Clinical trials: Chronic Migraine, Headaches
Chronic Daily Headache
Intensive Meditation and Migraines: Effects on Health and Well Being
Participants completing training in intensive meditation and continuing frequent practice for one year would experience reduced frequency, duration and severity of headaches along with improved awareness of the triggers of their…
- Trial name
- NCT00663585
- Testing
- Vipassana Meditation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Johns Hopkins University
Chronic Migraine Headache, Chronic Migraine, Headache
EFFECT OF ANODAL TRANSCRANIAL DIRECT CURRENT STIMULATION (tDCS) OF PRIMARY MOTOR CORTEX ON HEADACHE FREQUENCY IN PATIENTS WITH CHRONIC MIGRAINE
Migraine is a common, heterogeneous neurological disorder affecting approximately 10-15% of the global population and is the third most prevalent disease worldwide.
- Trial name
- NCT07743814
- Testing
- Transcranial Direct Current stimulation
- Where
- India
- Volunteers
- 32 people
- Sponsor
- Dr. Ram Manohar Lohia Hospital
Chronic Migraine
A Study to Evaluate the Tolerability of Botox and Topiramate or Botox and Placebo and Effect on Cognitive Efficiency
The purpose of this study is to evaluate sustained tolerability, quality of life, and change in cognitive efficiency following treatment with OnabotulinumtoxinA and daily topiramate vs.
- Trial name
- NCT01700387
- Testing
- onabotulinumtoxinA, Topiramate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cady, Roger, M.D.
Sphenopalatine Block, BOTOX
Sphenopalatine Block Versus BOTOX in Management of Chronic Migraine
This trial compares the efficacy and safety of sphenopalatine ganglion block (SPGB) and intramuscular BOTOX injection in chronic migraine.
- Conditions
- Sphenopalatine Block, BOTOX, Chronic Migraine
- Trial name
- NCT06974617
- Testing
- Sphenopalatine block, Botulinum Toxin Type A
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University
High Frequency Episodic Migraine and Chronic Migraine
"Longitudinal Analysis of Amylin Levels in Migraine Patients Undergoing an Anti- CGRP/CGRPr Treatment"
Migraine, a complex and multifaceted disorder, remains only partially understood, with therapeutic strategies often limited by individual variability in response.
- Trial name
- NCT06692088
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Fundación Marques de Valdecilla
Migraine
Study of Quality of Life in Subjects With Chronic or High-frequency Episodic Migraine and Associated Comorbidities Treated With Erenumab
Migraine is a very common, neurological disorder, characterized by recurrent episodes of headache, potential progression to more frequent and severe attack patterns, and associated symptoms.
- Trial name
- COMIG (NCT04114630)
- Testing
- erenumab 70mg/mL
- Where
- 27 sites in Spain
- Sponsor
- Novartis Pharmaceuticals
Migraine
Comparing Efficacy and Safety of 2 Dose Regimens of Subcutaneous Administration of TEV-48125 Versus Placebo for the Preventive Treatment of Chronic Migraine
The study is being conducted to evaluate two doses of TEV-48125 in adult patients with chronic migraine
- Trial name
- NCT02621931
- Testing
- Fremanezumab
- Where
- 273 sites in United States, Canada and 7 more
- Volunteers
- 1,130 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Migraine
Migraine--Investigational Treatment of Migraine With Noninvasive Brain Stimulation. (tDCS- Migraine)
The purpose of this study is to determine whether a painless and noninvasive procedure called Transcranial Direct Current Stimulation (tDCS) can be an effective therapy for the treatment of migraine and migraine-associated pain.
- Trial name
- NCT00521196
- Testing
- DC Stimulator (Transcranial Direct Current Stimulator)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Beth Israel Deaconess Medical Center
Chronic Migraine, Headache
Effect of Auricular Vagus Nerve Stimulation in Women With Migraine Disease
The aim of the study was to investigate the effectiveness of non-invasive auricular vagus nerve stimulation on pain and pulse variability in women aged 18-55 years with migraine.
