor
- Vertanical GmbH
Low Back Pain
Reliability and Responsiveness of One Questionnaire Used on a Low Back Pain Population
The purpose of this study is to determine the reliability and responsiveness of the Pain Self-Efficacy Questionnaire (PSEQ) in a chronic low back pain (CLBP) population referred to The Danish Rheumatism Associations´…
- Trial name
- NCT02892656
- Where
- 2 sites in Denmark
- Volunteers
- 152 people
- Sponsor
- Sano
Low Back Pain, Sleep Hygiene
The Effect of Breathing Exercise and Stabilization Exercise With Chronic Low Back Pain
The aim of this study is to compare the effect of sleep hygiene, breathing exercises, and stabilization exercises on pain, sleep quality, and anxiety level in patients with non-specific chronic low back pain.
- Conditions
- Low Back Pain, Sleep Hygiene, Anxiety
- Trial name
- NCT05212753
- Testing
- Conventional physical therapy, Lumbar stabilization exercises, Breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Low Back Pain
The Effect of Yoga and Stabilization Exercises in Individuals With Chronic Low Back Pain
Although exercise has been shown to be effective in low back pain in the literature, there is no conclusion about which exercise is superior to the other.
- Trial name
- NCT04787094
- Testing
- Yoga, Spinal Stabilization Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Hacettepe University
Low Back Pain
Effect of Thread-Embedding Acupuncture at EX-B2 Acupoint on Pain Intensity and Quality of Life in Chronic Low Back Pain
The goal of this clinical trial is to learn whether thread-embedding acupuncture (TEA) is more effective than sham thread-embedding acupuncture in treating adults with chronic low back pain.
- Trial name
- NCT07337187
- Testing
- Thread-embedding acupuncture
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Lumbar Spine Surgery, Chronic Low-back Pain
Telehealth Mindfulness After Spine Surgery
The goal of this pilot clinical trial is to compare two behavioral interventions for patients who are recovering from lumbar spinal surgery for a degenerative spine condition. The study aims to answer the following questions: 1.
- Conditions
- Lumbar Spine Surgery, Chronic Low-back Pain, Postsurgical Pain
- Trial name
- NCT05698914
- Testing
- Telehealth mindfulness-based intervention (MBI), Telehealth Education
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Vanderbilt University Medical Center
Low Back Pain
Effects of Diaphragmatic Manual Therapy in Chronic Low Back Pain
This study is a double-blind randomized clinical trial with two arms which aims to study the effects of diaphragmatic treatment in patients with nonspecific low back pain.
- Trial name
- NCT02343185
- Testing
- manual therapy with diaphragmatic treatment
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Cardenal Herrera University
Chronic Low Back Pain
Effectiveness of Electrotherapy Techniques to Treat Low Back Pain
Objective: The aim of this investigation was compare the effectiveness of transcutaneous electrical nerve stimulation (TENS) and interferential currents (IC) on chronic low back pain.
- Trial name
- TENBACK (NCT02297685)
- Testing
- Transcutaneous nerve stimulation, Interferential currents
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Camilo Jose Cela University
Chronic Low-back Pain
Effectiveness of Pain Neuroscience Education Compared to a Conventional Education for Patients With Chronic Low Back Pain
The hypothesis is that pain biology education, combined with a rehabilitation program, reduces disability to 3 months, compared to conventional spinal physiology education.
- Trial name
- EVAL-PNE (NCT04179708)
- Testing
- Pain Neuroscience Education, Conventional education
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Lille
Ulcer
Efficacy and Safety Study of HZT-501 in Subjects Requiring Nonsteroidal Anti-Inflammatory Drug (NSAID) Treatment
The purpose of this study is to evaluate whether HZT-501 is effective in reducing the rate of development of ibuprofen-associated ulcers in patients who require long-term daily use of ibuprofen.
- Trial name
- NCT00450216
- Testing
- Ibuprofen/famotidine, Ibuprofen
- Volunteers
- 906 people
- Sponsor
- Amgen
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