Clinical trials: Chronic Musculoskeletal Pain
Back Pain, Neck Pain
Cross-Disciplinary Workplace Intervention Strategy for Chronic Musculoskeletal Disorders
Sickness absenteeism caused by MSDs is a persistent and expensive health challenge in all industrial countries including Switzerland.
- Conditions
- Back Pain, Neck Pain, Musculoskeletal Abnormalities
- Trial name
- NCT00369135
- Testing
- combined intervention
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Institut Universitaire Romand de Sante au Travail
Chronic Pain, Chronic Migraine
Neurologic Signatures of Chronic Pain Disorders
"Brain signatures" as objective measures of acute pain have been characterized with functional magnetic resonance image and machine learning technology.
- Conditions
- Chronic Pain, Chronic Migraine, Fibromyalgia
- Trial name
- NCT02747940
- Testing
- flunarizine and/or pregabalin
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Fibromyalgia
Comparison of Ketamine and Esketamine in Patients Suffering From Fibromyalgia Syndrome.
Ketamine and Esketamine intravenous perfusions can modulate chronic pain. The purpose of this study is to determine if Ketamine or Esketamine are favorable for outpatients suffering from fibromyalgia.
- Trial name
- KESK-FIQ (NCT04938713)
- Testing
- Ketamine 50 MG/ML, Esketamine 25 MG/ML
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Charleroi
Low Back Pain, Osteoarthritis
Long-term Open-Label Safety Study to Evaluate EN3409
The purpose of the long-terms study is to evaluate the safety, tolerability, and analgesic efficacy of EN3409 in subjects with moderate to severe chronic pain requiring continuous around-the-clock opioid analgesia for an extended…
- Conditions
- Low Back Pain, Osteoarthritis, Neuropathic Pain
- Trial name
- NCT01755546
- Testing
- EN3409
- Where
- 57 sites in United States
- Volunteers
- 304 people
- Sponsor
- BioDelivery Sciences International
Diabetic Neuropathy, Arthritis
Effect of Holofiber Socks and Bedding on Pain and Quality of Sleep in Subjects With Chronic Foot Pain
This study is designed to assess the effects of socks and bedding materials on foot pain, the level of blood oxygen existing in the feet and quality of sleep in subjects who have chronic foot pain from either diabetic neuropathy…
- Conditions
- Diabetic Neuropathy, Arthritis, Peripheral Arterial Disease, Plantar Fasciitis
- Trial name
- NCT00458497
- Testing
- Holofiber fabric, PET fabric
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Southern California Institute for Research and Education
Chronic Pain, Musculoskeletal Pain
Online Pain Education in Addition to Usual Care in Chronic Pain.
The lack of pain specialists limits users' access to non-pharmacological therapeutic pain control strategies. In this context, digital health programs can reduce the inequity of access to interventions, contribute to the…
- Trial name
- NCT05302180
- Testing
- Pain neuroscience education, Usual care
- Where
- Brazil
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Universidade Cidade de Sao Paulo
Insomnia Chronic, Osteoarthritis
Audio-visual Stimulation for Sleep Promotion in Older Adults With Osteoarthritis Pain
Background and Purpose: The purpose of the study is to test the efficacy of an audio-visual stimulation program for sleep promotion in adults with chronic pain.
- Conditions
- Insomnia Chronic, Osteoarthritis, Pain, Chronic
- Trial name
- NCT03441191
- Testing
- Audiovisual Stimulation
- Volunteers
- 30 people
- Sponsor
- University of Washington
Knee Pain, Chronic Osteoarthritis
ROSA Total Knee Post Market Study EMEA
This is a prospective, multicenter clinical study designed to facilitate the collection and evaluation of surgical workflow efficiency, patient pain and function outcome and adverse events data.
- Conditions
- Knee Pain, Chronic Osteoarthritis, Avascular Necrosis of the Femoral Condyle, Moderate Varus, Valgus or Flexion Deformities
- Trial name
- NCT04338893
- Testing
- Device: Persona Total Knee, Device: NexGen Total Knee, Device: Vanguard Total Knee
- Where
- 6 sites in Belgium, Germany and 3 more
- Volunteers
- 252 people
- Sponsor
- Zimmer Biomet
Chronic Musculoskeletal Pain
Neural Mobilization to Improve Chronic Musculoskeletal Pain in Older Adults
The goal of this clinical trial is to discover whether performing active neural mobilization exercises works to manage chronic musculoskeletal pain in older adults.
- Trial name
- NCT07449819
- Testing
- Active Neural Mobilization Exercises
- Where
- Portugal
- Volunteers
- 4 people
- Sponsor
- Aveiro University
Myofascial Trigger Points, Migraine
Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Knee Osteoarthritis(OA)
Chronic musculoskeletal pain (CMP) is a common disease in China, with a high incidence among the elderly, and has a significant impact on patients' quality of life. Knee osteoarthritis is a common type of CMP.