- Trial name
- NCT05748535
- Testing
- Auricular Vagus Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bahçeşehir University
Migraine Disorders
BOTOX® Prophylaxis in Patients With Chronic Migraine
This is a post authorization observational study to monitor the utilization practices and describe the safety profile of BOTOX® in clinical practice for the prophylactic treatment of headaches in adult patients with chronic…
- Trial name
- NCT01432379
- Testing
- botulinum toxin Type A
- Where
- 4 sites in Germany, Spain and 2 more
- Volunteers
- 1,168 people
- Sponsor
- Allergan
Chronic Migraine, Headache
Efficacy of GONB in Patients of Migraine
The study was carried to determine the analgesic efficacy of greater occipital nerve block in patients of migraine. It was a randomised controlled which took place from april 2022 - october 2022.
- Trial name
- NCT05679765
- Testing
- Greater Occipital Nerve Block with dexamethasone and lidocaine, Greater Occipital Nerve Block with 0.9% saline
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Pain Medicine Department
Chronic Migraine Headache, Psychologic Adaptation
Psychological Support for Chronic Migraine Patients Treated With Anti-CGRP (Anti-Calcitonin Gene-Related Peptide ) Monoclonal Antibodies
Chronic migraine is a disabling neurological condition that can significantly affect quality of life, emotional well-being, social participation, and daily functioning.
- Trial name
- MIG-PSY-CGRP (NCT07877493)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Central Hospital, Nancy, France
Primary Headache
Two US-guided Techniques for Greater Occipital Nerve Blocks
Headache is one of the most common reasons for patients to access healthcare. Greater occipital nerve (GON) block with local anesthetic and steroid has been described for the management of primary headache refractory to…
- Trial name
- GON (NCT02031822)
- Testing
- US-guided Greater Occipital Nerve Injection
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Chronic Migraine
Brief Interventions in Chronic Migraine
People with chronic migraine headaches face many challenges, including high levels of daily pain, disturbances to everyday activities and sleep, and problems with mood such as depression or anxiety.
- Trial name
- NCT05979337
- Testing
- Empowered Relief, Health Education (HE), Treatment as Usual
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Michigan
Chronic Migraine Headache, Transcranial Direct Current Stimulation
TCDS for the Treatment of Chronic Migraine
Migraine affects 1 in 7 people worldwide, but for those suffering from chronic migraine there is a need for safe, effective and well tolerated treatments.
- Trial name
- NCT07214454
- Testing
- Transcranial direct current stimulation (Nettle device) 2mA stimulation for 20 minutes per day
- Volunteers
- 20 people
- Sponsor
- University College, London
Migraine
Dietary Intervention for Migraine Relief
The goal of this clinical trial is to evaluate whether a low-glutamate diet can improve migraine symptoms in adults with migraine and to explore possible biological changes associated with dietary improvement.
- Trial name
- NCT07360405
- Testing
- Dietary training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- American University
Headache, Migraine
An Italian Randomized Open-label Study of Occipital Nerve Stimulation in the Treatment of Chronic Migraine Headache
The purpose of this study is to evaluate the safety and the efficacy of occipital nerve stimulation treating Chronic Migraine Headache
- Trial name
- Migraine (NCT00407992)
- Testing
- Occipital nerve stimulation ON, Occipital nerve stimulation off
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Chronic Headache, Chronic Headache Disorder
The Impact of Greater Occipital Nerve and Stellate Ganglion Block Treatments on Sleep in Chronic Headache Management
This study aims to evaluate the effect of Greater Occipital Nerve and Stellate Ganglion block treatments on sleep in patients with chronic headaches.
- Conditions
- Chronic Headache, Chronic Headache Disorder, Migraine
- Trial name
- NCT06646081
- Testing
- Greater Occipital Nerve Block, Stellate Ganglion Block
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Ankara Etlik City Hospital
Chronic Migraine, Headache, Refractory Migraine
Occipital Nerve Stimulation in Chronic Migraine
The goal of this clinical trial is to compare two different types of occipital nerve stimulation (BurstDR (dorsal root) microdosing versus Tonic) in chronic refractory migraine.
- Trial name
- NCT07087678
- Testing
- Prodigy internal pulse generator occipital nerve stimulator
- Volunteers
- 40 people
- Sponsor
- University College, London
Vestibular Migraine, Chronic Subjective Dizziness
Verapamil vs. Sertraline for Vestibular Migraine & Chronic Subjective Dizziness
Vestibular migraine (VM) and chronic subjective dizziness (CSD) commonly cause vertigo, unsteadiness and dizziness. Clinical investigators are studying these illnesses to understand them better.
- Trial name
- NCT01669304
- Testing
- Verapamil, Sertraline
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Mayo Clinic