Clinical trials: Chronic Lung DIsease
Chronic Obstructive Pulmonary Disease (COPD)
Aides in Respiration Health Coaching for COPD
This study examined whether health coaches can improve the management of chronic obstructive pulmonary disease (COPD) in a population of vulnerable patients cared for in 'safety-net' clinics.
- Trial name
- AIR (NCT02234284)
- Testing
- Health Coaching
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- University of California, San Francisco
Chronic Obstructive Pulmonary Disease
Two Different Dosages of Nebulized Steroid Versus Parenteral Steroid in the Management of COPD Exacerbations
Chronic obstructive pulmonary disease (COPD) is a common disease that has a chronic and progressive course. Patients with COPD may have exacerbations one to four times in a year.
- Trial name
- NCT01865500
- Testing
- Budesonide 4 mg, Budesonide 8 mg, Metil prednisolone
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ataturk University
Chronic Obstructive Lung Disease
Improvement of Sleep in COPD Patients Through Inhalation Management Education by Nurse.
This study aims to investigate whether inhalation management education provided by nurses improves sleep quality in patients with COPD.
- Trial name
- NCT07311499
- Testing
- inhalation management education
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Kumamoto University
Chronic Obstructive Pulmonary Disease
PT003 MDI Dose Confirmation Study
The primary objective of this study is to demonstrate efficacy of PT003 MDI relative to its individual components (PT001 MDI and PT005 MDI) in patients with moderate to severe chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT01349816
- Testing
- PT003, PT001, PT005
- Where
- 13 sites in United States
- Volunteers
- 185 people
- Sponsor
- Pearl Therapeutics, Inc.
Pulmonary Disease, Chronic Obstructive
Investigation of Walking Training With Different Slope Types in COPD Patients
Chronic obstructive pulmonary disease (COPD) is a disease that continues to generate a great deal of research and this research must continue, both because it is not completely curable and because of the large patient population.
- Trial name
- NCT06283004
- Testing
- Downhill walking training, Level walking training, Uphill walking training
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Acibadem University
Pulmonary Disease, Chronic Obstructive, Generalized Chronic Periodontitis
The Association of SERPINA1 Gene Disturbance in Patients With Lung and Gum Disorders
Chronic obstructive pulmonary disease and periodontitis are chronic inflammatory diseases. The study aims to determine if the genetic polymorphism of SERPINA1 gene in patients with COPD serve as a risk factor for developing…
- Trial name
- SA1PLG (NCT02498938)
- Testing
- SERPINA1 gene
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
COPD, Self-management Behaviors
Comprehensive Self-management Support for COPD Patients
The study team will adapt and expand an effective model of asthma self-management support for patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- SAMBA COPD (NCT04533412)
- Testing
- Self-management barrier support, Basic COPD Education
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Obstructive Pulmonary Disease (COPD)
ALK27-001: A Study of Trospium Inhalation Powder (TrIP)Administered to Subjects With COPD
The purpose of this study was to evaluate the efficacy, safety, and tolerability of single doses of trospium inhalation powder (TrIP) administered to subjects with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT00801684
- Testing
- TrIP-2D, TrIP-2SS, TrIP-2SS + Foradil
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Alkermes, Inc.
Interstitial Lung Disease, Chronic Obstructive Pulmonary Disease
Continuous Versus Demand-Based Oxygen in Patients With Fibrotic Interstitial Lung Disease and Chronic Obstructive Pulmonary Disease
The goal of this randomised clinical trial is to compare the efficacy of exertional oxygen delivery by continous versus demand-based flow systems in patients with fibrotic Interstitial lung disease and chronic obstructive…
- Trial name
- OXYODE (NCT06767904)
- Testing
- Continous Oxygen by Bottles, Demand oxygen by Portable Concentrator
- Volunteers
- 60 people
- Sponsor
- Sissel Kronborg-White
Post-COVID Conditions
Cardiovascular and Psychological Consequences of COVID-19
The study will assess cardiac and psychological profile at 2-3 months after recovery from COVID-19 infection.
- Trial name
- NCT05758649
- Where
- Italy
- Volunteers
- 104 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
COPD
Inspiratory Muscle Training in COPD
This proposal aims at evaluating an inspiratory muscle training (IMT) method not previously tested in COPD called the Test of Incremental Respiratory Endurance (TIRE).