- Conditions
- Myofascial Trigger Points, Migraine, Cervicogenic Headache, Chronic Musculoskeletal Pain
- Trial name
- NCT07347028
- Testing
- MTrPs Injection, Intra-articular(IA) Injection
- Where
- China
- Volunteers
- 238 people
- Sponsor
- Beijing Tiantan Hospital
Rheumatoid Arthritis (RA, Chronic Pain
Integrative AI-Based Multiomic and Neurophysiological Profiling of Chronic Pain in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease in which pain remains the most prominent and burdensome symptom from the patient's perspective.
- Trial name
- RA-PAIN-AI (NCT07769619)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- 4th Military Clinical Hospital with Polyclinic, Poland
Temporomandibular Disorders (TMD)
Journaling Intervention for Temporomandibular Disorder (TMD) and Chronic Overlapping Pain
The goal of this clinical trial is to learn whether a 2-week gratitude journaling activity is feasible and acceptable for individuals with Temporomandibular Disorder (TMD) and chronic overlapping pain.
- Trial name
- NCT06977100
- Testing
- Gratitude, General Wellness
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Florida
Musculoskeletal Pain
Enhanced Biofeedback for Musculoskeletal Pain
The purpose of this study is to assess whether a novel, enhanced form of biofeedback can help individuals regulate their chronic musculoskeletal pain more effectively.
- Trial name
- NCT02920853
- Testing
- Biofeedback Training (BT-CPR), Biofeedback Training
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Tulsa
Musculoskeletal Pain, Neuropathic Pain
Association of High PainDETECT Scores With Pain Region and Diagnosis in Patients Attending a Musculoskeletal and Sports Medicine Clinic
This observational study aims to evaluate the relationship between PainDETECT questionnaire scores, pain regions, and clinical diagnoses in patients presenting to a musculoskeletal and sports medicine clinic.
- Trial name
- PD-MSK (NCT07356115)
- Testing
- No Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Uskudar University
Chronic Musculoskeletal Pain
Knowledge Beliefs and Expectations of Chronic Musculoskeletal Patients About Their Physiotherapy Program
The purpose of this study is to investigate the knowledge, beliefs and expectations of patients with chronic musculoskeletal pain about their physiotherapy program and the relationship that they built with physiotherapists.
- Trial name
- NCT05707559
- Where
- Greece
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Shoulder Joint Disorder
The Effectiveness of Megadose Shinbaro Pharmacopuncture for Patients With Chronic Shoulder Pain
This study is a prospective, case-control observational trial. The investigators will compare the Megadose Shinbaro Pharmacopuncture group to the control group to analyze the effectiveness of shoulder Megadose Shinbaro…
- Trial name
- NCT04222829
- Testing
- Megadose Shinbaro Pharmacopuncture
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Jaseng Medical Foundation
Chronic Musculoskeletal Pain
University of Michigan / Wayne State Chronic Pain Study
This study is designed to determine if a brief educational program can alter the attitudes and knowledge of individuals with chronic back pain, which is likely to be non-structural in nature.
- Trial name
- NCT03391661
- Testing
- Pain neuroscience education patient exercise, Health behavior control intervention
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Wayne State University
Chronic Pain, Musculoskeletal Pain Disorder
Cognitive Bias Modification for Interpretation Individuals With Chronic Musculoskeletal Pain
Cognitive Bias Modification for Interpretation (CBM-I) trains participants to interpret ambiguous information as neutral or benign, rather than interpret it as being related to pain.
- Trial name
- NCT06368362
- Testing
- Benign cognitive bias modification for interpretation, Pain-related cognitive bias modification for interpretation
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Quality of Life, Chronic Musculoskeletal Disease
Factors Affecting Quality of Life in Patient With Chronic Musculoskeletal Pain
This study included patients who applied to the physical therapy and rehabilitation outpatient clinic and were diagnosed with chronic low back pain and osteoarthrosis and met the criteria for participation in the study.
- Conditions
- Quality of Life, Chronic Musculoskeletal Disease, Chronic Pain
- Trial name
- NCT05298566
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Subacromial Pain Syndrome, Central Sensitisation
The Segmental Distribution of Hypersensitivity in Patients With Chronic Subacromial Pain Syndrome
This study aimed to determine the distribution of pain sensitivity according to body segments in patients with central sensitization associated with chronic subacromial pain syndrome (SPS).This cross-sectional study included…
- Trial name
- NCT06139120
- Testing
- Assessment of hypersensitivity
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Cukurova University