Clinical trials: Chronic Medical Conditions
Chronic Pain
Defense Health Agency- Development of a Medical Device Utilizing an EEG-Based Algorithm for the Objective Quantification of Pain
PainQx, with the support of the Department of Defense (Contract #W81XWH-21-C-0034), is conducting a study to collect electroencephalography (EEG) data from people with chronic pain in order to develop algorithms than will…
- Trial name
- PQXDOD1 (NCT05215184)
- Testing
- Zeto WR19 EEG Recording
- Where
- 5 sites in United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- PainQx, Inc
Low Back Pain, Recurrent
Evaluation of Performances and Safety of the Medical Device Blueback® Physio for Patients With Chronic Low Back Pain
The main objective of this clinical investigation is to show the superiority of a rehabilitation based on the use of Blueback® Physio compared to a rehabilitation without the use of Blueback® Physio in terms of reducing the time…
- Trial name
- ABC-TRACC (NCT04592094)
- Testing
- Blueback® Physio
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Blueback
Constipation, Constipation; Neurogenic
MOWOOT Device to Treat Constipation in Adults
The aim was to assess the safety and effectiveness of the automatic colon-specific massage with the MOWOOT device for patients suffering from chronic constipation due to Multiple Sclerosis, Parkinson Disease (NBD) or other…
- Conditions
- Constipation, Constipation; Neurogenic, Constipation Chronic Idiopathic
- Trial name
- NCT04262752
- Testing
- intermittent colonic exo-peristaltic massage treatment with the MOWOOT medical device
- Where
- 3 sites in Spain, United Kingdom
- Volunteers
- 100 people
- Sponsor
- usMIMA S.L.
Health Services Accessibility, Rural Health
Health Ahead Comparative Effectiveness Study
The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening on the path toward a fully automated screening…
- Conditions
- Health Services Accessibility, Rural Health, Medically Underserved Area, Preventive Health Services
- Trial name
- HACE (NCT07669168)
- Testing
- AI-Assisted Screening Interpretation (AI Reads), Human-Only Screening Interpretation
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- William Brandenburg, MD
End Stage Renal Disease (ESRD), End Stage Renal Disease on Dialysis
EXtension of Tablo TrEatmeNt Duration Registry
Observational, retrospective and prospective, multicenter, post-market study of the Tablo Hemodialysis System in hospitalized participants with End-Stage Kidney Disease or Acute Kidney Injury who are prescribed renal replacement…
- Conditions
- End Stage Renal Disease (ESRD), End Stage Renal Disease on Dialysis, Acute Kidney Injury
- Trial name
- XTEND (NCT04912050)
- Testing
- Tablo Hemodialysis System
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Outset Medical
Chronic Pain
Expanded Development of a Medical Device Utilizing an EEG-Based Algorithm for the Objective Quantification of Pain
PainQx is conducting a study to collect electroencephalography (EEG) data from 250 people with chronic pain and 50 healthy controls in order to develop algorithms that will objectively assess the level of pain a person is…
- Trial name
- NCT04585451
- Testing
- ALGOS System
- Where
- 5 sites in United States
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- PainQx, Inc
Chronic Pain
Intrathecal Morphine Compared to Conventional Medical Management for Pain Control and Opioid-related Side Effects
This study compares two different ways to treat pain. The two ways are: 1. continuing to take current pain medication(s) or 2. receiving morphine, a pain medication from a drug pump (a system to deliver drug to your body) that is…
- Trial name
- CONVERT-TDD (NCT01924182)
- Testing
- SynchroMed Infusion System and Intrathecal Morphine Sulfate, Conventional Medicine
- Where
- 6 sites in United States
- Volunteers
- 7 people
- Sponsor
- MedtronicNeuro
Venous Disease, Quality of Life
Consumer Study for the Evaluation of the Usability and Efficacy of One Medical Device in Venous Return
The primary goal of this study is to assess in vivo the efficacy of the insoles in improving venous return in subjects affected by this problem after 14 days of medical device use, by self-assessment, filling-in questions…
- Conditions
- Venous Disease, Quality of Life, Symptoms and Signs
- Trial name
- NCT06153680
- Testing
- Insoles
- Where
- Portugal
- Volunteers
- 52 people
- Sponsor
- Millet Innovation
Pulmonary Disease, Chronic Obstructive
A Study in South Korea Using Medical Records to Look at Different Treatments for Chronic Obstructive Airway Disease (COPD)
Non-interventional, Single-country study based on existing data from medical records of COPD patients treated with LAMA or fixed dose combination of ICS/LABA
- Trial name
- NCT04172701
- Testing
- Long-acting Muscarinic Antagonists (LAMA), Inhaled corticosteroid (ICS)/Long-acting Beta Agonists (LABA)
- Where
- South Korea
- Volunteers
- 9,284 people
- Sponsor
- Boehringer Ingelheim
Chronic Pain
Impact of QoLibri Medical Device on the Consequences of Chronic Pain: a Randomized Controlled Trial
A superiority study evaluating the impact of the QoLibri Software as Medical Device on functional and psychological consequences of chronic pain in primary care patients.
