Clinical trials: Chronic Mental Illness
Post-Traumatic Stress Disorder
Propranolol in Post Traumatic Stress Disorder
Problem and Objectives: There is currently no pharmacological treatment for curing post traumatic stress disorder (PTSD). The investigators will test whether propranolol when given immediately after trauma evocation is able to…
- Trial name
- Reductrauma (NCT00465608)
- Testing
- propranolol
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Toulouse
Critical Illness, Chronic Disease
Improving Communication About Serious Illness
The purpose of this study is to improve care delivered to patients with serious illness by enhancing communication among patients, families, and clinicians in the outpatient setting.
- Conditions
- Critical Illness, Chronic Disease, Terminal Care, Palliative Care
- Trial name
- ICSI (NCT01933789)
- Testing
- Communication Feedback Form for Patients with Serious Illness
- Where
- 6 sites in United States
- Volunteers
- 817 people
- Sponsor
- University of Washington
Mental Disorders, Severe, Mental Illness Persistent
Physical Activity to Reduce Cardiometabolic Risk in Adults With Serious Mental Illness (PARCS) Study
The aim of this project is to trial the protocol of a park-based physical activity (PA) intervention in adults with serious mental illness (SMI) in a community mental health center's peer support program.
- Trial name
- PARCS (NCT05457179)
- Testing
- Park-based physical activity, Active Control
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Kansas State University
Chronic Pain, Opioid-use Disorder
Imaging the Effects of rTMS on Chronic Pain
Chronic pain is highly prevalent in patients with opioid use disorder on methadone maintenance therapy, and associated with problems related to psychosocial functioning, medical and psychiatric health, and substance craving and…
- Trial name
- NCT02687360
- Testing
- Active rTMS treatment
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- New York State Psychiatric Institute
Chronic Pain
Mixed Reality-Based Rehabilitation Software for Chronic Secondary Musculoskeletal Pain
This study evaluated the efficacy and safety of a mixed reality-based chronic pain rehabilitation software (PK-MPT) for adults with chronic secondary musculoskeletal pain.
- Trial name
- NCT06936059
- Testing
- Mixed Reality based analgesic therapy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Chronic Obstructive Pulmonary Disease (COPD)
Effects of Walking and Home-Based Pulmonary Rehabilitation on Anxiety and Sleep Quality
Although pulmonary rehabilitation plays an important role in increasing exercise tolerance and reducing hospitalizations in patients with chronic obstructive pulmonary disease (COPD), adherence to treatment is often low.
- Trial name
- NCT06862713
- Testing
- pulmonary rehabilitation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
Tobacco Use Disorder
Maintaining Abstinence in Chronic Cigarette Smokers - 1
The purpose of this study is to evaluate the extended pharmacological and psychological treatment for chronic cigarette smokers.
- Trial name
- NCT00087880
- Testing
- Bupropion and NRT
- Where
- United States
- Volunteers
- 407 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Analgesia, Fibromyalgia
Retrospective Study of Psychoattitudinal Patterns in Patients With Fibromyalgia Receiving Antalgic Therapy
Fibromyalgia (FM) is a widespread and invalidating disease that requires a multidisciplinary approach. Particularly, the psychiatric component seems to influence the algological management of these patients.
- Conditions
- Analgesia, Fibromyalgia, Pain, Chronic, Pain Syndrome
- Trial name
- NCT04623827
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- University of Bologna
Schizophrenia
Relapse Prevention, RoW: Study to Evaluate Prevention of Relapse in Patients in Stable Chronic Schizophrenia Receiving Either Seroquel or Placebo
This study is being carried out to see if quetiapine (Seroquel) is effective in preventing patients from a schizophrenic relapse when studied for a long time (1 year) and if so, how it compares with non-active treatment.
- Trial name
- NCT00228462
- Testing
- Seroquel (quetiapine)
- Where
- 5 sites in Bulgaria, Poland
- Volunteers
- 197 people
- Sponsor
- AstraZeneca
First Episode Psychosis (FEP)
Self-administered COgnitive Personalized Training in Early Psychosis
The overall objective of SCOPe is to improve early intervention in psychosis by providing an innovative eHealth tool that will enable personalized cognitive training, adapted to the individual's cognitive abilities.