- Trial name
- NCT03438019
- Testing
- PrO2, Threshold Inspiratory Muscle Trainer
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Miami VA Healthcare System
Chronic Obstructive Pulmonary Disease
Role of Fibrocytes in the Bronchial Remodelling of Chronic Obstructive Pulmonary Disease
Airway remodelling is an abnormal tissue repair following bronchial inflammation, which contributes to none reversible pathological features, such as bronchial and peri-bronchial fibrosis.
- Trial name
- FIBROCHIR (NCT01692444)
- Testing
- analyse the distribution and quantify the number of the peri-bronchial and blood circulating fibrocytes in patients
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Pulmonary Disease, Chronic Obstructive, Asthma COPD
Impact of a Mobile Phone and Educational Intervention
The purpose of this pilot study was to: 1. partner with African American churches to increase awareness of COPD. 2. use a community-based approach to facilitate early detection of COPD in the church setting.
- Trial name
- NCT06878898
- Testing
- Education and mobile phone text-messaging, Education only
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Kent State University
Chronic Obstructive Pulmonary Disease (COPD)
Physical Training and Heart Rate Variability in COPD
To contrast the potential effects of physical exercise training program (PTP) of a 6 versus 12 weeks on cardiac autonomic modulation by linear and non-linear heart rate variability (HRV) indices and functional capacity in…
- Trial name
- NCT01889563
- Testing
- Physical Exercise Training Program Exercise
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Federal de Sao Carlos
Severe Chronic Obstructive Pulmonary Disease
Breathing Control Exercises in Patients With Chronic Obstructive Pulmonary Disease.
The purpose of this study is to test whether breathing control exercises embedded in occupational therapy sessions have an impact on quality of life and dyspnea in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT05199987
- Testing
- Standard Occupational Therapy, Occupational Therapy with Breathing Control Exercises
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
COPD, Chronic Diseases
A Project Ensuring Quality and Cooperation in the Chronic Obstructive Pulmonary Disease (COPD) Treatment
The purpose of this study is to ensure the quality of the COPD treatment in primary care by implementing planned follow-up visits, where the disease condition is evaluated and optimised in accordance with the national COPD…
- Trial name
- KOSMOS (NCT00772733)
- Where
- 11 sites in Denmark
- Volunteers
- 936 people
- Sponsor
- AstraZeneca
Acute Respiratory Diseases
Voice, Dyspnea and Acute Respiratory Failure
Breathing is an automatic vital function that has the peculiarity of being controllable voluntary for actions other than breathing.
- Trial name
- LocuPnée-H (NCT05340933)
- Testing
- Voice registration
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Obstructive Pulmonary Disease
COPD Rehabilitation in Primary and Secondary Health Care
Pulmonary rehabilitation of COPD patients are implemented in a non-randomized manner in two settings: primary and secondary health care. The effect on quality of life and hospitalizations will be evaluated
- Trial name
- NCT00320333
- Testing
- pulmonary rehabilitation programme
- Where
- 2 sites in Denmark
- Volunteers
- 120 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Pulmonary Disease, Chronic Obstructive, Smoking
Modeling Bronchial Epithelium Modifications Associated With COPD Using iPS
The primary objective of this study is to to verify the feasibility of obtaining and comparing two epithelia in two populations based on the following experiments: Differentiation of an Induced Pluripotent Stem cell (iPS) clone…
- Trial name
- INVECCO (NCT03181204)
- Testing
- Bronchial biopsy, Skin biopsy, Blood sample
- Where
- France
- Volunteers
- 11 people
- Sponsor
- University Hospital, Montpellier
Cough
Evaluation of the Three-Seeds Mixture Treatment in Chronic Obstructive Pulmonary Disease Patients
The purpose of this study is to test whether the three-seeds mixture tea reduces sputum and/or cough in COPD patients, and if so, to evaluate whether the three-seeds mixture changes the lung microbiome.
- Trial name
- NCT03926884
- Testing
- Three-seeds mixture, Control
- Volunteers
- 80 people
- Sponsor
- Veterans Affairs Medical Center, Miami