- Trial name
- QoLiDoc (NCT06841276)
- Testing
- QoLibri Digital Therapy
- Where
- France
- Volunteers
- 410 people
- Sponsor
- Novesia
Pain, Acute, Pain, Chronic
Evaluation of the Effect of the AI500™ SINGLE-DOSE GEL Medical Device in Patients With Reduced Knee Function
Evaluation of the effect of the AI500™ SINGLE-DOSE GEL medical device in patients with reduced knee function
- Conditions
- Pain, Acute, Pain, Chronic, Knee Injuries, Knee Osteoarthritis
- Trial name
- NCT05886608
- Testing
- AI 500™ SINGLE-DOSE GEL
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Contrad Swiss SA
Chronic Kidney Diseases, Renal Disease
Evaluation of Renastep
Evaluation of Renastep is a 28-day long, prospective nutritional study that will recruit 15 patients aged between 3 and 18 years of age with Chronic Kidney Disease.
- Trial name
- Renastep (NCT03602937)
- Testing
- Renastep
- Where
- 3 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Vitaflo International, Ltd
Chronic Low-Back Pain, Refractory Pain
Spinal Cord Stimulation vs. Medical Management for Low Back Pain (DISTINCT)
The objective of this study is to evaluate the efficacy of BurstDR dorsal column stimulation, compared with conventional medical management, in improving pain and back-related physical function in subjects suffering with chronic…
- Conditions
- Chronic Low-Back Pain, Refractory Pain, Neuropathic Pain
- Trial name
- NCT04479787
- Testing
- Spinal Cord Stimulation, Conventional Medical Management
- Where
- 30 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Devices
Chronic Pain, Lower Back Pain Chronic
Lumbar Injectrode Feasibility Evaluation
The goal of this non-significant risk study is to determine whether stimulation with transcutaneous waveforms applied on the outside of the body and subcutaneously conducted to the lumbar medial branch nerve elicits visible (via…
- Trial name
- LIFE (NCT06206356)
- Testing
- PNS Injectrode F1
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Neuronoff, Inc
Chronic Kidney Disease, Type 2 Diabetes Mellitus
A Study Called FINE-REAL to Learn More About the Use of the Drug Finerenone in a Routine Medical Care Setting
This is an observational study in people with chronic kidney disease (CKD) and type 2 diabetes (T2D) who will be receiving finerenone. Kidneys filter extra water and waste out of the blood and make urine.
- Trial name
- NCT05348733
- Testing
- Kerendia (Finerenone, BAY94-8862)
- Where
- 56 sites in United States, Argentina and 17 more
- Volunteers
- 4,613 people
- Sponsor
- Bayer
Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Mantle-Cell
Clinical Outcomes of Chronic Lymphocytic Leukemia (CCL) and Mantle Cell Lymphoma (MCL) Participants Treated With Ibrutinib: A Medical Chart Review From India
The purpose of this study is to describe the effectiveness (overall response rate [ORR] and time to progression [TPP]) of Ibrutinib therapy in participants with chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL).
- Trial name
- NCT03476655
- Testing
- Ibrutinib
- Where
- 8 sites in India
- Volunteers
- 40 people
- Sponsor
- Johnson & Johnson Private Limited
Chronic Pain, Neck Pain
A Study of Cybis™ 10:25 THC:CBD Oil in Adults With Chronic Back/Neck Pain
This is a non-randomised, single arm, open-label study of medical cannabis, Cybis™ 10:25, in participants with chronic back or neck pain in which participants receive escalating doses of Cybis™ 10:25.
- Conditions
- Chronic Pain, Neck Pain, Back Pain, Pain
- Trial name
- CYDEPS (NCT04976738)
- Testing
- Cybis™ 10:25 THC:CBD oil
- Where
- 2 sites in Australia
- Volunteers
- 28 people
- Sponsor
- Cymra Life Sciences
Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia
Spectroscopic Assessment of Tissue Oxygenation Changes During Vascular Surgery
This study is a single-center, observational study designed to collect tissue spectrometric data related to tissue oxygenation.
- Conditions
- Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia, Ischemia Vascular, Tissue Ischemia
- Trial name
- NCT07786623
- Volunteers
- 30 people
- Sponsor
- Spectrocor
Acute Respiratory Distress Syndrome (ARDS), Pneumonia
Medical Device Clinical Trial Without CE Marking to Evidence Safety and Performance of the INBENTUS VERSATILE Ventilator in Patients Requiring Assisted/Controlled Mechanical Ventilation and Weaning.
Pre-market clinical trial on 81 aldults participants to evidence safety and performance of the non-CE-marked medical device INBENTUS VERSATILE ventilator.
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Pneumonia, COPD (Chronic Obstructive Pulmonary Disease), Postoperative Respiratory Distress
- Trial name
- NCT07432191
- Testing
- INBENTUS VERSATILE
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Iconic Solutions By Murcia SL
Venous Disease, Quality of Life
Blinded User Study for the Evaluation of the Acceptability and Efficacy of One Medical Device in Venous Return in Comparison With a Control Group
The primary goal of this study is to assess in vivo the efficacy of the insoles, in improving venous return in subjects affected by this problem after 14 days of the initial measurements, by self-assessment, filling-in questions…
- Conditions
- Venous Disease, Quality of Life, Symptoms and Signs
- Trial name
- NCT06395025
- Testing
- Insoles
- Where
- Portugal
- Volunteers
- 110 people
- Sponsor
- Millet Innovation