- Trial name
- SCOPe (NCT06634446)
- Testing
- a mobile application for cognitive training, video games
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Insomnia Chronic, Older People
Efficacy of Trazodone to Treat Insomnia in Older Adults (TRADITION Study)
This study aims to evaluate how effective trazodone is in treating insomnia in adults aged 65 years and older. The main question it aims to answer is : Is trazodone more effective than a placebo in reducing the severity of…
- Conditions
- Insomnia Chronic, Older People, Drug Therapy
- Trial name
- TRADITION (NCT06983080)
- Testing
- Trazodone 25 mg
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Attention Deficit Disorder With Hyperactivity, Asthma
Study of an Intervention to Improve Problem List Accuracy and Use
The aim of this study is to identify patients with problem list gaps and intervene to correct these gaps by creating clinical decision support interventions that alert providers to likely problem list gaps and offer clinicians…
- Conditions
- Attention Deficit Disorder With Hyperactivity, Asthma, COPD, Breast Cancer
- Trial name
- MAPLE (NCT01105923)
- Testing
- MAPLE
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Brigham and Women's Hospital
Opioid-Related Disorders, Opiate Addiction
A Prospective Investigation of the Risks of Opioid Misuse, Abuse, and Addiction Among Patients Treated With Opioids for the Treatment of Chronic Pain
The purpose of this study is to quantify the serious risks of prescription opioid misuse or abuse or opioid use disorder (OUD) associated with the long term use of opioid analgesics for management of chronic pain, among patients…
- Conditions
- Opioid-Related Disorders, Opiate Addiction, Narcotic Abuse, Drug Abuse
- Trial name
- NCT02751762
- Testing
- Observation Only
- Where
- 2 sites in United States
- Volunteers
- 3,600 people
- Sponsor
- Member Companies of the Opioid PMR Consortium
Hypertension, Diabetes
Arts & Health Education to Improve Health, Resilience, and Well-Being
This is an 8-week randomized controlled trial to help address health, resilience, and well-being. Participants are randomized into either a health education group or an arts-based health education group.
- Conditions
- Hypertension, Diabetes, Obesity, COPD
- Trial name
- NCT04154579
- Testing
- HeRe We Arts, HeRe We Ed
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Lisa Gallagher
Post COVID-19 Condition
Pilot Open Label Use of the Hi-OXSR for the Treatment of Post COVID-19 Cognitive Dysfunction
During the worldwide COVID-19 pandemic a large number patients reported different functional complaints one month or later after recovery from the acute infection.
- Trial name
- Hi-OXSR (NCT06379620)
- Testing
- Hi-OxSR Sequential Rebreathing mask (oxygen concentrator)
- Where
- Canada
- Volunteers
- 37 people
- Sponsor
- University Health Network, Toronto
Alzheimer Disease, Dementia
Pragmatic Trial of Video Education in Nursing Homes
This is a pragmatic cluster-randomized control trial (RCT) of an Advance Care Planning (ACP) Video Program for nursing home (NH) patients ≥ 65 years old who are cared for in 360 NH facilities (intervention arm n=119; control arm…
- Conditions
- Alzheimer Disease, Dementia, Heart Failure, Pulmonary Disease, Chronic Obstructive
- Trial name
- PROVEN (NCT02612688)
- Testing
- ACP Video Program
- Where
- 2 sites in United States
- Volunteers
- 197,692 people
- Sponsor
- Brown University
Chronic Pain, Psychological Disorders
Influence of Psychological Status on the Results of Pain Treatment in Patients With Gunshot and Mine-explosive Wounds
82.1% of patients with gunshot and mine-explosive wounds and wounds during hostilities in Ukraine have negative results of pain treatment, which leads to its chronicity.
- Trial name
- IPSRPTPGaM-EW (NCT05478642)
- Testing
- The Hospital Anxiety and Depression Scale.
- Where
- Ukraine
- Volunteers
- 2,215 people
- Sponsor
- Bogomolets National Medical University
Posttraumatic Stress Disorders, Chronic Insomnia
Integrated CBT-I and PE on Sleep and PTSD Outcomes (Impact Study)
This study aims to examine whether integrating insomnia and PTSD treatment will enhance sleep, PTSD, and quality of life outcomes.
- Trial name
- NCT02774642
- Testing
- CBTI-PE, Hygiene-PE
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- VA Office of Research and Development
End-Stage Renal Disease, Stroke
Assessing Cognitive fUnction and MEasuring the Cerebral circulatioN on HaemoDialysis
Stroke disease and cognitive impairment are common in patients established on haemodialysis (HD) for end-stage renal disease (ESRD). Further, initiation of HD appears to transiently increase the risk of stroke.
- Conditions
- End-Stage Renal Disease, Stroke, Cognition Disorders
- Trial name
- ACUMEN-HD (NCT02393222)
- Testing
- Observing effect of routine HD
- Volunteers
- 97 people
- Sponsor
- NHS Greater Glasgow and Clyde
Surface and Deep Dyspareunia
Physiotherapeutic Approach to Superficial and Deep Dyspareunia in Women With Chronic Pelvic Pain: Comparison Between In-person and Telehealth Care.
Adequate sexual function is considered an important factor in satisfaction and overall quality of life for both men and women. It is estimated 16% to 40% of women suffer from some form of sexual dysfunction, which is currently…
- Trial name
- NCT07658703
- Testing
- Face-to-face treatment, Telecare
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- University of Sao Paulo
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.